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Breaking the Link Between Enrollment in Hospice and Discontinuation of Dialysis
Kai Romero, MD1,2; Eric Widera, MD3,4; Melissa W. Wachterman, MD, MSc, MPH5,6,7
doi : 10.1001/jamainternmed.2022.6390
March 2023, Vol 183, No. 3, Pages 176-278
Redesigning Opioid Pain Agreements to Promote Patient-Centered Care
Michael A. Incze, MD, MSEd1,2
Prevalence of Colorectal Neoplasia 10 or More Years After a Negative Screening Colonoscopy in 120 000 Repeated Screening Colonoscopies
Thomas Heisser, MSc1,2; Jens Kretschmann, MSc3; Bernd Hagen, PhD3; Tobias Niedermaier, PhD1; Michael Hoffmeister, PhD1; Hermann Brenner, MD1,4,5
doi : 10.1001/jamainternmed.2022.6215
Importance Screening colonoscopy to prevent and early detect colorectal cancer is recommended to be repeated in 10-year intervals, which goes along with high demands of capacities and costs. Evidence of findings at screening colonoscopies conducted 10 or more years after a negative colonoscopy result is sparse, and it remains unclear whether screening colonoscopy intervals could possibly be prolonged.
Effect of Disposable Elevator Cap Duodenoscopes on Persistent Microbial Contamination and Technical Performance of Endoscopic Retrograde CholangiopancreatographyThe ICECAP Randomized Clinical Trial
Nauzer Forbes, MD, MSc1,2; B. Joseph Elmunzer, MD, MSc3; Thibault Allain, PhD4; Michael D. Parkins, MD, MSc5,6; Prameet M. Sheth, PhD7,8; Barbara J. Waddell, BSc5; Kristine Du, BSc5; Katya Douchant, MSc7; Olajumoke Oladipo, MSc9; April Saleem, BSc8; Shane Cartwright, BSc1; Millie Chau, BSc1; Megan Howarth, BSc1; Jackie McKay, BSc11; Tamim Nashad, MD1; Yibing Ruan, PhD, MPH10,11; Kirles Bishay, MD, MSc1; Emmanuel Gonzalez-Moreno, MD1; Zhao Wu Meng, BMBS1; Sydney Bass, MD1; Robert Bechara, MD12; Martin J. Cole, MD1; Diederick W. Jalink, MD13; Rachid Mohamed, MD1; Christian Turbide, MD1; Paul J. Belletrutti, MD1; Ahmed Kayal, MD, MSc1; Puja R. Kumar, MD1; Robert J. Hilsden, MD, PhD1,2; André G. Buret, PhD4; Lawrence Hookey, MD12; Steven J. Heitman, MD, MSc1,2
doi : 10.1001/jamainternmed.2022.6394
Importance Infection transmission following endoscopic retrograde cholangiopancreatography (ERCP) can occur due to persistent contamination of duodenoscopes despite high-level disinfection to completely eliminate microorganisms on the instrument.
Chest Pain Management Using Prehospital Point-of-Care Troponin and Paramedic Risk Assessment
Luke P. Dawson, MBBS, MPH1,2,3; Emily Nehme, MBiostats2,4; Ziad Nehme, PhD2,4,5; Ella Zomer, PhD2; Jason Bloom, MBBS1,6; Shelley Cox, PhD2,4; David Anderson, MBChB4,5,7; Michael Stephenson, BHlthSci, GradDipHlthSci2,4,5; Jocasta Ball, PhD2; Jennifer Zhou, MBBS1; Jeffrey Lefkovits, MBBS2,3; Andrew J. Taylor, MBBS, PhD1,8; Mark Horrigan, MBBS9,10; Derek P. Chew, MBBS, MPH, PhD11; David Kaye, MBBS, PhD1,6; Louise Cullen, MBBS, PhD12; Cathrine Mihalopoulos, PhD2; Karen Smith, PhD2,4,5; Dion Stub, MBBS, PhD1,2,6
doi : 10.1001/jamainternmed.2022.6409
Importance Prehospital point-of-care troponin testing and paramedic risk stratification might improve the efficiency of chest pain care pathways compared with existing processes with equivalent health outcomes, but the association with health care costs is unclear.
Effect of Antibiotic Prescription Audit and Feedback on Antibiotic Prescribing in Primary CareA Randomized Clinical Trial
Soheila Aghlmandi, PhD1; Florian S. Halbeisen, PhD1; Ramon Saccilotto, MD2; Pascal Godet3; Andri Signorell4; Simon Sigrist5; Dominik Glinz, PhD1; Giusi Moffa, PhD6; Andreas Zeller, MD7; Andreas F. Widmer, MD, MSc8; Andreas Kronenberg, MD9; Julia Bielicki, MD, PhD10,11; Heiner C. Bucher, MD, MPH1
doi : 10.1001/jamainternmed.2022.6529
Importance Antibiotics are commonly prescribed in primary care, increasing the risk of antimicrobial resistance in the population.
Deprescribing Medications Among Older Adults From End of Hospitalization Through Postacute CareA Shed-MEDS Randomized Clinical Trial
Eduard E. Vasilevskis, MD, MPH1,2,3,4; Avantika Saraf Shah, MPH1; Emily Kay Hollingsworth, MSW1; Matthew Stephen Shotwell, PhD5; Sunil Kripalani, MD, MSc1,3,4; Amanda S. Mixon, MD, MS, MSPH1,2,3,4; Sandra F. Simmons, PhD1,2,4,6
doi : 10.1001/jamainternmed.2022.6545
Importance Deprescribing is a promising approach to addressing the burden of polypharmacy. Few studies have initiated comprehensive deprescribing in the hospital setting among older patients requiring ongoing care in a postacute care (PAC) facility.
Adherence to Healthy Lifestyle Prior to Infection and Risk of Post–COVID-19 Condition
Siwen Wang, MD1; Yanping Li, PhD1; Yiyang Yue, MS1; Changzheng Yuan, ScD1,2; Jae Hee Kang, ScD3; Jorge E. Chavarro, MD, ScD1,3,4; Shilpa N. Bhupathiraju, PhD1,3; Andrea L. Roberts, PhD5
doi : 10.1001/jamainternmed.2022.6555
Importance Few modifiable risk factors for post–COVID-19 condition (PCC) have been identified.
Comparing Effectiveness and Safety of SGLT2 Inhibitors vs DPP-4 Inhibitors in Patients With Type 2 Diabetes and Varying Baseline HbA1c Levels
Elvira D’Andrea, MD, PhD1; Deborah J. Wexler, MD, MSc2; Seoyoung C. Kim, MD, ScD1; Julie M. Paik, MD, ScD, MPH1,3,4; Ethan Alt, PhD1; Elisabetta Patorno, MD, DrPH1
doi : 10.1001/jamainternmed.2022.6664
Importance Sodium-glucose cotransporter 2 inhibitor (SGLT2i) therapy has been associated with cardiovascular benefits and a few adverse events; however, whether the comparative effectiveness and safety profiles vary with differences in baseline hemoglobin A1c (HbA1c) levels is unknown.
Are We Ready for Prehospital Troponin Testing?
Isabel R. Ostrer, MD1; Tracy Y. Wang, MD, MHS, MSc2,3
Duodenoscopes With Disposable Elevator Caps—An Incremental Reduction in Infection Risk for Patients
Melinda Wang, MD1; Graham M. Snyder, MD, SM2,3
Simplicity Matters—Overengineering Feedback Can Be Counterproductive
Jeffrey A. Linder, MD, MPH1; Craig R. Fox, PhD2
Dr Herman A. Barnett, Black Civil Rights Activists, and the Desegregation of The University of Texas Medical Branch in 1949“We Ought to Go in Texas and I Don’t Mean to a Segregated Medical School�
Vanessa Northington Gamble, MD, PhD1
Self-reported Sexual Harassment and Subsequent Reporting Among Internal Medicine Residency Trainees in the US
Elizabeth M. Viglianti, MD, MPH, MSc1; Lisa M. Meeks, PhD2; Andrea L. Oliverio, MD, MSc3; Kathleen Tiffany Lee, MPH1; Theodore J. Iwashyna, MD, PhD4; Susan T. Hingle, MD5
Trends in FDA Adverse Events Reporting for Inferior Vena Cava Filters and Estimated Insertions in the US, 2016 to 2020
Rachel E. Warren, BA1; Sanket S. Dhruva, MD, MHS2,3,4; Madris Kinard, MBA5; John M. Neuhaus, PhD4,6; Rita F. Redberg, MD2,3,4,7
Effect of Moderate and Vigorous Aerobic Exercise on Incident Diabetes in Adults With ObesityA 10-Year Follow-up of a Randomized Clinical Trial
Ying Chen, MD, PhD1; Zheng Chen, MD2; Lingling Pan, MD, PhD3; Zhi-Min Ma, MD, PhD4; Huijie Zhang, MD, PhD5; Xue-Jun Li, MD, PhD2; Xiaoying Li, MD, PhD1,6
Estimated Medicaid Spending on Original and Citrate-Free Adalimumab From 2014 Through 2021
Junyi Wang, MS1; ChangWon C. Lee, AB1; Aaron S. Kesselheim, MD, JD, MPH1; Benjamin N. Rome, MD, MPH1
Does ST Elevation in Lead aVR Require an Emergent Trip to the Catheterization Laboratory?
Michael Brouner, MD1; Jamey Hammock, MD2; Harish Doppalapudi, MD3
A Paradoxical ST-Segment Elevation Distribution Rendering a Challenging Prediction of the Culprit Vessel in Acute Myocardial Infarction
Ruihai Zhou, MSc, MD, RPVI1
Ominous Electrocardiographic Patterns in an Older Adult With Chest Pain
Zhangli Yang, MD1; Chuan-Hai Zhang, MD2; Xuanxuan Li, MD3
Wide QRS Complex Tachycardia Change to Narrow QRS Complex Tachycardia After β-Blocker Administration
Jun-Peng Liu, MD, PhD1; Wen-Duo Zhang, MD, PhD1; Hua Wang, MD1
Caution With Conclusions and Context of Mechanical Circulatory Devices
Christophe Vandenbriele, MD, PhD1; Guido Tavazzi, MD, PhD2; Susanna Price, MD, PhD3
Caution With Conclusions and Context of Mechanical Circulatory Devices—Reply
P. Elliott Miller, MD, MHS1; Nihar R. Desai, MD, MPH1
