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Informing the Debate about Telemedicine Reimbursement — What Do We Need to Know?
Ateev Mehrotra, M.D., and Lori Uscher-Pines, Ph.D.
doi : 10.1056/NEJMp2210790
Vol. 387 No. 20
Health Care Access on the Line — Audio-Only Visits and Digitally Inclusive Care
Helen K. Hughes, M.D., M.P.H., Brian W. Hasselfeld, M.D., and Jeremy A. Greene, M.D., Ph.D.
doi : 10.1056/NEJMp2118292
Monkeypox — A Sobering Sentinel for Pandemic Preparedness and Sexual Health System Capacity
Matthew R. Golden, M.D., M.P.H., and Judith N. Wasserheit, M.D., M.P.H.
doi : 10.1056/NEJMp2212262
COP27 Climate Change Conference — Urgent Action Needed for Africa and the World
Lukoye Atwoli, Gregory E. Erhabor, Aiah A. Gbakima, Abraham Haileamlak, Jean-Marie Kayembe Ntumba, James Kigera, Laurie Laybourn-Langton, Bob Mash, Joy Muhia, Fhumulani Mavis Mulaudzi, David Ofori-Adjei, Friday Okonofua,
doi : 10.1056/NEJMp2213503
A Good Catch
Oscar F. Lovelace, Jr., M.D., Debra Malina, Ph.D., and Mark A. Pacult, M.D.
doi : 10.1056/NEJMp2213554
Safety and Efficacy of a Monoclonal Antibody against Malaria in Mali
Kassoum Kayentao, M.D., Ph.D., M.P.H., Aissata Ongoiba, M.D., M.P.H., Anne C. Preston, R.N., Sara A. Healy, M.D., M.P.H., Safiatou Doumbo, M.D., Ph.D., Didier Doumtabe, Pharm.D., Abdrahamane Traore, M.D., Hamadi Traore, M.D., Adama Djiguiba, M.D., Shanping Li, M.S., Mary E. Peterson, B.S., Shinyi Telscher, Pharm.D.,
doi : 10.1056/NEJMoa2206966
CIS43LS is a monoclonal antibody that was shown to protect against controlled Plasmodium falciparum infection in a phase 1 clinical trial. Whether a monoclonal antibody can prevent P. falciparum infection in a region in which the infection is endemic is unknown.
Spontaneous-Breathing Trials with Pressure- Support Ventilation or a T-Piece
Arnaud W. Thille, M.D., Ph.D., Arnaud Gacouin, M.D., Rémi Coudroy, M.D., Ph.D., Stephan Ehrmann, M.D., Ph.D., Jean-Pierre Quenot, M.D., Ph.D., Mai-Anh Nay, M.D., Christophe Guitton, M.D., Damien Contou, M.D., Guylaine Labro, M.D., Jean Reignier, M.D., Ph.D., Gael Pradel, M.D., Gaëtan Beduneau, M.D.,
doi : 10.1056/NEJMoa2209041
Spontaneous-breathing trials can be performed with the use of either pressure-support ventilation (PSV) or a T-piece. Whether PSV trials may result in a shorter time to tracheal extubation than T-piece trials, without resulting in a higher risk of reintubation, among patients who have a high risk of extubation failure is unknown.
Small Interfering RNA to Reduce Lipoprotein(a) in Cardiovascular Disease
Michelle L. O’Donoghue, M.D., M.P.H., Robert S. Rosenson, M.D., Baris Gencer, M.D., M.P.H., J. Antonio G. López, M.D., Norman E. Lepor, M.D., Seth J. Baum, M.D., Elmer Stout, M.D., Daniel Gaudet, M.D., Ph.D., Beat Knusel, Ph.D., Julia F. Kuder, M.A., Xinhui Ran, M.S., Sabina A. Murphy, M.P.H.,
doi : 10.1056/NEJMoa2211023
Lipoprotein(a) is a presumed risk factor for atherosclerotic cardiovascular disease. Olpasiran is a small interfering RNA that reduces lipoprotein(a) synthesis in the liver.
Covid-19 Vaccine Protection among Children and Adolescents in Qatar
Hiam Chemaitelly, Ph.D., Sawsan AlMukdad, M.Sc., Houssein H. Ayoub, Ph.D., Heba N. Altarawneh, M.D., Peter Coyle, M.D., Patrick Tang, M.D., Ph.D., Hadi M. Yassine, Ph.D., Hebah A. Al-Khatib, Ph.D., Maria K. Smatti, M.Sc., Mohammad R. Hasan, Ph.D., Zaina Al-Kanaani, Ph.D., Einas Al-Kuwari, M.D.,
doi : 10.1056/NEJMoa2210058
The BNT162b2 vaccine against coronavirus disease 2019 (Covid-19) has been authorized for use in children 5 to 11 years of age and adolescents 12 to 17 years of age but in different antigen doses.
Iron Deposition from a Retained Intraocular Foreign Body
Kawtar Bouirig, M.D., and Ouafae Cherkaoui, M.D., Ph.D.
doi : 10.1056/NEJMicm2205233
Case 35-2022: A 60-Year-Old Man with Progressive Dyspnea, Neck Swelling, and a Lung Mass
Jennifer S. Temel, M.D., David M. Dudzinski, M.D., Subba R. Digumarthy, M.D., Colleen M. Keyes, M.D., Florence K. Keane, M.D., and Daniel Shepherd, M.D., Ph.D.
doi : 10.1056/NEJMcpc2211354
Monoclonal Antibodies against Malaria
Umberto D’Alessandro, M.D., Ph.D.
doi : 10.1056/NEJMe2213148
Improved Protocols for Ventilator Liberation
C. Corey Hardin, M.D., Ph.D.
doi : 10.1056/NEJMe2212594
Audio Interview: The FDA and Covid-19 Vaccines
Eric J. Rubin, M.D., Ph.D., Lindsey R. Baden, M.D., Peter Marks, M.D., Ph.D., and Stephen Morrissey, Ph.D.
doi : 10.1056/NEJMe2214911
