Marina Huijboom, MD a,b , Moniek Maarse, MD a,b,1 , Errol Aarnink, MD a,b,1 , Vincent van Dijk, MD, PhD a , Martin Swaans, MD, PhD a , Jeroen van der Heijden, MD, PhD c , Sander IJsselmuiden, MD, PhD d , Richard Folkeringa, MD, PhD e , Yuri Blaauw, MD, PhD f , Arif Elvan, MD, PhD g , Jeroen Stevenhagen, MD, PhD h , George Vlachojannis, MD, PhD i , Pepijn van der Voort, MD, PhD j , Sjoerd Westra, MD k , Marisevi Chaldoupi, MD, PhD l , Muchtiar Khan, MD m , Joris de Groot, MD, PhD b , Frank van der Kley, MD n , Nicolas van Mieghem, MD, PhD o , Ewoud van Dijk, MD, PhD p , Marcel Dijkgraaf, MD, PhD q , Jan Tijssen, MD, PhD r , and Lucas Boersma, MD, PhD a,b Nieuwegein, The Netherlands; Nieuwegein, The Netherlands
doi : 10.1016/j.ahj.2022.05.001
Volume 250, August 2022, Pages 45-56
Paul M. Hendriks, MD a,b , Liza D. van de Groep, MD c , Kevin M. Veen, MD, PhD d , Mitch C.J. van Thor, MD, PhD c , Sabrina Meertens, MSc e , Eric Boersma, MSc, PhD, FESC a,f , Karin A. Boomars, MD, PhD b , Marco C. Post, MD, PhD c,g , and Annemien E. van den Bosch, MD, PhD a The Netherlands
doi : 10.1016/j.ahj.2022.05.006
Volume 250, August 2022, Pages 34-44
Multiple biomarkers have been investigated in the risk stratification of patients with pulmonary arterial hypertension (PAH). This systematic review and meta-analysis is the first to investigate the prognostic value of (NT-pro)BNP in patients with PAH.
Aakash Garg, MD a , Amit Rout, MD b , Serdar Farhan, MD c , Sergio Waxman, MD d , Gennaro Giustino, MD b , Raj Tayal, MD e , Jinette Dawn Abbott, MD a , Kurt Huber, MD f , Dominick J. Angiolillo, MD, PhD g , and Sunil V. Rao, MD h Rhode Island, USA; Kentucky, USA; New York, USA; New Jersey, USA; Vienna, Austria; Florida, USA; NC, USA;
doi : 10.1016/j.ahj.2022.04.004
Volume 250, August 2022, Pages 1-10
Optimal dual antiplatelet therapy (DAPT) duration in patients at high bleeding risk (HBR) is not fully defined. We aimed to compare the safety and effectiveness of short-term DAPT (S-DAPT) with longer duration DAPT (L-DAPT) after percutaneous coronary intervention (PCI) with drug eluting stents (DES) in patients at HBR.
Anna E. Denoble, MD, MSCR a , Sarah A. Goldstein, MD b , Lauren E. Wein, BA c , Chad A. Grotegut, MD, MBA d , and Jerome J. Federspiel, MD, PhD c,e New Haven, CT
doi : 10.1016/j.ahj.2022.04.009
Volume 250, August 2022, Pages 11-22
To compare rates of severe maternal morbidity (SMM) for pregnant patients with a cardiac diagnosis classified by the modified World Health Organization (mWHO) classification to those without a cardiac diagnosis.
Jesper Jensen, MD, PhD a,b , Massar Omar, MD, PhD c,d,e , Mulham Ali, MD c,e , Peter H. Frederiksen, MD c,e , Caroline Kistorp, MD, PhD f,b , Christian Tuxen, MD, PhD g , Camilla F. Andersen, MD a , Julie H. Larsen, MD c , Mads Kristian Ersbøll, MD, PhD h , Lars Køber, MD, DmSc h,b , Finn Gustafsson, MD, DmSc h,b , Jens Faber, MD, DmSc i,b , Julie Lyng Forman, MSc, PhD j , Jacob Eifer Møller, MD, DmSc c,e,h,e , and Morten Schou, MD, PhD a,b Herlev, Denmark; Copenhagen, Denmark; Odense, Denmark
doi : 10.1016/j.ahj.2022.04.008
Volume 250, August 2022, Pages 57-65
Osamu Okazaki, MD, PhD a , Yorihiko Higashino, MD b , Koichi Yokoya, MD, PhD c , Yoshimori An, MD, PhD d , Kimihiko Tanizawa, PhD e , Yuki Imamura, MS e , Takuya Hayashi, MS f , Masaharu Akao, MD, PhD d , Ken Okumura, MD, PhD g , and Takeshi Yamashita, MD, PhD h Tokyo, Japan; Hyogo, Japan; Aichi, Japan; Kyoto, Japan; Kumamoto, Japan
doi : 10.1016/j.ahj.2022.05.009
Volume 250, August 2022, Pages 66-75
Lauren Gilstrap, MD a,b,c,# , Ronnie J. Zipkin, PhD c,d,# , Jonathan Aaron Barnes, MD a , Ashleigh King, MPH b , Alistair James O’Malley, PhD b,d , Thomas A. Gaziano, MD, MSc e,f , and Anna N.A. Tosteson, ScD b Lebanon, NH
doi : 10.1016/j.ahj.2022.04.007
Volume 250, August 2022, Pages 23-28
In clinical trials, sacubitril/valsartan has demonstrated significant survival benefits compared to angiotensin converting enzyme inhibitors or angiotensin receptor blockers (ACEi/ARB). Whether older patients with heart failure with reduced ejection fraction (HFrEF) benefit as much, due to higher rates of comorbidities, frailty and drug discontinuation, is unknown.
Iain S. Forrest, BS a,b,c,d , Lili Chan, MD a,c,e , Kumardeep Chaudhary, PhD a,c,d,f , Aparna Saha, MD a,c , Huei Hsun Wen, MD a,c , Cristina Liriano Cepin, MPH a,c , Carla Marquez-Luna, PhD a,d , Ghislain Rocheleau, PhD a,d , Judy Cho, MD a,c,d,e , Jagat Narula, MD g , Girish N. Nadkarni, MD a,c,e,h,#,∗, and Ron Do, PhD a,c,d,#,∗∗ New York, NY
doi : 10.1016/j.ahj.2022.04.006
Volume 250, August 2022, Pages 29-33
Genetic risk for coronary artery disease (CAD) is commonly measured with polygenic risk scores (PRS); yet, the relationship of atherosclerotic burden with PRS in healthy individuals not at high clinical risk for CAD (ie, without a high pooled cohort equations [PCE] score) is unknown.
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