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Can krill oil from small crustaceans be a panacea that alleviates symptoms of knee osteoarthritis?
Luis Vitetta
doi : 10.1093/ajcn/nqac151
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 621–622
Fish oil–derived ω–-3 fatty acids—the missing ingredients to support muscle growth in people with chronic obstructive pulmonary disease
Clifton J Holmes, Bettina Mittendorfer
doi : 10.1093/ajcn/nqac166
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 623–624
Coffee consumption and disease networks
Marilyn C Cornelis, Rob M van Dam
doi : 10.1093/ajcn/nqac165
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 625–626
Fishing for resolution
Philip C Calder
doi : 10.1093/ajcn/nqac157
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 627–629
Adherence to the Mediterranean-style diet and high intake of total carotenoids reduces the odds of frailty over 11 years in older adults: Results from the Framingham Offspring Study
Courtney L Millar, Elise Costa, Paul F Jacques, Alyssa B Dufour, Douglas P Kiel, Marian T Hannan, Shivani Sahni
doi : 10.1093/ajcn/nqac130
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 630–639
The benefit of a Mediterranean-style diet in reducing frailty is not well established in older Americans.
Effect of a ketogenic diet versus Mediterranean diet on glycated hemoglobin in individuals with prediabetes and type 2 diabetes mellitus: The interventional Keto-Med randomized crossover trial
Christopher D Gardner, Matthew J Landry, Dalia Perelman, Christina Petlura, Lindsay R Durand, Lucia Aronica, Anthony Crimarco, Kristen M Cunanan, Annie Chang, Christopher C Dant, Jennifer L Robinson, Sun H Kim
doi : 10.1093/ajcn/nqac154
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 640–652
Consensus has not been reached on what constitutes an optimal diet in individuals with prediabetes and type 2 diabetes mellitus (T2DM), especially between low-carbohydrate options.
Arginine catabolism metabolites and atrial fibrillation or heart failure risk: 2 case-control studies within the Prevención con Dieta Mediterránea (PREDIMED) trial
Leticia Goni, Cristina Razquin, EstefanÃa Toledo, Marta Guasch-Ferré, Clary B Clish, Nancy Babio, Clemens Wittenbecher, Alessandro Atzeni, Jun Li, Liming Liang, Courtney Dennis, Ã�ngel Alonso-Gómez, Montserrat Fitó, Dolores Corella, Enrique Gómez-Gracia, Ramón Estruch, Miquel Fiol, Jose Lapetra, Lluis Serra-Majem, Emilio Ros, Fernando Arós, Jordi Salas-Salvadó, Frank B Hu, Miguel A MartÃnez-González, Miguel Ruiz-Canela
doi : 10.1093/ajcn/nqac139
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 653–662
Arginine-derived metabolites are involved in oxidative and inflammatory processes related to endothelial functions and cardiovascular risks.
Systematic review and meta-analysis examining the relationship between postprandial hypotension, cardiovascular events, and all-cause mortality
David J A Jenkins, Sandhya Sahye-Pudaruth, Khosrow Khodabandehlou, Fred Liang, Maaria Kasmani, Jessica Wanyan, Maggie Wang, Keishini Selvaganesh, Melanie Paquette, Darshna Patel, Andrea J Glenn, Korbua Srichaikul, Cyril W C Kendall, John L Sievenpiper
doi : 10.1093/ajcn/nqac158
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 663–671
Postprandial hypotension (PPH) has been reported to be associated with syncope, falls, adverse cardiovascular outcomes, and increased all-cause mortality. It has been reported to have an incidence as high as 30% in the elderly and persons with diabetes. We therefore performed a meta-analysis to determine the relation of PPH with cardiovascular disease (CVD) events and all-cause mortality.
Krill oil improved osteoarthritic knee pain in adults with mild to moderate knee osteoarthritis: a 6-month multicenter, randomized, double-blind, placebo-controlled trial
Welma Stonehouse, Bianca Benassi-Evans, Jana Bednarz, Andrew D Vincent, Stephen Hall, Catherine L Hill
doi : 10.1093/ajcn/nqac125
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 672–685
Osteoarthritis (OA) is a major cause of chronic pain and disability worldwide. Treatment generally focuses on symptom relief through nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesics, which may incur side effects. Krill oil, rich in anti-inflammatory long-chain (LC) omega-3 ( ω–3) PUFAs and astaxanthin, may be a safe and effective alternative treatment.
ω-3 polyunsaturated fatty acid supplementation improves postabsorptive and prandial protein metabolism in patients with chronic obstructive pulmonary disease: a randomized clinical trial
Mariëlle P K J Engelen, Renate Jonker, Hooriya Sulaiman, Helena L Fisk, Philip C Calder, Nicolaas E P Deutz
doi : 10.1093/ajcn/nqac138
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 686–698,
Disturbances in protein metabolism and impaired muscle health have been observed in chronic obstructive pulmonary disease (COPD). The ω-3 (n–3) PUFAs EPA and DHA are known for their anti-inflammatory and muscle health-enhancing properties.
A single, high-fat meal adversely affects postprandial endothelial function: a systematic review and meta-analysis
Juanita J Fewkes, Nicole J Kellow, Stephanie F Cowan, Gary Williamson, Aimee L Dordevic
doi : 10.1093/ajcn/nqac153
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 699–729
Endothelial dysfunction is a predictive risk factor for the development of atherosclerosis and is assessed by flow-mediated dilation (FMD). Although it is known that NO-dependent endothelial dysfunction occurs after consuming a high-fat meal, the magnitude of the effect and the factors that affect the response are unquantified.
Medical conditions associated with coffee consumption: Disease-trajectory and comorbidity network analyses of a prospective cohort study in UK Biobank
Can Hou, Yu Zeng, Wenwen Chen, Xin Han, Huazhen Yang, Zhiye Ying, Yao Hu, Yajing Sun, Yuanyuan Qu, Fang Fang, Huan Song
doi : 10.1093/ajcn/nqac148
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 730–740
Habitual coffee consumption has been associated with multiple health benefits. A comprehensive analysis of disease trajectory and comorbidity networks in relation to coffee consumption is, however, currently lacking.
Urinary potassium excretion and mortality risk in community-dwelling individuals with and without obesity
Stanley M H Yeung, Anne Nooteboom, Ewout J Hoorn, Joris I Rotmans, Liffert Vogt, Rudolf A de Boer, Ron T Gansevoort, Gerjan Navis, Stephan J L Bakker, Martin H De Borst
doi : 10.1093/ajcn/nqac137
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 741–749
Potassium intake has been shown to be inversely associated with blood pressure and premature mortality. Previous studies have suggested that the association between potassium intake and blood pressure is modified by obesity, but whether obesity similarly influences the association between potassium intake and mortality is unclear.
Pre-pregnancy fat intake in relation to hypertensive disorders of pregnancy
Mariel Arvizu, Lidia Minguez-Alarcon, Siwen Wang, Makiko Mitsunami, Jennifer J Stuart, Janet W Rich-Edwards, Bernard Rosner, Jorge E Chavarro
doi : 10.1093/ajcn/nqac145
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 750–758
Many studies have linked intakes of fat and of specific fatty acids during pregnancy with preeclampsia; however, information on the association of intake before pregnancy with hypertensive disorders of pregnancy (HDP) is scant.
Associations of serum n–3 and n–6 polyunsaturated fatty acids with prevalence and incidence of nonalcoholic fatty liver disease
Tiia N K Mäkelä, Tomi-Pekka Tuomainen, Sari Hantunen, Jyrki K Virtanen
doi : 10.1093/ajcn/nqac150
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 759–770,
Nonalcoholic fatty liver disease (NAFLD) is a major cause of liver diseases worldwide, and lifestyle and diet are significant factors in its development. Recent studies have suggested that dietary fat quality is associated with the development of NAFLD.
Causal associations of alcohol consumption with cardiovascular diseases and all-cause mortality among Chinese males
Chunyu Hu, Chunyan Huang, Jianxin Li, Fangchao Liu, Keyong Huang, Zhongying Liu, Xueli Yang, Xiaoqing Liu, Jie Cao, Shufeng Chen, Hongfan Li, Chong Shen, Ling Yu, Xigui Wu, Ying Li, Dongsheng Hu, Jianfeng Huang, Xiangfeng Lu, Dongfeng Gu
doi : 10.1093/ajcn/nqac159
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 771–779
The causal effects of moderate alcohol consumption on cardiovascular diseases (CVDs) are continuously debated, especially on coronary artery disease (CAD).
Visceral, subcutaneous, and total fat mass accumulation in a prospective cohort of adolescents
Amanda E Staiano, Peter T Katzmarzyk
doi : 10.1093/ajcn/nqac129
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 780–785
Race and sex differences in adolescents’ body fat are demonstrated in cross-sectional cohorts, yet a longitudinal design would better identify patterns of fat distribution over time.
Lipid emulsion rich in n–3 polyunsaturated fatty acids elicits a pro-resolution lipid mediator profile in mouse tissues and in human immune cells
Nazek Noureddine, Ivan Hartling, Paulina Wawrzyniak, Pakeerathan Srikanthan, Phing-How Lou, Eliana Lucchinetti, Stefanie D Krämer, Gerhard Rogler, Michael Zaugg, Martin Hersberger
doi : 10.1093/ajcn/nqac131
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 786–797
Lipid emulsions are a key component of total parenteral nutrition (TPN) and are administered to patients who are unable to ingest their daily required calories orally. Lipid emulsions rich with n–6 (ω-6) PUFAs are known to cause parenteral nutrition–associated liver disease and have inflammatory side effects, whereas n–3 PUFA-rich emulsions have favourable clinical outcomes.
The accuracy of methods for determining the internal length of a nasogastric tube in adult patients: a systematic review
Tim Torsy, Harm H J van Noort, Stephen Taylor, Mats Eriksson, Sofie Verhaeghe, Dimitri Beeckman
doi : 10.1093/ajcn/nqac146
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 798–811
Blind insertion of nasogastric (NG) tubes is performed for several reasons: nutrition and medication administration, gastric aspiration/decompression, and other, diagnostic reasons. Accidental intraesophageal and intestinal placement is common, and increases the risk of serious complications. Therefore, accurate determination of the internal length of the NG tube before placement is considered a prerequisite for achieving correct gastric positioning.
Effects of vitamin C supplementation on gout risk: results from the Physicians’ Health Study II trial
Stephen P Juraschek, J Michael Gaziano, Robert J Glynn, Natalya Gomelskaya, Vadim Y Bubes, Julie E Buring, Robert H Shmerling, Howard D Sesso
doi : 10.1093/ajcn/nqac140
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 812–819
Short-term randomized trials suggest that a 500Â mg/d vitamin C supplement reduces serum urate, whereas observational studies show vitamin E is inversely associated with gout risk.
Prenatal choline supplementation improves biomarkers of maternal docosahexaenoic acid (DHA) status among pregnant participants consuming supplemental DHA: a randomized controlled trial
Kevin C Klatt, Melissa Q McDougall, Olga V Malysheva, Siraphat Taesuwan, Aura (Alex) P Loinard-González, Julie E H Nevins, Kara Beckman, Ruchika Bhawal, Elizabeth Anderson, Sheng Zhang, Erica Bender, Kristina H Jackson, D Janette King, Roger A Dyer, Srisatish Devapatla, Ramesh Vidavalur, J Thomas Brenna, Marie A Caudill
doi : 10.1093/ajcn/nqac147
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 820–832
Dietary methyl donors (e.g., choline) support the activity of the phosphatidylethanolamine N-methyltransferase (PEMT) pathway, which generates phosphatidylcholine (PC) molecules enriched in DHA that are exported from the liver and made available to extrahepatic tissues.
Common errors and pitfalls in observational studies examining the association of medical nutrition therapy with outcomes in critically ill patients
Wolfgang H Hartl
doi : 10.1093/ajcn/nqac142
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Page 833
Reply to WH Hartl
Kensuke Nakamura, Naoki Kanda, Junji Hatakeyama
doi : 10.1093/ajcn/nqac144
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 834–835
A supplemented very low-protein diet could be effective, safe, and feasible in closely monitored patients with advanced CKD
Carmen Antonia Mocanu, Elena Cuiban, Raluca Paul, Daniela Radulescu, Liliana Garneata
doi : 10.1093/ajcn/nqac155
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 836–837,
Reply to Mocanu CA et al
Vincenzo Bellizzi, Simona Signoriello, Paolo Chiodini, Luca De Nicola, ERIKA Study Group
doi : 10.1093/ajcn/nqac156
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 838–839
Could increasing inequalities in energy intake partly explain the increasing prevalence of obesity despite a leveling mean intake?
doi : 10.1093/ajcn/nqac172
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Pages 840–841
Calendar of Events
doi : 10.1093/ajcn/nqac218
The American Journal of Clinical Nutrition, Volume 116, Issue 3, September 2022, Page 842
