Aging




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سفارش

Rapamycin treatment early in life reprograms aging: hyperfunction theory and clinical practice

Mikhail V. Blagosklonny

doi : 10.18632/aging.204354

Volume 14, Issue 20

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Lamin A to Z in normal aging

Stanley R. Primmer, Chen-Yu Liao, Oona M.P. Kummert, Brian K. Kennedy

doi : 10.18632/aging.204342

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Downregulation of senescence-associated secretory phenotype by knockdown of secreted frizzled-related protein 4 contributes to the prevention of skin aging

Kento Takaya, Toru Asou, Kazuo Kishi

doi : 10.18632/aging.204273

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Crosstalk between age accumulated DNA-damage and the SIRT1-AKT-GSK3ß axis in urine derived renal progenitor cells

Lars Erichsen, James Adjaye

doi : 10.18632/aging.204300

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Age-associated changes in microglia activation and Sirtuin-1- chromatin binding patterns

Liana V. Basova, Nikki Bortell, Bruno Conti, Howard S. Fox, Richard Milner, Maria Cecilia Garibaldi Marcondes

doi : 10.18632/aging.204329

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AR12 increases BAG3 expression which is essential for Tau and APP degradation via LC3-associated phagocytosis and macroautophagy

Paul Dent, Laurence Booth, Jane L. Roberts, Andrew Poklepovic, Jennifer Martinez, Derek Cridebring, Eric M. Reiman

doi : 10.18632/aging.204337

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Network analysis for the identification of hub genes and related molecules as potential biomarkers associated with the differentiation of bone marrow-derived stem cells into hepatocytes

Ying-Hao Han, Xin-Mei He, Seung-Jae Lee, Ying-Ying Mao, Xuan-Chen Liu, Hu-Nan Sun, Mei-Hua Jin, Taeho Kwon

doi : 10.18632/aging.204344

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Association between Epstein-Barr virus serological reactivation and psychological distress: a cross-sectional study of Japanese community-dwelling older adults

Hirotomo Yamanashi, Shogo Akabame, Jun Miyata, Yukiko Honda, Fumiaki Nonaka, Yuji Shimizu, Seiko Nakamichi, Shin-Ya Kawashiri, Mami Tamai, Kazuhiko Arima, Atsushi Kawakami, Kiyoshi Aoyagi, Takahiro Maeda

doi : 10.18632/aging.204345

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Combining stem cell rejuvenation and senescence targeting to synergistically extend lifespan

Prameet Kaur, Agimaa Otgonbaatar, Anupriya Ramamoorthy, Ellora Hui Zhen Chua, Nathan Harmston, Jan Gruber, Nicholas S. Tolwinski

doi : 10.18632/aging.204347

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α-Synuclein upregulates bim-mediated apoptosis by negatively regulating endogenous GCN5

Shofiul Azam, In-Su Kim, Dong-Kug Choi

doi : 10.18632/aging.204353

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Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese rats

He Tai, Xiao-Zheng Cui, Jia He, Zhi-Ming Lan, Shun-Min Li, Ling-Bing Li, Si-Cheng Yao, Xiao-Lin Jiang, Xian-Sheng Meng, Jin-Song Kuang

doi : 10.18632/aging.204304

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Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF

Xiao-Lin Jiang, He Tai, Jin-Song Kuang, Jing-Yi Zhang, Shi-Chao Cui, Yu-Xuan Lu, Shu-Bo Qi, Shi-Yu Zhang, Shun-Min Li, Jian-Ping Chen, Xian-Sheng Meng

doi : 10.18632/aging.204320

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Parthenolide targets NF-κB (P50) to inhibit HIF-1α-mediated metabolic reprogramming of HCC

Xiaorong Liu, Zhaofeng Gao, Xiaoguang Wang, Yiyu Shen

doi : 10.18632/aging.204339

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Identify miRNA-mRNA regulation pairs to explore potential pathogenesis of lung adenocarcinoma

Xingchen Fan, Xuan Zou, Cheng Liu, Shuang Peng, Shiyu Zhang, Xin Zhou, Jun Zhu, Wei Zhu

doi : 10.18632/aging.204341

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Identification of circRNA-miRNA-mRNA networks to explore the molecular mechanism and immune regulation of postoperative neurocognitive disorder

Ning Bao, Jiping Liu, Zhe Peng, Rong Zhang, Rufei Ni, Runzuan Li, Jian Wu, Zhenhua Liu, Botao Pan

doi : 10.18632/aging.204348

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Computational study on new natural compound inhibitors of Traf2 and Nck-interacting kinase (TNIK)

Lushun Ma, Rui Li, Zhiwei Yao, Bo Wang, Yong Liu, Chunxiang Liu, Heng Wang, Shuxian Chen, Daqing Sun

doi : 10.18632/aging.204349

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ZNF320 is a hypomethylated prognostic biomarker involved in immune infiltration of hepatocellular carcinoma and associated with cell cycle

Jing Zhen, Yun Ke, Jingying Pan, Minqin Zhou, Hong Zeng, Gelin Song, Zichuan Yu, Bidong Fu, Yue Liu, Da Huang, Honghu Wu

doi : 10.18632/aging.204350

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Gabrb2 knock-out mice exhibit double-directed PMDD-like symptoms: GABAAR subunits, neurotransmitter metabolism disruption, and allopregnanolone binding

Mingzhou Gao, Hao Zhang, Ya Sun, Zhan Gao, Chunyan Sun, Fengqin Wei, Dongmei Gao

doi : 10.18632/aging.204351

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Sex differences in major cardiovascular outcomes and fractures in patients with subclinical thyroid dysfunction: a systematic review and meta-analysis

Hongjuan Fang, Runsheng Zhao, Shuang Cui, Weiqing Wan

doi : 10.18632/aging.204352

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The regulatory mechanism of HSP70 in endoplasmic reticulum stress in pepsin-treated laryngeal epithelium cells and laryngeal cancer cells

Wei Chen, Zhiyi Wang, Junfeng Ji, Tao Shi, Hong ye Jiao, You Cheng, Li Xu, Rui Wang

doi : 10.18632/aging.204356

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Comprehensive analysis of prognostic significance of cadherin (CDH) gene family in breast cancer

Su-Chi Ku, Hsin-Liang Liu, Che-Yu Su, I-Jeng Yeh, Meng-Chi Yen, Gangga Anuraga, Hoang Dang Khoa Ta, Chung-Chieh Chiao, Do Thi Minh Xuan, Fidelia Berenice Prayugo, Wei-Jan Wang, Chih-Yang Wang

doi : 10.18632/aging.204357

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Identification and validation of genetic signature associated with aging in chronic obstructive pulmonary disease

Shanshan Chen, Yuan Zhan, Jinkun Chen, Jixing Wu, Yiya Gu, Qian Huang, Zhesong Deng, Xiaojie Wu, Yongman Lv, Jungang Xie

doi : 10.18632/aging.204358

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Retraction: Exosomal long non-coding RNA UCA1 functions as growth inhibitor in esophageal cancer

Zijiang Zhu, Huilin Wang, Yao Pang, Hongxia Hu, Hongyi Zhang, Wenhao Wang

doi : 10.18632/aging.204366

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