Magdalena Wlad a,*, Andreas Frick a, Jonas Engman b, Olof Hjorth b, Johanna M. Hoppe a, Vanda Faria b,c,d, Kurt Wahlstedt b, Johannes Bj ̈orkstrand e, Kristoffer NT Månsson f, Sara Hultberg b, Iman Alaie a,g, J ̈orgen Ros �en h, Mats Fredrikson b, Tomas Furmark b,1, Malin Gingnell
doi : 10.1016/j.bbr.2023.114304
Volume 442, 28 March 2023, 114304
Social anxiety disorder (SAD) is associated with aberrant emotional information processing while little is known about non-emotional cognitive processing biases. The dorsal anterior cingulate cortex (dACC) has been implicated in SAD neuropathology and is activated both by emotional and non-affective cognitive challenges like the Multisource Interference Task (MSIT).
Osman Akan a,*, Anne Bierbrauer b,c, Lukas Kunz d, Patrick D. Gajewski e, Stephan Getzmann e, Jan G. Hengstler e, Edmund Wascher e, Nikolai Axmacher c, Oliver T. Wolf
doi : 10.1016/j.bbr.2023.114305
Volume 442, 28 March 2023, 114305
Repeated exposure to stress (chronic stress) can cause excess levels of circulating cortisol and has detrimental influences on various cognitive functions including long-term memory and navigation.
Cheryl F. Harding a,b,*, David Liao a,c, Ramona Persaud a,c,d, Richard A. DeStefano c,d, Kimberly G. Page b, Lauren L. Stalbow c,f, Tina Roa e, Jordan C. Ford e, Ksenia D. Goman a, Carolyn L. Pytte
doi : 10.1016/j.bbr.2023.114294
Volume 442, 28 March 2023, 114294
People who live or work in moldy buildings often complain of “brain fog� that interferes with cognitive performance. Until recently, there was no published research on the effects of controlled exposure to mold stimuli on cognitive function or an obvious mechanism of action, fueling controversy over these claims.
Marianna Makov Ì�a a, Svatava Kaˇsparov Ì�a a,*, Tom Ì�aˇs TvrdÃk a,b, Mireia Noguera c, KristÃna Beloviˇcov Ì�a c, KristÃna Csatlosov Ì�a c, Michal Dubovický
doi : 10.1016/j.bbr.2023.114296
Volume 442, 28 March 2023, 114296
We aimed to determine, using in vivo magnetic resonance, whether maternal depression induced by chronic unpredictable stress (CUS) in the pre-gestational period in female rats would be evidenced by structural or neurometabolic changes in the hippocampal region of the brain.
Morvarid Meamar a, Ali Rashidy-Pour a,b, Abbas Ali Vafaei a,b,*, Payman Raise-Abdullahi
doi : 10.1016/j.bbr.2023.114310
Volume 442, 28 March 2023, 114310
The extinction of auditory fear conditioning (AFC) refers to reducing the fear responses induced following repeated presentation of a conditioned stimulus (tone) in the absence of an unconditioned stimulus (electric foot shock).
Hannah L. Coyle a,1, Neil W. Bailey a,b,c,*,1, Jennie Ponsford d,e, Kate E. Hoy a,
doi : 10.1016/j.bbr.2023.114308
Volume 442, 28 March 2023, 114308
The ability of the brain to recover following neurological insult is of interest for mild traumatic brain injury (mTBI) populations. Investigating whether non-invasive brain stimulation (NIBS) can modulate neurophysiology and cognition may lead to the development of therapeutic interventions post injury.
Lou-Yan Ma a, Song-fang Liu b, Ya-gang Guo c, Zheng-quan Ma a, Ya Li d, Shu-jin Wang b, Yu Niu b, Mo Li a, Jia-jia Zhai a, Su-hang Shang e, Ya-Li Lv f,*, Qiu-Min Qu
doi : 10.1016/j.bbr.2023.114286
Volume 442, 28 March 2023, 114286
Diabetes has been regarded as an independent risk factor for Alzheimer’s disease (AD). Our previous study found that diabetes activated autophagy, but lysosome function was impaired. Autophagy-lysosome dysfunction may be involved in Aβ deposition in diabetic cognitive impairment.
Nikhil Menon, Caoyuanhui Wang, James A. Carr
doi : 10.1016/j.bbr.2023.114317
Volume 442, 28 March 2023, 114317
Animals will halt foraging efforts and engage defensive behaviors in response to predator cues. Some researchers have proposed that the switch from appetitive to avoidance behavior resembles anxiety, but most work on this has been performed in a limited number of animal models, primarily zebrafish and rodents.
Ziming Liu a,1, Xuanyi Pan a,1, Jiguang Guo b, Liping Li c, Yuxin Tang b, Guangyi Wu a, Ming Li b,*, Hongjie Wang a
doi : 10.1016/j.bbr.2023.114327
Volume 442, 28 March 2023, 114327
Sevoflurane is the primary inhaled anesthetic used in pediatric surgery. It has been the focus of research since animal models studies found that it was neurotoxic to the developing brain two decades ago.
Mareli Roets 1, Linda Brand 2, Stephan F. Steyn
doi : 10.1016/j.bbr.2023.114321
Volume 442, 28 March 2023, 114321
During the peripartum period, women are at an increased risk to develop perinatal distress, presenting as symptoms of depression and/or anxiety. Yet, due to practical and ethical restrictions, our understanding of this condition remains limited.
Kathryn A. McNaughton a, Lauren L. Williamson
doi : 10.1016/j.bbr.2023.114320
Volume 442, 28 March 2023, 114328
In learning and memory tasks, immune overactivation is associated with impaired performance, while normal immune activation is associated with optimal performance. In one specific domain of memory, context discrimination memory, peripheral immune stimulation has been shown to impair performance on the context-object discrimination memory task in male rats.
Jin-Meng Lv a,1, Li-Min Zhang b,*,1, Jie-Xia Wang c, Jing-Jing Shao d, Xin-Gui Guo e, Lu-Ying Wang f, Li-Qing Kang g, Wei-Chao Zheng h, Yue Xin i, Rong-Xin Song j, Wei Guo k, Dong-Xue Zhang
doi : 10.1016/j.bbr.2023.114328
Volume 442, 28 March 2023, 114328
Cognitive impairment, which includes perioperative psychological distress and cognitive dysfunction, can be determined by preoperative and post-operative neuropsychological tests.
Li-Tian Yin a,*,1, Rui-Rui Feng a,1, Xiao-Yan Xie a, Xiao-Rong Yang a, Zhuan-Fang Yang a, Jia-Jia Hu a, Shu-Fen Wu a,b, Ce Zhang
doi : 10.1016/j.bbr.2023.114330
Volume 442, 28 March 2023, 114330
Extracellular matrix proteins appear to be necessary for the synaptic plasticity that underlies addiction memory. In the brain, matrix metalloproteinases (MMPs), especially matrix metalloproteinase-9 (MMP-9), have been recently implicated in processes involving alcohol reward and memory.
Yining Xiao a,b,c, Tianyuan Guan a,b, Xiaofeng Yang a,d, Jing Xu b,c, Jiawei Zhang a, Qianqian Qi a,b, Zhenjie Teng a,b,c, Yanhong Dong b,c, Yaran Gao b, Meixi Li b, Nan Meng b, Peiyuan Lv
doi : 10.1016/j.bbr.2023.114301
Volume 442, 28 March 2023, 114301
One main factor contributing to the cognitive loss in vascular dementia (VD) is white matter lesions (WMLs) carried on by chronic cerebral hypoperfusion (CCH). A secondary neuroinflammatory response to CCH accelerates the loss and limits the regeneration of oligodendrocytes, leading to progressive demyelination and insufficient remyelination in the white matter.
M.M. Hyer 1, A.J. Wegener 1, I. Targett , S.K. Dyer , G.N. Neigh
doi : 10.1016/j.bbr.2023.114323
Volume 442, 28 March 2023, 114323
Prolonged stress beginning in adolescence can contribute to the dysregulation of the neuroendocrine system in adulthood. As the neuroendocrine and neuroimmune systems participate in bi-directional regulatory control, adolescent stress can prime the neuroimmune system to future inflammatory insults.
Ana Cheg ̃ao 1, Hugo Vicente Miranda
doi : 10.1016/j.bbr.2023.114309
Volume 442, 28 March 2023, 114309
We are witnessing a considerable increase in the incidence of Parkinson’s disease (PD), which may be due to the general ageing of the population.
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