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The foundation and the four pillars of treatment for cardiorenal protection in people with chronic kidney disease and type 2 diabetes
Rajiv Agarwal, Denis Fouque
doi : 10.1093/ndt/gfac331
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 253–257
The new guidelines of the European Association of Urology on Urolithiasis: the urology–nephrology intersection
Giovanni Gambaro, Lazaros Tzelves, Andreas Skolarikos, Mehmet Kanbay, Alberto Ortiz, Mario Cozzolino
doi : 10.1093/ndt/gfac309
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 258–260
Dendrin in IgA nephropathy: protective or marker of early disease?
Rosanna Coppo, Fernando C Fervenza
doi : 10.1093/ndt/gfac258
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 261–263
The role of blood pressure control in the prevention of cardiorenal disease in patients with chronic kidney disease
George Bonifant, Matthew R Weir
doi : 10.1093/ndt/gfac313
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 264–270
Clinical and genetic spectra of autosomal dominant tubulointerstitial kidney disease
Holly Mabillard, John A Sayer, Eric Olinger
doi : 10.1093/ndt/gfab268
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 271–282
Autosomal dominant tubulointerstitial kidney disease (ADTKD) is a clinical entity defined by interstitial fibrosis with tubular damage, bland urinalysis and progressive kidney disease.
Membranoproliferative glomerulonephritis: no longer the same disease and may need very different treatment
Marina Noris, Erica Daina, Giuseppe Remuzzi
doi : 10.1093/ndt/gfab281
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 283–290
Membranoproliferative glomerulonephritis (MPGN) is a pattern of glomerular injury that may be primary or secondary to infections, autoimmune diseases and haematological disorders. Primary C3G and IC-MPGN are rare and the prognosis is unfavourable.
Seizures in patients with kidney diseases: a neglected problem?
Ozkan Gungor, Zeki Aydin, Ayca Inci, Ebru Gok Oguz, Mustafa Arici
doi : 10.1093/ndt/gfab283
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 291–299
Nephrologists may encounter many systemic problems in their patients, including involvement of the neurological system and the development of seizures.
Kidney transplantation during mass disasters—from COVID-19 to other catastrophes: a Consensus Statement by the DESCARTES Working Group and Ethics Committee of the ERA
Mehmet Sukru Sever, Raymond Vanholder, Gabriel Oniscu, Daniel Abramowicz, Wim Van Biesen, Umberto Maggiore, Bruno Watschinger, Christophe Mariat, Jadranka Buturovic-Ponikvar, Marta Crespo, Geir Mjoen, Peter Heering, Licia Peruzzi, Ilaria Gandolfini, Rachel Hellemans, Luuk Hilbrands
doi : 10.1093/ndt/gfac251
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 300–308
Mass disasters are characterized by a disparity between healthcare demand and supply, which hampers complex therapies like kidney transplantation.
Can early, tight glycaemic control prevent post-transplant diabetes mellitus?
Yassine Laghrib, Christophe De Block, Daniel Abramowicz, Rachel Hellemans
doi : 10.1093/ndt/gfac129
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 309–310
The role of dendrin in IgA nephropathy
Anna Levin, Angelina Schwarz, Jenny Hulkko, Liqun He, Ying Sun, Peter Barany, Annette Bruchfeld, Maria Herthelius, Lars Wennberg, Kerstin Ebefors, Jaakko Patrakka, Christer Betsholtz, Jenny Nyström, Johan Mölne, Kjell Hultenby, Anna Witasp, Annika Wernerson
doi : 10.1093/ndt/gfac208
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 311–321
Immunoglobulin A nephropathy (IgAN) and its systemic variant IgA vasculitis (IgAV) damage the glomeruli, resulting in proteinuria, hematuria and kidney impairment.
The direct effect of fibroblast growth factor 23 on vascular smooth muscle cell phenotype and function
Noemi Vergara, M Victoria Pendón-Ruiz de Mier, Cristian Rodelo-Haad, Gonzalo Revilla-González, Cristina Membrives, Juan M DÃaz-Tocados, Julio M MartÃnez-Moreno, Ana I Torralbo, Carmen Herencia, MarÃa Encarnación RodrÃguez-Ortiz, Rodrigo López-Baltanás, Williams G Richards, Arnold Felsenfeld, Yolanda Almadén, Alejandro Martin-Malo, Juan Ureña, Rafael SantamarÃa, Sagrario Soriano, Mariano RodrÃguez, Juan R Muñoz-Castañeda
doi : 10.1093/ndt/gfac220
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 322–343
In chronic kidney disease (CKD) patients, increased levels of fibroblast growth factor 23 (FGF23) are associated with cardiovascular mortality.
Effect of lanthanum carbonate on serum calciprotein particles in patients with stage 3–4 CKD—results from a placebo-controlled randomized trial
Mark K Tiong, Edward R Smith, Elaine M Pascoe, Grahame J Elder, Nicole M Lioufas, Eugenia Pedagogos, Carmel M Hawley, Andrea Valks, Stephen G Holt, Tim D Hewitson, Nigel D Toussaint
doi : 10.1093/ndt/gfac043
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 344–351,
Calciprotein particles (CPP) are colloidal aggregates of calcium phosphate and the mineral-binding protein fetuin-A, and are potential mediators of cardiovascular disease in chronic kidney disease (CKD).
Development and validation of a deep neural network–based model to predict acute kidney injury following intravenous administration of iodinated contrast media in hospitalized patients with chronic kidney disease: a multicohort analysis
Ping Yan, Shao-Bin Duan, Xiao-Qin Luo, Ning-Ya Zhang, Ying-Hao Deng
doi : 10.1093/ndt/gfac049
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 352–361
Stratification of chronic kidney disease (CKD) patients [estimated glomerular filtration rate (eGFR) <60Â mL/min/1.73 m2] at risk for post-contrast acute kidney injury (PC-AKI) following intravenous administration of iodinated contrast media (ICM) is important for clinical decision-making and clinical trial enrollment.
Proposal for individualized dosing of eculizumab in atypical haemolytic uraemic syndrome: patient friendly and cost-effective
Mendy ter Avest, Romy N Bouwmeester, Caroline Duineveld, Kioa L Wijnsma, Elena B Volokhina, Lambertus P W J van den Heuvel, David M Burger, Jack F M Wetzels, Nicole C A J van de Kar, Rob ter Heine, CUREiHUS study group
doi : 10.1093/ndt/gfac056
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 362–371
Eculizumab is a lifesaving yet expensive drug for atypical haemolytic uraemic syndrome (aHUS). Current guidelines advise a fixed-dosing schedule, which can be suboptimal and inflexible in the individual patient.
Kidney outcomes with finerenone: an analysis from the FIGARO-DKD study
Luis M Ruilope, Bertram Pitt, Stefan D Anker, Peter Rossing, Csaba P Kovesdy, Roberto Pecoits-Filho, Pablo Pergola, Amer Joseph, Andrea Lage, Nicole Mentenich, Markus F Scheerer, George L Bakris
doi : 10.1093/ndt/gfac157
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 372–383
In FIGARO-DKD, finerenone reduced the risk of cardiovascular events in patients with type 2 diabetes (T2D) and stage 1–4 chronic kidney disease (CKD).
Biopsy-proven CKD etiology and outcomes: the Chronic Kidney Disease Japan Cohort (CKD-JAC) study
Takayuki Hamano, Takahiro Imaizumi, Takeshi Hasegawa, Naohiko Fujii, Hirotaka Komaba, Masahiko Ando, Masaomi Nangaku, Kosaku Nitta, Hideki Hirakata, Yoshitaka Isaka, Takashi Wada, Shoichi Maruyama, Masafumi Fukagawa
doi : 10.1093/ndt/gfac134
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 384–395,
The Kidney Disease: Improving Global Outcomes guidelines advocate the cause–glomerular filtration rate (GFR)–albuminuria (CGA) classification for predicting outcomes. However, there is a dearth of data supporting the use of the cause of chronic kidney disease.
EXT1 and NCAM1-associated membranous lupus nephritis in a cohort of patients undergoing repeat kidney biopsies
Paul P Miller, Tiffany Caza, Christopher P Larsen, Vivek Charu
doi : 10.1093/ndt/gfac058
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 396–404
Exostosin 1/2 (EXT1/2) and neural cell adhesion molecule 1 (NCAM1) associated membranous lupus nephritis (MLN) may represent distinct disease phenotypes with prognostic significance.
Survival, symptoms and hospitalization of older patients with advanced chronic kidney disease managed without dialysis
Angela Chou, Chenlei Li, Sanjay Farshid, Anna Hoffman, Mark Brown
doi : 10.1093/ndt/gfac154
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 405–413
Shared decision-making (SDM) is important when considering whether an older patient with advanced chronic kidney disease (CKD) should be managed with dialysis or conservative kidney management (CKM).
Eculizumab for paediatric patients with atypical haemolytic uraemic syndrome: full dataset analysis of post-marketing surveillance in Japan
Shuichi Ito, Hiroshi Hataya, Akira Ashida, Riku Hamada, Tomoaki Ishikawa, Yumiko Ishikawa, Akihiko Shimono, Takao Konomoto, Tomoki Miyazawa, Masao Ogura, Kazuki Tanaka, Shoji Kagami
doi : 10.1093/ndt/gfac150
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 414–424
Eculizumab was approved for atypical haemolytic uraemic syndrome (aHUS) in Japan in 2013.
Bone density, microarchitecture and estimated strength in stone formers: a cross-sectional HR-pQCT study
Priscila Ligeiro Gonçalves Esper, Fernanda Guedes Rodrigues, Thalita Lima Melo, Milene Subtil Ormanji, Carlos M Campos, Jackeline Couto Alvarenga, Valeria de Falco Caparbo, Aluizio Barbosa Carvalho, Rosa Maria Rodrigues Pereira, Ita Pfeferman Heilberg
doi : 10.1093/ndt/gfac128
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 425–434
Low areal bone mineral density (BMD), increased fracture risk and altered bone remodeling have been described among stone formers (SFs), but the magnitude of these findings differs by age, sex, menopausal status and urinary calcium (uCa).
Impact of incremental initiation of haemodialysis on mortality: a systematic review and meta-analysis
Emma Caton, Shivani Sharma, Enric Vilar, Kenneth Farrington
doi : 10.1093/ndt/gfac274
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 435–446
Incremental haemodialysis initiation entails lower sessional duration and/or frequency than the standard 4 h thrice-weekly approach. Dialysis dose is increased as residual kidney function (RKF) declines. This systematic review evaluates its safety, efficacy and cost-effectiveness.
A real world comparison of HepB (Engerix-B®) and HepB-CpG (Heplisav-B®) vaccine seroprotection in patients receiving maintenance dialysis
Harold J Manley, Gideon Aweh, Jill Frament, Vladimir Ladik, Eduardo K Lacson, Jr
doi : 10.1093/ndt/gfac039
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 447–454
Vaccination against hepatitis B virus (HBV) is recommended for dialysis patients.
Comparison of the association between six different frailty scales and clinical events in patients on hemodialysis
Keigo Imamura, Shohei Yamamoto, Yuta Suzuki, Shun Yoshikoshi, Manae Harada, Shiwori Osada, Kentaro Kamiya, Ryota Matsuzawa, Atsuhiko Matsunaga
doi : 10.1093/ndt/gfac047
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 455–462
Frailty is associated with adverse outcomes in patients undergoing hemodialysis (HD). However, no study has used various frailty assessments in patients on HD to examine their association with clinical events. In this study, we investigated the association between clinical events and six frailty scales.
Impact of previous REnal TRansplantation on the mid-term renal Outcome after CARdiac surgery: the RETROCAR trial
Antoine Beurton, Antoine Fajardie, Sebastien Rubin, Pierre Belnou, Clement Aguerreche, Mathieu Pernot, Stefano Mion, Julien Imbault, Alexandre Ouattara
doi : 10.1093/ndt/gfac269
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 463–471
Acute kidney injury (AKI) is one of the most common complications after cardiac surgery with cardiopulmonary bypass (CPB). Renal transplant recipients (RTRs) have a higher risk of cardiac surgery–associated AKI (CSA-AKI).
Retrospective analysis of the impact of severe obesity on kidney transplant outcomes
Demetra Tsapepas, Vanessa Sandra, Leigh Ann Dale, Yelena Drexler, Kristen L King, Miko Yu, Katherine Toma, Jennifer Van Bever, Navin Sanichar, S Ali Husain, Sumit Mohan
doi : 10.1093/ndt/gfac169
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 472–480
The prevalence of obesity among kidney transplant recipients is rising. We sought to determine the association between recipient body mass index (BMI) and post-transplant complications.
Belatacept rescue conversion in kidney transplant recipients with vascular lesions (Banff cv score >2):  a retrospective cohort study
Dominique Bertrand, Marie Matignon, Antoine Morel, Lebourg Ludivine, Mathilde Lemoine, Mélanie Hanoy, Frank Le Roy, Dorian Nezam, Mouad Hamzaoui, Tristan de Nattes, Anissa Moktefi, Arnaud François, Charlotte Laurent, Isabelle Etienne, Dominique Guerrot
doi : 10.1093/ndt/gfac178
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 481–490
Immunosuppression in kidney transplant recipients with decreased graft function and histological vascular changes can be particularly challenging. The impact of a late rescue conversion to belatacept on kidney graft survival in this context has never been studied.
Long-term cognitive impairments in kidney transplant recipients: impact on participation and quality of life
Aaltje L Ziengs, Anne M Buunk, Lisanne van Sonderen, Michele F Eisenga, Antonio W Gomes Neto, Coby Annema, Thialda Vlagsma, Gerjan J Navis, Stefan P Berger, Stephan J L Bakker, Jacoba M Spikman
doi : 10.1093/ndt/gfac035
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 491–498
Cognitive impairment is often present shortly after transplantation in kidney transplant recipients (KTR). To date, it is unknown whether these impairments persist in the
De novo major cardiovascular events in kidney transplant recipients: a comparative matched cohort study
Ji Eun Kim, Jina Park, Sehoon Park, Mi-yeon Yu, Seon Ha Baek, Sang Hyun Park, Kyungdo Han, Yong Chul Kim, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo, Yon Su Kim, Hajeong Lee
doi : 10.1093/ndt/gfac144
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 499–506,
Although cardiovascular disease is known to be one of the leading causes of death after kidney transplantation (KT), evidence on the risk difference of de novo major adverse cardiovascular events (MACEs) in kidney transplant recipients (KTRs) compared with that in dialysis patients or the general population (GP) remains rare.
Risk of end-stage kidney disease in kidney transplant recipients versus patients with native chronic kidney disease: multicentre unmatched and propensity-score matched analyses
Luca De Nicola, Raffaele Serra, Michele Provenzano, Roberto Minutolo, Ashour Michael, Nicola Ielapi, Stefano Federico, Rosa Carrano, Vincenzo Bellizzi, Carlo Garofalo, Carmela Iodice, Silvio Borrelli, Giuseppe Grandaliano, Giovanni Stallone, Loreto Gesualdo, Paolo Chiodini, Michele Andreucci
doi : 10.1093/ndt/gfac131
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 507–516
In kidney transplant recipients (KTR), the end-stage kidney disease (ESKD) risk dependent on the risk factors acting in native chronic kidney disease (CKD) remains undefined.
Isolated kidney transplantation under lumasiran therapy in primary hyperoxaluria type 1: a report of five cases
Anne-Laure Sellier-Leclerc, Elisabeth Metry, Stéphanie Clave, Peggy Perrin, Cécile Acquaviva-Bourdain, Charlène Levi, Meindert Crop, Sophie Caillard, Bruno Moulin, Jaap Groothoff, Justine Bacchetta
doi : 10.1093/ndt/gfac295
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 517–521
The foundation and the four pillars of treatment for cardiorenal protection in people with chronic kidney disease and type 2 diabetes
Rajiv Agarwal, Denis Fouque
doi : 10.1093/ndt/gfac331
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 253–257
The new guidelines of the European Association of Urology on Urolithiasis: the urology–nephrology intersection
Giovanni Gambaro, Lazaros Tzelves, Andreas Skolarikos, Mehmet Kanbay, Alberto Ortiz, Mario Cozzolino
doi : 10.1093/ndt/gfac309
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 258–260
Dendrin in IgA nephropathy: protective or marker of early disease?
Rosanna Coppo, Fernando C Fervenza
doi : 10.1093/ndt/gfac258
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 261–263
The role of blood pressure control in the prevention of cardiorenal disease in patients with chronic kidney disease
George Bonifant, Matthew R Weir
doi : 10.1093/ndt/gfac313
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 264–270
Clinical and genetic spectra of autosomal dominant tubulointerstitial kidney disease
Holly Mabillard, John A Sayer, Eric Olinger
doi : 10.1093/ndt/gfab268
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 271–282
Autosomal dominant tubulointerstitial kidney disease (ADTKD) is a clinical entity defined by interstitial fibrosis with tubular damage, bland urinalysis and progressive kidney disease.
Membranoproliferative glomerulonephritis: no longer the same disease and may need very different treatment
Marina Noris, Erica Daina, Giuseppe Remuzzi
doi : 10.1093/ndt/gfab281
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 283–290
Membranoproliferative glomerulonephritis (MPGN) is a pattern of glomerular injury that may be primary or secondary to infections, autoimmune diseases and haematological disorders. Primary C3G and IC-MPGN are rare and the prognosis is unfavourable.
Seizures in patients with kidney diseases: a neglected problem?
Ozkan Gungor, Zeki Aydin, Ayca Inci, Ebru Gok Oguz, Mustafa Arici
doi : 10.1093/ndt/gfab283
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 291–299
Nephrologists may encounter many systemic problems in their patients, including involvement of the neurological system and the development of seizures.
Kidney transplantation during mass disasters—from COVID-19 to other catastrophes: a Consensus Statement by the DESCARTES Working Group and Ethics Committee of the ERA
Mehmet Sukru Sever, Raymond Vanholder, Gabriel Oniscu, Daniel Abramowicz, Wim Van Biesen, Umberto Maggiore, Bruno Watschinger, Christophe Mariat, Jadranka Buturovic-Ponikvar, Marta Crespo, Geir Mjoen, Peter Heering, Licia Peruzzi, Ilaria Gandolfini, Rachel Hellemans, Luuk Hilbrands
doi : 10.1093/ndt/gfac251
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 300–308
Mass disasters are characterized by a disparity between healthcare demand and supply, which hampers complex therapies like kidney transplantation.
Can early, tight glycaemic control prevent post-transplant diabetes mellitus?
Yassine Laghrib, Christophe De Block, Daniel Abramowicz, Rachel Hellemans
doi : 10.1093/ndt/gfac129
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 309–310
The role of dendrin in IgA nephropathy
Anna Levin, Angelina Schwarz, Jenny Hulkko, Liqun He, Ying Sun, Peter Barany, Annette Bruchfeld, Maria Herthelius, Lars Wennberg, Kerstin Ebefors, Jaakko Patrakka, Christer Betsholtz, Jenny Nyström, Johan Mölne, Kjell Hultenby, Anna Witasp, Annika Wernerson
doi : 10.1093/ndt/gfac208
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 311–321
Immunoglobulin A nephropathy (IgAN) and its systemic variant IgA vasculitis (IgAV) damage the glomeruli, resulting in proteinuria, hematuria and kidney impairment.
The direct effect of fibroblast growth factor 23 on vascular smooth muscle cell phenotype and function
Noemi Vergara, M Victoria Pendón-Ruiz de Mier, Cristian Rodelo-Haad, Gonzalo Revilla-González, Cristina Membrives, Juan M DÃaz-Tocados, Julio M MartÃnez-Moreno, Ana I Torralbo, Carmen Herencia, MarÃa Encarnación RodrÃguez-Ortiz, Rodrigo López-Baltanás, Williams G Richards, Arnold Felsenfeld, Yolanda Almadén, Alejandro Martin-Malo, Juan Ureña, Rafael SantamarÃa, Sagrario Soriano, Mariano RodrÃguez, Juan R Muñoz-Castañeda
doi : 10.1093/ndt/gfac220
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 322–343
In chronic kidney disease (CKD) patients, increased levels of fibroblast growth factor 23 (FGF23) are associated with cardiovascular mortality.
Effect of lanthanum carbonate on serum calciprotein particles in patients with stage 3–4 CKD—results from a placebo-controlled randomized trial
Mark K Tiong, Edward R Smith, Elaine M Pascoe, Grahame J Elder, Nicole M Lioufas, Eugenia Pedagogos, Carmel M Hawley, Andrea Valks, Stephen G Holt, Tim D Hewitson, Nigel D Toussaint
doi : 10.1093/ndt/gfac043
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 344–351,
Calciprotein particles (CPP) are colloidal aggregates of calcium phosphate and the mineral-binding protein fetuin-A, and are potential mediators of cardiovascular disease in chronic kidney disease (CKD).
Development and validation of a deep neural network–based model to predict acute kidney injury following intravenous administration of iodinated contrast media in hospitalized patients with chronic kidney disease: a multicohort analysis
Ping Yan, Shao-Bin Duan, Xiao-Qin Luo, Ning-Ya Zhang, Ying-Hao Deng
doi : 10.1093/ndt/gfac049
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 352–361
Stratification of chronic kidney disease (CKD) patients [estimated glomerular filtration rate (eGFR) <60Â mL/min/1.73 m2] at risk for post-contrast acute kidney injury (PC-AKI) following intravenous administration of iodinated contrast media (ICM) is important for clinical decision-making and clinical trial enrollment.
Proposal for individualized dosing of eculizumab in atypical haemolytic uraemic syndrome: patient friendly and cost-effective
Mendy ter Avest, Romy N Bouwmeester, Caroline Duineveld, Kioa L Wijnsma, Elena B Volokhina, Lambertus P W J van den Heuvel, David M Burger, Jack F M Wetzels, Nicole C A J van de Kar, Rob ter Heine, CUREiHUS study group
doi : 10.1093/ndt/gfac056
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 362–371
Eculizumab is a lifesaving yet expensive drug for atypical haemolytic uraemic syndrome (aHUS). Current guidelines advise a fixed-dosing schedule, which can be suboptimal and inflexible in the individual patient.
Kidney outcomes with finerenone: an analysis from the FIGARO-DKD study
Luis M Ruilope, Bertram Pitt, Stefan D Anker, Peter Rossing, Csaba P Kovesdy, Roberto Pecoits-Filho, Pablo Pergola, Amer Joseph, Andrea Lage, Nicole Mentenich, Markus F Scheerer, George L Bakris
doi : 10.1093/ndt/gfac157
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 372–383
In FIGARO-DKD, finerenone reduced the risk of cardiovascular events in patients with type 2 diabetes (T2D) and stage 1–4 chronic kidney disease (CKD).
Biopsy-proven CKD etiology and outcomes: the Chronic Kidney Disease Japan Cohort (CKD-JAC) study
Takayuki Hamano, Takahiro Imaizumi, Takeshi Hasegawa, Naohiko Fujii, Hirotaka Komaba, Masahiko Ando, Masaomi Nangaku, Kosaku Nitta, Hideki Hirakata, Yoshitaka Isaka, Takashi Wada, Shoichi Maruyama, Masafumi Fukagawa
doi : 10.1093/ndt/gfac134
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 384–395,
The Kidney Disease: Improving Global Outcomes guidelines advocate the cause–glomerular filtration rate (GFR)–albuminuria (CGA) classification for predicting outcomes. However, there is a dearth of data supporting the use of the cause of chronic kidney disease.
EXT1 and NCAM1-associated membranous lupus nephritis in a cohort of patients undergoing repeat kidney biopsies
Paul P Miller, Tiffany Caza, Christopher P Larsen, Vivek Charu
doi : 10.1093/ndt/gfac058
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 396–404
Exostosin 1/2 (EXT1/2) and neural cell adhesion molecule 1 (NCAM1) associated membranous lupus nephritis (MLN) may represent distinct disease phenotypes with prognostic significance.
Survival, symptoms and hospitalization of older patients with advanced chronic kidney disease managed without dialysis
Angela Chou, Chenlei Li, Sanjay Farshid, Anna Hoffman, Mark Brown
doi : 10.1093/ndt/gfac154
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 405–413
Shared decision-making (SDM) is important when considering whether an older patient with advanced chronic kidney disease (CKD) should be managed with dialysis or conservative kidney management (CKM).
Eculizumab for paediatric patients with atypical haemolytic uraemic syndrome: full dataset analysis of post-marketing surveillance in Japan
Shuichi Ito, Hiroshi Hataya, Akira Ashida, Riku Hamada, Tomoaki Ishikawa, Yumiko Ishikawa, Akihiko Shimono, Takao Konomoto, Tomoki Miyazawa, Masao Ogura, Kazuki Tanaka, Shoji Kagami
doi : 10.1093/ndt/gfac150
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 414–424
Eculizumab was approved for atypical haemolytic uraemic syndrome (aHUS) in Japan in 2013.
Bone density, microarchitecture and estimated strength in stone formers: a cross-sectional HR-pQCT study
Priscila Ligeiro Gonçalves Esper, Fernanda Guedes Rodrigues, Thalita Lima Melo, Milene Subtil Ormanji, Carlos M Campos, Jackeline Couto Alvarenga, Valeria de Falco Caparbo, Aluizio Barbosa Carvalho, Rosa Maria Rodrigues Pereira, Ita Pfeferman Heilberg
doi : 10.1093/ndt/gfac128
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 425–434
Low areal bone mineral density (BMD), increased fracture risk and altered bone remodeling have been described among stone formers (SFs), but the magnitude of these findings differs by age, sex, menopausal status and urinary calcium (uCa).
Impact of incremental initiation of haemodialysis on mortality: a systematic review and meta-analysis
Emma Caton, Shivani Sharma, Enric Vilar, Kenneth Farrington
doi : 10.1093/ndt/gfac274
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 435–446
Incremental haemodialysis initiation entails lower sessional duration and/or frequency than the standard 4 h thrice-weekly approach. Dialysis dose is increased as residual kidney function (RKF) declines. This systematic review evaluates its safety, efficacy and cost-effectiveness.
A real world comparison of HepB (Engerix-B®) and HepB-CpG (Heplisav-B®) vaccine seroprotection in patients receiving maintenance dialysis
Harold J Manley, Gideon Aweh, Jill Frament, Vladimir Ladik, Eduardo K Lacson, Jr
doi : 10.1093/ndt/gfac039
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 447–454
Vaccination against hepatitis B virus (HBV) is recommended for dialysis patients.
Comparison of the association between six different frailty scales and clinical events in patients on hemodialysis
Keigo Imamura, Shohei Yamamoto, Yuta Suzuki, Shun Yoshikoshi, Manae Harada, Shiwori Osada, Kentaro Kamiya, Ryota Matsuzawa, Atsuhiko Matsunaga
doi : 10.1093/ndt/gfac047
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 455–462
Frailty is associated with adverse outcomes in patients undergoing hemodialysis (HD). However, no study has used various frailty assessments in patients on HD to examine their association with clinical events. In this study, we investigated the association between clinical events and six frailty scales.
Impact of previous REnal TRansplantation on the mid-term renal Outcome after CARdiac surgery: the RETROCAR trial
Antoine Beurton, Antoine Fajardie, Sebastien Rubin, Pierre Belnou, Clement Aguerreche, Mathieu Pernot, Stefano Mion, Julien Imbault, Alexandre Ouattara
doi : 10.1093/ndt/gfac269
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 463–471
Acute kidney injury (AKI) is one of the most common complications after cardiac surgery with cardiopulmonary bypass (CPB). Renal transplant recipients (RTRs) have a higher risk of cardiac surgery–associated AKI (CSA-AKI).
Retrospective analysis of the impact of severe obesity on kidney transplant outcomes
Demetra Tsapepas, Vanessa Sandra, Leigh Ann Dale, Yelena Drexler, Kristen L King, Miko Yu, Katherine Toma, Jennifer Van Bever, Navin Sanichar, S Ali Husain, Sumit Mohan
doi : 10.1093/ndt/gfac169
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 472–480
The prevalence of obesity among kidney transplant recipients is rising. We sought to determine the association between recipient body mass index (BMI) and post-transplant complications.
Belatacept rescue conversion in kidney transplant recipients with vascular lesions (Banff cv score >2):  a retrospective cohort study
Dominique Bertrand, Marie Matignon, Antoine Morel, Lebourg Ludivine, Mathilde Lemoine, Mélanie Hanoy, Frank Le Roy, Dorian Nezam, Mouad Hamzaoui, Tristan de Nattes, Anissa Moktefi, Arnaud François, Charlotte Laurent, Isabelle Etienne, Dominique Guerrot
doi : 10.1093/ndt/gfac178
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 481–490
Immunosuppression in kidney transplant recipients with decreased graft function and histological vascular changes can be particularly challenging. The impact of a late rescue conversion to belatacept on kidney graft survival in this context has never been studied.
Long-term cognitive impairments in kidney transplant recipients: impact on participation and quality of life
Aaltje L Ziengs, Anne M Buunk, Lisanne van Sonderen, Michele F Eisenga, Antonio W Gomes Neto, Coby Annema, Thialda Vlagsma, Gerjan J Navis, Stefan P Berger, Stephan J L Bakker, Jacoba M Spikman
doi : 10.1093/ndt/gfac035
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 491–498
Cognitive impairment is often present shortly after transplantation in kidney transplant recipients (KTR). To date, it is unknown whether these impairments persist in the
De novo major cardiovascular events in kidney transplant recipients: a comparative matched cohort study
Ji Eun Kim, Jina Park, Sehoon Park, Mi-yeon Yu, Seon Ha Baek, Sang Hyun Park, Kyungdo Han, Yong Chul Kim, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo, Yon Su Kim, Hajeong Lee
doi : 10.1093/ndt/gfac144
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 499–506,
Although cardiovascular disease is known to be one of the leading causes of death after kidney transplantation (KT), evidence on the risk difference of de novo major adverse cardiovascular events (MACEs) in kidney transplant recipients (KTRs) compared with that in dialysis patients or the general population (GP) remains rare.
Risk of end-stage kidney disease in kidney transplant recipients versus patients with native chronic kidney disease: multicentre unmatched and propensity-score matched analyses
Luca De Nicola, Raffaele Serra, Michele Provenzano, Roberto Minutolo, Ashour Michael, Nicola Ielapi, Stefano Federico, Rosa Carrano, Vincenzo Bellizzi, Carlo Garofalo, Carmela Iodice, Silvio Borrelli, Giuseppe Grandaliano, Giovanni Stallone, Loreto Gesualdo, Paolo Chiodini, Michele Andreucci
doi : 10.1093/ndt/gfac131
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 507–516
In kidney transplant recipients (KTR), the end-stage kidney disease (ESKD) risk dependent on the risk factors acting in native chronic kidney disease (CKD) remains undefined.
Isolated kidney transplantation under lumasiran therapy in primary hyperoxaluria type 1: a report of five cases
Anne-Laure Sellier-Leclerc, Elisabeth Metry, Stéphanie Clave, Peggy Perrin, Cécile Acquaviva-Bourdain, Charlène Levi, Meindert Crop, Sophie Caillard, Bruno Moulin, Jaap Groothoff, Justine Bacchetta
doi : 10.1093/ndt/gfac295
Nephrology Dialysis Transplantation, Volume 38, Issue 2, February 2023, Pages 517–521
