Birgitte Vrou Offersen a,b,c,⇑, Marianne C. Aznar d , Carol Bacchus e , Rob P. Coppes f , Eric Deutsch g , Dieter Georg h , Karin Haustermans i , Peter Hoskin j , Mechthild Krause k,l , Eric F. Lartigau m , Anne W.M. Lee n , Steffen Löck l , David I. Thwaites o,p , Albert J. van der Kogel q , Uulke van der Heide r , Vincenzo Valentini s , Jens Overgaard a , Michael Baumann
doi : 10.1016/j.radonc.2022.109446
Volume 179, February 2023, 109446
Susann Wolfram a , Jamie Seul Ki Takayesu b , Lori Jo Pierce b , Reshma Jagsi b , David Benjamin Lipps
doi : 10.1016/j.radonc.2022.109450
Volume 179, February 2023, 109450
Radiotherapy (RT) is a common and often essential treatment for breast cancer, but has been associated with pectoralis major (PM) muscle fibrosis and atrophy. In an initial prospective evaluation, we assessed muscle stiffness and muscle thickness of the sternocostal and clavicular regions of the PM with ultrasound shear wave elastography and B-mode imaging.
doi : 10.1016/j.radonc.2022.109455
Volume 179, February 2023, 109455
Total neoadjuvant therapy (TNT) can enhance local tumor regression, but its survival benefits compared to intensified chemoradiotherapy (CRT) followed by adjuvant chemotherapy (CT) remain unclear.
Guang-Li Zhu a,b,1 , Xiao-Min Zhang a,c,1 , Kai-Bin Yang a,1 , Ling-Long Tang a,⇑, Jun Ma
doi : 10.1016/j.radonc.2022.109447
Volume 179, February 2023, 109447
The current cervical lymph nodes classification system is not perfectly reasonable for radiotherapy of nasopharyngeal carcinoma (NPC). This study aimed to determine the metastatic patterns of level II-V lymph nodes in NPC by using vertebrae as anatomical landmarks.
Yang Liu a , Ye Zhang a , Jingbo Wang a , Xiaodong Huang a , Kai Wang a , Yuan Qu a , Xuesong Chen a , Qingfeng Liu a , Jianghu Zhang a , Jingwei Luo a , Yexiong Li a , Runye Wu a,⇑, Junlin Yi
doi : 10.1016/j.radonc.2022.109443
Volume 179, February 2023, 109443
To investigate the caudal distribution pattern of metastatic neck lymph nodes (LNs) in nasopharyngeal carcinoma (NPC) and the prognostic significance of nodal spread distances (SDs).
Xiaotao Huang a,b,1 , Mingzan Zhuang c,1 , Shuai Yang a,1 , Ying Wang d,1 , Qiaodan Liu a , Xiwei Xu a , Mei Xiao a , Yingpeng Peng a,b , Ping Jiang d , Wenhua Xu d , Shuanshuan Guo a , Rong Wang a,b , Wei Wei a,b , Guihua Zhong a,b , Yuling Zhou a,b , Shunli Peng a,b , Xuanzi Li a , Jianqi Cui a , Siyang Wang a , Yaqin Zhang e , Zhigang Liu a,b,f,
doi : 10.1016/j.radonc.2022.109440
Volume 179, February 2023, 109440
Dynamic positron emission tomography/computed tomography (PET/CT) served the potential role of characterizing malignant foci. The main objective of this prospective study was to explore the advantage of dynamic PET/CT imaging in characterizing nasopharyngeal carcinoma (NPC).
Jing-rong Mao a,b,1 , Kai-qi Lan a,c,1 , Sai-lan Liu a,c,1 , Chen Liu b , Si-yi Xie a,c , Su-chen Li a,c , Wen-feng Ye b,2 , Xue-song Sun a,c,2 , Hai-qiang Mai
doi : 10.1016/j.radonc.2022.109445
Volume 179, February 2023, 109445
We sought to determine the prognostic value of a pre-treatment peripheral blood signature and the peripheral blood signature-based nomogram for patients with non-metastatic nasopharyngeal carcinoma (NPC).
Artuur M. Leeuwenberg a,⇑, Johannes B. Reitsma a , Lisa G.L.J. Van den Bosch b , Jeroen Hoogland a , Arjen van der Schaaf b , Frank J.P. Hoebers c , Oda B. Wijers d , Johannes A. Langendijk b , Karel G.M. Moons a , Ewoud Schuit
doi : 10.1016/j.radonc.2022.109449
Volume 179, February 2023, 109449
Normal-tissue complication probability (NTCP) models predict complication risk in patients receiving radiotherapy, considering radiation dose to healthy tissues, and are used to select patients for proton therapy, based on their expected reduction in risk after proton therapy versus photon radiotherapy (ΔNTCP).
Victoria Sarah Brennan a,⇑, Sarah Burleson b , Caroline Kostrzewa c,1 , Paola Godoy Scripes b , Ergys Subashi b , Zhigang Zhang c , Neelam Tyagi b , Michael J. Zelefsky
doi : 10.1016/j.radonc.2022.109441
Volume 179, February 2023, 109441
Using an magnetic resonance linear accelerator (MR-Linac) may improve the precision of visible tumor boosting with ultra-hypofractionation by accounting for daily positional changes in the target and organs at risk (OAR).
Ke Tang a,1,⇑, Nan Zhang b,1 , Xiaodong Yuan c,1 , Zenghui Qian d , Yang Li e , Xu Feng
doi : 10.1016/j.radonc.2022.109451
Volume 179, February 2023, 109451
Gamma knife surgery (GKS) for brain metastases (BMs) adjacent to the pyramidal tract (PT) is still a challenge to conduct. PT visualization and biologically effective dose (BED) calculation on a voxel-by-voxel basis may provide data to establish clinically safe values.
Rachelle R. Swart a,⇑, Rianne Fijten a , Liesbeth J. Boersma a , Petros Kalendralis a , Myra D. Behrendt c , Martijn Ketelaars b , Cheryl Roumen a , Maria J.G. Jacobs
doi : 10.1016/j.radonc.2022.109459
Volume 179, February 2023, 109459
The aim of this study was to externally validate a model that predicts timely innovation implementation, which can support radiotherapy professionals to be more successful in innovation implementation.
Norifumi Mizuno a,⇑, Hiroyuki Okamoto b , Toshiyuki Minemura c , Shinji Kawamura d , Naoki Tohyama e , Masahiko Kurooka f , Ryu Kawamorita g , Masaru Nakamura h , Yoshinori Ito i , Yoshiyuki Shioyama j , Hidefumi Aoyama k , Hiroshi Igaki
doi : 10.1016/j.radonc.2022.109452
Volume 179, February 2023, 109452
Quality indicators (QIs) for radiotherapy have been proposed by several groups, but no study has been conducted to correlate the implementation of indicators specific to patient safety over the course of the clinical process with an institution’s background
Enrica Seravalli a,⇑, Michelle Sierts a , Eric Brand a , Matteo Maspero a , Szabolcs David a , Mariellen E.P. Philippens a , Eduward H.J. Voormolen b , Joost J.C. Verhoeff
doi : 10.1016/j.radonc.2022.109456
Volume 179, February 2023, 109456
Post-operative radiosurgery (SRS) of brain metastases patients is typically planned on a post-recovery MRI, 2–4 weeks after resection. However, the intracranial metastasis may (re-)grow in this period. Planning SRS directly on the post-operative MRI enables shortening this time interval, anticipating the start of adjuvant systemic therapy, and so decreasing the chance of extracranial progression. The MRI-Linac (MRL) allows the simultaneous execution of the post-operative MRI and SRS treatment. The aim of this work was investigating the dosimetric feasibility of MRL-based post-operative SRS.
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