Aaron Daley*, Michael J. Aminoff
doi : 10.1016/j.jns.2022.120502
Volume 444, 15 January 2023, 120502
Jacob Saucier a,*, Mohammad Al-Qadi a, Mouna Ben Amor a,b, Kinya Ishikawa c,d, Ludivine Chamard-Witkowski
doi : 10.1016/j.jns.2022.120527
Volume 444, 15 January 2023, 120527
Spinocerebellar ataxia type 31 (SCA31) is an autosomal dominant disease, classified amongst pure cerebellar ataxias (ADCA type 3). While SCA31 is the third most prevalent autosomal dominant ataxia in Japan, it is extremely rare in other countries. A literature review was conducted on PubMed, where we included all case reports and studies describing the clinical presentation of original SCA31 cases.
Lihi Schwartz a,*, Roi Anteby b, Eyal Klang c,d,e, Shelly Soffer
doi : 10.1016/j.jns.2022.120529
Volume 444, 15 January 2023, 120529
Accurate prognostication of stroke may help in appropriate therapy and rehabilitation planning. In the past few years, several machine learning (ML) algorithms were applied for prediction of stroke outcomes.
Stefano Calzetti *, Anna Negrotti
doi : 10.1016/j.jns.2022.120526
Volume 444, 15 January 2023, 120526
Secondary parkinsonism induced by exposure to dopamine (DA) receptor antagonists as first and second generation antipsychotics, DA storage depleters, calcium channel blockers, benzamides substituted and other classes of drugs is traditionally believed to be completely reversible in most of patients following withdrawal of the offending drug even though after a variable time delay.
Yun Su Hwang a,b,c, Sungyang Jo a, Seung Hyun Lee a, Nayoung Kim d, Mi-Sun Kim a, Sang Ryong Jeon e, Sun Ju Chung
doi : 10.1016/j.jns.2022.120484
Volume 444, 15 January 2023, 120484
Deep brain stimulation (DBS) of globus pallidus interna (GPi) is an established treatment for advanced Parkinson's disease (PD). However, in contrast to subthalamic nucleus (STN)-DBS, long-term outcomes of GPi-DBS have rarely been studied.
Mary R. O’Brien a, Christopher McDermott b, Samar Aoun c, David Oliver d, Jennifer A. Kirton
doi : 10.1016/j.jns.2022.120483
Volume 444, 15 January 2023, 120483
How an MND diagnosis is communicated has implications for how individuals adapt to their illness. The consultation process with the neurologist, diagnosis delivery, and adherence to UK guidelines, were explored from the perspectives of people diagnosed with MND and family caregivers.
Ashkan Mowla a,1, Banafsheh Shakibajahromi b,2,1, Shima Shahjouei c, Humain Baharvahdat d, Ali Amini Harandi e, Farzad Rahmani f, Stefania Mondello g, Nasrin Rahimian h, Achille Cernigliaro i, Elyar Sadeghi Hokmabadi j, Seyed Amir Ebrahimzadeh k, Mahtab Ramezani l, Kaveh Mehrvar m, Mehdi Farhoudi j, Soheil Naderi n, Shahab Mahmoudnejad Fenderi d, Masoud Pishjoo d, Orkhan Alizada o, Francisco Purroy p, Manuel Requena q, Georgios Tsivgoulis r, Ramin Zand
doi : 10.1016/j.jns.2022.120497
Volume 444, 15 January 2023, 120497
SARS-CoV-2 infection may be associated with uncommon complications such as intracerebral hemorrhage (ICH), with a high mortality rate. We compared a series of hospitalized ICH cases infected with SARS-CoV-2 with a non-SARS-CoV-2 infected control group and evaluated if the SARS-CoV-2 infection is a predictor of mortality in ICH patients.
Young Gi Min a,b, Woohee Ju a, Jae-Woo Seo a, Ye-Eun Ha a, Jae-Jun Ban a, Young Nam Kwon a,g, Han-Yeong Jeong c, Je-Young Shin d, Sung-Min Kim a, Yoon-Ho Hong e, Sang-Jeong Kim f,h, Jung-Joon Sung
doi : 10.1016/j.jns.2022.120512
Volume 444, 15 January 2023, 120512
Biomarkers are needed to predict prognosis and disease activity in patients with Guillain-Barré syndrome (GBS). The complement system is a key player in the pathogenesis of GBS. This study aimed to assess the potential utility of serum complement proteins as novel biomarkers in GBS.
Lorenzo Diana a,b, Rossana Regazzoni a, Matteo Sozzi a, Stefania Piconi c, Luca Borghesi c, Elisa Lazzaroni d, Paola Basilico a, Angelo Aliprandi a, Nadia Bolognini b,e, Daniela R. Bonardi f, Daniele Colombo f, Andrea Salmaggi
doi : 10.1016/j.jns.2022.120511
Volume 444, 15 January 2023, 120511
SARS-COV-2 infection has been associated to long-lasting neuropsychiatric sequelae, including cognitive deficits, that persist after one year. However, longitudinal monitoring has been scarcely performed. Here, in a sample of COVID-19 patients, we monitor cognitive, psychological and quality of life-related profiles up to 22Â months from resolution of respiratory disease.
Kiwamu Matsuoka a,b, Yuhei Takado a,*, Kenji Tagai a, Manabu Kubota a,c, Yasunori Sano a, Keisuke Takahata a, Maiko Ono a, Chie Seki a, Hideki Matsumoto a,d, Hironobu Endo a, Hitoshi Shinotoh a,e, Yasuka Sahara f, Takayuki Obata f, Jamie Near g, Kazunori Kawamura h, Ming-Rong Zhang h, Tetsuya Suhara a, Hitoshi Shimada a,i,**, Makoto Higuchi
doi : 10.1016/j.jns.2022.120514
Volume 444, 15 January 2023, 120514
Patients with progressive supranuclear palsy (PSP) frequently exhibit apathy but the neuropathological processes leading to this phenotype remain elusive. We aimed to examine the involvement of tau protein depositions, oxidative stress (OS), and neuronal loss in the apathetic manifestation of PSP.
Mahmoud A. AbdelRazek a,*, Subhash Tummala b, Fariha Khalid b, Shahamat Tauhid b, Youmna Jalkh b, Samar Khalil b, Shelley Hurwitz c, Jonathan Zurawski b, Rohit Bakshi
doi : 10.1016/j.jns.2022.120501
Volume 444, 15 January 2023, 120501
Cerebral gray matter (GM) atrophy is a proposed measure of neuroprotection in multiple sclerosis (MS). Glatiramer acetate (GA) limits clinical relapses, MRI lesions, and whole brain atrophy in relapsing-remitting MS (RRMS). The effect of GA on GM atrophy remains unclear. We assessed GM atrophy in patients with RRMS starting GA therapy in comparison to a cohort of patients with clinically benign RRMS (BMS).
Daniel R. Getz a, Anusha Mangalampalli a, Jeffrey Klopfenstein b, Andrew J. Tsung b, Jorge C. Kattah
doi : 10.1016/j.jns.2022.120513
Volume 444, 15 January 2023, 120513
Gregory P. Williams a,b, Kaylin Muskat a, April Frazier a,b, Yaqian Xu b,g, Jos �e Mateus a, Alba Grifoni a, Ricardo da Silva Antunes a, Daniela Weiskopf a, Amy W. Amara b,d, David G. Standaert b,d, Jennifer G. Goldman e, Irene Litvan f, Roy N. Alcalay h, David Sulzer b,c,i, Cecilia S. Lindestam Arlehamn a,b,*,1, Alessandro Sette
doi : 10.1016/j.jns.2022.120510
Volume 444, 15 January 2023, 120510
Parkinson's disease (PD) is associated with a heightened inflammatory state, including activated T cells. However, it is unclear whether these PD T cell responses are antigen specific or more indicative of generalized hyperresponsiveness.
Makiko Naito 1, Takuto Hideyama *,1, Sayaka Teramoto, Tomoko Saito, Haruhisa Kato, Hiroo Terashi, Shin Kwak, Hitoshi Aizawa
doi : 10.1016/j.jns.2022.120520
Volume 444, 15 January 2023, 120520
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by the selective degeneration of motor neurons (MNs). In the MNs of patients with ALS, adenosine deaminase acting on RNA 2 (ADAR2)-mediated RNA editing of GluA2 mRNA at the Q/R site is profoundly deficient.
Elizabeth Carroll a,*, Julie Giles a, Ariane Lewis
doi : 10.1016/j.jns.2022.120525
Volume 444, 15 January 2023, 120525
There has been little investigation into surrogate comprehension of education provided by the neuroscience healthcare team. We sought to evaluate 1) surrogate understanding about a patient's clinical condition and 2) the relationship between how surrogates and the neuroscience team perceive surrogate comprehension of a patient's condition.
Claire Xian a, Chiara Barbi b, Mitchell R. Goldsworthy c, Massimo Venturelli b, Simranjit K. Sidhu
doi : 10.1016/j.jns.2022.120521
Volume 444, 15 January 2023, 120521
Neuromuscular fatigue contributes to decrements in quality of life in Multiple Sclerosis (MS), yet available treatments demonstrate limited efficacy. Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique which presents promise in managing fatigue, possibly related to its capacity to modulate corticospinal excitability.
Man-Li Qiao a,1, Lin Ma b,1, Chao-Bin Wang c, Li-Bo Fang d, Ze-Xin Fan b, Tian-Tong Niu b, Ze-Yi Wang b, Jian-Feng Lu b, Bo-Yi Yuan b, Guang-Zhi Liu
doi : 10.1016/j.jns.2022.120517
Volume 444, 15 January 2023, 120517
Cardiac myxoma (CM) is an important etiology of stroke in young adults, but studies on CM-related ischemic stroke (CM-IS) are limited and conflicting. Hence, we investigated clinical characterizations, risk factors of CM-IS, and short-term survival after surgical resection.
Marvin Darkwah Oppong a,d,*, Lasse Lohrer a,d, Karsten H. Wrede a,d, Mehdi Chihi a,d, Alejandro N. Santos a,d, Philipp Dammann a,d, Anna Michel a,d, Laur`el Rauschenbach a,d, Maryam Said a,d, Yan Li b, Benedikt Frank c, Ulrich Sure a,d, Ramazan Jabbarli
doi : 10.1016/j.jns.2022.120519
Volume 444, 15 January 2023, 120519
Symptomatic epilepsy is a common complication of aneurysmal subarachnoid hemorrhage (aSAH) associated with poor outcome. We sought to analyze the risk factors leading to post-SAH epilepsy.
Motohiro Okumura, Takeo Sato *, Takahiro Maku, Tomomichi Kitagawa, Hiroki Takatsu, Teppei Komatsu, Kenichi Sakuta, Kenichiro Sakai, Tadashi Umehara, Hidetaka Mitsumura, Hidetomo Murakami, Yasuyuki Iguchi
doi : 10.1016/j.jns.2022.120523
Volume 444, 15 January 2023, 120523
To determine the impact of old lacunes and their sites on the prognosis of one-sided supratentorial intracerebral hemorrhage (ICH) by classifying lacunes sites in relation to anatomical structures using MRI.
Masaaki Yasui, Jinsoo Koh *, Yoshiaki Nakayama, Mayumi Sakata, Yasuhiro Hiwatani, Hiroshi Ishiguchi, Hidefumi Ito
doi : 10.1016/j.jns.2022.120524
Volume 444, 15 January 2023, 120524
Susceptibility-weighted imaging (SWI) was developed as a diagnostic tool for amyotrophic lateral sclerosis (ALS). However, its sensitivity and specificity are insufficient for accurate diagnosis. Herein, we investigated a new, simple evaluation method for SWI as a diagnostic marker for ALS. We retrospectively investigated 36 patients with ALS and 19 healthy controls.
Zohar Elyoseph a,b,1,*, Dario Geisinger c,1, Roy Zaltzman d, Carlos R. Gordon c,d,e, Matti Mintz
doi : 10.1016/j.jns.2022.120530
Volume 444, 15 January 2023, 120530
Psychiatric Depersonalization/Derealization (DPDR) symptoms were demonstrated in patients with peripheral vestibular disorders. However, only semicircular canals (SCCs) dysfunction was evaluated, therefore, otoliths' contribution to DPDR is unknown.
Dixon Yang a, Arjun V. Masurkar b,c,d, Farid Khasiyev e, Tatjana Rundek f,g, Clinton B. Wright h, Mitchell S.V. Elkind a,i, Ralph L. Sacco f,g, Jose Gutierrez
doi : 10.1016/j.jns.2022.120533
Volume 444, 15 January 2023, 120533
We examined the association between asymptomatic intracranial artery stenosis (aICAS) and cortical thickness using brain magnetic resonance morphometry in two cohorts.
Y. Schwartzmann a, R.R. Leker a, A. Filioglo a, J. Molad c, J.E. Cohen b, A. Honig
doi : 10.1016/j.jns.2022.120515
Volume 444, 15 January 2023, 120515
Thrombotic complications including stroke were previously described following Covid-19. We aim to describe the clinical and radiological characteristics of Covid-19 related with acutely symptomatic carotid stenosis (aSCS).
Masoud Etemadifar a, Amir Parsa Abhari b,c, Hosein Nouri b,c, Naghme Eighani b, Mehri Salari d, Nahad Sedaghat
doi : 10.1016/j.jns.2022.120518
Volume 444, 15 January 2023, 120518
Immunogenicity data shows blunted responses to COVID-19 vaccination among people with MS (pwMS) on certain disease-modifying therapies (DMTs). Still, it is uncertain how this data translates into the clinic.
Brendan Bryan Jen-Wei Tana , Shaun Kai Kiat Chua a,c , Qian Ying Soha,c , Ling-Ling Chanb,d , Eng-King Tan
doi : 10.1016/j.jns.2022.120495
Volume 444, 15 January 2023, 120495
Mohammad Wasaya,b,*, Safa Younisa,b, Augustina Charway-Fellic, Hamidon Basrid
doi : 10.1016/j.jns.2022.120499
Volume 444, 15 January 2023, 120499
Franco Gemignania,*, Maria F. Bellanovab, Elena Saccanic a Neurology, University of Parma, Italy
doi : 10.1016/j.jns.2022.120490
Volume 444, 15 January 2023, 120490
Stefano Giuseppe Grisantia,*, Margherita Belluccia, Francesco Germanoa, Cristina Schenonea, Emanuela Barisioneb, Sara Garbarinoc, Michele Pianac, Matteo Pardinia, Luana Benedetti
doi : 10.1016/j.jns.2022.120491
Volume 444, 15 January 2023, 120491
Megumi Isaa, Yu Hongoa, Naohiro Sakamotoa, Keishi Yamazakia, Hiroshi Takazakia, Junichi Asakumab, Katsunori Ikewakia, Kazushi Suzuki
doi : 10.1016/j.jns.2022.120528
Volume 444, 15 January 2023, 120528
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