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Issue Highlights page
doi : 10.1016/S0360-3016(23)00112-8
Volume 115, Issue 5, 1 April 2023, Pages A14-A16
Catalyzing the Next Generation: Interventions To Increase Medical Student Interest in Radiation Oncology
Paris-Ann Ingledew, MD, MHPE,* Nafisha Lalani, MD,y Megan Daly, MD,z and Shauna R. Campbell, DO
doi : 10.1016/j.ijrobp.2022.11.025
Volume 115, Issue 5, 1 April 2023, Pages 1017-1025
Management After an Initial Nononcologic Approach to an HPV+ Head and Neck Cancer
Andrew Tam, MD, and Arya Amini, MD
doi : 10.1016/j.ijrobp.2022.07.1834
Volume 115, Issue 5, 1 April 2023, Page 1026
Radiation Alone After Surgery: Avoiding Trimodality Therapy
Sewit Teckie, MD, MBASalah Almokadem, DO
doi : 10.1016/j.ijrobp.2022.08.066
Volume 115, Issue 5, 1 April 2023, Page 1027
T1N1M0Â +Â p16 Squamous Cell Cancer of Base of Tongue With 3.6-cm Node and <1 mm of ENE
Jonathan J. Beitler, MD, MBA, FASTRO, FARS Neilayan Sen, MD
doi : 10.1016/j.ijrobp.2022.08.002
Volume 115, Issue 5, 1 April 2023, Pages 1027-1028
Take the Road Less Treated
Eric G. Nesbit, MD Laila A. Gharzai, MD, LLM
doi : 10.1016/j.ijrobp.2022.12.040
Volume 115, Issue 5, 1 April 2023, Pages 1028-1029
Just Radiate
Virginia Diavolitsis, MD
doi : 10.1016/j.ijrobp.2023.02.001
Volume 115, Issue 5, 1 April 2023, Page 1029
Development of a United States Radiation Oncology Curricular Framework: A Stakeholder Delphi Consensus
Elizabeth B. Jeans, MEd, MD,* Jeffrey V. Brower, MD, PhD,y Jay W. Burmeister, PhD,z Curtiland Deville, Jr, MD,x Emma Fields, MD,â•‘ Brian D. Kavanagh, MD, MPH,{ John H. Suh, MD, # Ara Tekian, PhD, MHPE,** Neha Vapiwala, MD,yy Elaine M. Zeman, PhD,zz and Daniel W. Golden, MD, MHPE
doi : 10.1016/j.ijrobp.2022.12.009
Volume 115, Issue 5, 1 April 2023, Pages 1030-1040
Radiation Oncologists and Therapeutic Radiopharmaceuticals: Will History Repeat Itself?
Paul E. Wallner, DO,*,y and Michael L. Steinberg, MD
doi : 10.1016/j.ijrobp.2022.11.043
Volume 115, Issue 5, 1 April 2023, Pages 1041-1043
Radiation Oncology and Radiopharmaceuticals: Making Our Own History While Learning From the Past
John M. Buatti, MD,* Ronald D. Ennis, MD,y Ana P. Kiess, MD, PhD,z and Jeff M. Michalski, MD
doi : 10.1016/j.ijrobp.2022.12.024
Volume 115, Issue 5, 1 April 2023, Pages 1044-1046
Assessing Interobserver Variability in the Delineation of Structures in Radiation Oncology: A Systematic Review
Leslie Guzene, MD,* Arnaud Beddok, MD, MSc,y,z Christophe Nioche, PhD,z Romain Modzelewski, PhD,x Cedric Loiseau, PhD,â•‘,{ Julia Salleron, PhD,{ and Juliette Thariat, MD, PhDâ•‘,#, **
doi : 10.1016/j.ijrobp.2022.11.021
Volume 115, Issue 5, 1 April 2023, Pages 1047-1060
An Updated Analysis of the Survival Endpoints of ASCENDE-RT
Justin Oh, MD,* ,y Scott Tyldesley, MD,*,y Howard Pai, MD,z Michael McKenzie, MD,*,y Ross Halperin, MD,x Graeme Duncan, MD,* ,y Gerard Morton, MB,â•‘ Mira Keyes, MD,* ,y Jeremy Hamm, MSc,{ and W. James Morris, MD*
doi : 10.1016/j.ijrobp.2022.11.005
Volume 115, Issue 5, 1 April 2023, Pages 1061-1070
Androgen Suppression Combined With Elective Nodal and Dose Escalated Radiation Therapy: Brachytherapy as Dose Escalation for Localized Prostate Cancer
Thomas M. Pisansky, MD
doi : 10.1016/j.ijrobp.2022.12.007
Volume 115, Issue 5, 1 April 2023, Pages 1071-1073
Long-Term Results of a Phase 3 Randomized Prospective Trial of Erectile Tissue-Sparing Intensity-Modulated Radiation Therapy for Men With Clinically Localized Prostate Cancer
Eddie Zhang, MD,* Karen J. Ruth, MS,y Mark K. Buyyounouski, MD, FASTRO,z Robert A. Price, Jr., PhD, FASTRO,* Robert G. Uzzo, MD, MBA,x Mark L. Sobczak, MD,* Alan Pollack, MD, PhD,â•‘ J. Karen Wong, MD, MEng,* David Y.T. Chen, MD,x Mark A. Hallman, MD, PhD,* Richard E. Greenberg, MD,x Deborah Watkins-Bruner, PhD,{ Tahseen Al-Saleem, MD, # and Eric M. Horwitz, MD, FABS, FASTRO*
doi : 10.1016/j.ijrobp.2022.12.008
Volume 115, Issue 5, 1 April 2023, Pages 1074-1084
Late Toxicity of Moderately Hypofractionated Intensity-Modulated Proton Therapy Treating the Prostate and Pelvic Lymph Nodes for High-Risk Prostate Cancer
Richard Choo, MD,* David W. Hillman, MS,y Cecilia Mitchell, BSc,y Thomas Daniels, MD,z Carlos Vargas, MD,x Jean Claude Rwigema, MD,x Kimberly Corbin, MD,* Sameer Keole, MD,x Sujay Vora, MD,x Kenneth Merrell, MD,* Bradley Stish, MD,* Thomas Pisansky, MD,* Brian J. Davis, MD, PhD,* Adam Amundson, BA,* and William Wong, MD
doi : 10.1016/j.ijrobp.2022.11.027
Volume 115, Issue 5, 1 April 2023, Pages 1085-1094
WNT Pathway Mutations in Metachronous Oligometastatic Castration-Sensitive Prostate Cancer
Philip Sutera, MD,* Matthew P. Deek, MD,y Kim Van der Eecken, MD,z,x Amol C. Shetty, PhD,â•‘,{ Jin Hee Chang, BS,{ Theresa Hodges, PhD,â•‘,{ Yang Song, PhD,â•‘,{ Sofie Verbeke, MD, PhD,x Jo Van Dorpe, MD, PhD,x Valerie Fonteyne, MD, PhD,** Bram De Laere, PhD,z,yy Mark Mishra, MD,{ Zaker Rana, MD,{ Jason Molitoris, MD, PhD,{ Matthew Ferris, MD,{ Ashley Ross, MD,zz Edward Schaeffer, MD, PhD,zz Nicholas Roberts, PhD, VetMB,xx Daniel Y. Song, MD,*,â•‘â•‘,{{ Theodore DeWeese, MD,*,â•‘â•‘,{{ Kenneth J. Pienta, MD,â•‘â•‘,{{ Emmanuel S. Antonarakis, MD, ## Piet Ost, MD, PhD,z, *** and Phuoc T. Tran, MD, PhD
doi : 10.1016/j.ijrobp.2022.12.006
Volume 115, Issue 5, 1 April 2023, Pages 1095-1101
Preservation of Neurocognition after Proton Beam Radiation Therapy for Intracranial Tumors: First Results from REGI-MA-002015
Birgit Flechl, MD, PhD, Lisa Konrath, MA, BSc, Carola L€utgendorf-Caucig, MD, MPH, Milana Achtaewa, MD, Eugen B. Hug, MD, and Petra Georg, MD, PhD
doi : 10.1016/j.ijrobp.2022.09.081
Volume 115, Issue 5, 1 April 2023, Pages 1102-1114
Modulation of Radiation Biomarkers in a Randomized Phase II Study of 131I-MIBG With or Without Radiation Sensitizers for Relapsed or Refractory Neuroblastoma
CLINICAL INVESTIGATION Modulation of Radiation Biomarkers in a Randomized Phase II Study of 131 I-MIBG With or Without Radiation Sensitizers for Relapsed or Refractory Neuroblastoma Kevin Campbell, MD,* Susan Groshen, PhD,y Angela C. Evans, MS,z,x Stephen Wilson, PhD,z Aimy Sebastian, PhD,z Gabriela G. Loots, PhD,z Araz Marachelian, MD,â•‘ Myriam Armant, PhD,* Sharmistha Pal, PhD,{ Daphne A. Haas-Kogan, MD,{ Julie R. Park, MD, # Meaghan Granger, MD,** Katherine K. Matthay, MD,yy Matthew A. Coleman, PhD,z,x and Steven G. DuBois, MD, MS
doi : 10.1016/j.ijrobp.2022.11.045
Volume 115, Issue 5, 1 April 2023, Pages 1115-1128
High-Dose Versus Standard-Dose Intensity-Modulated Radiotherapy With Concurrent Paclitaxel Plus Carboplatin for Patients With Thoracic Esophageal Squamous Cell Carcinoma: A Randomized, Multicenter, Open-Label, Phase 3 Superiority Trial
Jing You, MD,* Shuchai Zhu, MD,y Jiancheng Li, MD,z Jie Li, MD,x Junyue Shen, MD,* Yidian Zhao, MD,â•‘ Xiaomin Li, MD,{ Lin Jia, MD, # Qingshan Li, MD,** Jun Yang, MD,yy Yiqun Wu, PhD,zz Wenbin Shen, MD,y Haishan Wu, MD,z Xueqin Wu, MD,x Xiaomin Wang, MD,â•‘ Yaqiong Ren, MD,{ Jun He, MD, # Pingping Lin, MD,** Guangying Zhu, MD,xx and Anhui Shi, MD*
doi : 10.1016/j.ijrobp.2022.11.006
Volume 115, Issue 5, 1 April 2023, Pages 1129-1137
Left Anterior Descending Coronary Artery Radiation Dose Association With All-Cause Mortality in NRG Oncology Trial RTOG 0617
Elizabeth McKenzie, PhD,* Samuel Zhang, MD,* Roja Zakariaee, PhD,* Christian V. Guthier, PhD,y Behrooz Hakimian, MD,* Amin Mirhadi, MD,* Mitchell Kamrava, MD,* Sukhmani K. Padda, MD,z John H. Lewis, PhD,* Andriana Nikolova, MD, PhD,x Raymond H. Mak, MD,y and Katelyn M. Atkins, MD, PhD
doi : 10.1016/j.ijrobp.2022.11.033
Volume 115, Issue 5, 1 April 2023, Pages 1138-1143
Four-Dimensional Computed Tomography Ventilation Image-Guided Lung Functional Avoidance Radiation Therapy: A Single-Arm Prospective Pilot Clinical Trial
Tokihiro Yamamoto, PhD,* Sven Kabus, PhD,y Matthieu Bal, PhD,z Paul J. Keall, PhD,x Angel Moran, MD,* Cari Wright, BS,* Stanley H. Benedict, PhD,* Devin Holland, AAS,â•‘ Nichole Mahaffey, PhD,â•‘ Lihong Qi, PhD,{ and Megan E. Daly, MD*
doi : 10.1016/j.ijrobp.2022.11.026
Volume 115, Issue 5, 1 April 2023, Pages 1144-1154
International Validation of the EORTC QLQ-ANL27, a Field Study to Test the Anal Cancer-Specific Health-Related Quality-of-Life Questionnaire
Samantha C. Sodergren, PhD,* Colin D. Johnson,* Alexandra Gilbert,y Anne-Sophie Darlington,* Kim Cocks,z Marianne G. Guren,x,â•‘ Eleonor Rivin del Campo,{ Christine Brannan,# Peter Christensen,** William Chu,yy Hans Chung,yy Kristopher Dennis,zz,xx Isacco Desideri,â•‘â•‘ Duncan C. Gilbert,{{ Rob Glynne-Jones, # Michael Jefford, ##, *** Mia Johansson,yyy,zzz Anders Johnsson,xxx Therese Juul,** Dimitrios Kardamakis,â•‘â•‘â•‘ Julia Lai-Kwon, ## Vicky McFarlane,{{{ Isalia M.C. Miguel, ### Karen Nugent,{{{ Femke Peters,**** Rachel P. Riechelmann,yyyy Nazim S. Turhal,zzzz Shun Wong,yy and Vassilios Vassiliou,xxxx on behalf of the Euro- pean Organisation for Research and Treatment of Cancer Quality of Life Group
doi : 10.1016/j.ijrobp.2022.11.002
Volume 115, Issue 5, 1 April 2023, Pages 1155-1164
One-Year Treatment-Related Side Effects and Quality of Life After Chemoradiotherapy in Squamous Cell Carcinoma of the Anus
Anna Cecilie Lefevre, MD,* Eva Serup-Hansen, MD, PhD,y Katrine Smedegaard Storm, MD,y Karen Lycke Wind, MD,* Camilla Kronborg, MD, PhD,z,x and Karen-Lise Garm Spindler, MD, PhD, DMSc*
doi : 10.1016/j.ijrobp.2022.09.071
Volume 115, Issue 5, 1 April 2023, Pages 1165-1177
Patient-Reported Outcome Measures in Anal Carcinoma: Essential, But Are We Magnifying Patient Voice With the Best Megaphone?
Jennifer A. Dorth, MD,* and Christopher J. Anker, MD
doi : 10.1016/j.ijrobp.2022.12.026
Volume 115, Issue 5, 1 April 2023, Pages 1178-1180
Patient-Reported Symptoms of Late Toxicity in Patients With Breast Cancer Treated With Hypofractionated Radiation Therapy and the Association With Quality of Life
M.C.T. Batenburg,* D.R. Mink van der Molen,* F. van der Leij,* A. Doeksen,y T. van Dalen,z E.J.P. Schoenmaeckers,x R.M. Bijlsma,â•‘ A.J. Witkamp,{ M. Ernst, # M.F. Sier,y, ** W. Maarse,yy H.J.G.D. van den Bongard,zz and H.M. Verkooijen,xx on behalf of the UMBRELLA study team
doi : 10.1016/j.ijrobp.2022.11.008
Volume 115, Issue 5, 1 April 2023, Pages 1181-1191
Evidence for Persistent Radiation-Related Injury to the Immune System in Patients With Local Breast Cancer
Janhavi Athale, MD,* Kristen Broderick, MD,y Xiaojun Wu, MD, PhD,z and Stuart Grossman, MD
doi : 10.1016/j.ijrobp.2022.11.028
Volume 115, Issue 5, 1 April 2023, Pages 1192-1196
Image Guidance Volume-Modulated Arc Radiation Therapy Concurrently With Nab-Paclitaxel Plus Cisplatin for Patients With Locally Advanced Cervical Cancer: A Single-Arm Dose Escalation Trial
Ping Jiang, MD,* Xiuwen Deng, MD,* Ang Qu, MD,* Weijuan Jiang, MD,* Fuxin Guo, MD,* Qin Han, MD,y Hongyan Guo, MD,y and Junjie Wang, PhD, MD
doi : 10.1016/j.ijrobp.2022.11.011
Volume 115, Issue 5, 1 April 2023, Pages 1197-1204
Exploring the Cost of Radiation Therapy Delivery for Locally Advanced Cervical Cancer in a Public and a Private Center in Latin America Using Time-Driven Activity-Based Costing
Benjamin Li, MD, MBA,*,y Emily Hirata, PhD,* Juan Manuel Trejo, MD,z Bertha Garcia, MSc,x Betty Chang, BA,y,â•‘ Sameeksha Malhotra, BA,y,{ Matthew Ning, MD, MPH, # and Gustavo J. Sarria, MD
doi : 10.1016/j.ijrobp.2022.11.046
Volume 115, Issue 5, 1 April 2023, Pages 1205-1216
Outcomes Stratification of Head and Neck Cancer Using Pre- and Post-treatment DNA Methylation From Peripheral Blood
David C. Qian, MD, PhD,* Bryan C. Ulrich, MD,y Gang Peng, PhD,z Hongyu Zhao, PhD,z Karen N. Conneely, PhD,x Andrew H. Miller, MD,â•‘ Deborah W. Bruner, PhD, RN,{ Ronald C. Eldridge, PhD, MPH,{ Evanthia C. Wommack, BS,â•‘ Kristin A. Higgins, MD,* Dong M. Shin, MD, # Nabil F. Saba, MD, # Alicia K. Smith, PhD,** Barbara Burtness, MD,yy Henry S. Park, MD, MPH,xx William A. Stokes, MD,* Jonathan J. Beitler, MD, MBA,* and Canhua Xiao, PhD, RN
doi : 10.1016/j.ijrobp.2022.11.009
Volume 115, Issue 5, 1 April 2023, Pages 1217-1228
Docosahexaenoic Acid Attenuates Radiation-Induced Myocardial Fibrosis by Inhibiting the p38/ET-1 Pathway in Cardiomyocytes
Yuchen Liu, MD,*,y Pengxiang Chen, PhD,* ,y Tianyu Liu, MD,* Bo Cheng, PhD,* Changhua Sun, PhD,z Huixian Xin, MD,* Zhihua Wen, PhD,* and Yufeng Cheng, PhD
doi : 10.1016/j.ijrobp.2022.11.007
Volume 115, Issue 5, 1 April 2023, Pages 1229-1243
Deficiency of Carbamoyl Phosphate Synthetase 1 Engenders Radioresistance in Hepatocellular Carcinoma via Deubiquitinating c-Myc
Sisi Zhang, MM,* ,# Yue Hu, MD,*,# Zilong Wu, MM,*,# Xiaoshu Zhou, MD,* Tong Wu, MD,y Pindong Li, MD,y Qiuyu Lian, PhD,z Shuangbing Xu, MD,* Jin Gu, PhD,z Lei Chen, PhD,y Gang Wu, MD,* Tao Zhang, MD,* Jing Tang, MD,* and Jun Xue, MD*
doi : 10.1016/j.ijrobp.2022.11.022
Volume 115, Issue 5, 1 April 2023, Pages 1244-1256
Experimental Validation of a Real-Time Adaptive 4D-Optimized Particle Radiotherapy Approach to Treat Irregularly Moving Tumors
Timo Steinsberger, MSc,*,y Marco Donetti, MSc,z Michelle Lis, PhD,*,x,k Lennart Volz, PhD,* Moritz Wolf, PhD,* Marco Durante, PhD,* ,y and Christian Graeff, PhD*
doi : 10.1016/j.ijrobp.2022.11.034
Volume 115, Issue 5, 1 April 2023, Pages 1257-1268
Investigation of In-Field and Out-of-Field Radiation Quality With Microdosimetry and Its Impact on Relative Biological Effectiveness in Proton Therapy
Marta Missiaggia, PhD,*,y,z Giorgio Cartechini,*,y Francesco Tommasino, PhD,* ,y Emanuele Scifoni, PhD,y and Chiara La Tessa, PhD
doi : 10.1016/j.ijrobp.2022.11.037
Volume 115, Issue 5, 1 April 2023, Pages 1269-1282
Automated Robust Planning for IMPT in Oropharyngeal Cancer Patients Using Machine Learning
Ilse G. van Bruggen, MSc,* Merle Huiskes, MSc,* Suzanne P.M. de Vette, MSc,* Mats Holmstr€om, MSc,y Johannes A. Langendijk, MD, PhD,* Stefan Both, PhD,* Roel G.J. Kierkels, PhD,z and Erik W. Korevaar, PhD*
doi : 10.1016/j.ijrobp.2022.12.004
Volume 115, Issue 5, 1 April 2023, Pages 1283-1290
Dosiomics Risk Model for Predicting Radiation Induced Temporal Lobe Injury and Guiding Individual Intensity-Modulated Radiation Therapy
Shan-Shan Yang, MD,*,y Pu-Yun OuYang, MD,* Jian-Gui Guo, MD,z Jia-Jun Cai, MS,x Jun Zhang, MD,* Qing-He Peng, MD,* Yun He, MD,â•‘ Bao-Yu Zhang, MD,* Zhi-Qiao Liu, MD,* Xue-Feng Hu, MD,z Yan-Feng Chen, MD,{ Chun-Yan Chen, MD,* and Fang-Yun Xie, MD
doi : 10.1016/j.ijrobp.2022.11.036
Volume 115, Issue 5, 1 April 2023, Pages 1291-1300
Predicted Inferior Outcomes for Lung SBRT With Treatment Planning Systems That Fail Independent Phantom-Based Audits
Matthew D. Greer, MD, a,c Brandon Koger, PhD,b Mallory Glenn, PhD, a John Kang, MD, PhD,a Ramesh Rengan, MD, PhD, a Jing Zeng, MD, a and Eric Ford, PhD
doi : 10.1016/j.ijrobp.2022.12.003
Volume 115, Issue 5, 1 April 2023, Pages 1301-1308
