دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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The Law of Licensure and Quality Regulation
Nathan Cortez, J.D.
doi : 10.1056/NEJMp2201802
Vol. 387 No. 12
Pushing Back with Pills — Enhancing Access to Reproductive Health Drugs after Dobbs
Lewis A. Grossman, J.D., Ph.D.
doi : 10.1056/NEJMp2209377
The Seeds of Ignorance — Consequences of a Booming Betel-Nut Economy
William J. Moss, M.D.
doi : 10.1056/NEJMp2203571
Glycemia Reduction in Type 2 Diabetes — Glycemic Outcomes
doi : 10.1056/NEJMoa2200433
The comparative effectiveness of glucose-lowering medications for use with metformin to maintain target glycated hemoglobin levels in persons with type 2 diabetes is uncertain.
Glycemia Reduction in Type 2 Diabetes — Microvascular and Cardiovascular Outcomes
doi : 10.1056/NEJMoa2200436
Data are lacking on the comparative effectiveness of commonly used glucose-lowering medications, when added to metformin, with respect to microvascular and cardiovascular disease outcomes in persons with type 2 diabetes.
Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction
Scott D. Solomon, M.D., John J.V. McMurray, M.D., Brian Claggett, Ph.D., Rudolf A. de Boer, M.D., David DeMets, Ph.D., Adrian F. Hernandez, M.D., Silvio E. Inzucchi, M.D., Mikhail N. Kosiborod, M.D., Carolyn S.P. Lam, M.D., Felipe Martinez, M.D., Sanjiv J. Shah, M.D., Akshay S. Desai, M.D.,
doi : 10.1056/NEJMoa2206286
Sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of hospitalization for heart failure and cardiovascular death among patients with chronic heart failure and a left ventricular ejection fraction of 40% or less. Whether SGLT2 inhibitors are effective in patients with a higher left ventricular ejection fraction remains less certain.
Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS
Timothy M. Miller, M.D., Ph.D., Merit E. Cudkowicz, M.D., Angela Genge, M.D., Pamela J. Shaw, M.B., B.S., M.D., Gen Sobue, M.D., Ph.D., Robert C. Bucelli, M.D., Ph.D., Adriano Chiò, M.D., Philip Van Damme, M.D., Ph.D., Albert C. Ludolph, M.D., Jonathan D. Glass, M.D., Jinsy A. Andrews, M.D., Suma Babu, M.B., B.S., M.P.H.,
doi : 10.1056/NEJMoa2204705
The intrathecally administered antisense oligonucleotide tofersen reduces synthesis of the superoxide dismutase 1 (SOD1) protein and is being studied in patients with amyotrophic lateral sclerosis (ALS) associated with mutations in SOD1 (SOD1 ALS).
Burkitt’s Lymphoma
Mark Roschewski, M.D., Louis M. Staudt, M.D., Ph.D., and Wyndham H. Wilson, M.D., Ph.D.
doi : 10.1056/NEJMra2025746
Jackstone Calculus in the Bladder
Jiyu Zhao, M.D., and Xianen Gu, M.Med.
doi : 10.1056/NEJMicm2119095
Wellens’ Syndrome
Sakiko Honda, M.D., Ph.D., and Tatsuya Kawasaki, M.D., Ph.D.
doi : 10.1056/NEJMicm2201699
Case 29-2022: A 33-Year-Old Man with Chronic Diarrhea and Autoimmune Enteropathy
Francis P. Colizzo, M.D., Stuti G. Shroff, M.B., B.S., Ph.D., Frances A. High, M.D., Ph.D., Yi-Bin Chen, M.D., and Sara Barmettler, M.D.
doi : 10.1056/NEJMcpc2201236
After Metformin — Next Steps for Type 2 Diabetes with Low Cardiovascular Risk
Lars Rydén, M.D., and Eberhard Standl, M.D., Ph.D.
doi : 10.1056/NEJMe2210531
DELIVERing Progress in Heart Failure with Preserved Ejection Fraction
Kenneth B. Margulies, M.D.
doi : 10.1056/NEJMe2210177
Audio Interview: Can Vaccines Prevent Transmission of Covid-19?
Eric J. Rubin, M.D., Ph.D., Lindsey R. Baden, M.D., and Stephen Morrissey, Ph.D.
doi : 10.1056/NEJMe2212576
Effects of Vaccination and Previous Infection on Omicron Infections in Children
doi : 10.1056/NEJMc2209371
