Journal of Cosmetic Dermatology




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Journal of cosmetic dermatology�February 2023 editorial

Michael H. Gold MD

doi : 10.1111/jocd.15659

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Good tolerance of hyaluronic acid filler injections during the COVID-19 pandemic

Michael Naouri MD, Serge Dahan MD, Anne Le Pillouer Prost MD, Phrynée Coutant-Foulc MD, Catherine Raimbault MD, Françoise Cucurella MD, Muriel Creusot MD, Martine Baspeyras MD, Martine Darchy MD, Randa Khallouf MD, Hugues Cartier MD, Isabelle Baratte MD, Magali Dubois MD, Hans Laubach MD, Groupe de Dermatologie Esthétique et Correctrice de la Société Française de Dermatologie (GDEC)

doi : 10.1111/jocd.15482

The aim of our study was to identify and evaluate the complications related to hyaluronic acid during the COVID-19 pandemic.

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Soap or alcohol-based products? The effect of hand hygiene on skin characteristics during the COVID-19 pandemic

Mario Chopin-Doroteo PhD, Edgar Krötzsch PhD

doi : 10.1111/jocd.15523

Different strategies for hand skin hygiene have been used to prevent the spread of SARS-CoV-2. However, frequent hand sanitization has been associated with skin damage. The present study aimed to evaluate hand hygiene habits during the COVID-19 pandemic and the effect of the repetitive use of soap or alcohol-based products on skin characteristics.

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Skin manifestations following anti-COVID-19 vaccination: A multicentricstudy from Turkey

Ilteris Oguz Topal MD, Aslı Tokmak MD, Gökçe Işıl KurmuÅŸ MD, Göknur Kalkan MD, Düriye Deniz Demirseren MD, Mustafa Tosun MD, Selma Emre MD, TuÄŸba Özkök Akbulut MD, Hatice Kaya Özden MD, Mahmut Can Koska MD, Seray Külcü Çakmak MD, Ã–mer Kutlu MD, Emine Mutlu MD, GüneÅŸ Gür Aksoy MD, Filiz TopaloÄŸlu Demir MD, AyÅŸe Serap KaradaÄŸ MD

doi : 10.1111/jocd.15570

After the emergence of the pandemic caused by the COVID-19 virus, vaccination with various vaccines has started to be implemented across the world. To identify dermatological reactions developing after the COVID-19 vaccines administered in Turkey and determine their clinical features and risk factors that may play a role in their development.

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Cutaneous reactions after CoronaVac and BioNTech vaccines

Ümran Öner MD, Akın Aktaş MD

doi : 10.1111/jocd.15573

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Mask-related adverse skin reactions in orientals during COVID-19: Prevalence, social-psychological impacts and risk factors for acne exacerbation

Chen Lujia MD, Zheng Hanlong MD, Shao Hui MD, Tang Jieying MD, Yang Jianmin MD, Li Weiwei MD, PhD

doi : 10.1111/jocd.15593

COVID-19 pandemic has caused mask-related skin problems on health-care professions, yet very few studies have investigated the prevalence in oriental general population.

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Therapeutic application of machine learning in psoriasis: A Prisma systematic review

Snehal Balvant Lunge MD, Nandini Sundar Shetty MD, Vidyadhar R. Sardesai MD, Priyanka Karagaiah MD, Paul S. Yamauchi MD, Jeffrey M. Weinberg MD, Leon Kircik MD, Mario Giulini MD, Mohamad Goldust MD

doi : 10.1111/jocd.15122

Dermatology, being a predominantly visual-based diagnostic field, has found itself to be at the epitome of artificial intelligence (AI)-based advances.

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Targeting SDF-1 as an efficient strategy to resolve skin hyperpigmentation issues with Himanthalia elongata extract

Marie Meunier MS, Marine Bracq BS, Emilie Chapuis BS, Laura Lapierre BS, Anne Humeau PhD, Sylvie Bernard BS, Carole Lambert PhD, Chantal Paulus BS, Pascale Auriol BS, Perrine Lemagnen BS, Jérôme Sandré MD, Daniel Auriol PhD, Amandine Scandolera PhD, Romain Reynaud MS

doi : 10.1111/jocd.15357

During aging, human skin is facing hyperpigmentation disorders: senile lentigo (chronobiologic aging) leads to loss of melanogenesis' control while solar lentigo (UV exposure) promotes an increase of oxidized proteins, melanogenesis, and lipofuscin.

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Adult and juvenile dermatomyositis treatment

Anant Patil MD, Jun Lu MD, FAAD, Martin Kassir MD, Mahsa Babaei MD, Mohamad Goldust MD

doi : 10.1111/jocd.15363

Dermatomyositis is a rare autoimmune inflammatory condition affecting skin and muscles. The disease can be seen in both adults and children. It can be associated with malignancy.

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Clinical update on cutaneous and subcutaneous sarcomas

Jyoti Kumari MBBS, MD, Kinnor Das PGT (MD), Anant Patil MD, Mahsa Babaei MD, Clay J. Cockerell MD, Mohamad Goldust MD

doi : 10.1111/jocd.15369

Cutaneous sarcomas are uncommon cancers that can have a wide range of clinical symptoms and lead to considerable cutaneous as well as systemic morbidity.

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Pentoxifylline in dermatology

Eliza Balazic BS, Eden Axler BS, Hailey Konisky BS, Urmi Khanna MD, Kseniya Kobets MD

doi : 10.1111/jocd.15445

Pentoxifylline was initially marketed for use in patients with intermittent claudication due to chronic occlusive arterial disease of the extremities but has since been shown to have several off-label uses in dermatology.

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Clinical validation of the upper face first principle�A clinical, prospective, interventional split-face study

Claudia A. Hernandez MD, David E. Uribe Zapata MD, Maria Paula Bermudez MD, Konstantin Frank MD, Nicholas Moellhoff MD, Michael Alfertshofer MD, Robert H. Gotkin MD, Kristina Davidovic MD, Sebastian Cotofana MD, PhD, PhD

doi : 10.1111/jocd.15563

Previous clinical and anatomic investigations have identified the clinical relevance of facial biomechanics. Based on this new understanding, principles for facial aesthetic procedures were established: Lateral Face First, Deep Layers First, and Upper Face First.

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Calcium hydroxylapatite microspheres activate fibroblasts through direct contact to stimulate neocollagenesis

Bartosch Nowag PhD, Gabriela Casabona MD, Stefan Kippenberger MD, PhD, Nadja Zöller MD, PhD, Thomas Hengl PhD

doi : 10.1111/jocd.15521

Calcium hydroxylapatite (CaHA; Radiesse, Merz North America) restores volume and stimulates collagen production. The aim of this research was to explore the role of dilution and diffusion in microsphere distribution and the effect of CaHA concentration on activation of fibroblasts to produce collagen.

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Efficacy and safety of hyaluronic acid filler on the treatment of horizontal neck lines

Awika Rongthong MD, MSc, Rungsima Wanitphakdeedecha MD, MA, MSc, Mart Maiprasert MD, Kathryn Anne Guico Cembrano MD, MBA, Nataya Voravutinon MD, Sarawalai Rakchart MD, MSc, Kanchana Sermswan MD, Pongsiri Koonngam MD

doi : 10.1111/jocd.15539

Injection of hyaluronic acid fillers (HA) fillers for horizontal neck line correction and rejuvenation has gained popularity in recent years despite conflicting reports on its efficacy and safety.

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Filler-based correction of tear trough depressions and eye bags in Japanese patients: A classification system and treatment algorithm

Kiyoko Kato MD, Tomoe Kajiwara MD, Nobutaka Furuyama MD PhD, Steven Liew MD FRACS

doi : 10.1111/jocd.15449

Tear trough depressions are widely treated with fillers. However, it is questionable whether the same strategies can always be used for Caucasian and Japanese patients, owing to differences in bone and skin structures and epithelial thickness.

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Efficacy of injecting hybrid cooperative complexes of hyaluronic acid for the treatment of vulvar lichen sclerosus: A preliminary study

Marinella Tedesco MD, Valentina Garelli MD, Fulvia Elia MD, Francesca Sperati, F. Biondi, L. Mosiello, Aldo Morrone MD, Emilia Migliano MD

doi : 10.1111/jocd.14896

Lichen sclerosus is a chronic relapsing inflammatory skin disease, which involves most commonly the anogenital region. The gold standard in treatment is ultra-potent topical steroids (clobetasol propionate): it aims at controlling the symptoms, stopping further scarring and distortion, and reducing the risk of cancer.

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No association found between late-onset inflammatory adverse events after soft tissue filler injections and the adaptive immune system

Tom S. Decates MD, PhD, Peter J. Velthuis MD, PhD, Renushka Jhingoerie MSc, Susan Gibbs MD, PhD, Yara Bachour MD, PhD, Frank B. Niessen MD, PhD

doi : 10.1111/jocd.15098

To date, it is unknown why some individuals develop late-onset inflammatory adverse events after treatment with fillers. These events may result from various factors, including an immunological response of the adaptive immune system.

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A prospective multicenter clinical trial evaluating the efficacy and safety of a hyaluronic acid-based filler with Tri-Hyal technology in the treatment of lips and the perioral area

Agnès Ehlinger-David MD, Mihai Gorj MD, Frédéric Braccini MD, Federico Loreto MD, Anne Grand-Vincent MD, Philippe Garcia MD, Maryna Taieb MD, Laurent Benadiba MD, Isabelle Catoni MD, Elena Rumyantseva Mathey MD, Jean-Jacques Deutsch MD, Philippe Bahadoran MD, Thibaud Vincent MD, Michel David MD, Hugues Cartier MD, Karim Nadra PhD, Nicholas Moellhoff MD, Ferial Fanian MD, PhD

doi : 10.1111/jocd.15169

Age-related changes of facial soft tissue cause clinical signs of facial aging such as lip atrophy, marionette lines, and an accentuated nasolabial fold. These changes can be modified using dermal fillers.

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Comparative clinical study for the efficacy and safety of two different hyaluronic acid-based fillers with Tri-Hyal versus Vycross technology: A long-term prospective randomized clinical trial

Frederic Braccini MD, Ferial Fanian MD, PhD, Philippe Garcia MD, Henry Delmar MD, Federico Loreto MD, Laurent Benadiba MD, Karim Nadra PhD, Philippe Kestemont MD

doi : 10.1111/jocd.15200

Hyaluronic acid-based fillers have an immediate volumizing effect for the treatment of dermal contour deformities and to smooth dermal depressions formed by the loss of volume. A previous study on 2016–2018 has shown the efficacy and safety of the HA-based filler ART FILLER® Volume on the midface only, but not in a comparative manner.

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Selective photothermolysis with a novel 1726 nm laser beam: A safe and effective solution for acne vulgaris

David Goldberg MD, FAAD, Amogh Kothare MS, Margot Doucette BSc, Arshdeep Kaur MS, Stephen Ronan MD, Jeffrey Fromowitz MD, FAAD, Amer Hamidi-Sakr PhD

doi : 10.1111/jocd.15602

Selective photothermolysis on sebaceous glands is an effective method for treating acne vulgaris (AV); however, safety, efficacy, and discomfort hinder its utilization in clinical settings.

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Efficiency and safety of microneedling fractional radiofrequency in the treatment of Chinese atrophic acne scars: A retrospective study of 3 consecutive treatments with 1-month intervals

Linting Huang MD, PhD, Yang Liu MD, Wei Fang MD, PhD, Lanjun Liu BN, Qilin Sun MD, Xiaoxi Lin MD, PhD, Hui Xu MD, PhD, Yali Yang MD, PhD

doi : 10.1111/jocd.15454

Atrophic acne scars (AAS) impact the aesthetic appearance, inducing social and psychological problems. Effective and safe therapy for AAS is urgently needed now. Microneedling fractional radiofrequency (MFRF) has emerged as a minimal invasive alteration for treating AAS lately, while the existing data on Chinese population was few.

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Low-energy green light alleviates senescence-like phenotypes in a cell model of photoaging

Chuanlong Jia MD, Chengchen Gong MD, Yongzhou Lu MD, Nan Xu PhD

doi : 10.1111/jocd.15175

Ultraviolet B (UVB) affects diverse pathways in skin cells, resulting in skin photoaging. Skin fibroblasts internalize and degrade elastin and collagen, playing prominent roles in photoaging.

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Comparison of the efficacy of carboxytherapy versus fractional CO2 laser therapy for the treatment of periorbital dark circles: A randomized clinical trial

Hooman Zaheri MD, Amir Mohammad Beyzaee MD, Ghasem Rahmatpour Rokni MD, Anant Patil MD, Masoud Golpour MD, Mohamad Goldust MD

doi : 10.1111/jocd.15337

Periorbital dark circles (PDC) is one of the most common cosmetic issues in today's society. Only moderate degree of improvement has been achieved by various available treatment options. The present study aimed to compare the clinical efficacy of carboxytherapy and fractional CO2 laser therapy in the management of PDC.

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Efficacy and safety of a new peeling formulated with a pool of PHAs for the treatment of all skin types, even sensitive

Giulia Gentili D, Paola Perugini PhD, Stefano Bugliaro, Camilla D'Antonio D

doi : 10.1111/jocd.15215

Actually, the use of chemical peels in cosmetics and dermatology continues to grow due to their versatility, clinical endpoint–directed predictability, and favorable risk profile in comparison to lasers.

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Efficacy of Jessener solution versus intralesional steroid in treatment of alopecia areata

Ahmed Rashad Elshahid MD, Ahmed Said Kadah MD, Eman Abdellatif Hassan MBBCh, Mohamed L. Elsaie MD

doi : 10.1111/jocd.15546

Alopecia areata is an autoimmune condition that causes non-scarring hair loss. To date, there is no single cure and treatment remains challenging.

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Simvastatin cream alleviates dermal fibrosis in a rabbit ear hypertrophic scar model

David Dolivo PhD, Adrian Rodrigues MD, Lauren Sun BA, Chun Hou MD, Yingxing Li BS, Eugene Chung BS, Kai Leung PhD, Robert Galiano MD, Thomas Mustoe MD, Seok Jong Hong PhD

doi : 10.1111/jocd.15142

Hypertrophic scars (HTS) result from injury to the skin and represent a clinical burden with limited treatment options. Previously, we demonstrated that statin drugs could attenuate HTS formation, but convenient topical delivery and retention of these drugs at the wound site remains a challenge.

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The medieval skincare routine according to the formulations of Madgistra Trotula and the Medical School of Salerno and its reflection on cosmetology of the third millennium

Simona Pisanti PhD, Teresa Mencherini PhD, Tiziana Esposito PhD, Valeria D'Amato PhD, Tania Re PsyD, Maurizio Bifulco MD, Rita P. Aquino PHARMD

doi : 10.1111/jocd.15234

Officinal plants, minerals, animal derivatives, and miscellaneous have always been used to treat and improve appearance despite the different aesthetic canons of a specific historical and cultural context.

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Once again on the Empress Zoe: Women, dermatology, cosmetics, and materia medica (medical matter) in the ancient world

Marco Cilione PhD, Berenice Cavarra PhD, Valentina Gazzaniga PhD

doi : 10.1111/jocd.15239

An article published in 2012 in the Journal of Cosmetic Dermatology discussed the historical sources presenting the Byzantine Empress Zoe Porphyrogenita as an expert in cosmetic and pharmacological remedies that could give their users a youthful appearance and a kind of eternal youth.

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Efficacy and safety of silymarin containing antioxidant serum as an adjuvant treatment of mild-to-moderate acne vulgaris: A prospective, open-label pilot study

Jemin Kim MD, Yun Na Lee BS, Joohee Lee MD, Sang Gyu Lee MS, Hyun Kim BSN, Ye Seul Choi BS, Zoe Diana Draelos MD, Jihee Kim MD, PhD

doi : 10.1111/jocd.15439

Silymarin is the active component of milk thistle, which has antioxidant properties by scavenging free radicals and potential comedolytic properties.

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Therapeutic efficacy of metronidazole by needle-free jet injection combined with blue light therapy in Moderate-to-Severe facial acne vulgaris

Lu Yi MM, Lihua Gao PhD, Lv Lv MD, Bo Zhang MM, Fangru Chen MD, Fengyuan Yang MB, Wenjie Yan MM, Lijun Jiang MB, Nianzhen Li MB, Yuanqing Lao MB, Jianyun Lu MD, Xi Huang MD

doi : 10.1111/jocd.15442

Acne vulgaris is one of the most common dermatological diseases. Some topical treatments for acne used in combination, such as blue light and topical antibiotics (such as metronidazole) by needle-free jet injection (NFJI), are becoming prevalent in clinical practice, but the efficacy remains uncertain.

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Efficacy of the continuous use of a lotion with carbon dioxide on male subjects with mild acne

Aiko Kiyozuka MS, Asami Kajiyama MS, Rie Ootsuki PhD, Masaru Hosokawa MS, Masahiro Miyaki MS, Yutaka Takagi PhD

doi : 10.1111/jocd.15456

Acne vulgaris is caused by dyslipidemia, dyskeratosis and/or abnormal bacterial growth. The obstruction of skin pores due to hyperkeratosis of the infundibulum contributes to the formation of comedones.

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Alopecia areata and pattern hair loss (androgenetic alopecia) on social media – Current public interest trends and cross-sectional analysis of YouTube and TikTok contents

Aditya K. Gupta MD, PhD, Shruthi Polla Ravi MESc, Tong Wang MSc

doi : 10.1111/jocd.15605

With an ever-growing influence of social media in healthcare, concurrent with increased emphasis on patient autonomy and shared decision-making, dermatologists treating hair loss need to be cognizant of online interest trends and the types of information disseminated across popular platforms.

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Aesthetic considerations when treating the Latin American patient: Thriving in diversity international roundtable series

Sabrina Guillen Fabi MD, FAAD, FAACS, Claudia Hernandez MD, José Raúl Montes MD, Sebastian Cotofana MD, Steve Dayan MD

doi : 10.1111/jocd.15516

The Hispanic/Latin American population is the fastest growing non-Caucasian group in the United States. Within this group, demand for aesthetic procedures is on the rise.

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Evaluating the combined efficacy of oral isotretinoin and topical tacrolimus versus oral finasteride and topical tacrolimus in frontal fibrosing alopecia�A randomized controlled trial

Ghasem Rahmatpour Rokni MD, Seyed Naser Emadi MD, Abbas Dabbaghzade MD, Neda Jahantigh MD, Amir Mohammad Beyzaee MD, Aseem Sharma MD, Lidia Rudnicka MD, Mohamad Goldust MD

doi : 10.1111/jocd.15232

Treatment of frontal fibrosing alopecia (FFA) is complicated and challenging. In this study, we evaluated the efficacy of combining topical tacrolimus with isotretinoin versus finasteride in patients with FFA.

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Impact of defensins-containing body cream on skin composition

Michael Eggerstedt MD, Solymar Torres-Maldonado MD, Arman Danielian MD, Song Hon Josh Hwang MD, Kristen A. Echanique MD

doi : 10.1111/jocd.15118

Defensins are peptides capable of reactivating latent LGR6 stem cells in the basal layer. When applied topically, these peptides can reduce signs of skin aging and increase dermal thickness. This study investigates the effects of a topical defensin formulation on extremity skin composition.

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Content and stability of B complex vitamins in commercial cosmetic products

Žane Temova Rakuša PhD, Anja Šenk BS, Robert Roškar PhD

doi : 10.1111/jocd.15321

Individual B vitamins have many favorable effects on the skin and are common cosmetic ingredients. However, their formulation is demanding due to stability issues, which consequently affect the products’ quality.

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Ligularia fischeri ethanol extract: An inhibitor of alpha-melanocyte-stimulating hormone-stimulated melanogenesis in B16F10 melanoma cells

In-Hwan Joo PhD, Ji-Hee Choi MS, Dong-Hee Kim PhD, Moon-Jung Chung PhD, Mi-Hye Lim PhD

doi : 10.1111/jocd.15335

Ligularia fischeri is a perennial herb isolated from plants of the Asteraceae family. Ligularia fischeri is distributed throughout Korea, Japan, eastern Siberia, and China.

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Serum zinc-alpha-2 glycoprotein and insulin levels and their correlation with metabolic syndrome in patients with rosacea

Rana Basara Sahin MD, Fatma Arzu Kilic MD, Pelin Hizli MD, Ozgur Baykan MD

doi : 10.1111/jocd.15447

Metabolic syndrome and insulin resistance may accompany rosacea. Zinc-alpha-2 glycoprotein (ZAG) is an adipokine involved in lipid, glucose, and insulin metabolism and might be associated with metabolic syndrome and insulin resistance.

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The moisturizing effect of Capparis spinosa fruit extract targeting filaggrin synthesis and degradation

Yina Lu MSc, Wenhuan Zhang MSc, Lidan Zhou MSc, Yue Xiong BSc, Qing Liu PhD, Xuemei Shi BSc, Jun Tian MSc

doi : 10.1111/jocd.15461

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Endothelial–mesenchymal transition as a novel mechanism for generating myofibroblasts during wound healing and scarring

Ling Guo MD, Jun-wei Mi MD, Hua-cai Zhang MD, Jie Gao PhD, Shu Zhang BD, Luo-xi Li MD, Meng-yu Wu MD, Jian-min Wang PhD, Hong Huang PhD

doi : 10.1111/jocd.15466

The endothelial–mesenchymal transition (EndMT) is an important mechanism in tissue regeneration and the development of organ fibrosis. Whether EndMT occurs in wound healing and scarring remains unknown.

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Hairfluencer social media trends every dermatologist should know in 2021

Briana Paiewonsky BS, Nicole Heinen BS, Maria Hordinsky MD, Neil Sadick MD, Ronda S. Farah MD

doi : 10.1111/jocd.15123

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Efficacy and safety of photothermal-bioactivated platelet-rich plasma for facial rejuvenation

Beatriz Beltrán MD, Manuel Antonio Rubio Sánchez MD, Graciela Melamed MD, Hernán Pinto PhD, MD

doi : 10.1111/jocd.15250

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UV safety recommendations and health claims by U.S. tanning salon operators in a nationally representative sample

Kayley L. Erickson BS, Cong Fan BA, Sarah J. Eley BS, Annalise Vaccarello BS, James R. Xu BS, Steve W. Gendi BS, Jeremy S. Bordeaux MD, MPH

doi : 10.1111/jocd.15288

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Teledermatology in the management of hidradenitis suppurativa: Should we improve this service?

Angelo Ruggiero MD, Claudio Marasca MD, Gabriella Fabbrocini PROF-MD, Alessia Villani MD, Fabrizio Martora MD

doi : 10.1111/jocd.15292

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Impact of Sars-CoV-2 pandemic on psoriatic patients

Gabriele Biondi MD, Giovanni Sotgiu MD, Giovanni Cicalò MS, Federica Sucato MD, Rosanna Satta MD, Maria Antonietta Montesu MD

doi : 10.1111/jocd.15307

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A case of linear psoriasis in a young patient with Down syndrome and review of the literature

Fabrizio Martora MD, Gabriella Fabbrocini MD, Vincenzo Picone MD, Chiara Blasio MD, Angelo Ruggiero MD, Matteo Megna MD

doi : 10.1111/jocd.15317

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“PiMa sign�: A possible correlation between dermographism and pityriasis versicolor?

Fabrizio Martora MD, Lucia Gallo MD, Gabriella Fabbrocini MD, Vincenzo Picone MD

doi : 10.1111/jocd.15345

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Hair removal and deodorants in hidradenitis suppurativa: An online survey on patients' habits

Wanda Lauro MD, Gianmarco Capasso MD, Gabriella Fabbrocini MD, Claudio Marasca MD

doi : 10.1111/jocd.15373

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A 6-year-old girl with hemangioma with hearing loss in right ear

RiGa Wu MD, Lu Yu MD, Li Li MD, Lin Ma MD

doi : 10.1111/jocd.15405

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Metaverse in diagnosis of skin diseases

Jyoti Kumari MBBS, MD, Kinnor Das MD, Mohamad Goldust MD

doi : 10.1111/jocd.15409

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Gua-sha, Jade Roller, and Facial Massage: Are there benefits within dermatology?

Austin Hamp DO, Jarett Anderson DO, Melissa R. Laughter MD, PhD, Jaclyn B. Anderson MD, Colby L. Presley DO, Chandler W. Rundle MD, Robert P. Dellavalle MD, PhD, MSPH

doi : 10.1111/jocd.15421

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Integrating artificial intelligence and telehealth services in psychodermatology

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doi : 10.1111/jocd.15435

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Niacinamide + “Linefade� ameliorate crow's feet wrinkles and facial sagging in a split-face image analysis study

George P. Majewski BSc, Paolo Marchesi MChem, Krzysztof Bojanowski PhD

doi : 10.1111/jocd.15459

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An innovative technique for thread-lifting the neck using a nonbarbed nylon suture

Nicolas Zubrzycki, Liang Joo Leow

doi : 10.1111/jocd.15325

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Comparison of the efficacy and safety of a picosecond frequency-doubled 532-nm Nd:YAG Laser and a Q-switched frequency-doubled 532-nm Nd:YAG Laser for the treatment of ephelides: A randomized, split-lesion, double-center, controlled trial

Yin Yang MD, PhD, Zhikuan Xia MD, PhD, Lifang Guo MD, PhD, Qiuju Wu MD, Mengli Zhang MD, PhD, Rong Zeng MD, PhD, Yuxi An MD, Yitong Xie MD, Wei Wei MD, Yiping Ge MD, PhD, Rongya Yang MD, PhD, Tong Lin MD, PhD

doi : 10.1111/jocd.15462

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Combination of CO2 laser therapy and pulsed dye laser therapy for the treatment of actinic cheilitis

Giulio Cortonesi, Carolina Donelli, Corinne Orsini, Ivana Guidi, Pietro Rubegni, Emanuele Trovato

doi : 10.1111/jocd.15494

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