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Circulation Global Rounds: France.
Danchin, Nicolas MD, PhD; Bouleti, Claire MD, PhD
doi : 10.1161/CIRCULATIONAHA.122.059479
Volume 147(5) pgs. 361-449,e70-e72 January 31, 2023
Myocardial Involvement After Hospitalization for COVID-19 Complicated by Troponin Elevation: A Prospective, Multicenter, Observational Study.
Artico, Jessica MD ,*; Shiwani, Hunain BMBS ,*; Moon, James C. MD ,*; Gorecka, Miroslawa MB; McCann, Gerry P. MD; Roditi, Giles MD; Morrow, Andrew PhD; Mangion, Kenneth PhD; Lukaschuk, Elena MSc; Shanmuganathan, Mayooran MBBS; Miller, Christopher A. PhD; Chiribiri, Amedeo PhD; Prasad, Sanjay K. MD; Adam, Robert D. MBBS; Singh, Trisha MBBS; Bucciarelli-Ducci, Chiara PhD; Dawson, Dana PhD; Knight, Daniel MD; Fontana, Marianna PhD; Manisty, Charlotte PhD; Treibel, Thomas A. PhD; Levelt, Eylem PhD; Arnold, Ranjit MD; Macfarlane, Peter W. DSc; Young, Robin PhD; McConnachie, Alex PhD; Neubauer, Stefan MD; Piechnik, Stefan K. PhD; Davies, Rhodri H. PhD; Ferreira, Vanessa M. PhD; Dweck, Marc R. PhD; Berry, Colin PhD; OxAMI (Oxford Acute Myocardial Infarction Study) Investigators; COVID-HEART Investigators; Greenwood, John P. PhD
doi : 10.1161/CIRCULATIONAHA.122.060632
Acute myocardial injury in hospitalized patients with coronavirus disease 2019 (COVID-19) has a poor prognosis. Its associations and pathogenesis are unclear. Our aim was to assess the presence, nature, and extent of myocardial damage in hospitalized patients with troponin elevation.
Acute Myocardial Injury in the COVID-HEART Study: Emphasizing Scars While Reassuring Scares.
Stuber, Matthias PhD; Baggish, Aaron L. MD
Challenging the Hemodynamic Hypothesis in Heart Failure With Preserved Ejection Fraction: Is Exercise Capacity Limited by Elevated Pulmonary Capillary Wedge Pressure?.
Sarma, Satyam MD ,,*; MacNamara, James P. MD, MSCS ,,*; Balmain, Bryce N. PhD; Hearon, Christopher M. Jr PhD; Wakeham, Denis J. PhD; Tomlinson, Andrew R. MD; Hynan, Linda S. PhD; Babb, Tony G. PhD; Levine, Benjamin D. MD
Macrophage-Derived 25-Hydroxycholesterol Promotes Vascular Inflammation, Atherogenesis, and Lesion Remodeling.
Canfran-Duque, Alberto PhD; Rotllan, Noemi PhD; Zhang, Xinbo PhD; Andres-Blasco, Irene PhD; Thompson, Bonne M. PhD; Sun, Jonathan BS; Price, Nathan L. PhD; Fernandez-Fuertes, Marta BS; Fowler, Joseph W. PhD; Gomez-Coronado, Diego PhD; Sessa, William C. PhD; Giannarelli, Chiara MD, PhD; Schneider, Robert J. PhD; Tellides, George MD, PhD; McDonald, Jeffrey G. PhD; Fernandez-Hernando, Carlos PhD; Suarez, Yajaira PhD
doi : 10.1161/CIRCULATIONAHA.122.059062
Cross-talk between sterol metabolism and inflammatory pathways has been demonstrated to significantly affect the development of atherosclerosis. Cholesterol biosynthetic intermediates and derivatives are increasingly recognized as key immune regulators of macrophages in response to innate immune activation and lipid overloading.
Distinct Transcriptomic and Proteomic Profile Specifies Patients Who Have Heart Failure With Potential of Myocardial Recovery on Mechanical Unloading and Circulatory Support.
Drakos, Stavros G. MD, PhD; Badolia, Rachit PhD; Makaju, Aman MS; Kyriakopoulos, Christos P. MD; Wever-Pinzon, Omar MD; Tracy, Christopher M. PhD; Bakhtina, Anna BS; Bia, Ryan BS; Parnell, Timothy PhD; Taleb, Iosif MD; Ramadurai, Dinesh K.A. BS; Navankasattusas, Sutip PhD; Dranow, Elizabeth PhD; Hanff, Thomas C. MD; Tseliou, Eleni MD, PhD; Shankar, Thirupura S. BS; Visker, Joseph PhD; Hamouche, Rana MD; Stauder, Elizabeth L. BS; Caine, William T. MD; Alharethi, Rami MD; Selzman, Craig H. MD; Franklin, Sarah PhD
doi : 10.1161/CIRCULATIONAHA.121.056600
Extensive evidence from single-center studies indicates that a subset of patients with chronic advanced heart failure (HF) undergoing left ventricular assist device (LVAD) support show significantly improved heart function and reverse structural remodeling (ie, termed "responders").
Cardiovascular Complications of Down Syndrome: Scoping Review and Expert Consensus.
Dimopoulos, Konstantinos MD, PhD, MSc ,,*,+; Constantine, Andrew MBBS, MA ,,*,+; Clift, Paul MBBS, MD, BA ,*; Condliffe, Robin MD ,*; Moledina, Shahin MBChB ,,*; Jansen, Katrijn MD ,,*; Inuzuka, Ryo MD, PhD; Veldtman, Gruschen R. MBChB; Cua, Clifford L. MD; Tay, Edgar Lik Wui MBBS, MMed; Opotowsky, Alexander R. MD, MPH, MMSc; Giannakoulas, George MD, PhD; Alonso-Gonzalez, Rafael MD, MSc; Cordina, Rachael MBBS, PhD; Capone, George MD; Namuyonga, Judith MBChB, MMed; Scott, Charmaine H. OD, BSc, MBBS, DCH, DM(Paeds); D'Alto, Michele MD, PhD; Gamero, Francisco J. MD; Chicoine, Brian MD; Gu, Hong MD, PhD; Limsuwan, Alisa MD; Majekodunmi, Tosin BSc, PhD, MBBS; Budts, Werner MD, PhD; Coghlan, Gerry MB BCh, BAO, MD; Broberg, Craig S. MD; for Down Syndrome International (DSi); Dimopoulos, Konstantinos MD, PhD, MSc; Constantine, Andrew MBBS, MA; Clift, Paul MBBS, MD, BA; Condliffe, Robin MD; Moledina, Shahin MBChB; Jansen, Katrijn MD
doi : 10.1161/CIRCULATIONAHA.122.059706
AB Cardiovascular disease is a leading cause of morbidity and mortality in individuals with Down syndrome. Congenital heart disease is the most common cardiovascular condition in this group, present in up to 50% of people with Down syndrome and contributing to poor outcomes.
Syncope After Transcatheter Aortic Valve Implantation: Pace or Not?.
Dar, Javaid Ahmad MBBS, MD, DM; Manickavasagam, Anand MBBS, MD, DM; Jacob, John Roshan MBBS, MD, DM, CEPS, CCDS
Impact of Patient Selection on Performance of an Early Rule-Out Pathway for Myocardial Infarction: From Research to the Real World.
Bularga, Anda MD; Ken Lee, Kuan MD; Shah, Anoop S.V. MD; Anand, Atul MD; Chapman, Andrew R. MD; Tuck, Chris BSc; Newby, David E. MD; Jenks, Sarah MBChB; Mills, Nicholas L. MD; Kimenai, Dorien M. PhD
Letter by Zhou et al Regarding Article, "Deep Lipidomics in Human Plasma: Cardiometabolic Disease Risk and Effect of Dietary Fat Modulation".
Zhou, Hong MD ,*; Ren, Chuanli MD ,*; Yang, Zhanjun PhD ,*
Response by Eichelmann and Schulze to Letter Regarding Article, "Deep Lipidomics in Human Plasma: Cardiometabolic Disease Risk and Effect of Dietary Fat Modulation".
Eichelmann, Fabian PhD; Schulze, Matthias B. DrPH
