Jeffrey R. Curtis, Sindhu R. Johnson, Donald D. Anthony, Reuben J. Arasaratnam, Lindsey R. Baden, Anne R. Bass, Cassandra Calabrese, Ellen M. Gravallese, Rafael Harpaz, Andrew Kroger, Rebecca E. Sadun, Amy S. Turner, Eleanor Anderson Williams, Ted R. Mikuls
doi : 10.1002/art.42372
To provide guidance to rheumatology providers on the use of COVID-19 vaccines for patients with rheumatic and musculoskeletal diseases (RMDs).
Paul F. Dellaripa, Thomas Bush, Frederick W. Miller, Candace H. Feldman
doi : 10.1002/art.42279
Peter Stoustrup, Cory M. Resnick, Shelly Abramowicz, Thomas K. Pedersen, Ambra Michelotti, Annelise Küseler, Bernd Koos, Carlalberta Verna, Ellen B. Nordal, Eric J. Granquist, Josefine Mareile Halbig, Kasper D. Kristensen, Leonard B. Kaban, Linda Z. Arvidsson, Lynn Spiegel, Matthew L. Stoll, Melissa A. Lerman, Mia Glerup, Patrizia Defabianis, Paula Frid, Per Alstergren, Randy Q. Cron, Sarah Ringold, Sven Erik Nørholt, Timo Peltomaki, Tore A. Larheim, Troels Herlin, Zachary S. Peacock, Christian J. Kellenberger, Marinka Twilt, on behalf of the Temporomandibular Joint Juvenile Arthritis Working Group
doi : 10.1002/art.42338
Involvement of the temporomandibular joint (TMJ) is common in juvenile idiopathic arthritis (JIA). TMJ arthritis can lead to orofacial symptoms, orofacial dysfunction, and dentofacial deformity with negative impact on quality of life.
Paul Studenic, Daniel Aletaha, Maarten de Wit, Tanja A. Stamm, Farideh Alasti, Diane Lacaille, Josef S. Smolen, David T. Felson
doi : 10.1002/art.42347
In 2011, the American College of Rheumatology (ACR) and EULAR endorsed provisional criteria for remission in rheumatoid arthritis (RA), both Boolean- and index-based.
Kanon Jatuworapruk, Nicola Dalbeth
doi : 10.1002/art.42322
doi : 10.1002/art.42367
Christopher M. Dunn, Cassandra Sturdy, Cassandra Velasco, Leoni Schlupp, Emmaline Prinz, Vladislav Izda, Liubov Arbeeva, Yvonne M. Golightly, Amanda E. Nelson, Matlock A. Jeffries
doi : 10.1002/art.42316
The lack of accurate biomarkers to predict knee osteoarthritis (OA) progression is a key unmet need in OA clinical research. The objective of this study was to develop baseline peripheral blood epigenetic biomarker models to predict knee OA progression.
Magali Berland, Victoria Meslier, Samar Berreira Ibraim, Emmanuelle Le Chatelier, Nicolas Pons, Nicolas Maziers, Florence Thirion, Franck Gauthier, Florian Plaza Oñate, Jean-Pierre Furet, Ariane Leboime, Roula Said-Nahal, Florence Levenez, Nathalie Galleron, Benoît Quinquis, Philippe Langella, Stanislav Dusko Ehrlich, Maxime Breban
doi : 10.1002/art.42289
Gut microbiome dysbiosis has previously been reported in spondyloarthritis (SpA) patients and could be critically involved in the pathogenesis of this disorder.
Ananta Paine, Paul S. Brookes, Soumyaroop Bhattacharya, Dongmei Li, Maria De La Luz Garcia-Hernandez, Francisco Tausk, Christopher Ritchlin
doi : 10.1002/art.42288
The transition from psoriasis to psoriatic arthritis (PsA) occurs in 20–30% of patients; however, the mechanisms underlying the emergence of musculoskeletal disease are not well understood.
Fernanda Flórez-Barrós, Simon Freeley, El Li Tham, Michael G. Robson
doi : 10.1002/art.42298
Antineutrophil cytoplasmic antibody–associated vasculitis (AAV) is a systemic autoimmune disease in which glomerulonephritis is an important manifestation. Antibodies against myeloperoxidase (MPO) or proteinase 3 are thought to be important in pathogenesis.
Takashi Kudo, Daigo Nakazawa, Kanako Watanabe-Kusunoki, Masatoshi Kanda, Satoka Shiratori-Aso, Nobuya Abe, Saori Nishio, Jun-ichiro Koga, Sari Iwasaki, Takahiro Tsuji, Yuichiro Fukasawa, Miwako Yamasaki, Masahiko Watanabe, Sakiko Masuda, Utano Tomaru, Masaaki Murakami, Yasuaki Aratani, Akihiro Ishizu, Tatsuya Atsumi
doi : 10.1002/art.42314
Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) is pathologically characterized by focal fibrinoid necrosis, in which ANCA-mediated neutrophil extracellular trap (NET) formation and subsequent endothelial cell necrosis occur.
Maria Prendecki, Kavita Gulati, Noelle Pisacano, Damilola Pinheiro, Tejal Bhatt, Marie-Anne Mawhin, Frederic Toulza, Esteban S. Masuda, Andrew Cowburn, Katharine M. Lodge, Frederick W. K. Tam, Candice Roufosse, Charles D. Pusey, Stephen P. McAdoo
doi : 10.1002/art.42321
Syk is a cytoplasmic protein tyrosine kinase that plays a role in signaling via B cell and Fc receptors (FcR). FcR engagement and signaling via Syk is thought to be important in antineutrophil cytoplasm antibody (ANCA) IgG–mediated neutrophil activation.
Kaitlin A. Quinn, Mark A. Ahlman, Hugh D. Alessi, Michael P. LaValley, Tuhina Neogi, Jamie Marko, Elaine Novakovich, Peter C. Grayson
doi : 10.1002/art.42290
To assess whether vascular activity seen on 18F-fluorodeoxyglucose–positron emission tomography (FDG-PET) scan is associated with angiographic change in large vessel vasculitis (LVV).
Elisha D. O. Roberson, Mary Carns, Li Cao, Kathleen Aren, Isaac A. Goldberg, David J. Morales-Heil, Benjamin D. Korman, John P. Atkinson, John Varga
doi : 10.1002/art.42281
Systemic sclerosis (SSc) is characterized by immune activation, vasculopathy, and unresolving fibrosis in the skin, lungs, and other organs. We performed RNA-sequencing analysis on skin biopsy samples and peripheral blood mononuclear cells (PBMCs) from SSc patients and unaffected controls to better understand the pathogenesis of SSc.
Matthew A. Sherman, Hemalatha Srinivasalu, A. Yasmine Kirkorian, Michael A. Cardis
doi : 10.1002/art.42326
Kazu Hamada-Ode, Yoshinori Taniguchi, Marina Osaki, Rika Yoshimatsu, Noriko Nitta
doi : 10.1002/art.42317
Dongxing Xie, Hyon K. Choi, Nicola Dalbeth, Zachary S. Wallace, Jeffrey A. Sparks, Na Lu, Chao Zeng, Xiaoxiao Li, Jie Wei, Guanghua Lei, Yuqing Zhang
doi : 10.1002/art.42339
Gout patients often have multiple comorbidities, making them susceptible to SARS–CoV-2 infection and poor outcomes. This study was undertaken to examine the association between gout and the risk of SARS–CoV-2 infection and severe outcomes, especially in patients who have received a SARS–CoV-2 vaccine.
Joshua F. Baker, David R. Weber, Tuhina Neogi, Michael D. George, Jin Long, Lindsay N. Helget, Bryant R. England, Ted R. Mikuls
doi : 10.1002/art.42301
Controversy remains as to whether low serum urate or uric acid (UA) levels contribute to adverse outcomes. We evaluated the relation between low serum UA levels and sarcopenia and assessed whether sarcopenia confounds associations between these low levels and mortality.
John D. Biglands, Bara Erhayiem, Graham Fent, John P. Greenwood, Raluca B. Dumitru, Jacqueline Andrews, Paul Emery, Maya H. Buch, Sven Plein
doi : 10.1002/art.42341
Qi Huang, Wang-Dong Xu
doi : 10.1002/art.42332
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