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Editorial introductions.
doi : 10.1097/BOR.0000000000000920
Volume 35(1) pgs. v-vi,1-60 January 2023
2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria sets for three types of antineutrophilic cytoplasmic antibody-associated vasculitis.
Yazici, Hasan a; Tascilar, Koray b; Yazici, Yusuf c
doi : 10.1097/BOR.0000000000000916
A critique of the recently published classification criteria for three main types of antineutrophilic cytoplasmic antibody (ANCA)-associated vasculitis. Recent findings: An ACR and EULAR joint task force recently published classification criteria for three main types of ANCA-associated vasculitis.
A cursed goodbye kiss from severe acute respiratory syndrome-coronavirus-2 to its pediatric hosts: multisystem inflammatory syndrome in children.
Haslak, Fatih; Gunalp, Aybuke; Kasapcopur, Ozgur
doi : 10.1097/BOR.0000000000000910
We aimed to summarize a novel disease called multisystem inflammatory syndrome in children (MIS-C), which develops several weeks after a severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) illness.
Uveitis in Behcet disease - an update.
Tugal-Tutkun, Ilknur a,b
doi : 10.1097/BOR.0000000000000911
Uveitis is a major manifestation of Behcet disease (BD) and potentially has a high morbidity. This article reviews recently published data on BD uveitis. Recent findings: A set of classification criteria and a diagnostic algorithm have been developed for BD uveitis.
Regulatory T cells and systemic vasculitis.
Mirouse, Adrien a,b; Cacoub, Patrice a,b; Saadoun, David a,b
doi : 10.1097/BOR.0000000000000915
Emerging data suggest that regulatory T-cells (Treg) alterations play a major role in systemic vasculitis pathophysiology. We performed a systematic review of recent advances in the role of Treg and interleukin (IL)-10 in the pathogenesis and treatment of systemic vasculitis, including giant cell arteritis (GCA), Takayasu arteritis, Behcet's disease, antineutrophil cytoplasm antibodies (ANCA) associated vasculitis (AAV), and cryoglobulinemia associated vasculitis.
The complement system in antineutrophil cytoplasmic antibody-associated vasculitis: pathogenic player and therapeutic target.
Mazzariol, Martina a,b; Manenti, Lucio c; Vaglio, Augusto b,d
doi : 10.1097/BOR.0000000000000914
The purpose of this review is to discuss the role of the complement system in the pathogenesis of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) as well as the employment of complement inhibitors in AAV treatment.
Osteoarthritis gene therapy in 2022.
Evans, Christopher H. a; Ghivizzani, Steven C. b; Robbins, Paul D. c
doi : 10.1097/BOR.0000000000000918
To assess the present status of gene therapy for osteoarthritis (OA). Recent findings: An expanding list of cDNAs show therapeutic activity when introduced into the joints of animals with experimental models of OA.
Advances in osteoarthritis imaging.
Chalian, Majid a; Roemer, Frank W. b,c; Guermazi, Ali c,d
doi : 10.1097/BOR.0000000000000917
Imaging plays a pivotal role for diagnosis, follow-up and stratification of osteoarthritis patients in clinical trials and research. We aim to present an overview of currently available and emerging imaging techniques for osteoarthritis assessment and provide insight into relevant benefits and pitfalls of the different modalities.
The impact of omics research on our understanding of osteoarthritis and future treatments.
Beier, Frank
doi : 10.1097/BOR.0000000000000919
To review recent studies using 'Omics' approaches (genomics, proteomics, metabolomics, single cell analyses) in patient populations and animal models of osteoarthritis (OA), with the goal of identifying disease-modifying mechanisms that could serve as therapeutic and diagnostic targets.
