Alain Lescoat
doi : 10.1177/23971983221129211
Volume 8 Issue 1, February 2023
The early diagnosis of systemic sclerosis has been a major challenge for the scleroderma community in the past 50 years. The recent publication of the predictive value of the VEDOSS (Very Early Diagnosis of Systemic Sclerosis) criteria in the Lancet Rheumatology in December 2021 has provided an unprecedented insight in the early stages of the disease.
Kristina EN Clark
doi : 10.1177/23971983221126850
Both antineutrophil cytoplasmic antibody-associated vasculitis and systemic sclerosis are rare autoimmune diseases. Both have the potential for significant multi-organ involvement, and both carry high morbidity and mortality. Disease-specific autoantibodies in these conditions allow for risk stratification for organ-based complications, and for personalised therapeutic strategies.
Erin Chew1 , April Barnado1 , Talat Alp Ikizler2,3 , Roy Zent2,3 and Tracy Frech1,
doi : 10.1177/23971983221122673
Patients with systemic sclerosis and systemic lupus erythematosus serologies present a unique challenge to the clinician when hypertension is detected in the outpatient setting. Treatment choices for non-renal crisis hypertension are different for systemic sclerosis versus systemic lupus erythematosus.
Ram Raj Singh1,2,3,4 , Devanshu R Singh1,5 and Eric Y Yen
doi : 10.1177/23971983221140538
Male sex and black race incur poor prognosis in systemic sclerosis (SSc). There is no nationwide population-based assessment of premature SSc death burden by sex and race.
Siobhan Deshauer1 , Mats Junek1 , Murray Baron2, Karen A Beattie1 and Margaret J Larché1
doi : 10.1177/23971983221101311
To explore the trajectory of scleroderma disease activity in women who experienced a pregnancy after systemic sclerosis diagnosis compared to nulliparous women.
David Ozeri1 , Shani Peretz1 , Amit Oppenheim2 , Abdallah Watad3 , Merav Lidar 4 and Yolanda Braun-Moscovici
doi : 10.1177/23971983221138712
The aim of this study was to test the reliability of the University of California, Los Angeles Scleroderma Clinical Trial Consortium Gastrointestinal Tract (UCLA SCTC GIT) 2.0 questionnaire in Hebrew.
Lily A Romero-Karam1 , Kevin A Honan2, Salman A Arain3 and Maureen D. Mayes1
doi : 10.1177/23971983221116669
The objective of this study is to explore the role of adjunctive percutaneous revascularization of the hand in the management of patients with systemic sclerosis–associated refractory digital ischemia.
Theerajet Guayboon1 and Chayawee Muangchan
doi : 10.1177/23971983221118720
To investigate the prevalence of and independent predictors for digital ischemic complications in patients with systemic sclerosis.
Malin Mattsson1,2 , Roger Hesselstrand3,4 , Karin Gunnarsson5 , Elisabet Dyrsmeds6 , Monica Holmner7 , Annica Nordin5 and Carina Boström1,8
doi : 10.1177/23971983221107858
Systemic sclerosis (SSc) can lead to visible changes in appearance which could generate concerns among patients. Thus, valid questionnaires that capture these concerns are valuable to identify and communicate appearance concerns.
Sarah JH Khidir1 , Maaike Boonstra1 , Sytske Anne Bergstra1 , Gerry WM Boerrigter2 , Elles M Voogt-van der Harst2 , Maarten K Ninaber3 , Nina Ajmone Marsan4 , Tom WJ Huizinga1 , Annette HM van der Helm-van Mil1,5 and Jeska K de Vries-Bouwstra
doi : 10.1177/23971983221138177
Decreased maximal mouth opening is a common and disabling manifestation in systemic sclerosis patients. We aimed to study the course of maximal mouth opening, determinants of smaller maximal mouth opening over time and the burden of smaller maximal mouth opening on mouth handicap.
Akash Babulal Vadher1 , Anindita Sinha2 , Shayeri Roy Choudhury2 , Mahesh Prakash2 , Muniraju Maralakunte2 , Tanveer Rehman3 , Shefali Sharma4 and Yashwant Kumar5
doi : 10.1177/23971983221140673
Prevalence of synovitis, tenosynovitis, erosions, acro-osteolysis and bone marrow edema in systemic sclerosis is not extensively reported. We aimed to estimate the prevalence of changes in individual joints of hands in systemic sclerosis patients.
MarÃlia M Sampaio-Barros1 , Adriana B Bortoluzzo2 , Henrique Carriço da Silva1 , Ana Paula Luppino-Assad1 , Rosa Maria R Pereira1* and Percival D Sampaio-Barros
doi : 10.1177/23971983221141271
This case–control study analyzed risk factors for symptomatic fractures in a group of 52 patients with systemic sclerosis compared with a group of 104 patients without fractures, matched for sex and age, who were attended at a single systemic sclerosis outpatient clinic from 2010 to 2020.
Fadi Hassan1,2 , Firas Sabbah2,3 and Mohammad E Naffaa
doi : 10.1177/23971983221101296
Scleroderma renal crisis is a rare but serious complication of systemic sclerosis. It is usually associated with marked hypertension and carries significant risk for morbidity and mortality. Its occurrence prior to the development of skin sclerosis is exceedingly rare.
Clothilde Gros1 , Olivier Fogel1 , Idris Boudhabhay2 , Charlotte Debiais2 , Jean-Paul Duong Van Huyen3 , Aurélie Hummel2 , Yannick Allanore1 and Jérôme Avouac1
doi : 10.1177/23971983221099847
We report the case of a patient followed for a mixed connective tissue disease with signs of systemic sclerosis and systemic lupus, who presented an acute renal failure with severe neurological symptoms (confusion, obnubilation) and hypertension.
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