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2022 American College of Rheumatology Guideline for Vaccinations in Patients With Rheumatic and Musculoskeletal Diseases
Anne R. Bass, Eliza Chakravarty, Elie A. Akl, Clifton O. Bingham, Leonard Calabrese, Laura C. Cappelli, Sindhu R. Johnson, Lisa F. Imundo, Kevin L. Winthrop, Reuben J. Arasaratnam, Lindsey R. Baden, Roberta Berard, S. Louis Bridges Jr., Jonathan T. L. Cheah, Jeffrey R. Curtis, Polly J. Ferguson, Ida Hakkarinen, Karen B. Onel, Grayson Schultz, Vidya Sivaraman, Benjamin J. Smith, Jeffrey A. Sparks, Tiphanie P. Vogel, Eleanor Anderson Williams, Cassandra Calabrese, Joanne S. Cunha, Joann Fontanarosa, Miriah C. Gillispie-Taylor, Elena Gkrouzman, Priyanka Iyer, Kimberly S. Lakin, Alexandra Legge, Mindy S. Lo, Megan M. Lockwood, Rebecca E. Sadun, Namrata Singh, Nancy Sullivan, Herman Tam, Marat Turgunbaev, Amy S. Turner, James Reston … See fewer authors
doi : 10.1002/acr.25045
To provide evidence-based recommendations on the use of vaccinations in children and adults with rheumatic and musculoskeletal diseases (RMDs).
Improving the Effect of Nonsurgical Interventions in People With Osteoarthritis
Joost Dekker
doi : 10.1002/acr.24981
How Do Nonsurgical Interventions Improve Pain and Physical Function in People With Osteoarthritis? A Scoping Review of Mediation Analysis Studies
Yuri Lopes Lima, Hopin Lee, David M. Klyne, Fiona L. Dobson, Rana S. Hinman, Kim L. Bennell, Michelle Hall
doi : 10.1002/acr.24983
Nonsurgical interventions are recommended for osteoarthritis (OA). However, how interventions change pain and physical function is unclear. Therefore, the objectives of this scoping review were to 1) identify what potential mediators of nonsurgical interventions on pain and physical function have been evaluated and 2) summarize the findings according to intervention, joint, and outcome.
Loss of Productivity-Adjusted Life-Years in Working-Age Australians Due to Knee Osteoarthritis: A Life-Table Modeling Approach
Xingzhong Jin, Ilana N. Ackerman, Zanfina Ademi
doi : 10.1002/acr.24886
Productivity-adjusted life-years (PALYs) offers a novel approach for quantifying the productivity burden of chronic conditions at the population level over the working lifespan. This study was undertaken to estimate the productivity burden of knee osteoarthritis (KOA) among working-age Australians, defined as lost PALYs and lost gross domestic product (GDP).
Cost-Effectiveness of Surgical Weight-Loss Interventions for Patients With Knee Osteoarthritis and Class III Obesity
Aleksandra M. Kostic, Valia P. Leifer, Yusi Gong, Malcolm K. Robinson, Jamie E. Collins, Tuhina Neogi, Stephen P. Messier, David J. Hunter, Faith Selzer, Lisa G. Suter, Jeffrey N. Katz, Elena Losina
doi : 10.1002/acr.24967
Class III obesity (body mass index [BMI] ≥40 kg/m2) is associated with worse knee pain and total knee replacement (TKR) outcomes. Because bariatric surgery yields sustainable weight loss for individuals with BMI ≥40 kg/m2, our objective was to establish the value of Roux-en-Y gastric bypass (RYGB) and laparoscopic sleeve gastrectomy (LSG) in conjunction with usual care for knee osteoarthritis (OA) patients with BMI ≥40 kg/m2.
Personalized Risk Model and Leveraging of Magnetic Resonance Imaging–Based Structural Phenotypes and Clinical Factors to Predict Incidence of Radiographic Osteoarthritis
Jinhee J. Lee, Nikan K. Namiri, Bruno Astuto, Thomas M. Link, Sharmila Majumdar, Valentina Pedoia
doi : 10.1002/acr.24877
Our study aimed to investigate the association between time to incidence of radiographic osteoarthritis (OA) and magnetic resonance imaging (MRI)–based structural phenotypes proposed by the Rapid Osteoarthritis MRI Eligibility Score (ROAMES).
Association of Diabetes Mellitus Status and Hyperglycemia With Symptomatic Knee Osteoarthritis
Jiazhen Zheng, Xihao Huang, Jinghan Huang, Bingyao Meng, Furong Li, Huamin Liu, Liren Chen, Rui Zhou, Mengchen Zou, Xianbo Wu
doi : 10.1002/acr.24872
Emerging evidence indicates that hyperglycemia has an adverse impact on the knee joint which, in turn, may increase the risk of knee osteoarthritis (OA), but evidence from the real-life settings of large-scale cohort studies remains unclear. We sought to evaluate the association of glycemic control and the risk of symptomatic knee OA in a community-based cohort of older adults.
Factors Associated With the Initiation and Retention of Patients With Lupus in the Chronic Disease Self-Management Program
Titilola Falasinnu, Gaobin Bao, Teresa J. Brady, S. Sam Lim, Cristina Drenkard
doi : 10.1002/acr.24811
The Chronic Disease Self-Management Program (CDSMP) is designed to enhance patients' self-efficacy and skills to manage their chronic illness. There is compelling evidence for the benefits of the CDSMP among patients with systemic lupus erythematosus (SLE); however, little is known about predictors of participation among Black women with SLE. We examined factors associated with CDSMP initiation and completion in this population.
Measuring the Impact of MyLupusGuide in Canada: Results of a Randomized Controlled Study
Paul R. Fortin, Carolyn Neville, Anne-Sophie Julien, Elham Rahme, Vinita Haroun, Jodie Nimigon-Young, Anna-Lisa Morrison, Davy Eng, Christine A. Peschken, Evelyne Vinet, Marie Hudson, Doug Smith, Mark Matsos, Janet E. Pope, Ann E. Clarke, Stephanie Keeling, J. Antonio Avina-Zubieta, Murray Rochon, Deborah Da Costa
doi : 10.1002/acr.24871
This study was undertaken to assess the effects of a web-based program, MyLupusGuide, developed to facilitate self-management in systemic lupus erythematosus (SLE).
Digital Narratives of Living With Lupus: Lived Experiences and Meanings for Latin American and Latino Patients and Their Families
Tirsa Colmenares-Roa, Alfonso Gastelum-Strozzi, Erica Crosley, Yurilis Fuentes-Silva, Cristina Reategui-Sokolova, Claudia Elera-Fitzcarrald, Soledad Ibañez, Ernesto Cairoli
doi : 10.1002/acr.24870
Systemic lupus erythematosus (SLE) disproportionately affects Latin American and Latino populations, with worse outcomes compared to nonminority populations.
Pilot Intervention to Improve Medication Adherence Among Patients With Systemic Lupus Erythematosus Using Pharmacy Refill Data
Kai Sun, Amanda M. Eudy, Jennifer L. Rogers, Lisa G. Criscione-Schreiber, Rebecca E. Sadun, Jayanth Doss, Mithu Maheswaranathan, Ann Cameron Barr, Lena Eder, Amy L. Corneli, Hayden B. Bosworth, Megan E. B. Clowse
doi : 10.1002/acr.24806
Despite high rates of medication nonadherence among patients with systemic lupus erythematosus (SLE), effective interventions to improve adherence in SLE are limited. We aimed to assess the feasibility of a pilot intervention and explore its effect on adherence.
Systemic Lupus Erythematosus and Mortality in Elderly Patients With Early Breast Cancer
Sebastian Bruera, Xiudong Lei, Xerxes Pundole, Hui Zhao, Sharon H. Giordano, Surabhi Vinod, Maria E. Suarez-Almazor
doi : 10.1002/acr.24793
Patients with cancer and systemic lupus erythematosus (SLE) may have worse outcomes than those without SLE, given their comorbidities. We examined survival in elderly women with breast cancer (BC) and SLE and hypothesized that survival would be decreased compared with women with BC but without SLE.
Assessing the Utility of the Montreal Cognitive Assessment in Screening for Cognitive Impairment in Patients With Systemic Lupus Erythematosus
Oshrat E. Tayer-Shifman, Kimberley Yuen, Robin Green, Mahta Kakvan, Patricia Katz, Kathleen S. Bingham, Juan Pablo Diaz-Martinez, Lesley Ruttan, Joan E. Wither
doi : 10.1002/acr.24971
Screening for cognitive impairment (CI) in systemic lupus erythematosus (SLE) relies on the American College of Rheumatology (ACR) neuropsychological battery (NB).
Association of the Systemic Lupus International Collaborating Clinics Frailty Index and Damage Accrual in Longstanding Systemic Lupus Erythematosus
Kaitlin Lima, Alexandra Legge, John G. Hanly, Jungwha Lee, Jing Song, Anh Chung, Rosalind Ramsey-Goldman
doi : 10.1002/acr.24798
To externally validate the Systemic Lupus International Collaborating Clinics Frailty Index (SLICC-FI) in a prevalent systemic lupus erythematosus (SLE) cohort and to assess the ability of the SLICC-FI to predict organ damage accrual among individuals with longstanding SLE.
Association of Systemic Lupus International Collaborating Clinics Frailty Index With Damage in Systemic Lupus Erythematosus Patients: Results From a Multiethnic, Multicenter US Cohort of Patients With Lupus
Manuel F. Ugarte-Gil, Jyoti Dubey, Gerald McGwin Jr., John D. Reveille, Luis M. Vilá, Graciela S. Alarcón
doi : 10.1002/acr.24878
To evaluate the association between the Systemic Lupus International Collaborating Clinics frailty index (SLICC-FI) and damage accrual in systemic lupus erythematosus (SLE) patients.
Frequency of Contraception Documentation in Women With Systemic Lupus Erythematosus and Rheumatoid Arthritis Within the Rheumatology Informatics System for Effectiveness Registry
Megan E. B. Clowse, Jing Li, Mehret Birru Talabi, Amanda M. Eudy, Gabriela Schmajuk
doi : 10.1002/acr.24803
We sought to understand the frequency of contraception documentation for women with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) in a large US electronic health record (EHR)–based registry and to identify disparities by teratogen prescription and patient race and ethnicity.
Reduction of Cardiovascular Disease and Mortality Versus Risk of New-Onset Diabetes Mellitus With Statin Use in Patients With Rheumatoid Arthritis
Gulsen Ozen, Sophie Dell'Aniello, Sofia Pedro, Kaleb Michaud, Samy Suissa
doi : 10.1002/acr.24866
To assess the effect of statin use on the risk of cardiovascular disease (CVD), all-cause mortality, and type 2 diabetes mellitus (DM) in patients with rheumatoid arthritis (RA).
Development of a Natural Language Processing System for Extracting Rheumatoid Arthritis Outcomes From Clinical Notes Using the National Rheumatology Informatics System for Effectiveness Registry
Marie Humbert-Droz, Zara Izadi, Gabriela Schmajuk, Milena Gianfrancesco, Matthew C. Baker, Jinoos Yazdany, Suzanne Tamang
doi : 10.1002/acr.24869
To accelerate the use of outcome measures in rheumatology, we developed and evaluated a natural language processing (NLP) pipeline for extracting these measures from free-text outpatient rheumatology notes within the American College of Rheumatology's Rheumatology Informatics System for Effectiveness (RISE) registry.
Adipocytokines and Associations With Abnormal Body Composition in Rheumatoid Arthritis
Joshua F. Baker, Patricia Katz, David R. Weber, Patrick Gould, Michael D. George, Jin Long, Babette S. Zemel, Jon T. Giles
doi : 10.1002/acr.24790
We determined associations between adipokines and abnormal body composition in patients with rheumatoid arthritis (RA).
Are We on the Same Page? A Cross-Sectional Study of Patient–Clinician Goal Concordance in Rheumatoid Arthritis
Jennifer L. Barton, Sheila Markwardt, Meike Niederhausen, Allison Schue, Jacob Dougherty, Patricia Katz, Somnath Saha, Edward H. Yelin
doi : 10.1002/acr.24794
Patient–clinician goal concordance is associated with improved outcomes in certain chronic diseases but not explored in rheumatoid arthritis (RA). We examined goal concordance, correlates of concordance, and the association of concordance with health outcomes.
Implementing a Virtual Flipped Classroom in a Rheumatology Fellowship Program
Stefanie D. Wade, Jason A. Freed, Vasileios C. Kyttaris, Staci Saunders, Jonathan S. Hausmann
doi : 10.1002/acr.24791
Active learning opportunities within graduate medical education may be underused. We aimed to assess whether active learning strategies increase after implementing a faculty development workshop and transitioning rheumatology fellowship didactics to a virtual flipped classroom.
Damage Trajectories in Systemic Sclerosis Using Group-Based Trajectory Modeling
Ariane Barbacki, Murray Baron, Mianbo Wang, Yuqing Zhang, Wendy Stevens, Joanne Sahhar, Susanna Proudman, Mandana Nikpour, Ada Man, on behalf of the Australian Scleroderma Interest Group and the Canadian Scleroderma Research Group
doi : 10.1002/acr.24873
Systemic sclerosis (SSc) is an autoimmune disease characterized by progressive organ damage, which can be measured using the Scleroderma Clinical Trials Consortium Damage Index (SCTC-DI). We aimed to identify whether distinct trajectories of damage accrual exist and to determine which variables are associated with different trajectory groups.
Blood Neutrophil Count and Neutrophil-to-Lymphocyte Ratio for Prediction of Disease Progression and Mortality in Two Independent Systemic Sclerosis Cohorts
Nancy Wareing, Vishnu Mohan, Rana Taherian, Elizabeth R. Volkmann, Marka A. Lyons, Holly Wilhalme, Michael D. Roth, Rosa M. Estrada-y-Martin, Brian Skaug, Maureen D. Mayes, Donald P. Tashkin, Shervin Assassi
doi : 10.1002/acr.24880
To assess the predictive significance of blood neutrophil count and the ratio between neutrophil and lymphocyte count (neutrophil-to-lymphocyte ratio [NLR]) for disease severity and mortality in systemic sclerosis (SSc).
Assessing the Severity of COVID-19 Lung Injury in Rheumatic Diseases Versus the General Population Using Deep Learning–Derived Chest Radiograph Scores
Naomi J. Patel, Kristin M. D'Silva, Matthew D. Li, Tiffany Y. T. Hsu, Michael DiIorio, Xiaoqing Fu, Claire Cook, Lauren Prisco, Lily Martin, Kathleen M. M. Vanni, Alessandra Zaccardelli, Yuqing Zhang, Jayashree Kalpathy-Cramer, Jeffrey A. Sparks, Zachary S. Wallace
doi : 10.1002/acr.24883
COVID-19 patients with rheumatic disease have a higher risk of mechanical ventilation than the general population. The present study was undertaken to assess lung involvement using a validated deep learning algorithm that extracts a quantitative measure of radiographic lung disease severity.
Prevalence of Fibromyalgia Syndrome in Active-Duty Military Personnel
Katrina M. Lawrence-Wolff, Jay B. Higgs, Stacey Young-McCaughan, Jim Mintz, Edna B. Foa, Patricia A. Resick, Kevin M. Kelly, Douglas M. Maurer, Adam M. Borah, Jeffrey S. Yarvis, Brett T. Litz, Bernard A. Hildebrand, Douglas E. Williamson, Alan L. Peterson, for the STRONG STAR Consortium
doi : 10.1002/acr.24801
Previous research with civilian populations has found strong associations between fibromyalgia (FM) and posttraumatic stress disorder (PTSD). We undertook this study to investigate the prevalence of FM in military service members with and without PTSD.
Vitamin D Levels and Risk of Juvenile Idiopathic Arthritis: A Mendelian Randomization Study
Sarah L. N. Clarke, Ruth E. Mitchell, Gemma C. Sharp, Athimalaipet V. Ramanan, Caroline L. Relton
doi : 10.1002/acr.24815
Observational studies report mixed findings regarding the association between vitamin D and juvenile idiopathic arthritis (JIA) incidence or activity; however, such studies are susceptible to considerable bias.
Agreement Among Multiple Observers on Crystal Identification by Synovial Fluid Microscopy
José-Antonio Bernal, Mariano Andrés, Salvador López-Salguero, Vega JovanÃ, Paloma Vela-Casasempere, Eliseo Pascual
doi : 10.1002/acr.24874
Despite the fact that polarized microscopy remains the gold standard for diagnosing crystal arthritis, some uncertainties hamper full implementation in clinical practice. We undertook this study to analyze the agreement among multiple observers in crystal identification using compensated polarized microscopy, as well as to assess potential outcome modifiers.
Implementation of Rheumatology Health Care Transition Processes and Adaptations to Systems Under Stress: A Mixed-Methods Study
Joyce C. Chang, Cora Sears, Nicole Bitencourt, Rosemary Peterson, Risa Alperin, Y. Ingrid Goh, Rebecca S. Overbury, Rebecca Sadun, Emily Smitherman, Patience H. White, Erica F. Lawson, Kristine Carandang
doi : 10.1002/acr.24822
Despite poor health care transition outcomes among young adults with pediatric rheumatic diseases, adoption of transition best practices is low. We sought to understand how structured transition processes were operationalized within pediatric rheumatology practices and what factors were perceived to enable adaptations during a global pandemic.
