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Aims+Scope/Editorial Board/Publication information
doi : 10.1016/S0167-8140(23)00101-9
Volume 180, March 2023, 109563
High versus standard radiation dose of definitive concurrent chemoradiotherapy for esophageal cancer: A systematic review and meta-analysis of randomized clinical trials
Xiaofeng Wang a,1 , Hui Bai b,1 , Rui Li c,1 , Lide Wang d , Wencheng Zhang a , Jun Liang e,f,⇑, Zhiyong Yuan
doi : 10.1016/j.radonc.2023.109463
Volume 180, March 2023, 109463
Objectives: Compare the efficacy and safety of high vs standard radiation dose of definitive concurrent chemoradiotherapy (dCCRT) for esophageal cancer (EC).
Radiation dose to heart and cardiac substructures and risk of coronary artery disease in early breast cancer patients: A DBCG study based on modern radiation therapy techniques
Marie Louise Holm Milo a,b,⇑, Ditte Slot Møller c,d , Tine Bisballe Nyeng c , Lone Hoffmann c,d , Henrik Dahl Nissen e , Ingelise Jensen f , Ebbe Laugaard Lorenzen g , Lise Bech Jellesmark Thorsen a,h , Kirsten Melgaard Nielsen i , Søren Paaske Johnsen j , Jan Brink Valentin j , Jan Alsner a , Birgitte Vrou Offersen
doi : 10.1016/j.radonc.2022.109453
Volume 180, March 2023, 109453
Coronary artery disease (CAD) has been reported as a late effect following radiation therapy (RT) of early breast cancer (BC). This study aims to report individual RT doses to the heart and cardiac substructures in patients treated with CT-based RT and to investigate if a dose–response relationship between RT dose and CAD exists using modern radiation therapy techniques.
Validation of the 18F-FDG PET image biomarker model predicting late xerostomia after head and neck cancer radiotherapy
Yan Li a,⇑, Nanna Maria Sijtsema a , Suzanne Petronella Maria de Vette a , Roel Johannes Henricus Marinus Steenbakkers a , Fan Zhang b , Walter Noordzij c , Lisa Van den Bosch a , Johannes Albertus Langendijk a , Lisanne Vania van Dijk
doi : 10.1016/j.radonc.2022.109458
Volume 180, March 2023, 109458
Previously, PET image biomarkers (PET-IBMs) – the 90th percentile standardized uptake value (P90-SUV) and the Mean SUV (Mean-SUV) of the contralateral parotid gland (cPG) – were identified as predictors for late-xerostomia following head and neck cancer (HNC) radiotherapy.
Deep learning-based accurate delineation of primary gross tumor volume of nasopharyngeal carcinoma on heterogeneous magnetic resonance imaging: A large-scale and multi-center study
Xiangde Luo a,c , Wenjun Liao a,b,⇑, Yuan He f , Fan Tang g , Mengwan Wu b , Yuanyuan Shen b , Hui Huang h , Tao Song d , Kang Li e , Shichuan Zhang a,b , Shaoting Zhang a,c , Guotai Wang a,
doi : 10.1016/j.radonc.2023.109480
Volume 180, March 2023, 109480
The problem of obtaining accurate primary gross tumor volume (GTVp) segmentation for nasopharyngeal carcinoma (NPC) on heterogeneous magnetic resonance imaging (MRI) images with deep learning remains unsolved. Herein, we reported a new deep-learning method than can accurately delineate GTVp for NPC on multi-center MRI scans.
Tumor volume definitions in head and neck squamous cell carcinoma – Comparing PET/MRI and histopathology
Emmanouil Terzidis a,e , Jeppe Friborg a , Ivan R. Vogelius a , Giedrius Lelkaitis b , Christian von Buchwald c , Anders B. Olin d , Helle H. Johannesen d , Barbara M. Fischer d,f , Irene Wessel c , Jacob H. Rasmussen
doi : 10.1016/j.radonc.2023.109484
Volume 180, March 2023, 109484
In cancer treatment precise definition of the tumor volume is essential, but despite development in imaging modalities, this remains a challenge. Here, pathological tumor volumes from the surgical specimens were obtained and compared to tumor volumes defined from modern PET/MRI hybrid imaging.
Dysphagia and shortness-of-breath as markers for treatment failure and survival in oropharyngeal cancer after radiation
Jarey H. Wang a,b,⇑, Vivian Salama a , Lance McCoy a,c , Cem Dede a , Temitayo Ajayi d , Amy Moreno a , Abdallah S.R. Mohamed a , Katherine A. Hutcheson a,e , Clifton David Fuller a , Lisanne V. van Dijk a,f , On behalf of MD Anderson Head and Neck Symptom Working Group
doi : 10.1016/j.radonc.2023.109465
Volume 180, March 2023, 109465
Post-treatment symptoms are a focal point of follow-up visits for head and neck cancer patients. While symptoms such as dysphagia and shortness-of-breath early after treatment may motivate additional work up, their precise association with disease control and survival outcomes is not well established.
Impact of interstitial lung abnormality on survival after adjuvant durvalumab with chemoradiotherapy for locally advanced non-small cell lung cancer
Tairo Kashihara a,⇑, Yuko Nakayama a , Kae Okuma a , Ayaka Takahashi a , Tomoya Kaneda a , Mika Katagiri a , Hiroki Nakayama a , Yuko Kubo c , Kimiteru Ito c , Satoshi Nakamura a , Kana Takahashi a , Koji Inaba a , Naoya Murakami a , Tetsuo Saito d , Hiroyuki Okamoto a , Jun Itami a , Masahiko Kusumoto c , Yuichiro Ohe b , Hiroshi Igaki
doi : 10.1016/j.radonc.2022.109454
Volume 180, March 2023, 109454
Concurrent chemoradiotherapy (CCRT) has been the standard of care for patients with locally advanced non-small cell lung cancer (LA-NSCLC).
Aims+Scope/Editorial Board/Publication information
doi : 10.1016/S0167-8140(23)00101-9
Volume 180, March 2023, 109563
Survival prediction for stage I-IIIA non-small cell lung cancer using deep learning
Sunyi Zheng a,b,c,⇑, Jiapan Guo a,d , Johannes A. Langendijk a , Stefan Both a , Raymond N.J. Veldhuis e , Matthijs Oudkerk f , Peter M.A. van Ooijen a , Robin Wijsman a , Nanna M. Sijtsema
doi : 10.1016/j.radonc.2023.109483
Volume 180, March 2023, 109483
The aim of this study was to develop and evaluate a prediction model for 2-year overall survival (OS) in stage I-IIIA non-small cell lung cancer (NSCLC) patients who received definitive radiotherapy by considering clinical variables and image features from pre-treatment CT-scans.
Visualization of tumor hypoxia and re-oxygenation after stereotactic body radiation therapy in early peripheral lung cancer: A prospective study
Masahiro Inada a,⇑, Yasumasa Nishimura a , Kohei Hanaoka b , Kiyoshi Nakamatsu a , Hiroshi Doi a , Takuya Uehara a , Mikihito Komanishi b , Kazunari Ishii c , Hayato Kaida c , Makoto Hosono
doi : 10.1016/j.radonc.2023.109491
Volume 180, March 2023, 109491
In this study, fluoromisonidazole positron emission tomography (F-MISO PET/CT) was used to evaluate tumor hypoxia and re-oxygenation in patients with lung tumors treated with stereotactic body radiation therapy (SBRT).
High versus standard radiation dose of definitive concurrent chemoradiotherapy for esophageal cancer: A systematic review and meta-analysis of randomized clinical trials
Xiaofeng Wang a,1 , Hui Bai b,1 , Rui Li c,1 , Lide Wang d , Wencheng Zhang a , Jun Liang e,f,⇑, Zhiyong Yuan
doi : 10.1016/j.radonc.2023.109463
Volume 180, March 2023, 109463
Objectives: Compare the efficacy and safety of high vs standard radiation dose of definitive concurrent chemoradiotherapy (dCCRT) for esophageal cancer (EC).
Survival benefit of radiotherapy following narrow-margin hepatectomy in patients with hepatocellular carcinoma: A propensity score-matched analysis based on phase II study
Liuhua Long a,b,1 , Bo Chen b,1 , Hongzhi Wang a,1 , Yuting Zhao a,1 , Fan Wu c , Liming Wang c , Weiqi Rong c , Jianxiong Wu c , Yexiong Li b,⇑, Weihu Wang
doi : 10.1016/j.radonc.2022.109462
Volume 180, March 2023, 109462
We evaluated the postoperative radiotherapy (PORT) effects on hepatocellular carcinoma (HCC) prognosis and recurrence in patients who underwent narrow-margin (<1.0Â cm) hepatectomy (NH).
Radiation dose to heart and cardiac substructures and risk of coronary artery disease in early breast cancer patients: A DBCG study based on modern radiation therapy techniques
Marie Louise Holm Milo a,b,⇑, Ditte Slot Møller c,d , Tine Bisballe Nyeng c , Lone Hoffmann c,d , Henrik Dahl Nissen e , Ingelise Jensen f , Ebbe Laugaard Lorenzen g , Lise Bech Jellesmark Thorsen a,h , Kirsten Melgaard Nielsen i , Søren Paaske Johnsen j , Jan Brink Valentin j , Jan Alsner a , Birgitte Vrou Offersen
doi : 10.1016/j.radonc.2022.109453
Volume 180, March 2023, 109453
Coronary artery disease (CAD) has been reported as a late effect following radiation therapy (RT) of early breast cancer (BC). This study aims to report individual RT doses to the heart and cardiac substructures in patients treated with CT-based RT and to investigate if a dose–response relationship between RT dose and CAD exists using modern radiation therapy techniques.
Outcomes following brachytherapy boost for intermediate- and high-risk prostate cancer: A retrospective bicenter study by the SFRO brachytherapy group
Kanta Ka a , Renaud Schiappa b , Mario Terlizzi a , Frederic Mallet c , Etienne Martin d , Marie-Eve Chand b , Nicolas Demogeot e , Didier Peiffert e , Pascal Pommier f , Magali Quivrin d , Manon Kissel g , Corentin Pasquier h , Jonathan Khalifa h , Alberto Bossi a , Jean-Michel Hannoun-Levi b , Pierre Blanchard
doi : 10.1016/j.radonc.2022.109460
Volume 180, March 2023, 109460
Radiotherapy dose escalation improves biochemical control in intermediate- or high-risk prostate cancer. Brachytherapy boost was shown to further improve biochemical control compared to radiotherapy alone in three randomized trials. The SFRO brachytherapy group sought to evaluate the efficacy and toxicity of BT-boost for intermediate and high-risk prostate cancer in real life, and to determine prognostic factors for efficacy and toxicity.
Validation of the 18F-FDG PET image biomarker model predicting late xerostomia after head and neck cancer radiotherapy
Yan Li a,⇑, Nanna Maria Sijtsema a , Suzanne Petronella Maria de Vette a , Roel Johannes Henricus Marinus Steenbakkers a , Fan Zhang b , Walter Noordzij c , Lisa Van den Bosch a , Johannes Albertus Langendijk a , Lisanne Vania van Dijk
doi : 10.1016/j.radonc.2022.109458
Volume 180, March 2023, 109458
Previously, PET image biomarkers (PET-IBMs) – the 90th percentile standardized uptake value (P90-SUV) and the Mean SUV (Mean-SUV) of the contralateral parotid gland (cPG) – were identified as predictors for late-xerostomia following head and neck cancer (HNC) radiotherapy.
Recurrence characteristics after focal salvage HDR brachytherapy in prostate cancer
Marnix J.A. Rasing a,⇑, Max Peters a , Marieke van Son b , Marinus A. Moerland a , Wietse Eppinga a , Sandrine M.G. van de Pol a , Juus Noteboom a , Jan Lagendijk a , Jochem R.N. van der Voort van Zyp
doi : 10.1016/j.radonc.2023.109495
Volume 180, March 2023, 109495
Radiorecurrent prostate cancer is often confined to the prostate, predominantly near the index lesion. The purpose of this study was to look at recurrence characteristics in patients treated with focal salvage high dose-rate (HDR) brachytherapy.
Deep learning-based accurate delineation of primary gross tumor volume of nasopharyngeal carcinoma on heterogeneous magnetic resonance imaging: A large-scale and multi-center study
Xiangde Luo a,c , Wenjun Liao a,b,⇑, Yuan He f , Fan Tang g , Mengwan Wu b , Yuanyuan Shen b , Hui Huang h , Tao Song d , Kang Li e , Shichuan Zhang a,b , Shaoting Zhang a,c , Guotai Wang a,
doi : 10.1016/j.radonc.2023.109480
Volume 180, March 2023, 109480
The problem of obtaining accurate primary gross tumor volume (GTVp) segmentation for nasopharyngeal carcinoma (NPC) on heterogeneous magnetic resonance imaging (MRI) images with deep learning remains unsolved. Herein, we reported a new deep-learning method than can accurately delineate GTVp for NPC on multi-center MRI scans.
Interobserver variation in clinical target volume (CTV) delineation for stereotactic radiotherapy to non-spinal bone metastases in prostate cancer: CT, MRI and PET/CT fusion
Ewan Richard Chapman a,c,⇑, Luke Nicholls d,e , Yae-Eun Suh b , Vincent Khoo b,c , Daniel Levine b , Derfel ap Dafydd b , Nicholas Van As
doi : 10.1016/j.radonc.2022.109461
Volume 180, March 2023, 109461
The use of SBRT for the treatment of oligometastatic prostate cancer is increasing rapidly. While consensus guidelines are available for non-spinal bone metastases practice continues to vary widely. The aim of this study is to look at inter-observer variability in the contouring of prostate cancer non-spinal bone metastases with different imaging modalities.
Tumor volume definitions in head and neck squamous cell carcinoma – Comparing PET/MRI and histopathology
Emmanouil Terzidis a,e , Jeppe Friborg a , Ivan R. Vogelius a , Giedrius Lelkaitis b , Christian von Buchwald c , Anders B. Olin d , Helle H. Johannesen d , Barbara M. Fischer d,f , Irene Wessel c , Jacob H. Rasmussen
doi : 10.1016/j.radonc.2023.109484
Volume 180, March 2023, 109484
In cancer treatment precise definition of the tumor volume is essential, but despite development in imaging modalities, this remains a challenge. Here, pathological tumor volumes from the surgical specimens were obtained and compared to tumor volumes defined from modern PET/MRI hybrid imaging.
Evaluation of therapeutic radiographer contouring for magnetic resonance image guided online adaptive prostate radiotherapy
Gillian Adair Smith a,⇑, Alex Dunlop c , Sophie E. Alexander b , Helen Barnes a , Francis Casey c , Joan Chick c , Ranga Gunapala d , Trina Herbert a , Rebekah Lawes a , Sarah A. Mason c , Adam Mitchell c , Jonathan Mohajer c , Julia Murray b , Simeon Nill c , Priyanka Patel b , Angela Pathmanathan b , Kobika Sritharan b , Nora Sundahl b , Alison C. Tree b , Rosalyne Westley b , Bethany Williams a , Helen A. McNair
doi : 10.1016/j.radonc.2022.109457
Volume 180, March 2023, 109457
The implementation of MRI-guided online adaptive radiotherapy has facilitated the extension of therapeutic radiographers’ roles to include contouring, thus releasing the clinician from attending daily treatment. Following undergoing a specifically designed training programme, an online interobserver variability study was performed.
Dysphagia and shortness-of-breath as markers for treatment failure and survival in oropharyngeal cancer after radiation
Jarey H. Wang a,b,⇑, Vivian Salama a , Lance McCoy a,c , Cem Dede a , Temitayo Ajayi d , Amy Moreno a , Abdallah S.R. Mohamed a , Katherine A. Hutcheson a,e , Clifton David Fuller a , Lisanne V. van Dijk a,f , On behalf of MD Anderson Head and Neck Symptom Working Group
doi : 10.1016/j.radonc.2023.109465
Volume 180, March 2023, 109465
Post-treatment symptoms are a focal point of follow-up visits for head and neck cancer patients. While symptoms such as dysphagia and shortness-of-breath early after treatment may motivate additional work up, their precise association with disease control and survival outcomes is not well established.
The risk of valvular heart disease in the French Childhood Cancer Survivors’ Study: Contribution of dose-volume histogram parameters
Stefania Chounta a,b,c,d , Sarah Lemler d , Nadia Haddy a,b,c , Brice Fresneau e , Imene Mansouri a,b,c,f,g , Mahmoud Bentriou d , Charlotte Demoor-Goldschmidt a,b,c,h , Ibrahima Diallo i,j , Vincent Souchard a,b,c , Thi-Duyen Do a,b,c , Cristina Veres i,j , Aurore Surun k , François Doz k,l , Damien Llanas a,b,c , Giao Vu-Bezin a,b,c , Carole Rubino a,b,c , Florent de Vathaire a,b,c , Véronique Letort d , Rodrigue Setcheou Allodji
doi : 10.1016/j.radonc.2023.109479
Volume 180, March 2023, 109479
Valvular Heart Disease (VHD) is a known complication of childhood cancer after radiotherapy treatment. However, the dose-volume-effect relationships have not been fully explored.
Impact of interstitial lung abnormality on survival after adjuvant durvalumab with chemoradiotherapy for locally advanced non-small cell lung cancer
Tairo Kashihara a,⇑, Yuko Nakayama a , Kae Okuma a , Ayaka Takahashi a , Tomoya Kaneda a , Mika Katagiri a , Hiroki Nakayama a , Yuko Kubo c , Kimiteru Ito c , Satoshi Nakamura a , Kana Takahashi a , Koji Inaba a , Naoya Murakami a , Tetsuo Saito d , Hiroyuki Okamoto a , Jun Itami a , Masahiko Kusumoto c , Yuichiro Ohe b , Hiroshi Igaki
doi : 10.1016/j.radonc.2022.109454
Volume 180, March 2023, 109454
Concurrent chemoradiotherapy (CCRT) has been the standard of care for patients with locally advanced non-small cell lung cancer (LA-NSCLC).
Early outcomes of ultra-hypofractionated preoperative radiation therapy for soft tissue sarcoma followed by immediate surgical resection
Zachary S. Mayo a , Shireen Parsai b , Wafa Asha a , Mina Dinh a , Nathan Mesko c , Lukas Nystrom c , Chirag S. Shah a , Jacob G. Scott a , Shauna R. Campbell
doi : 10.1016/j.radonc.2022.109439
Volume 180, March 2023, 109439
There is increasing interest in shorter courses of radiation therapy (RT) in the management of soft tissue sarcoma (STS). We report our institutional experience for patients undergoing ultra-hypofractionated preoperative RT followed by immediate resection.
Survival prediction for stage I-IIIA non-small cell lung cancer using deep learning
Sunyi Zheng a,b,c,⇑, Jiapan Guo a,d , Johannes A. Langendijk a , Stefan Both a , Raymond N.J. Veldhuis e , Matthijs Oudkerk f , Peter M.A. van Ooijen a , Robin Wijsman a , Nanna M. Sijtsema
doi : 10.1016/j.radonc.2023.109483
Volume 180, March 2023, 109483
The aim of this study was to develop and evaluate a prediction model for 2-year overall survival (OS) in stage I-IIIA non-small cell lung cancer (NSCLC) patients who received definitive radiotherapy by considering clinical variables and image features from pre-treatment CT-scans.
Visualization of tumor hypoxia and re-oxygenation after stereotactic body radiation therapy in early peripheral lung cancer: A prospective study
Masahiro Inada a,⇑, Yasumasa Nishimura a , Kohei Hanaoka b , Kiyoshi Nakamatsu a , Hiroshi Doi a , Takuya Uehara a , Mikihito Komanishi b , Kazunari Ishii c , Hayato Kaida c , Makoto Hosono
doi : 10.1016/j.radonc.2023.109491
Volume 180, March 2023, 109491
In this study, fluoromisonidazole positron emission tomography (F-MISO PET/CT) was used to evaluate tumor hypoxia and re-oxygenation in patients with lung tumors treated with stereotactic body radiation therapy (SBRT).
Survival benefit of radiotherapy following narrow-margin hepatectomy in patients with hepatocellular carcinoma: A propensity score-matched analysis based on phase II study
Liuhua Long a,b,1 , Bo Chen b,1 , Hongzhi Wang a,1 , Yuting Zhao a,1 , Fan Wu c , Liming Wang c , Weiqi Rong c , Jianxiong Wu c , Yexiong Li b,⇑, Weihu Wang
doi : 10.1016/j.radonc.2022.109462
Volume 180, March 2023, 109462
We evaluated the postoperative radiotherapy (PORT) effects on hepatocellular carcinoma (HCC) prognosis and recurrence in patients who underwent narrow-margin (<1.0Â cm) hepatectomy (NH).
Outcomes following brachytherapy boost for intermediate- and high-risk prostate cancer: A retrospective bicenter study by the SFRO brachytherapy group
Kanta Ka a , Renaud Schiappa b , Mario Terlizzi a , Frederic Mallet c , Etienne Martin d , Marie-Eve Chand b , Nicolas Demogeot e , Didier Peiffert e , Pascal Pommier f , Magali Quivrin d , Manon Kissel g , Corentin Pasquier h , Jonathan Khalifa h , Alberto Bossi a , Jean-Michel Hannoun-Levi b , Pierre Blanchard
doi : 10.1016/j.radonc.2022.109460
Volume 180, March 2023, 109460
Radiotherapy dose escalation improves biochemical control in intermediate- or high-risk prostate cancer. Brachytherapy boost was shown to further improve biochemical control compared to radiotherapy alone in three randomized trials. The SFRO brachytherapy group sought to evaluate the efficacy and toxicity of BT-boost for intermediate and high-risk prostate cancer in real life, and to determine prognostic factors for efficacy and toxicity.
Recurrence characteristics after focal salvage HDR brachytherapy in prostate cancer
Marnix J.A. Rasing a,⇑, Max Peters a , Marieke van Son b , Marinus A. Moerland a , Wietse Eppinga a , Sandrine M.G. van de Pol a , Juus Noteboom a , Jan Lagendijk a , Jochem R.N. van der Voort van Zyp
doi : 10.1016/j.radonc.2023.109495
Volume 180, March 2023, 109495
Radiorecurrent prostate cancer is often confined to the prostate, predominantly near the index lesion. The purpose of this study was to look at recurrence characteristics in patients treated with focal salvage high dose-rate (HDR) brachytherapy.
Interobserver variation in clinical target volume (CTV) delineation for stereotactic radiotherapy to non-spinal bone metastases in prostate cancer: CT, MRI and PET/CT fusion
Ewan Richard Chapman a,c,⇑, Luke Nicholls d,e , Yae-Eun Suh b , Vincent Khoo b,c , Daniel Levine b , Derfel ap Dafydd b , Nicholas Van As
doi : 10.1016/j.radonc.2022.109461
Volume 180, March 2023, 109461
The use of SBRT for the treatment of oligometastatic prostate cancer is increasing rapidly. While consensus guidelines are available for non-spinal bone metastases practice continues to vary widely. The aim of this study is to look at inter-observer variability in the contouring of prostate cancer non-spinal bone metastases with different imaging modalities.
Evaluation of therapeutic radiographer contouring for magnetic resonance image guided online adaptive prostate radiotherapy
Gillian Adair Smith a,⇑, Alex Dunlop c , Sophie E. Alexander b , Helen Barnes a , Francis Casey c , Joan Chick c , Ranga Gunapala d , Trina Herbert a , Rebekah Lawes a , Sarah A. Mason c , Adam Mitchell c , Jonathan Mohajer c , Julia Murray b , Simeon Nill c , Priyanka Patel b , Angela Pathmanathan b , Kobika Sritharan b , Nora Sundahl b , Alison C. Tree b , Rosalyne Westley b , Bethany Williams a , Helen A. McNair
doi : 10.1016/j.radonc.2022.109457
Volume 180, March 2023, 109457
The implementation of MRI-guided online adaptive radiotherapy has facilitated the extension of therapeutic radiographers’ roles to include contouring, thus releasing the clinician from attending daily treatment. Following undergoing a specifically designed training programme, an online interobserver variability study was performed.
The risk of valvular heart disease in the French Childhood Cancer Survivors’ Study: Contribution of dose-volume histogram parameters
Stefania Chounta a,b,c,d , Sarah Lemler d , Nadia Haddy a,b,c , Brice Fresneau e , Imene Mansouri a,b,c,f,g , Mahmoud Bentriou d , Charlotte Demoor-Goldschmidt a,b,c,h , Ibrahima Diallo i,j , Vincent Souchard a,b,c , Thi-Duyen Do a,b,c , Cristina Veres i,j , Aurore Surun k , François Doz k,l , Damien Llanas a,b,c , Giao Vu-Bezin a,b,c , Carole Rubino a,b,c , Florent de Vathaire a,b,c , Véronique Letort d , Rodrigue Setcheou Allodji
doi : 10.1016/j.radonc.2023.109479
Volume 180, March 2023, 109479
Valvular Heart Disease (VHD) is a known complication of childhood cancer after radiotherapy treatment. However, the dose-volume-effect relationships have not been fully explored.
Early outcomes of ultra-hypofractionated preoperative radiation therapy for soft tissue sarcoma followed by immediate surgical resection
Zachary S. Mayo a , Shireen Parsai b , Wafa Asha a , Mina Dinh a , Nathan Mesko c , Lukas Nystrom c , Chirag S. Shah a , Jacob G. Scott a , Shauna R. Campbell
doi : 10.1016/j.radonc.2022.109439
Volume 180, March 2023, 109439
There is increasing interest in shorter courses of radiation therapy (RT) in the management of soft tissue sarcoma (STS). We report our institutional experience for patients undergoing ultra-hypofractionated preoperative RT followed by immediate resection.
