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COP27 Climate Change Conference: urgent action needed for Africa and the world: Wealthy nations must step up support for Africa and vulnerable countries in addressing past, present and future impacts of climate change
Laurie Laybourn-Langton, Joy Muhia, Maha El-Adawy, Siaka Sidibé, Chris Zielinski
doi : 10.1093/ajcn/nqac287
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1457–1459
Limited alcohol consumption and lower risk of diabetes: can we believe our own eyes?
Kenneth J Mukamal, Joline W J Beulens
doi : 10.1093/ajcn/nqac258
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1460–1461
Can nonfoodreinforcers sustainably compete with food?
Ashley N Gearhardt
doi : 10.1093/ajcn/nqac242
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1462–1463
COVID Conversations
Andrew O Odegaard
doi : 10.1093/ajcn/nqac268
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1464–1465
Yet another study stirring the debate on saturated fat
Benoît Lamarche
doi : 10.1093/ajcn/nqac270
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1466–1467
Is it caffeine? Coffee consumption and future risk of type 2 diabetes among women with a history of gestational diabetes
Ling-Wei Chen
doi : 10.1093/ajcn/nqac275
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1468–1469
A unified definition of whole-grain foods is needed
David R Jacobs, Jr, Mark A Pereira
doi : 10.1093/ajcn/nqac271
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1470–1471
Unrecognized riboflavin deficiency and evidence for cascading effects on vitamin B-6 status
Martha S Field, Regan L Bailey, Patrick J Stover
doi : 10.1093/ajcn/nqac269
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1472–1473
The omega-3 index in Alzheimer's disease: Ready for prime time?
Hussein N Yassine
doi : 10.1093/ajcn/nqac248
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1474–1475
Does the concept of “ultra-processed foods� help inform dietary guidelines, beyond conventional classification systems? YES
Carlos A Monteiro, Arne Astrup
doi : 10.1093/ajcn/nqac122
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1476–1481
The recommendation to prefer unprocessed/minimally processed foods and freshly made meals instead of ultra-processed foods (following the Nova food classification system) is being increasingly adopted in new official dietary guidelines issued by national governments and international health associations.
Does the concept of “ultra-processed foods� help inform dietary guidelines, beyond conventional classification systems? NO
A Astrup, C A Monteiro
doi : 10.1093/ajcn/nqac123
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1482–1488
The Nova classification of ultra-processed foods (UPFs) rests on poorly defined food processes and the presence of food additives from a chemically heterogeneous group, easily leading to misclassification.
Does the concept of “ultra-processed foods� help inform dietary guidelines, beyond conventional classification systems? Debate consensus
Arne Astrup, Carlos A Monteiro
doi : 10.1093/ajcn/nqac230
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1489–1491
The participants in this debate agree that food processing vitally affects human health, and that the extent of food processing significantly affects diet quality and health outcomes.
Associations of erythrocyte omega-3 fatty acids with cognition, brain imaging and biomarkers in the Alzheimer's disease neuroimaging initiative: cross-sectional and longitudinal retrospective analyses
Laure Rouch, Kelly Virecoulon Giudici, Christelle Cantet, Sophie Guyonnet, Julien Delrieu, Philippe Legrand, Daniel Catheline, Sandrine Andrieu, Michael Weiner, Philipe de Souto Barreto, Bruno Vellas, for the Alzheimer's Disease Neuroimaging Initiative
doi : 10.1093/ajcn/nqac236
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1492–1506
The association between omega-3 (ω-3) PUFAs and cognition, brain imaging and biomarkers is still not fully established.
Moderate alcohol drinking with meals is related to lower incidence of type 2 diabetes
Hao Ma, Xuan Wang, Xiang Li, Yoriko Heianza, Lu Qi
doi : 10.1093/ajcn/nqac207
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1507–1514
Previous studies on alcohol drinking and health largely have ignored the potential impact of the timing of drinking.
A red wine intervention does not modify plasma trimethylamine N-oxide but is associated with broad shifts in the plasma metabolome and gut microbiota composition
Elisa A Haas, Mario J A Saad, Andrey Santos, Nicola Vitulo, Wilson J F Lemos, Jr, Aline M A Martins, Carolina R C Picossi, Desidério Favarato, Renato S Gaspar, Daniéla O Magro, Peter Libby, Francisco R M Laurindo, Protasio L Da Luz, for the WineFlora Study
doi : 10.1093/ajcn/nqac286
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1515–1529
Gut microbiota profiles are closely related to cardiovascular diseases through mechanisms that include the reported deleterious effects of metabolites, such as trimethylamine N-oxide (TMAO), which have been studied as diagnostic and therapeutic targets. Moderate red wine (RW) consumption is reportedly cardioprotective, possibly by affecting the gut microbiota.
Insulinemic potential of diet and risk of total and subtypes of breast cancer among US females
Andrea Romanos-Nanclares, Fred K Tabung, Walter C Willett, Bernard Rosner, Michelle D Holmes, Wendy Y Chen, Rulla M Tamimi, A Heather Eliassen
doi : 10.1093/ajcn/nqac284
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1530–1539
Insulin resistance and hyperinsulinemia play important roles in the progression of multiple chronic disease and conditions. Diet modulates insulin response; however, evidence is limited regarding whether diets with higher insulinemic potential increase the risk of invasive breast cancer.
Association of visceral adipose tissue with postoperative outcome in upper gastrointestinal cancer: a systematic review and meta-analysis
Ryota Matsui, Jun Watanabe, Masahiro Banno, Noriyuki Inaki, Tetsu Fukunaga
doi : 10.1093/ajcn/nqac273
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1540–1552
There is no consensus on the relation between visceral fat mass and long-term postoperative prognosis in patients with upper gastrointestinal (GI) cancer.
Periconceptional folate intake influences DNA methylation at birth based on dietary source in an analysis of pediatric acute lymphoblastic leukemia cases and controls
Eric M Nickels, Shaobo Li, Libby Morimoto, Alice Y Kang, Adam J de Smith, Catherine Metayer, Joseph L Wiemels
doi : 10.1093/ajcn/nqac283
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1553–1564
Periconceptional folate intake is associated with the establishment of DNA methylation in offspring; however, variations in this relation by food sources compared with folic acid supplements are not described. Also, maternal folate intake is associated with decreased risk of pediatric acute lymphoblastic leukemia (ALL), but the mechanism is not known.
One-year longitudinal association between changes in dietary choline or betaine intake and cardiometabolic variables in the PREvención con DIeta MEDiterránea-Plus (PREDIMED-Plus) trial
Laura DÃez-Ricote, Rodrigo San-Cristobal, M José Concejo, Miguel Ã� MartÃnez-González, Dolores Corella, Jordi Salas-Salvadó, Albert Goday, J Alfredo MartÃnez, Ã�ngel M Alonso-Gómez, Julia Wärnberg, Jesús Vioque, Dora Romaguera, José López-Miranda, Ramon Estruch, Francisco J Tinahones, José Lapetra, LluÃs Serra-Majem, Aurora Bueno-Cavanillas, Josep A Tur, Vicente MartÃn Sánchez, Xavier Pintó, José J Gaforio, Pilar MatÃa-MartÃn, Josep Vidal, Sebastián Mas Fontao, Emilio Ros, Zenaida Vázquez-Ruiz, Carolina Ortega-AzorÃn, Jesús F GarcÃa-Gavilán, Mireia Malcampo, Diego MartÃnez-Urbistondo, Lucas Tojal-Sierra, Antonio GarcÃa RodrÃguez, Nuria Gómez-Bellvert, Alice Chaplin, Antonio GarcÃa-RÃos, Rosa M Bernal-López, José M Santos-Lozano, Javier Basterra-Gortari, José V SorlÃ, Michelle Murphy, Griselda Gasulla, VÃctor Micó, Itziar Salaverria-Lete, Estibaliz Goñi Ochandorena, Nancy Babio, Xavier Herraiz, José M Ordovás, Lidia Daimiel
doi : 10.1093/ajcn/nqac255
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1565–1579
We aimed to explore the relation between 1-y changes in dietary intake of choline or betaine and 1-y changes in cardiometabolic and renal function traits within the frame of the PREDIMED (PREvención con DIeta MEDiterránea)-Plus trial.
Bifidobacterium animalis subsp. lactis Bi-07 supports lactose digestion in vitro and in randomized, placebo- and lactase-controlled clinical trials
Pia Rasinkangas, Sofia D Forssten, Maija Marttinen, Alvin Ibarra, Gordana Bothe, Jouni Junnila, Ralf Uebelhack, Yves Donazzolo, Arthur C Ouwehand
doi : 10.1093/ajcn/nqac264
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1580–1594,
The objective was to select a probiotic with high lactase activity and compare it with lactase and placebo in clinical trials.
Homocysteine, folate, and nonalcoholic fatty liver disease: a systematic review with meta-analysis and Mendelian randomization investigation
Shuai Yuan, Jie Chen, Lintao Dan, Ying Xie, Yuhao Sun, Xue Li, Susanna C Larsson
doi : 10.1093/ajcn/nqac285
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1595–1609
Circulating concentrations of homocysteine and folate are inconsistently associated with the risk of nonalcoholic fatty liver disease (NAFLD) in observational studies.
Obesity- and sex-related metabolism of arginine and nitric oxide in adults
Raven A Wierzchowska-McNew, Mariëlle P K J Engelen, John J Thaden, Gabriella A M ten Have, Nicolaas E P Deutz
doi : 10.1093/ajcn/nqac277
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1610–1620
There is growing interest in the supplementation of arginine (Arg) and citrulline (Cit) in obesity due to their potential anti-obesogenic and anti-inflammatory properties. However, there is no consensus on the metabolic changes in Arg kinetics in obesity.
Nutritionally adequate and environmentally respectful diets are possible for different diet groups: an optimized study from the NutriNet-Santé cohort
Emmanuelle Kesse-Guyot, Benjamin Allès, Joséphine Brunin, Hélène Fouillet, Alison Dussiot, François Mariotti, Brigitte Langevin, Florine Berthy, Mathilde Touvier, Chantal Julia, Serge Hercberg, Denis Lairon, Carine Barbier, Christian Couturier, Philippe Pointereau, Julia Baudry
doi : 10.1093/ajcn/nqac253
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1621–1633
Research has shown that vegetarian diets have a low environmental impact, but few studies have examined the environmental impacts and nutritional adequacy of these diets together, even though vegetarian diets can lead to nutritional issues.
Chronic aflatoxin exposure during pregnancy is associated with lower fetal growth trajectories: a prospective cohort from the Butajira Nutrition, Mental Health, and Pregnancy (BUNMAP) Study in rural Ethiopia
Kokeb Tesfamariam, Seifu H Gebreyesus, Carl Lachat, Giles T Hanley-Cook, Meselech Roro, Yalemwork G Mengistu, Bilal S Endris, Tefera Belachew, Patrick Kolsteren, Sarah De Saeger, Marthe De Boevre, Alemayehu Argaw
doi : 10.1093/ajcn/nqac280
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1634–1641
Aflatoxins are toxic secondary metabolites produced by Aspergillus fungi, which are ubiquitously present in the food supplies of low- and middle-income countries. Studies of maternal aflatoxin exposure and fetal outcomes are mainly focused on size at birth and the effect on intrauterine fetal growth has not been assessed.
Reducing relative food reinforcement of infants using a music enrichment program: a randomized, controlled trial
Kai Ling Kong, Rina D Eiden, Katherine S Morris, Rocco A Paluch, Katelyn A Carr, Leonard H Epstein
doi : 10.1093/ajcn/nqac209
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1642–1653
Food reinforcement or one's motivation to eat may be established early in life; it might not be the food reinforcement per se that drives weight gain, but rather the imbalance between food and nonfood reinforcement.
Infant consumption of microRNA miR-375 in human milk lipids is associated with protection from atopy
Steven D Hicks, Ramin Beheshti, Desirae Chandran, Kaitlyn Warren, Alexandra Confair
doi : 10.1093/ajcn/nqac266
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1654–1662
Human milk is thought to reduce infant atopy risk. The biologic mechanism for this protective effect is not fully understood.
The effects of 9 months of formulated whole-egg or milk powder food products as meal or snack replacements on executive function in preadolescents: A randomized, placebo-controlled trial
Patrick J O'Connor, Xianyan Chen, Lauren M Coheley, Mengyun Yu, Emma M Laing, Assaf Oshri, Alicia Marand, Julia Lance, Kirk Kealey, Richard D Lewis
doi : 10.1093/ajcn/nqac281
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1663–1671
Elevated brain choline is associated with better executive functions in preadolescents. Manipulating dietary choline prospectively in preadolescents using egg supplementation could improve executive functions via effects on brain cellular and neurotransmitter functions.
Long-term diet and risk of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection and Coronavirus Disease 2019 (COVID-19) severity
Yiyang Yue, Wenjie Ma, Emma K Accorsi, Ming Ding, Frank Hu, Walter C Willett, Andrew T Chan, Qi Sun, Janet Rich-Edwards, Stephanie A Smith-Warner, Shilpa N Bhupathiraju
doi : 10.1093/ajcn/nqac219
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1672–1681
The role of diet on Coronavirus Disease 2019 (COVID-19) is emerging. We investigated the association between usual diet before the onset of the pandemic and risk and severity of subsequent SARS-CoV-2 infection.
Saturated fat from dairy sources is associated with lower cardiometabolic risk in the Framingham Offspring Study
Mengjie Yuan, Martha R Singer, Richard T Pickering, Lynn L Moore
doi : 10.1093/ajcn/nqac224
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1682–1692
Current dietary guidance recommends limiting intakes of saturated fats, but most fails to consider that saturated fats from different food sources may have different health effects.
Habitual coffee consumption and subsequent risk of type 2 diabetes in individuals with a history of gestational diabetes – a prospective study
Jiaxi Yang, Deirdre K Tobias, Shanshan Li, Shilpa N Bhupathiraju, Sylvia H Ley, Stefanie N Hinkle, Frank Qian, Zhangling Chen, Yeyi Zhu, Wei Bao, Jorge E Chavarro, Frank B Hu, Cuilin Zhang
doi : 10.1093/ajcn/nqac241
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1693–1703
Females with a history of gestational diabetes mellitus (GDM) are at higher risk of developing type 2 diabetes mellitus (T2D) later in life.
Whole-grain food intake among US adults, based on different definitions of whole-grain foods, NHANES 2003–2018
Mengxi Du, Dariush Mozaffarian, John B Wong, Jennifer L Pomeranz, Parke Wilde, Fang Fang Zhang
doi : 10.1093/ajcn/nqac267
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1704–1714
Whole-grain (WG) foods are defined by the Dietary Guidelines for Americans (DGA), FDA, AHA, American Association of Cereal Chemists International (AACCI), and Whole Grains Council (WGC) in different ways with diverse focuses on grain components only, whole foods, or nutrient contents.
Habitual intake of dietary methylglyoxal is associated with less low-grade inflammation: the Maastricht Study
Kim Maasen, Simone J P M Eussen, Pieter C Dagnelie, Alfons J H M Houben, Carroll A B Webers, Miranda T Schram, Tos T J M Berendschot, Coen D A Stehouwer, Antoon Opperhuizen, Marleen M J van Greevenbroek, Casper G Schalkwijk
doi : 10.1093/ajcn/nqac195
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1715–1728
Dicarbonyls are major reactive precursors of advanced glycation endproducts (AGEs). Dicarbonyls are formed endogenously and also during food processing. Circulating dicarbonyls and AGEs are associated with inflammation and microvascular complications of diabetes, but for dicarbonyls from the diet these associations are currently unknown.
Physical activity and individual plasma phospholipid SFAs in pregnancy: a longitudinal study in a multiracial/multiethnic cohort in the United States
Xinyue Liu, Liwei Chen, Zhe Fei, Sifang K Zhao, Yeyi Zhu, Tong Xia, Jin Dai, Mohammad L Rahman, Jing Wu, Natalie L Weir, Michael Y Tsai, Cuilin Zhang
doi : 10.1093/ajcn/nqac250
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1729–1737
Circulating individual SFAs in pregnant females are critical for maternal and fetal health. However, research on identifying their modifiable factors is limited.
Overall diet quality and proinflammatory diet in relation to risk of obstructive sleep apnea in 3 prospective US cohorts
Yue Liu, Fred K Tabung, Meir J Stampfer, Susan Redline, Tianyi Huang
doi : 10.1093/ajcn/nqac257
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1738–1747
Inflammation-related mechanisms may be important in the development of obstructive sleep apnea (OSA), and diet plays a crucial role in modulating inflammation. Current epidemiologic evidence for the associations between dietary patterns and OSA risk is limited to cross-sectional studies.
Greater adherence to the 2019 Canada's Food Guide recommendations on healthy food choices reduces the risk of cardiovascular disease in adults: a prospective analysis of UK Biobank data
Didier Brassard, Hasanga D Manikpurage, Sébastien Thériault, Benoît J Arsenault, Benoît Lamarche
doi : 10.1093/ajcn/nqac256
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1748–1758
Canada's Food Guide (CFG) was profoundly revised in 2019, but the extent to which adherence to recommendations on healthy food choices reduces the risk of cardiovascular disease (CVD) is unknown.
Association of omega-3 and omega-6 fatty acid intake with leukocyte telomere length in US males
Bojung Seo, Keming Yang, Ka Kahe, Abrar A Qureshi, Andrew T Chan, Immaculata De Vivo, Eunyoung Cho, Edward L Giovannucci, Hongmei Nan
doi : 10.1093/ajcn/nqac263
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1759–1766
Omega-3 (n–3) and omega-6 (n–6) fatty acids may contribute to oxidative stress and inflammation, which are related to telomere shortening. Evidence supporting an association between intake of n–3 or n–6 fatty acids and leukocyte telomere length (LTL) in males has been limited.
Vitamin B-6 and riboflavin, their metabolic interaction, and relationship with MTHFR genotype in adults aged 18–102 years
Harry Jarrett, Helene McNulty, Catherine F Hughes, Kristina Pentieva, J J Strain, Adrian McCann, Liadhan McAnena, Conal Cunningham, Anne M Molloy, Albert Flynn ... Show more
doi : 10.1093/ajcn/nqac240
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1767–1778
The generation of the active form of vitamin B-6, pyridoxal 5′-phosphate (PLP), in tissues is dependent upon riboflavin as flavin mononucleotide, but whether this interaction is important for maintaining vitamin B-6 status is unclear.
Top sources and trends in consumption of total energy and energy from solid fats and added sugars among youth aged 2–18 years: United States 2009–2018
Edwina A Wambogo, Lauren E O'Connor, Marissa M Shams-White, Kirsten A Herrick, Jill Reedy
doi : 10.1093/ajcn/nqac238
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1779–1789
High energy intake from non–nutrient-dense sources correlates with poorer diet quality.
The impact of almonds and almond processing on gastrointestinal physiology, luminal microbiology, and gastrointestinal symptoms: a randomized controlled trial and mastication study
Alice C Creedon, Eirini Dimidi, Estella S Hung, Megan Rossi, Christopher Probert, Terri Grassby, Jesus Miguens-Blanco, Julian R Marchesi, S Mark Scott, Sarah E Berry, Kevin Whelan
doi : 10.1093/ajcn/nqac265
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1790–1804
Almonds contain lipid, fiber, and polyphenols and possess physicochemical properties that affect nutrient bioaccessibility, which are hypothesized to affect gut physiology and microbiota.
Novel lipid emulsion for total parenteral nutrition based on 18-carbon n–3 fatty acids elicits a superior immunometabolic phenotype in a murine model compared with standard lipid emulsions
Eliana Lucchinetti, Phing-How Lou, Gregory Holtzhauer, Nazek Noureddine, Paulina Wawrzyniak, Ivan Hartling, Megan Lee, Erin Strachan, Xavier Clemente-Casares, Sue Tsai, Gerhard Rogler, Stefanie D Krämer, Martin Hersberger, Michael Zaugg
doi : 10.1093/ajcn/nqac272
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1805–1819
While lipid emulsions in modern formulations for total parenteral nutrition (TPN) provide essential fatty acids and dense calories, they also promote inflammation and immunometabolic disruptions.
Unprocessed red meat in the dietary treatment of obesity: a randomized controlled trial of beef supplementation during weight maintenance after successful weight loss
Faidon Magkos, Sidse I Rasmussen, Mads F Hjorth, Sarah Asping, Maria I Rosenkrans, Anders M Sjödin, Arne V Astrup, Nina R W Geiker
doi : 10.1093/ajcn/nqac152
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1820–1830
Consumption of unprocessed red meat in randomized trials has no adverse effects on cardiovascular risk factors and body weight, but its physiological effects during weight loss maintenance are not known.
Gut microbiota and acylcarnitine metabolites connect the beneficial association between equol and adiposity in adults: a prospective cohort study
Yan-yan Wu, Wanglong Gou, Yan Yan, Chun-ying Liu, Yingdi Yang, Danyu Chen, Keliang Xie, Zengliang Jiang, Yuanqing Fu, Hui-lian Zhu, Ju-Sheng Zheng, Yu-ming Chen
doi : 10.1093/ajcn/nqac252
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1831–1841
Many studies have investigated the effects of soy isoflavones on weight control, but few have focused on the role of equol, a gut-derived metabolite of daidzein with greater bioavailability than other soy isoflavones.
The association between TMAO, CMPF, and clinical outcomes in advanced chronic kidney disease: results from the European QUALity (EQUAL) Study
Lu Dai, Ziad A Massy, Peter Stenvinkel, Nicholas C Chesnaye, Islam Amine Larabi, Jean Claude Alvarez, Fergus J Caskey, Claudia Torino, Gaetana Porto, Maciej Szymczak, Magdalena Krajewska, Christiane Drechsler, Christoph Wanner, Kitty J Jager, Friedo W Dekker, Pieter Evenepoel, Marie Evans, the EQUAL Study Investigators
doi : 10.1093/ajcn/nqac278
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1842–1851
Trimethylamine N-oxide (TMAO), a metabolite from red meat and fish consumption, plays a role in promoting cardiovascular events. However, data regarding TMAO and its impact on clinical outcomes are inconclusive, possibly due to its undetermined dietary source.
Associations between folic acid supplement use and folate status biomarkers in the first and third trimesters of pregnancy in the Maternal–Infant Research on Environmental Chemicals (MIREC) Pregnancy Cohort Study
Marisa A Patti, Joseph M Braun, Tye E Arbuckle, Amanda J MacFarlane
doi : 10.1093/ajcn/nqac235
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1852–1863
Achieving optimal folate status during early gestation reduces the risk of neural tube defects (NTDs). While inadequate folate intake remains a concern, it is becoming increasingly common for individuals to consume higher than recommended doses of folic acid (FA) with minimal additional benefit.
Effects of prenatal nutritional supplements on gestational weight gain in low- and middle-income countries: a meta-analysis of individual participant data
Enju Liu, Dongqing Wang, Anne M Darling, Nandita Perumal, Molin Wang, Tahmeed Ahmed, Parul Christian, Kathryn G Dewey, Gilberto Kac, Stephen Kennedy, Vishak Subramoney, Brittany Briggs, Wafaie W Fawzi, members of the GWG Pooling Project Consortium
doi : 10.1093/ajcn/nqac259
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1864–1876
Gestational weight gain (GWG) below or above the Institute of Medicine (IOM) recommendations has been associated with adverse perinatal outcomes. Few studies have examined the effect of prenatal nutrient supplementations on GWG in low- and middle-income countries (LMICs).
Research gaps and opportunities in precision nutrition: an NIH workshop report
Bruce Y Lee, José M Ordovás, Elizabeth J Parks, Cheryl A M Anderson, Albert-László Barabási, Steven K Clinton, Kayla de la Haye, Valerie B Duffy, Paul W Franks, Elizabeth M Ginexi, Kristian J Hammond, Erin C Hanlon, Michael Hittle, Emily Ho, Abigail L Horn, Richard S Isaacson, Patricia L Mabry, Susan Malone, Corby K Martin, Josiemer Mattei, Simin Nikbin Meydani, Lorene M Nelson, Marian L Neuhouser, Brendan Parent, Nicolaas P Pronk, Helen M Roche, Suchi Saria, Frank A J L Scheer, Eran Segal, Mary Ann Sevick, Tim D Spector, Linda Van Horn, Krista A Varady, Venkata Saroja Voruganti, Marie F Martinez
doi : 10.1093/ajcn/nqac237
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1877–1900
Precision nutrition is an emerging concept that aims to develop nutrition recommendations tailored to different people's circumstances and biological characteristics.
The A, B, C, D's of dietary trials
Heidi M Staudacher, Tetyana Rocks, Felice N Jacka
doi : 10.1093/ajcn/nqac274
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1901–1902
Reply to H Staudacher et al
Jessica Bayes, Janet Schloss, David Sibbritt
doi : 10.1093/ajcn/nqac276
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Pages 1903–1904
Correction to: Gardner et al. Effect of a ketogenic diet versus Mediterranean diet on glycated hemoglobin in individuals with prediabetes and type 2 diabetes mellitus: The interventional Keto-Med randomized crossover trial
doi : 10.1093/ajcn/nqac279
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Page 1904
Correction to: Perumal et al. Impact of scaling up prenatal nutrition interventions on human capital outcomes in low- and middle-income countries: a modeling analysis
doi : 10.1093/ajcn/nqac282
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Page 1904
Correction to: Bettina Hieronimus, Kimber L Stanhope, RE: Current WHO recommendation to reduce free sugar intake from all sources to below 10% of daily energy intake for supporting overall health is not well supported by available evidence. Am J Clin Nutr 2022;116:1187
doi : 10.1093/ajcn/nqac289
The American Journal of Clinical Nutrition, Volume 116, Issue 6, December 2022, Page 1904
