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Is Anxiety in Late Life an Uncharted Territory?—Questioning the USPSTF Draft Recommendation Statement for Anxiety Screening in Older Adults
Carmen Andreescu, MD1; Eric Lenze, MD2; Helen Lavretsky, MD, MS3
doi : 10.1001/jamapsychiatry.2022.4609
March 2023, Vol 80, No. 3, Pages 196-279
Addressing Dementia-Related Behaviors Before, During, and After the Pandemic—Disrupting the Behavior-to-Prescribing Reflex
Helen C. Kales, MD1; Donovan T. Maust, MD2; Laura N. Gitlin, PhD3
Sleep Abnormalities in Different Clinical Stages of PsychosisA Systematic Review and Meta-analysis
Joëlle Bagautdinova, MSc1; Ahmad Mayeli, PhD2; James D. Wilson, PhD2; Francesco L. Donati, MD2,3; Rebekah M. Colacot, BS4; Nicholas Meyer, MD, PhD5; Paolo Fusar-Poli, MD, PhD6,7; Fabio Ferrarelli, MD, PhD2
doi : 10.1001/jamapsychiatry.2022.4599
Importance Abnormal sleep is frequent in psychosis; however, sleep abnormalities in different stages (ie, clinical high risk for psychosis [CHR-P], early psychosis [EP], and chronic psychosis [CP]) have not been characterized.
Rates of Antipsychotic Drug Prescribing Among People Living With Dementia During the COVID-19 Pandemic
Hao Luo, PhD1,2,3; Wallis C. Y. Lau, PhD4,5,6; Yi Chai, PhD5; Carmen Olga Torre, MSc7,8,9; Robert Howard, MD10; Kathy Y. Liu, PhD10; Xiaoyu Lin, MSc11; Can Yin, MSc11; Stephen Fortin, PharmD12; David M. Kern, PhD13; Dong Yun Lee, MD14; Rae Woong Park, PhD14; Jae-Won Jang, MD15; Celine S. L. Chui, PhD6,16,17; Jing Li, MSc11; Christian Reich, PhD11; Kenneth K. C. Man, PhD4,5,6; Ian C. K. Wong, PhD4,18
doi : 10.1001/jamapsychiatry.2022.4448
Importance Concerns have been raised that the use of antipsychotic medication for people living with dementia might have increased during the COVID-19 pandemic.
Utility of Wrist-Wearable Data for Assessing Pain, Sleep, and Anxiety Outcomes After Traumatic Stress Exposure
Laura D. Straus, PhD1,2; Xinming An, PhD3; Yinyao Ji, MS4; Samuel A. McLean, MD, MPH4,5; Thomas C. Neylan, MD2,6; and the AURORA Study Group
doi : 10.1001/jamapsychiatry.2022.4533
Importance Adverse posttraumatic neuropsychiatric sequelae after traumatic stress exposure are common and have higher incidence among socioeconomically disadvantaged populations.
Evaluation of a Model to Target High-risk Psychiatric Inpatients for an Intensive Postdischarge Suicide Prevention Intervention
Ronald C. Kessler, PhD1; Mark S. Bauer, MD2,3; Todd M. Bishop, PhD4,5; Robert M. Bossarte, PhD4,6; Victor M. Castro, MS7; Olga V. Demler, PhD8,9; Sarah M. Gildea, BS1; Joseph L. Goulet, PhD10,11; Andrew J. King, MS1; Chris J. Kennedy, PhD2,12; Sara J. Landes, PhD13,14; Howard Liu, SD1,4; Alex Luedtke, PhD15,16; Patrick Mair, PhD17; Brian P. Marx, PhD18,19; Matthew K. Nock, PhD17; Maria V. Petukhova, PhD1; Wilfred R. Pigeon, PhD4,5; Nancy A. Sampson, BA1; Jordan W. Smoller, MD, ScD2,12,20,21,22; Aletha Miller, PhD23; Gretchen Haas, PhD24,25; Jeffrey Benware, PhD26; John Bradley, MD2,3; Richard R. Owen, MD27,28; Samuel House, MD27,28; Snezana Urosevic, PhD29,30; Lauren M. Weinstock, PhD31
doi : 10.1001/jamapsychiatry.2022.4634
Importance The months after psychiatric hospital discharge are a time of high risk for suicide. Intensive postdischarge case management, although potentially effective in suicide prevention, is likely to be cost-effective only if targeted at high-risk patients.
Relationship of Family Genetic Risk Score With Diagnostic Trajectory in a Swedish National Sample of Incident Cases of Major Depression, Bipolar Disorder, Other Nonaffective Psychosis, and Schizophrenia
Kenneth S. Kendler, MD1,2; Henrik Ohlsson, PhD3; Jan Sundquist, MD, PhD3,4,5; Kristina Sundquist, MD, PhD3,4,5
doi : 10.1001/jamapsychiatry.2022.4676
Importance Since its inception under Kraepelin in the modern era, diagnostic stability and familial/genetic risk have been among the most important psychiatric nosologic validators.
Lipid Alteration Signature in the Blood Plasma of Individuals With Schizophrenia, Depression, and Bipolar Disorder
Anna Tkachev, PhD1,2; Elena Stekolshchikova, PhD1; Anna Vanyushkina, PhD1; Hanping Zhang, PhD3,4; Anna Morozova, MD, PhD5,6; Svetlana Zozulya, MD, PhD7; Ilia Kurochkin, PhD1; Nickolay Anikanov, MSc1; Alina Egorova, MSc1; Ekaterina Yushina, MSc1,8; Thomas Vogl, MSc9; Fanny Senner, MD9,10; Sabrina K. Schaupp, MSc9; Daniela Reich-Erkelenz, MSc9; Sergi Papiol, PhD9,10; Mojtaba Oraki Kohshour, MSc9,11; Farahnaz Klöhn-Saghatolislam, MD9; Janos L. Kalman, MD, PhD9,10; Urs Heilbronner, PhD9; Maria Heilbronner, MSc9; Katrin Gade, MD12; Ashley L. Comes, PhD9; Monika Budde, PhD9; Heike Anderson-Schmidt, MD, PhD12; Kristina Adorjan, MD9,10; Jens Wiltfang, MD12,13,14; Eva Z. Reininghaus, MD15; Georg Juckel, MD16; Udo Dannlowski, PhD17; Andreas Fallgatter, MD18; Carsten Spitzer, MD19; Max Schmauß, MD20; Martin von Hagen, MD21; Yana Zorkina, MD, PhD5,6; Alexander Reznik, MD, PhD6,22; Aleksandra Barkhatova, MD, PhD7; Roman Lisov, MSc2,23; Nikita Mokrov, MSc23,24; Maxim Panov, PhD25; Dmitri Zubkov, MSc1; Daria Petrova, PhD1; Chanjuan Zhou, PhD3,26; Yiyun Liu, PhD3; Juncai Pu, PhD3; Peter Falkai, MD10; Georgiy Kostyuk, MD, PhD6; Tatiana Klyushnik, MD, PhD7; Thomas G. Schulze, MD9,27,28; Peng Xie, MD3,4,29; Eva C. Schulte, MD, PhD9,10,30; Philipp Khaitovich, PhD1
doi : 10.1001/jamapsychiatry.2022.4350
Importance No clinically applicable diagnostic test exists for severe mental disorders. Lipids harbor potential as disease markers.
Etiology of the Broad Avoidant Restrictive Food Intake Disorder Phenotype in Swedish Twins Aged 6 to 12 Years
Lisa Dinkler, PhD1; Marie-Louis Wronski, MSc1,2,3; Paul Lichtenstein, PhD1; Sebastian Lundström, PhD4; Henrik Larsson, PhD1,5; Nadia Micali, PhD6,7; Mark J. Taylor, PhD1; Cynthia M. Bulik, PhD1,8,9
doi : 10.1001/jamapsychiatry.2022.4612
Importance Avoidant restrictive food intake disorder (ARFID) is characterized by an extremely limited range and/or amount of food eaten, resulting in the persistent failure to meet nutritional and/or energy needs. Its etiology is poorly understood, and knowledge of genetic and environmental contributions to ARFID is needed to guide future research.
US Religious Leaders’ Views on the Etiology and Treatment of Depression
Anna Holleman, PhD1,2; Mark Chaves, PhD2,3,4
doi : 10.1001/jamapsychiatry.2022.4525
Importance Religious leaders commonly provide assistance to people with mental illness, but little is known about clergy views regarding mental health etiology and appropriate treatment.
Why Hippocampal Glutamate Levels Are Elevated in Schizophrenia
Jia Guo, PhD1; Douglas L. Rothman, PhD2; Scott A. Small, MD1
Years of Life Lost to Drug Overdose Among Black Female Individuals in the US, 2015-2021
Rebecca Arden Harris, MD, MSc1,2; David S. Mandell, ScD2,3
Differences in Insurance Coverage for Individuals With Schizophrenia After Implementation of the Patient Protection and Affordable Care Act
Kimberley H. Geissler, PhD1; Keith M. Ericson, PhD2,3; Gregory E. Simon, MD, MPH4; Jing Qian, PhD1; John E. Zeber, PhD1
