Journal of the Neurological Sciences




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سفارش

Care resources in the United States for patients with parkinsonism

Aaron Daley*, Michael J. Aminoff

doi : 10.1016/j.jns.2022.120502

Volume 444, 15 January 2023, 120502

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Spinocerebellar ataxia type 31: A clinical and radiological literature review

Jacob Saucier a,*, Mohammad Al-Qadi a, Mouna Ben Amor a,b, Kinya Ishikawa c,d, Ludivine Chamard-Witkowski

doi : 10.1016/j.jns.2022.120527

Volume 444, 15 January 2023, 120527

Spinocerebellar ataxia type 31 (SCA31) is an autosomal dominant disease, classified amongst pure cerebellar ataxias (ADCA type 3). While SCA31 is the third most prevalent autosomal dominant ataxia in Japan, it is extremely rare in other countries. A literature review was conducted on PubMed, where we included all case reports and studies describing the clinical presentation of original SCA31 cases.

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Stroke mortality prediction using machine learning: systematic review

Lihi Schwartz a,*, Roi Anteby b, Eyal Klang c,d,e, Shelly Soffer

doi : 10.1016/j.jns.2022.120529

Volume 444, 15 January 2023, 120529

Accurate prognostication of stroke may help in appropriate therapy and rehabilitation planning. In the past few years, several machine learning (ML) algorithms were applied for prediction of stroke outcomes.

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Permanent non-progressive cinnarizine and flunarizine-induced parkinsonism: An under-recognized tardive syndrome in the elderly?

Stefano Calzetti *, Anna Negrotti

doi : 10.1016/j.jns.2022.120526

Volume 444, 15 January 2023, 120526

Secondary parkinsonism induced by exposure to dopamine (DA) receptor antagonists as first and second generation antipsychotics, DA storage depleters, calcium channel blockers, benzamides substituted and other classes of drugs is traditionally believed to be completely reversible in most of patients following withdrawal of the offending drug even though after a variable time delay.

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Long-term motor outcomes of deep brain stimulation of the globus pallidus interna in Parkinson's disease patients: Five-year follow-up

Yun Su Hwang a,b,c, Sungyang Jo a, Seung Hyun Lee a, Nayoung Kim d, Mi-Sun Kim a, Sang Ryong Jeon e, Sun Ju Chung

doi : 10.1016/j.jns.2022.120484

Volume 444, 15 January 2023, 120484

Deep brain stimulation (DBS) of globus pallidus interna (GPi) is an established treatment for advanced Parkinson's disease (PD). However, in contrast to subthalamic nucleus (STN)-DBS, long-term outcomes of GPi-DBS have rarely been studied.

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The diagnostic experience for people with MND and their caregivers in the U.K.

Mary R. O’Brien a, Christopher McDermott b, Samar Aoun c, David Oliver d, Jennifer A. Kirton

doi : 10.1016/j.jns.2022.120483

Volume 444, 15 January 2023, 120483

How an MND diagnosis is communicated has implications for how individuals adapt to their illness. The consultation process with the neurologist, diagnosis delivery, and adherence to UK guidelines, were explored from the perspectives of people diagnosed with MND and family caregivers.

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SARS-CoV-2 infection might be a predictor of mortality in intracerebral hemorrhage

Ashkan Mowla a,1, Banafsheh Shakibajahromi b,2,1, Shima Shahjouei c, Humain Baharvahdat d, Ali Amini Harandi e, Farzad Rahmani f, Stefania Mondello g, Nasrin Rahimian h, Achille Cernigliaro i, Elyar Sadeghi Hokmabadi j, Seyed Amir Ebrahimzadeh k, Mahtab Ramezani l, Kaveh Mehrvar m, Mehdi Farhoudi j, Soheil Naderi n, Shahab Mahmoudnejad Fenderi d, Masoud Pishjoo d, Orkhan Alizada o, Francisco Purroy p, Manuel Requena q, Georgios Tsivgoulis r, Ramin Zand

doi : 10.1016/j.jns.2022.120497

Volume 444, 15 January 2023, 120497

SARS-CoV-2 infection may be associated with uncommon complications such as intracerebral hemorrhage (ICH), with a high mortality rate. We compared a series of hospitalized ICH cases infected with SARS-CoV-2 with a non-SARS-CoV-2 infected control group and evaluated if the SARS-CoV-2 infection is a predictor of mortality in ICH patients.

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Serum C3 complement levels predict prognosis and monitor disease activity in Guillain-Barré syndrome

Young Gi Min a,b, Woohee Ju a, Jae-Woo Seo a, Ye-Eun Ha a, Jae-Jun Ban a, Young Nam Kwon a,g, Han-Yeong Jeong c, Je-Young Shin d, Sung-Min Kim a, Yoon-Ho Hong e, Sang-Jeong Kim f,h, Jung-Joon Sung

doi : 10.1016/j.jns.2022.120512

Volume 444, 15 January 2023, 120512

Biomarkers are needed to predict prognosis and disease activity in patients with Guillain-Barré syndrome (GBS). The complement system is a key player in the pathogenesis of GBS. This study aimed to assess the potential utility of serum complement proteins as novel biomarkers in GBS.

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Monitoring cognitive and psychological alterations in COVID-19 patients: A longitudinal neuropsychological study

Lorenzo Diana a,b, Rossana Regazzoni a, Matteo Sozzi a, Stefania Piconi c, Luca Borghesi c, Elisa Lazzaroni d, Paola Basilico a, Angelo Aliprandi a, Nadia Bolognini b,e, Daniela R. Bonardi f, Daniele Colombo f, Andrea Salmaggi

doi : 10.1016/j.jns.2022.120511

Volume 444, 15 January 2023, 120511

SARS-COV-2 infection has been associated to long-lasting neuropsychiatric sequelae, including cognitive deficits, that persist after one year. However, longitudinal monitoring has been scarcely performed. Here, in a sample of COVID-19 patients, we monitor cognitive, psychological and quality of life-related profiles up to 22 months from resolution of respiratory disease.

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Two pathways differentially linking tau depositions, oxidative stress, and neuronal loss to apathetic phenotypes in progressive supranuclear palsy

Kiwamu Matsuoka a,b, Yuhei Takado a,*, Kenji Tagai a, Manabu Kubota a,c, Yasunori Sano a, Keisuke Takahata a, Maiko Ono a, Chie Seki a, Hideki Matsumoto a,d, Hironobu Endo a, Hitoshi Shinotoh a,e, Yasuka Sahara f, Takayuki Obata f, Jamie Near g, Kazunori Kawamura h, Ming-Rong Zhang h, Tetsuya Suhara a, Hitoshi Shimada a,i,**, Makoto Higuchi

doi : 10.1016/j.jns.2022.120514

Volume 444, 15 January 2023, 120514

Patients with progressive supranuclear palsy (PSP) frequently exhibit apathy but the neuropathological processes leading to this phenotype remain elusive. We aimed to examine the involvement of tau protein depositions, oxidative stress (OS), and neuronal loss in the apathetic manifestation of PSP.

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Exploring the effect of glatiramer acetate on cerebral gray matter atrophy in multiple sclerosis

Mahmoud A. AbdelRazek a,*, Subhash Tummala b, Fariha Khalid b, Shahamat Tauhid b, Youmna Jalkh b, Samar Khalil b, Shelley Hurwitz c, Jonathan Zurawski b, Rohit Bakshi

doi : 10.1016/j.jns.2022.120501

Volume 444, 15 January 2023, 120501

Cerebral gray matter (GM) atrophy is a proposed measure of neuroprotection in multiple sclerosis (MS). Glatiramer acetate (GA) limits clinical relapses, MRI lesions, and whole brain atrophy in relapsing-remitting MS (RRMS). The effect of GA on GM atrophy remains unclear. We assessed GM atrophy in patients with RRMS starting GA therapy in comparison to a cohort of patients with clinically benign RRMS (BMS).

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Role of bedside video-oculography in selecting neuroimaging in patients with acute vertigo and ataxia posterior fossa mass lesions

Daniel R. Getz a, Anusha Mangalampalli a, Jeffrey Klopfenstein b, Andrew J. Tsung b, Jorge C. Kattah

doi : 10.1016/j.jns.2022.120513

Volume 444, 15 January 2023, 120513

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Unaltered T cell responses to common antigens in individuals with Parkinson's disease

Gregory P. Williams a,b, Kaylin Muskat a, April Frazier a,b, Yaqian Xu b,g, Jos �e Mateus a, Alba Grifoni a, Ricardo da Silva Antunes a, Daniela Weiskopf a, Amy W. Amara b,d, David G. Standaert b,d, Jennifer G. Goldman e, Irene Litvan f, Roy N. Alcalay h, David Sulzer b,c,i, Cecilia S. Lindestam Arlehamn a,b,*,1, Alessandro Sette

doi : 10.1016/j.jns.2022.120510

Volume 444, 15 January 2023, 120510

Parkinson's disease (PD) is associated with a heightened inflammatory state, including activated T cells. However, it is unclear whether these PD T cell responses are antigen specific or more indicative of generalized hyperresponsiveness.

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Pathological features of glial cells and motor neurons in the anterior horn of the spinal cord in sporadic ALS using ADAR2 conditional knockout mice

Makiko Naito 1, Takuto Hideyama *,1, Sayaka Teramoto, Tomoko Saito, Haruhisa Kato, Hiroo Terashi, Shin Kwak, Hitoshi Aizawa

doi : 10.1016/j.jns.2022.120520

Volume 444, 15 January 2023, 120520

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by the selective degeneration of motor neurons (MNs). In the MNs of patients with ALS, adenosine deaminase acting on RNA 2 (ADAR2)-mediated RNA editing of GluA2 mRNA at the Q/R site is profoundly deficient.

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An evaluation of surrogate decision maker health literacy in the neurology ward and neuroscience ICU

Elizabeth Carroll a,*, Julie Giles a, Ariane Lewis

doi : 10.1016/j.jns.2022.120525

Volume 444, 15 January 2023, 120525

There has been little investigation into surrogate comprehension of education provided by the neuroscience healthcare team. We sought to evaluate 1) surrogate understanding about a patient's clinical condition and 2) the relationship between how surrogates and the neuroscience team perceive surrogate comprehension of a patient's condition.

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The interaction between metaplastic neuromodulation and fatigue in multiple sclerosis

Claire Xian a, Chiara Barbi b, Mitchell R. Goldsworthy c, Massimo Venturelli b, Simranjit K. Sidhu

doi : 10.1016/j.jns.2022.120521

Volume 444, 15 January 2023, 120521

Neuromuscular fatigue contributes to decrements in quality of life in Multiple Sclerosis (MS), yet available treatments demonstrate limited efficacy. Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique which presents promise in managing fatigue, possibly related to its capacity to modulate corticospinal excitability.

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Clinical features, risk factors and survival in cardiac myxoma-related ischemic stroke: A multicenter case-control study

Man-Li Qiao a,1, Lin Ma b,1, Chao-Bin Wang c, Li-Bo Fang d, Ze-Xin Fan b, Tian-Tong Niu b, Ze-Yi Wang b, Jian-Feng Lu b, Bo-Yi Yuan b, Guang-Zhi Liu

doi : 10.1016/j.jns.2022.120517

Volume 444, 15 January 2023, 120517

Cardiac myxoma (CM) is an important etiology of stroke in young adults, but studies on CM-related ischemic stroke (CM-IS) are limited and conflicting. Hence, we investigated clinical characterizations, risk factors of CM-IS, and short-term survival after surgical resection.

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Reevaluation of risk factors for aneurysmal subarachnoid hemorrhage associated epilepsy

Marvin Darkwah Oppong a,d,*, Lasse Lohrer a,d, Karsten H. Wrede a,d, Mehdi Chihi a,d, Alejandro N. Santos a,d, Philipp Dammann a,d, Anna Michel a,d, Laur`el Rauschenbach a,d, Maryam Said a,d, Yan Li b, Benedikt Frank c, Ulrich Sure a,d, Ramazan Jabbarli

doi : 10.1016/j.jns.2022.120519

Volume 444, 15 January 2023, 120519

Symptomatic epilepsy is a common complication of aneurysmal subarachnoid hemorrhage (aSAH) associated with poor outcome. We sought to analyze the risk factors leading to post-SAH epilepsy.

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Old thalamic lacunes contralateral to a supratentorial intracerebral hemorrhage are associated with an unfavorable outcome

Motohiro Okumura, Takeo Sato *, Takahiro Maku, Tomomichi Kitagawa, Hiroki Takatsu, Teppei Komatsu, Kenichi Sakuta, Kenichiro Sakai, Tadashi Umehara, Hidetaka Mitsumura, Hidetomo Murakami, Yasuyuki Iguchi

doi : 10.1016/j.jns.2022.120523

Volume 444, 15 January 2023, 120523

To determine the impact of old lacunes and their sites on the prognosis of one-sided supratentorial intracerebral hemorrhage (ICH) by classifying lacunes sites in relation to anatomical structures using MRI.

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Diagnostic utility of susceptibility-weighted imaging in amyotrophic lateral sclerosis

Masaaki Yasui, Jinsoo Koh *, Yoshiaki Nakayama, Mayumi Sakata, Yasuhiro Hiwatani, Hiroshi Ishiguchi, Hidefumi Ito

doi : 10.1016/j.jns.2022.120524

Volume 444, 15 January 2023, 120524

Susceptibility-weighted imaging (SWI) was developed as a diagnostic tool for amyotrophic lateral sclerosis (ALS). However, its sensitivity and specificity are insufficient for accurate diagnosis. Herein, we investigated a new, simple evaluation method for SWI as a diagnostic marker for ALS. We retrospectively investigated 36 patients with ALS and 19 healthy controls.

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How vestibular dysfunction transforms into symptoms of depersonalization and derealization?

Zohar Elyoseph a,b,1,*, Dario Geisinger c,1, Roy Zaltzman d, Carlos R. Gordon c,d,e, Matti Mintz

doi : 10.1016/j.jns.2022.120530

Volume 444, 15 January 2023, 120530

Psychiatric Depersonalization/Derealization (DPDR) symptoms were demonstrated in patients with peripheral vestibular disorders. However, only semicircular canals (SCCs) dysfunction was evaluated, therefore, otoliths' contribution to DPDR is unknown.

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Intracranial artery stenosis is associated with cortical thinning in stroke-free individuals of two longitudinal cohorts

Dixon Yang a, Arjun V. Masurkar b,c,d, Farid Khasiyev e, Tatjana Rundek f,g, Clinton B. Wright h, Mitchell S.V. Elkind a,i, Ralph L. Sacco f,g, Jose Gutierrez

doi : 10.1016/j.jns.2022.120533

Volume 444, 15 January 2023, 120533

We examined the association between asymptomatic intracranial artery stenosis (aICAS) and cortical thickness using brain magnetic resonance morphometry in two cohorts.

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Covid-19 associated free hanging clots in acute symptomatic carotid stenosis

Y. Schwartzmann a, R.R. Leker a, A. Filioglo a, J. Molad c, J.E. Cohen b, A. Honig

doi : 10.1016/j.jns.2022.120515

Volume 444, 15 January 2023, 120515

Thrombotic complications including stroke were previously described following Covid-19. We aim to describe the clinical and radiological characteristics of Covid-19 related with acutely symptomatic carotid stenosis (aSCS).

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Effect of multiple sclerosis disease-modifying therapies on the real-world effectiveness of two doses of BBIBP-CorV (Sinopharm) vaccine

Masoud Etemadifar a, Amir Parsa Abhari b,c, Hosein Nouri b,c, Naghme Eighani b, Mehri Salari d, Nahad Sedaghat

doi : 10.1016/j.jns.2022.120518

Volume 444, 15 January 2023, 120518

Immunogenicity data shows blunted responses to COVID-19 vaccination among people with MS (pwMS) on certain disease-modifying therapies (DMTs). Still, it is uncertain how this data translates into the clinic.

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Chimeric antigen receptor (CAR) T therapy and cognitive functions

Brendan Bryan Jen-Wei Tana , Shaun Kai Kiat Chua a,c , Qian Ying Soha,c , Ling-Ling Chanb,d , Eng-King Tan

doi : 10.1016/j.jns.2022.120495

Volume 444, 15 January 2023, 120495

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World Health Organization (WHO)’s Intersectoral Global Action Plan (IGAP); implications for Asian and African countries

Mohammad Wasaya,b,*, Safa Younisa,b, Augustina Charway-Fellic, Hamidon Basrid

doi : 10.1016/j.jns.2022.120499

Volume 444, 15 January 2023, 120499

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Long-COVID phenotypes and small fiber neuropathy

Franco Gemignania,*, Maria F. Bellanovab, Elena Saccanic a Neurology, University of Parma, Italy

doi : 10.1016/j.jns.2022.120490

Volume 444, 15 January 2023, 120490

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Response to the letter of Gemignani et al.

Stefano Giuseppe Grisantia,*, Margherita Belluccia, Francesco Germanoa, Cristina Schenonea, Emanuela Barisioneb, Sara Garbarinoc, Michele Pianac, Matteo Pardinia, Luana Benedetti

doi : 10.1016/j.jns.2022.120491

Volume 444, 15 January 2023, 120491

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Immune checkpoint inhibitor-related myositis and myocarditis with multiple myositis-specific/−associated antibodies

Megumi Isaa, Yu Hongoa, Naohiro Sakamotoa, Keishi Yamazakia, Hiroshi Takazakia, Junichi Asakumab, Katsunori Ikewakia, Kazushi Suzuki

doi : 10.1016/j.jns.2022.120528

Volume 444, 15 January 2023, 120528

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