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Coronary Calcium Scoring Improves Risk Prediction in Patients With Suspected Obstructive Coronary Artery Disease
Simon Winther, MD, P HD, a,b Samuel E. Schmidt, MS C, PHD, c Borek Foldyna, MD, d Thomas Mayrhofer, PHD, d,e Laust D. Rasmussen, MD,a,b Jonathan N. Dahl, MD,a,b Udo Hoffmann, MD, MPH,d Pamela S. Douglas, MD,f Juhani Knuuti, MD, P HD, g,h Morten Bøttcher, MD, P HD
doi : 10.1016/j.jacc.2022.08.805
Volume 80, Issue 21, 22 November 2022, Pages 1965-1977
In patients with suspected obstructive coronary artery disease (CAD), the risk factor–weighted clinical likelihood (RF-CL) model and the coronary artery calcium score–weighted clinical likelihood (CACS-CL) model improves the identification of obstructive CAD compared with basic pretest probability (PTP) models.
Power of Zero as Gatekeeper for Stable Chest Pain Patients: Minimizing Losses and Maximizing Gains∗
Khurram Nasir, MD, MPH, MSC ,a,b Safi U. Khan, MD, MS
doi : 10.1016/j.jacc.2022.09.024
Volume 80, Issue 21, 22 November 2022, Pages 1978-1980
Prognostic Prediction of Genotype vs Phenotype in Genetic Cardiomyopathies
Alessia Paldino, MD, a, * Matteo Dal Ferro, MD, a, * Davide Stolfo, MD,a Ilaria Gandin, PHD, b Kristen Medo, MS, c Sharon Graw, P HD, c Marta Gigli, MD, a Giulia Gagno, MD, a Denise Zaffalon, MD, a Matteo Castrichini, MD,a,c Marco Masè, MD,a Antonio Cannatà , MD,d Francesca Brun, MD,a Garrett Storm, BS, c Giovanni Maria Severini, PHD, e Stefania Lenarduzzi, MS C,e Giorgia Girotto, P HD, e,f Paolo Gasparini, MD, PH D, e,f Francesca Bortolotti, PHD, g Mauro Giacca, MD, PHD, d,g Serena Zacchigna, MD, PHD, f,g Marco Merlo, MD, a Matthew R.G. Taylor, MD, PH D, c Luisa Mestroni, MD, c Gianfranco Sinagra, MD
doi : 10.1016/j.jacc.2022.08.804
Volume 80, Issue 21, 22 November 2022, Pages 1981-1994
Diverse genetic backgrounds often lead to phenotypic heterogeneity in cardiomyopathies (CMPs). Previous genotype-phenotype studies have primarily focused on the analysis of a single phenotype, and the diagnostic and prognostic features of the CMP genotype across different phenotypic expressions remain poorly understood.
Genotype-Based Risk Stratification Can Outperform Phenotype-Based Practice for Inherited Cardiomyopathies: Not All Paths Are Equal∗
Cynthia A. James, PH D, CGC, Alessio Gasperetti, MD
doi : 10.1016/j.jacc.2022.09.018
Volume 80, Issue 21, 22 November 2022, Pages 1995-1997
Equivalent Impact of Elevated Lipoprotein(a) and Familial Hypercholesterolemia in Patients With Atherosclerotic Cardiovascular Disease
Berit Storgaard Hedegaard, RN,a,b,c Christian Sørensen Bork, MD, P HD, d Morten Kaltoft, MD, PH D, c,e,f Ib Christian Klausen, MD, DMSC ,a Erik Berg Schmidt, MD, DMS C,b Pia Rørbæk Kamstrup, MD, PHD, c,e Anne Langsted, MD, PHD, c,e,f Børge Grønne Nordestgaard, MD, DMS C
doi : 10.1016/j.jacc.2022.09.021
Volume 80, Issue 21, 22 November 2022, Pages 1998-2010
Lipoprotein(a) and LDL-C: The Relevance of Equivalence
Pamela B. Morris, MD, a Jagat Narula, MD, PHD, b Sotirios Tsimikas, MD
doi : 10.1016/j.jacc.2022.09.026
Volume 80, Issue 21, 22 November 2022, Pages 2011-2013
Outcomes of Pregnancy in Women With Bioprosthetic Heart Valves With or Without Valve Dysfunction
Barbara Wichert-Schmitt, MD,a,b Jasmine Grewal, MD,c A. Kinga Malinowski, MD, d Birgit Pfaller, MD,a,e Katie L. Losenno, MD, a Marla C. Kiess, MD, c Jack M. Colman, MD, a Wendy Tsang, MD, a Jennifer Mason, RN, a Samuel C. Siu, MD, f Candice K. Silversides, MD
doi : 10.1016/j.jacc.2022.09.019
Volume 80, Issue 21, 22 November 2022, Pages 2014-2024
Impact of Bioprosthetic Valve Dysfunction on Pregnancy Outcomes: Left Side, Right Side, and Beyond
Deirdre J. Mattina, MD,a,b Katharine French, MD,c,d Athena Poppas, MD
doi : 10.1016/j.jacc.2022.09.023
Volume 80, Issue 21, 22 November 2022, Pages 2025-2027
Randomized Trials of Percutaneous Microaxial Flow Pump Devices: JACC State-of-the-Art Review
Mohit Pahuja, MD,a Adam Johnson, MD,b Ryan Kabir, MD, c Sukhdeep Bhogal, MD, c Jason P. Wermers, MS, c Nelson L. Bernardo, MD, c Itsik Ben-Dor, MD,c Hayder Hashim, MD,c Lowell F. Satler, MD,c Farooq H. Sheikh, MD, c Ron Waksman, MD
doi : 10.1016/j.jacc.2022.08.807
Volume 80, Issue 21, 22 November 2022, Pages 2028-2049
The use of mechanical circulatory support devices in cardiovascular practice has risen exponentially over the past decade. These devices are currently used for hemodynamic support in patients with cardiogenic shock, high-risk percutaneous coronary intervention, left ventricular unloading, protection of kidneys, and right ventricular failure.
Gender and Racial/Ethnic Disparities in Award Distribution by Major Cardiovascular Societies From 2000 to 2021
Kinza Iqbal, MBBS, a Ashish Kumar, MD,b Sawai Singh Rathore, MBBS, c Eisha Farid, MBBS, a Ali Ishaque, MBBS,a Hadiya Afzal, MBBS, a Maha Zahid, MBBS,a Purvi Parwani, MD, d Erin D. Michos, MD, MHS, e Martha Gulati, MD, MS
doi : 10.1016/j.jacc.2022.09.016
Volume 80, Issue 21, 22 November 2022, Pages 2050-2053
National Trends in TAVR and SAVR for Patients With Severe Isolated Aortic Stenosis
Toishi Sharma, MD Anand M. Krishnan, MD Rony Lahoud, MD Marek Polomsky, MD *Harold L. Dauerman, MD
doi : 10.1016/j.jacc.2022.08.787
Volume 80, Issue 21, 22 November 2022, Pages 2054-2056
Carotid Plaque Burden Is a Stronger Predictor of Cardiovascular Risk Than IMT
*J. David Spence, MD
doi : 10.1016/j.jacc.2022.08.806
Volume 80, Issue 21, 22 November 2022, Page e191
Reply: Carotid Plaque Burden Is a Stronger Predictor of Cardiovascular Risk Than IMT
Josep Iglesies-Grau, MD Valentin Fuster, MD, PhD *Rodrigo Fernandez-Jimenez, MD, PhD
doi : 10.1016/j.jacc.2022.09.020
Volume 80, Issue 21, 22 November 2022, Page e193
