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Update on Femtosecond Laser-Enabled Keratoplasty.
Tran, Tu M. MD, MSc *; Farid, Marjan MD +
doi : 10.1097/ICO.0000000000003146
Volume 42(4) pgs. 395-528 April 2023
Single-Staged Surgical Correction of Eyelid Sequelae Along With Lid Margin Mucous Membrane Grafting in Stevens-Johnson Syndrome and Other Cicatricial Ocular Surface Diseases.
Shree, Neha MS *; Das, Sima MS *; Arya, Deepanjali MS *; Srivastava, Ankit DO, DNB *; Singh, Aastha MD +; Sangwan, Virender MS +
doi : 10.1097/ICO.0000000000003021
The purpose of this study was to study the outcome of single-staged entropion surgery along with lid margin mucous membrane grafting for cicatrizing ocular surface disease.
Occurrence of Herpes Viruses in Morphologically Normal Corneas.
Nche, Eleanor N. MD *; Katzir, Ayala MD *; Solomon, Avraham MD, PhD *; Wolf, Dana MD +; Panet, Amos PhD ++; Lavy, Itay MD *
doi : 10.1097/ICO.0000000000002977
The purpose of this study was to detect the occurrence of herpes simplex virus (HSV) types 1 and 2 and varicella zoster virus (VZV) DNA in transplanted corneas using polymerase chain reaction (PCR) and to determine the relationship between latent HSV and VZV and herpetic eye disease in recipients.
Accuracy of a New Noninvasive Automatic Ocular Surface Analyzer for the Diagnosis of Dry Eye Disease-Two-Gate Design Using Healthy Controls.
Rinert, Janosch MMed *,+; Branger, Giacomo MD *; Bachmann, Lucas M. MD, PhD +,++; Pfaeffli, Oliver MD *; Iselin, Katja MD *; Kaufmann, Claude MD *,+; Thiel, Michael A. MD, PhD *,+; Baenninger, Philipp B. MD *,+
doi : 10.1097/ICO.0000000000003052
The purpose of this study was to assess the diagnostic performance of measurements from a new noninvasive, automated ocular surface analyzer (IDRA) in the diagnosis of dry eye disease (DED).
Safety and Efficacy of Repeated Corneal Collagen Crosslinking in Progressive Keratoconus.
Vorobichik Berar, Ofri MD, MHA; Rotenberg, Michael MD; Berger, Yoav MD; Matani, Adham MD; Avni-Zauberman, Noa MD, MHA; Barequet, Irina S. MD, MHA
doi : 10.1097/ICO.0000000000003165
Keratoconus is a progressive visually impairing disorder. Despite the beneficial effects of epithelial off-crosslinking (CXL) on the stabilization of keratoconus, progression may still occur.
Clinical and Optical Coherence Tomography Comparison Between Ocular Surface Squamous Neoplasia and Squamous Metaplasia.
Stevens, Shanlee M. MD *; Reyes-Capo, Daniela P. MD *; Patel, Umangi MD *; Choudhary, Anjalee MD *; Khzam, Rayan Abou MD *; Tang, Vincent BS *; Galor, Anat MD, MSPH *,+; Karp, Carol L. MD *; Dubovy, Sander MD *
doi : 10.1097/ICO.0000000000003039
The purpose of this study was to compare the clinical characteristics and high-resolution optical coherence tomography (HR-OCT) findings between corneal squamous metaplasia and ocular surface squamous neoplasia (OSSN).
Lotilaner Ophthalmic Solution, 0.25%, for the Treatment of Demodex Blepharitis: Results of a Prospective, Randomized, Vehicle-Controlled, Double-Masked, Pivotal Trial (Saturn-1).
Yeu, Elizabeth MD *; Wirta, David L. MD +; Karpecki, Paul OD ++; Baba, Stephanie N. OD [S]; Holdbrook, Mark BA [S]; Saturn I Study Group
doi : 10.1097/ICO.0000000000003097
The purpose of this study was to evaluate the safety and efficacy of lotilaner ophthalmic solution, 0.25%, compared with vehicle for the treatment of Demodex blepharitis.
Alcohol Abuse Is Associated With Alterations in Corneal Endothelial Cell Morphology.
Karmakar, Ranit BTech *; Nooshabadi, Saeid PhD *; Lohmeier, John CEBT +; Terrin, Staci CEBT +; Eghrari, Allen O. MD, MPH ++
doi : 10.1097/ICO.0000000000003067
Alcohol consumption is highly prevalent throughout the world. We sought to detect, in a large sample of cornea donors, whether alcohol abuse is associated with changes in corneal endothelial morphology after accounting for other comorbidities including tobacco use.
Descemet Stripping Endothelial Keratoplasty: Fifteen-Year Outcomes.
Price, Marianne O. PhD *; Price, Francis W. Jr MD +
doi : 10.1097/ICO.0000000000003022
The purpose of this study was to evaluate 15-year outcomes of Descemet stripping endothelial keratoplasty (DSEK). Methods: We retrospectively reviewed an initial, consecutive series of 350 DSEK cases in 290 patients (mean age 69 years), performed between December 2003 and December 2005 for Fuchs dystrophy (86%), pseudophakic/aphakic bullous keratopathy (10%), or failed penetrating keratoplasty (4%).
Mobile-CellNet: Automatic Segmentation of Corneal Endothelium Using an Efficient Hybrid Deep Learning Model.
Karmakar, Ranit BS *; Nooshabadi, Saeid V. PhD *; Eghrari, Allen O. MD, MPH +
doi : 10.1097/ICO.0000000000003186
The corneal endothelium, the innermost layer of the human cornea, exhibits a morphology of predominantly hexagonal cells. These endothelial cells are believed to have limited regeneration capacity, and their density decreases over time.
Novel DCN Mutation in Armenian Family With Congenital Stromal Corneal Dystrophy.
Williams, Dominic BS *; Chung, Doug D. PhD *; Hovakimyan, Anna MD, PhD +; Davtyan, Araks MD +; Glasgow, Ben J. MD *; Aldave, Anthony J. MD *
doi : 10.1097/ICO.0000000000003167
Congenital stromal corneal dystrophy (CSCD) is a rare congenital, dominantly inherited disorder characterized by diffuse stromal opacification associated with mutations in the decorin gene (DCN). As only 5 families with genetically confirmed CSCD have been reported, the identification of a novel pedigree provides the opportunity to better characterize the phenotype and genetic basis.
Descemet Stripping Only Technique for Corneal Endothelial Damage in Mice.
Nakagawa, Hayate MD, PhD; Alemi, Hamid MD, MPH; Wang, Shudan MD, PhD; Kahale, Francesca MD; Blanco, Tomas PhD; Liu, Catherine MD; Yin, Jia MD, MPH, PhD; Dohlman, Thomas H. MD; Dana, Reza MD, MPH, MSc
Ophthalmic Manifestations of Arterial Tortuosity Syndrome: Case Series of Patient and Carriers.
Alharbi, Saad S. MD *,+; Algorinees, Rakan M. MD *,++; Alshehri, Merai A. MD *,[S]
doi : 10.1097/ICO.0000000000003226
The aim of this study was to report the detailed ophthalmic findings in a young patient with genetically confirmed arterial tortuosity syndrome (ATS) and the findings in 8 family members who were carriers.
Inadvertent Viscoelastic Separation of the Pre-Descemet (Dua) Layer in Deep Anterior Lamellar Keratoplasty With Structural Features Revealed by Polarization Microscopy.
Helm, Craig J. MD *; Glasgow, Ben J. MD +
doi : 10.1097/ICO.0000000000003216
Deep anterior lamellar keratoplasty (DALK) is a corneal transplant technique that removes the host stroma down to either the pre-Descemet (Dua) layer or Descemet membrane.
Combined Temporary Pupilloplasty and DSEK in an Eye With a Hydrophilic Acrylic Intraocular Lens to Prevent Opacification: A Case Report.
Chen, Ariel MD *; Woreta, Fasika A. MD, MPH +; Jun, Albert S. MD, PhD +
doi : 10.1097/ICO.0000000000003206
The aim of this study was to describe a case of temporary pupilloplasty during Descemet stripping endothelial keratoplasty to prevent opacification of a hydrophilic acrylic intraocular lens (IOL).
Classification of Tear Film Lipid Layer En Face Maps Obtained Using Optical Coherence Tomography and Their Correlation With Clinical Parameters.
Stegmann, Hannes *,+; Aranha Dos Santos, Valentin *,+; Schmidl, Doreen ++; Garhofer, Gerhard ++; Fard, Ali [S]; Bagherinia, Homayoun [S]; Schmetterer, Leopold *,+,++,[P],||,**,++,++++; Werkmeister, Rene M. *,+
doi : 10.1097/ICO.0000000000003172
The purpose of this study was to investigate the correlation between the pattern of optical coherence tomography (OCT) en face maps of the tear film lipid layer (TFLL) and lipid layer thickness (LLT), fluorescein breakup time (FBUT), and Schirmer I test values in healthy subjects.
Allogeneic Solid Platelet-Rich Plasma for Persistent Epithelial Neurotrophic Defects: A Protocol and Pilot Study.
Romano, Vito MD, FRCOphth *; Bignotti, Stefano MD *; Forbice, Eliana MD, PhD *; Bianchetti, Andrea MSc +; Almici, Camillo MD +; Semeraro, Francesco MD *
doi : 10.1097/ICO.0000000000003204
Here, we present the procedure to obtain allogeneic solid platelet-rich plasma (PRP) and its use in a pilot study of patients with persistent neurotrophic epithelial defects.
Dupilumab-Induced, Tralokinumab-Induced, and Belantamab Mafodotin-Induced Adverse Ocular Events-Incidence, Etiology, and Management.
Mickevicius, Tomas MD *,+; Pink, Andrew E. BSc (Hons), BMBS, MRCP, PhD ++; Bhogal, Maninder BSc, MBBS, FRCOphth, PhD, FEBOS-CR, Cert LRS *; O'Brart, David MBBS, MD (Res), FRCS, FRCOphth, DO, CertLRS *; Robbie, Scott J. MBBS, BSc, GMP, PGDip, PhD, FRCOphth, CertLRS *
doi : 10.1097/ICO.0000000000003162
AB Emerging monoclonal antibody therapies are assuming greater importance in the management of severe and refractory forms of immunity-driven and oncological disorders. However, some have been found to induce adverse ocular events (AOEs) leading to discontinuation of treatment or additional multidisciplinary management.
Prevalence and Predictors of Knowledge and Attitudes Toward Eye Donation Among the General Population: A Systematic Review.
Chumkasian, Waraporn MN *,+; Fernandez, Ritin PhD *,++; Petsoglou, Constantinos MMED +,[S]; Green, Heidi MPH *,++; Taylor, Catriona BS *; Vlahu-Gjorgievska, Elena PhD [P]; Win, Khin Than PhD [P]
