دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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Effect of environmental enrichment on aggression and the expression of brain-derived neurotrophic factor transcript variants in group-housed male mice
Muhammad S. Aldhshan , Tooru M. MizunoMuhammad S. Aldhshan , Tooru M. Mizuno
doi : 10.1016/j.bbr.2022.113986
Volume 433, 5 September 2022, 113986
Social and environmental factors influence behavior via modulation of brain physiological functions. Environmental enrichment (EE) is an animal housing technique that provides complex sensory, motor, and social stimulation, leading to modifications in the innate aggressiveness in group-housed laboratory mice.
Adipose-derived mesenchymal stem cells reduced transient cerebral ischemia injury by modulation of inflammatory factors and AMPK signaling
Mina Ranjbaran a,b, Reyhaneh Vali b, Zahra Yaghoobi b, Fardin Sehati b, Vida Jashn a,b, Sevda Mahdipour Kolur a,b, Fariba Akhondzadeh b, Ghorbangol Ashabi
doi : 10.1016/j.bbr.2022.114001
Volume 433, 5 September 2022, 114001
Stem cell-based treatments have been recommended as a feasible therapy for stroke victims due to their potential for angiogenesis, neurogenesis, and synaptic plasticity.
Post-learning caffeine administration improves ‘what-when’ and ‘what-where’ components of episodic-like memory in rats
Ana Luiza Alves Dias a, Adriana Maria Fernandes de Oliveira Golzio b, Bruno Henrique de Lima Santos a, Mirian Graciela da Silva Stiebbe Salvadori c, S �ocrates Golzio dos Santos d, Marcelo Sobral da Silva d, Reinaldo N �obrega de Almeida e, Flavio Freitas Barbosa
doi : 10.1016/j.bbr.2022.113982
Volume 433, 5 September 2022, 113982
Episodic-like memory (ELM) consists in the capacity of nonhuman animals to remember ‘where’ and ‘when’ a specific episode occurred (‘what’). Previous studies have showed that Wistar rats can form an ELM, but not after a 24 h retention delay.
Altered resting-state functional connectivity of medial frontal cortex in overweight individuals: Link to food-specific intentional inhibition and weight gain
Liu Xinyuan a,b, Chen Ximei a,b, Li Qingqing a,b, Xiang Guangcan a,b, Li Wei a,b, Xiao Mingyue a,b, Du Xiaoli a,b, Song Shiqing a,b, Liu Yong a,b, Chen Hong
doi : 10.1016/j.bbr.2022.114003
Volume 433, 5 September 2022, 114003
Numerous findings from functional neuroimaging research suggest that overweight may be associated with alterations in reactive inhibition. However, there is a dearth of research investigating the functional connectivity that mediates intentional inhibition in overweight individuals.
A 5-HT6R agonist alleviates cognitive dysfunction after traumatic brain injury in rats by increasing BDNF expression
Fu-Yong Ou a,b, Ya-Lei Ning c,d, Nan Yang c, Xing Chen c, Yan Peng c, Yan Zhao c,d, Ping Li c,d, Yuan-Guo Zhou c,d,*, Yan Liu
doi : 10.1016/j.bbr.2022.113997
Volume 433, 5 September 2022, 113997
Effective treatment for cognitive dysfunction after traumatic brain injury (TBI) is lacking in clinical practice. Increased brain-derived neurotrophic factor (BDNF) expression in cognitive circuits can significantly alleviate cognitive dysfunction in animal models of TBI.
Altered dynamic amplitude of low-frequency fluctuations in patients with postpartum depression
Fanghui Dong a,b,1, Zhongsheng Zhang b,1, Tongpeng Chu b,1, Kaili Che b, Yuna Li b, Qun Gai b, Yinghong Shi b, Heng Ma b, Feng Zhao c, Ning Mao b,*, Haizhu Xie
doi : 10.1016/j.bbr.2022.113980
Volume 433, 5 September 2022, 113980
Postpartum depression (PPD) is a common mood disorder with increasing incidence year by year. However, the dynamic changes in local neural activity of patients with PPD remain unclear. In this study, we utilized the dynamic amplitude of low-frequency fluctuation (dALFF) method to investigate the abnormal temporal variability of local neural activity and its potential correlation with clinical severity in PPD.
S-ketamine administration in pregnant mice induces ADHD- and depression-like behaviors in offspring mice
Li-Min Zhang a,*,1, Na-Na Liu a,b,1, Lu Cao c, Yue Xin a,d, Dong-Xue Zhang a,e, Yang Bai a, Wei-Chao Zheng a, Xin-Ying Bi f, Bao-Heng Xing g, Wei Zhang
doi : 10.1016/j.bbr.2022.113996
Volume 433, 5 September 2022, 113996
Anesthesia and psychotropic drugs in pregnant women may cause long-term effects on the brain development of unborn babies. The authors set out to investigate the neurotoxicity of S-ketamine, which possesses anesthetic and antidepressant effects and may cause attention deficit hyperactivity disorder (ADHD)- and depression-like behaviors in offspring mice.
HDAC3 of dorsal hippocampus induces postoperative cognitive dysfunction in aged mice
Li Yang a,b,1, Jing-Ru Hao a,1, Yin Gao a,c,1, Xiu Yang a, Xiao-Ran Shen a, Hu-Yi Wang a, Nan Sun a, Can Gao
doi : 10.1016/j.bbr.2022.114002
Volume 433, 5 September 2022, 114002
Postoperative cognitive dysfunction (POCD) affects a substantial number of aged individuals.
Resting-state neural signal variability in women with depressive disorders
Sally Pessin a, Erin C. Walsh b, Roxanne M. Hoks c, Rasmus M. Birn d, Heather C. Abercrombie c, Carissa L. Philippi
doi : 10.1016/j.bbr.2022.113999
Volume 433, 5 September 2022, 113999
Aberrant activity and connectivity in default mode (DMN), frontoparietal (FPN), and salience (SN) network regions is well-documented in depression.
Intermittent theta burst stimulation ameliorates cognitive impairment and hippocampal gliosis in the Streptozotocin-induced model of Alzheimer's disease
Jelena Stanojevic a,b,*, Milorad Dragic c, Ivana Stevanovic b, Tihomir Ilic b, Ivana Stojanovic a, Milica Zeljkovic c, Milica Ninkovic
doi : 10.1016/j.bbr.2022.113984
Volume 433, 5 September 2022, 113984
Intracerebroventricularly (icv) injected streptozotocin (STZ) model of Alzheimer's disease (AD) is used to explore the effect of intermittent theta burst stimulation (iTBS) on astrocyte and microglia reactivity in selectively vulnerable brain regions and answer the question whether these changes are in the context of cognitive capacity.
Differential effects of lipopolysaccharide on cognition, corticosterone and cytokines in socially-housed vs isolated male rats
Brittney Russell a,c,1, Kelly M. Hrelja a,*,1, Wendy K. Adams a,c, Fiona D. Zeeb a,c, Matthew D. Taves a,b,c, Sukhbir Kaur a,c, Kiran K. Soma a,b,c, Catharine A. Winstanley
doi : 10.1016/j.bbr.2022.114000
Volume 433, 5 September 2022, 114000
Social isolation is an established risk factor for mental illness and impaired immune function. Evidence suggests that neuroinflammatory processes contribute to mental illness, possibly via cytokine-induced modulation of neural activity.
Fluoxetine protects against inflammation and promotes autophagy in mice model of post-traumatic stress disorder
Chengjian Lou a,1, Marong Fang b,c,1, Shan Ye d,1, Zhanglu Fang d, Nashwa Amin b,c,e, Yili Chen
doi : 10.1016/j.bbr.2022.114004
Volume 433, 5 September 2022, 114004
Post-traumatic stress disorder is a major public health problem due to its frequency, chronicity, and disability that impact daily life. Studies have evidenced that the activation/inhibition of autophagy and excessive activation of microglia have a relationship with PTSD.
Rosmarinic acid relieves LPS-induced sickness and depressive-like behaviors in mice by activating the BDNF/Nrf2 signaling and autophagy pathway
Yi Yu 1, Ye Li 1, Keming Qi, Wei Xu, Yicong Wei
doi : 10.1016/j.bbr.2022.114006
Volume 433, 5 September 2022, 114006
Neuroinflammation is one of the main causes of sickness and depressive-like behavior. Rosmarinic acid (RA) has been shown to have a significant anti-neuroinflammatory effect. However, the protective effects and the underlying mechanism of RA on sickness and depressive-like behavior under conditions of neuroinflammation are still unclear.
Testosterone treatment restores vestibular function by enhancing neuronal survival in an experimental closed-head repetitive mild traumatic brain injury model
Eileen M. Foecking a,d,i,*, Arthur B. Segismundo c, Krista M. Lotesto d, Edward J. Westfall e, Alyssa J. Bolduan e, Tony K. Peter e, Douglas G. Wallace f, Dorothy A. Kozlowski g, Evan B. Stubbs Jr. b,e, Sam J. Marzo e, Susanna C. Byram
doi : 10.1016/j.bbr.2022.113998
Volume 433, 5 September 2022, 113998
Repetitive mild traumatic brain injury (rmTBI) results in a myriad of symptoms, including vestibular impairment. The mechanisms underlying vestibular dysfunction in rmTBI patients remain poorly understood. Concomitantly, acute hypogonadism occurs following TBI and can persist chronically in many patients.
Prenatal chronic stress impairs the learning and memory ability via inhibition of the NO/cGMP/PKG pathway in the Hippocampus of offspring
Youjuan Fu a,b, Hongya Liu a,b, Ling He c, Shuqin Ma c, Xiaohui Chen a,b, Kai Wang a,b, Feng Zhao a,b, Faqiu Qi a,b, Suzhen Guan a,b,d,*, Zhihong Liu
doi : 10.1016/j.bbr.2022.114009
Volume 433, 5 September 2022, 114009
Numerous clinical and animal studies have found that antenatal chronic stress can lead to pathological changes the hippocampal development from embryos to adult, but the mechanisms are not well understood.
Exercise hormone irisin prevents physical inactivity-induced cognitive decline in mice
Jonghyuk Park a, Jimmy Kim a, Toshio Mikami
doi : 10.1016/j.bbr.2022.114008
Volume 433, 5 September 2022, 114008
We previously reported that physical inactivity (PI) induces cognitive decline and depressive states, which were ameliorated by regular exercise. However, the mechanism underlying the preventive effect of exercise remains unelucidated.
The role of triggering receptor expressed on myeloid cells 2 in Parkinson’s disease and other neurodegenerative disorders
Hannah Schwarz a, Sarah B ̈assler b, Denise Balta b, Eileen Socher a, Friederike Zunke b,*, Philipp Arnold
doi : 10.1016/j.bbr.2022.113977
Volume 433, 5 September 2022, 113977
Parkinson’s disease (PD) is a progressive neurological disorder marked by cardinal clinical symptoms such as rigor, tremor, and akinesia.
