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Table of Contents
doi : 10.1016/S1529-9430(21)01022-6
Volume 22, Issue 2, February 2022, Pages A3-A6
Biomechanical changes in the lumbar spine following spaceflight and factors associated with postspaceflight disc herniation
Jeannie F. Bailey, PhD a, *, Priya Nyayapati, BS a , Gabriel T.A. Johnsona , Lucas Dziesinski, BS a , Aaron W. Scheffler, PhD b , Rebecca Crawford, PhD c , Richard Scheuring, DO d , Conor W. O’Neill, MD a , Douglas Chang, MDe , Alan R. Hargens, PhD e , Jeffrey C. Lotz, PhD
doi : 10.1016/j.spinee.2021.07.021
Volume 22, Issue 2, February 2022, Pages 197-206
For chronic low back pain, the causal mechanisms between pathological features from imaging and patient symptoms are unclear. For instance, disc herniations can often be present without symptoms.
What does the patient with back pain want? A comparison of patient preferences and physician assumptions
Matthew Smuck, MDa, *, Kevin Barrette, MD b , Agnes Martinez-Ith a,b,c , Geoffrey Sultana, MDc , Patricia Zheng, MD
doi : 10.1016/j.spinee.2021.09.007
Volume 22, Issue 2, February 2022, Pages 207-213
Low back pain can be difficult to diagnose, leaving patients frustrated and confused after medical visits.
Relationship between systemic inflammation and recovery over 12 months after an acute episode of low back pain
David M. Klyne, PhD, MSc, DPhty, BAppSc a , Mary F. Barbe, PhD, BSc b , Paul W. Hodges, PhD, MedDr, DSc, Bphty
doi : 10.1016/j.spinee.2021.09.006
Volume 22, Issue 2, February 2022, Pages 214-225
Individual characteristics can influence outcomes after injury. Our previous work in individuals with early-acute low back pain (LBP) identified subgroups (clusters) with specific biopsychosocial features that recovered poorly or well by 6 months.
The effectiveness of intradiscal biologic treatments for discogenic low back pain: a systematic review
Byron J. Schneider, MDa, *, Christine Hunt, DOb , Aaron Conger, DO c , Wenchun Qu, MD, PhD d , Timothy P. Maus, MD e , Yakov Vorobeychik, MD, PhDf , Jianguo Cheng, MD, PhD g , Belinda Duszynski, BSh , Zachary L. McCormick, MD
doi : 10.1016/j.spinee.2021.07.015
Volume 22, Issue 2, February 2022, Pages 226-237
There are limited treatments for discogenic low back pain. Intradiscal injections of biologic agents such as platelet-rich plasma (PRP) or stem cells (SC) are theorized to have regenerative properties and have gained increasing interest as a possible treatment, but the evidence supporting their use in clinical practice is not yet well-defined.
Transfusion guidelines in adult spine surgery: a systematic review and critical summary of currently available evidence
Umaru Barrie, BS a, *, Carl A. Youssef, MDa , Mark N. Pernik, BA a , Emmanuel Adeyemo, BA a , Mahmoud Elguindy, BA a , Zachary D. Johnson, MDa , Tarek Y. El Ahmadieh, MD a , Omar S. Akbik, MD a,c , Carlos A. Bagley, MD, MBA a,b,c , Salah G. Aoun, MDa,
doi : 10.1016/j.spinee.2021.07.018
Volume 22, Issue 2, February 2022, Pages 238-248
Red blood cell transfusion can be associated with complications in medical and surgical patients. Acute anemia in ambulatory patients undergoing surgery can also impede wound healing and independent self-care
The association between atlantoaxial instability and anomalies of vertebral artery and axis
Chan Woong Byun, MD a , Dong-Ho Lee, MD, PhD b, *, Sehan Park, MD c , Choon Sung Lee, MD, PhDb , Chang Ju Hwang, MD, PhDb , Jae Hwan Cho, MD, PhD
doi : 10.1016/j.spinee.2021.08.014
Volume 22, Issue 2, February 2022, Pages 249-255
A screw-rod system is the most widely used technique for atlantoaxial instability (AAI). However, neglecting anomalies of the vertebral artery and axis could lead to fatal complications. Whether or not the presence of AAI is associated with a more complicated anatomy for instrumentation is unclear.
Prospective comparison of dysphagia following anterior cervical discectomy and fusion (ACDF) with and without rhBMP-2#
J. Taylor Bellamy, MD a,x, Eric Dilbone, MDa,x, Adam Schell, MD a , Ajay Premkumar, MDa , Benjamin Geddes, MD a , Steven Leckie, MDb , Bradley Moatz, MDb , Byron Stephens, MD b , Neeta V. Shenvi, MS c , John G. Heller, MD
doi : 10.1016/j.spinee.2021.09.001
Volume 22, Issue 2, February 2022, Pages 256-264
Previous studies have called into question the safety of using rhBMP-2 in anterior cervical fusion due to the possibility of airway compromise and dysphagia. A retrospective chart review identified a significant increase in the severity of dysphagia after II-level ACDF with rhBMP-2 compared to patients who did not receive rhBMP-2. To date, this topic has not been studied prospectively.
Costs associated with potentially unnecessary postoperative healthcare encounters after lumbar spine surgery
Neda F. Gilmartin, MD, Leah Y. Carreon, MD, MSc*, Jeffrey L. Gum, MD, John R. Dimar II, MD, Morgan E. Brown, MS, Steven D. Glassman, MD
doi : 10.1016/j.spinee.2021.08.009
Volume 22, Issue 2, February 2022, Pages 265-271
Excessive use of postoperative imaging after lumbar surgery has been documented, becoming a target for cutting costs. This must be balanced with the patient's need for information and allay their postoperative concerns.
Natural language processing for prediction of readmission in posterior lumbar fusion patients: which free-text notes have the most utility?
Aditya V. Karhade, MD, MBA a,b , Ophelie Lavoie-Gagne, MDa , Nicole Agaronnik, BA a , Hamid Ghaednia, PhD a , Austin K. Collins, BSa , David Shin, BS a , Joseph H. Schwab, MD, MS
doi : 10.1016/j.spinee.2021.08.002
Volume 22, Issue 2, February 2022, Pages 272-277
The increasing volume of free-text notes available in electronic health records has created an opportunity for natural language processing (NLP) algorithms to mine this unstructured data in order to detect and predict adverse outcomes. Given the volume and diversity of documentation available in spine surgery, it remains unclear which types of documentation offer the greatest value for prediction of adverse outcomes.
A cross-sectional analysis of 284 complications for lumbar disc replacements from medical device reports maintained by the United States Food and Drug Administration
Petros Koutsogiannis, DO a, *, Safdar Khan, MDb , Frank Phillips, MD c , Sheeraz Qureshi, MD, MBAd , Thomas J. Dowling, MD a , Junho Song, BSa , Sohrab Virk, MD, MBA
doi : 10.1016/j.spinee.2021.08.001
Volume 22, Issue 2, February 2022, Pages 278-285
Lumbar disc replacement (LDR) is a motion sparing procedure for degenerative disc disease. When compared to lumbar fusion, this procedure may reduce complications, reoperations, operative time, and length of stay.
Frailty is an important predictor of 30-day morbidity in patients treated for lumbar spondylolisthesis using a posterior surgical approach
Vivien Chan, MDa,b , Christopher D. Witiw, MD, MSc, FRCSC b , Jamie R.F. Wilson, MD, MSc, FRCSC b,c,d , Jefferson R. Wilson, MD, PhD, FRCSC b , Peter Coyte, PhD e , Michael G. Fehlings, MD, PhD, FRCSC
doi : 10.1016/j.spinee.2021.08.008
Volume 22, Issue 2, February 2022, Pages 286-295
Traditionally, a nonoperative approach has been favored for elderly patients with lumbar spondylolisthesis due to a perceived higher risk of morbidity with surgery. However, most studies have used an arbitrary age cut-off to define “elderly” and this research has yielded conflicting results.
Femoral nerve neuromonitoring for lateral lumbar interbody fusion surgery
Justin W. Silverstein, DHSc a,h,r, *, Jon Block, DC b , Michael L. Smith, MDc,h , David A. Bomback, MDd,p , Scott Sanderson, MD e,p , Justin Paul, MDf,p , Hieu Ball, MDg , Jason A. Ellis, MD h , Matthew Goldstein, MDi,q , David L. Kramer, MDd,p , Grigoriy Arutyunyan, MDc,h , Joshua Marcus, MDe,p , Sara Mermelstein, BSj , Paul Slosar, MD k , Noel Goldthwaite, MD k , Sun Ik Lee, MDl , James Reynolds, MD k , Margaret Riordan, MD m , Nick Pirnia, MDm , Sandeep Kunwar, MDn , Gaurav Abbi, MDk , Bruce Bizzini, CNIM b , Sarita Gupta, MDb , Dorothy Porter, BSa , Laurence E. Mermelstein, MD
doi : 10.1016/j.spinee.2021.07.017
Volume 22, Issue 2, February 2022, Pages 296-304
The transpsoas lateral lumbar interbody fusion (LLIF) technique is an effective alternative to traditional anterior and posterior approaches to the lumbar spine; however, nerve injuries are the most reported postoperative complication. Commonly used strategies to avoid nerve injury (eg, limiting retraction duration) have not been effective in detecting or preventing femoral nerve injuries.
Single distraction-rod constructs in severe early-onset scoliosis: Indications and outcomes
Scott J. Luhmann, MDa, *, David L. Skaggs, MDb , Joshua Pahys, MD c , Amer Samdani, MDc , Ron El-Hawary, MD
doi : 10.1016/j.spinee.2021.09.004
Volume 22, Issue 2, February 2022, Pages 305-312
Since the study of Thompson, et al in 2005, use of dual-growing rod constructs have become the gold standard for operative treatment in early-onset scoliosis. However, use of dual-growing rod constructs may not be possible, due to patient size and the type, location and severity of the spinal deformity.
Paraspinal muscle fatty degeneration as a predictor of progressive vertebral collapse in osteoporotic vertebral compression fractures
Ikchan Jeon, MD, Sang Woo Kim, MD, Dongwoo Yu, MD*
doi : 10.1016/j.spinee.2021.07.020
Volume 22, Issue 2, February 2022, Pages 313-320
Most osteoporotic vertebral compression fractures (OVCFs) are treated conservatively; however, in some patients, progressive vertebral body collapse leads to spinal deformity and cord compression. These complications are strongly associated with impaired performance activities of daily living and a poor quality of life.
Development of a clinical prediction rule for patients with cervical spinal cord injury who have difficulty in obtaining independent living
Tomonari Hori, BSa , Takeshi Imura, PhD b,c, *, Ryo Tanaka, PhD
doi : 10.1016/j.spinee.2021.08.010
Volume 22, Issue 2, February 2022, Pages 321-328
A simple and easy to use clinical prediction rule (CPR) to detect patients with a cervical spinal cord injury (SCI) who would have difficulty in obtaining independent living status is vital for providing the optimal rehabilitation and education in both care recipients and caregivers.
Development of a machine learning algorithm for predicting in-hospital and 1-year mortality after traumatic spinal cord injury
Nader Fallah, PhD a,b , Vanessa K. Noonan, PT, PhDa, *, Zeina Waheed, MSc a , Carly S. Rivers, PhD a , Tova Plashkes, MScPT a , Manekta Bedi, MSc a , Mahyar Etminan, PharmD, MSc c , Nancy P. Thorogood, PhDa , Tamir Ailon, MD, MPHd , Elaine Chan, MPT, BSc a , Nicolas Dea, MD, MSc d , Charles Fisher, MD, MHSC d , Raphaele Charest-Morin, MDd , Scott Paquette, MD, MEdd , SoEyun Park, BSc a , John T. Street, MD, PhD d , Brian K. Kwon, MD, PhDd , Marcel F. Dvorak, MD, MBA
doi : 10.1016/j.spinee.2021.08.003
Volume 22, Issue 2, February 2022, Pages 329-336
Current prognostic tools such as the Injury Severity Score (ISS) that predict mortality following trauma do not adequately consider the unique characteristics of traumatic spinal cord injury (tSCI).
FAM20C plays a critical role in the development of mouse vertebra
Yanyu Huang, DDS, PhDa,b,c,1 , Hongfei Chen, DDS, PhDa,b,c,1 , Hua Zhang, MD, PhD a , Yongbo Lu, MD, PhDa , Chunlin Qin, DDS, PhD
doi : 10.1016/j.spinee.2021.07.022
Volume 22, Issue 2, February 2022, Pages 337-348
Family with sequence similarity 20-member C (FAM20C) is a protein kinase that is responsible for the phosphorylation of many secretory proteins; however, its roles in spine or vertebra development have not be studied.
Corrigendum to ‘Vertebral fractures and neurological injury associated with increased recreational vehicle use’ [The Spine Journal 21/9S (2021) S215]
Sachin Gupta, MDa , Thriaksh Rajan, BAb , Sarthak Mohanty, BS b , Comron Saifi, MD
doi : 10.1016/j.spinee.2021.10.005
Volume 22, Issue 2, February 2022, Page 349
Corrigendum to ‘Incidence of lumbar vertebral fractures based on etiology throughout the United States from 2010 to 2018′ [The Spine Journal 21/9S (2021) S133-S134]
Jonathan Wakim, BA a , Thriaksh Rajan, BA b , Alex Beschloss, BA a , Ahmed A. Albayar, MD c , Ali K. Ozturk, MDc , Vincent Arlet, MDd , Comron Saifi, MD
doi : 10.1016/j.spinee.2021.10.004
Volume 22, Issue 2, February 2022, Page 350
Corrigendum to ‘Epidemiological trends associated with football-related spine injuries’ [The Spine Journal 21/9S (2021) S133]
Sarthak Mohanty, BSa , Thriaksh Rajan, BAa , Thaddeus Woodard, BSa , Sachin Gupta, MD a , David Falk, MDa , Alex Beschloss, BA a , David Casper, MD b , Comron Saifi, MD
doi : 10.1016/j.spinee.2021.10.003
Volume 22, Issue 2, February 2022, Page 351
