Transplantation

Antibody-mediated rejection (AMR) is an important cause of graft loss and continues to present a formidable obstacle to successful transplantation. Unresolved problems continue to be the absence of effective strategies to ablate the donor-specific antibody (DSA) response as well as to attenuate the antibody-mediated graft tissue injury. While the properties of DSA that cause greater graft tissue injury and the characteristic microvascular pathology of the graft injury are well documented, the mechanisms underlying the injury mediated by the antibodies remains unclear. Recent transcriptome interrogation of kidney and heart biopsies procured during ongoing AMR has indicated the expression of genes associated with natural killer (NK) cell activation that is absent during T cell–mediated rejection. The expression of NK cell transcripts during AMR correlates with the presence of CD56+ cells in the microcirculation inflammation observed during AMR. Several mouse models have recently demonstrated the role of NK cells in antibody-mediated chronic vasculopathy in heart allografts and the requirement for NK cell activation during acute AMR of kidney allografts. In the latter model, NK cell activation within kidney allografts is regulated by the activation of myeloid cells producing myeloperoxidase. Overall, the studies to date indicate that AMR constitutes a complex series of DSA-induced interactions with components of the innate immune response. The innate immune participants and their expressed effector functions resulting in the rejection are beginning to be identified. The identification of these components should uncover novel targets that can be used to attenuate acute graft tissue injury in the presence of DSA.

خرید پکیج و مشاهده آنلاین مقاله

The Clinical Conundrum of Cannabis: Current Practices and Recommendations for Transplant Clinicians: An Opinion of the Immunology/Transplantation PRN of the American College of Clinical Pharmacy

Melaragno, Jennifer I. PharmD1; Bowman, Lyndsey J. PharmD2; Park, Jeong M. MS, PharmD3; Lourenco, Laura M. PharmD4; Doligalski, Christina T. PharmD, CPP5; Brady, Bethany L. PharmD6; Descourouez, Jillian L. PharmD7; Chandran, Mary M. PharmD8; Nickels, Mark W. MD9; Page, Robert L. II PharmD, MSHP10

doi : 10.1097/TP.0000000000003309

Transplantation: February 2021 - Volume 105 - Issue 2 - p 291-299

Cannabis, or marijuana, comprises many compounds with varying effects. It has become a treatment option for chronic diseases and debilitating symptoms, and evidence suggests that it has immunomodulatory and antiinflammatory properties. Transplant centers are more frequently facing issues about cannabis, as indications and legalization expand. As of February 2020, 33 states and the District of Columbia have legalized medical cannabis, and 14 have legalized recreational cannabis. Moreover, 8 states have passed legislation prohibiting the denial of transplant listing solely based on cannabis use. Studies demonstrate the potential for significant pharmacokinetic and pharmacodynamic interactions between cannabis and immunosuppression. Additionally, safety concerns include increased risk of myocardial infarction, ischemic stroke, tachyarrhythmias, malignancy, neurocognitive deficits, psychosis, other neuropsychiatric disorders, cannabis use disorder, respiratory symptoms, and infection. A recent retrospective database study found a negative association between documented cannabis use disorder and graft survival, but little additional evidence exists evaluating this relationship. In the absence of robust clinical data, transplant centers need a clear, reasoned, and systematic approach to cannabis. The results of our national survey, unfortunately, found little consensus among institutions. As both recreational and medicinal cannabis become more ubiquitous nationwide, transplant centers will need to develop comprehensive policies to address its use.

خرید پکیج و مشاهده آنلاین مقاله

The Role of SLAs in Xenotransplantation

Ladowski, Joseph M. PhD1; Hara, Hidetaka MD, PhD1; Cooper, David K.C. MD, PhD1

doi : 10.1097/TP.0000000000003303

Transplantation: February 2021 - Volume 105 - Issue 2 - p 300-307

Advances in genetic engineering, particularly CRISPR/Cas9, have resulted in the development of a triple glycan-knockout (TKO) pig. There is minimal human antipig antibody binding to TKO pig cells. The TKO background has decreased antibody binding to a sufficiently low level that any additional xenoantigens expressed on the cells can now be more easily detected. One of these xenoantigens is the swine major histocompatibility complex, termed swine leukocyte antigens (SLA). SLA are the homolog to HLAs, a protein complex expressed on human tissue capable of stimulating the development of new antibodies in allotransplantation. These antibodies can result in graft failure through hyperacute, acute, or chronic rejection. Our knowledge of SLA, particularly in the last 5 years, has grown considerably. The presence, cause, and methods to detect anti-SLA antibodies will need to be carefully considered for the first clinical trial of xenotransplantation. The focus of this review is to summarize the role of SLA in xenotransplantation and consider whether it will prove to be a major barrier. Techniques are now available to mutate target SLA amino acids to ensure that cross-reactive anti-HLA antibodies no longer bind to SLA on the cells of the organ-source pigs. While deletion of SLA expression is possible, it would render the pig at risk for infectious complications. The ideal organ-source pig for HLA highly sensitized recipients may therefore be 1 with site-specific mutations to eliminate cross-reactive binding.

خرید پکیج و مشاهده آنلاین مقاله

An Addition of U0126 Protecting Heart Grafts From Prolonged Cold Ischemia-Reperfusion Injury in Heart Transplantation: A New Preservation Strategy

Zheng, Hao PhD1,2; Su, Yale MSc, MD1,3; Zhu, Cuilin MD, PhD1,3; Quan, Douglas MD, PhD4,5; Skaro, Anton I. MD, PhD4,5; McAlister, Vivian MD4,5; Lacefield, James C. PhD6,7,8,9; Jiang, Jifu MD5; Xue, Peng MD, PhD1; Wang, Yefu PhD2; Zheng, Xiufen PhD1,4,5,8,9

doi : 10.1097/TP.0000000000003402

Transplantation: February 2021 - Volume 105 - Issue 2 - p 308-317

Ischemia-reperfusion injury (IRI) is the major cause of primary graft dysfunction in organ transplantation. The mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) signaling pathway plays a crucial role in cell physiological and pathological processes including IRI. This study aims to investigate whether inhibition of ERK signaling with U0126 can prevent prolonged cold IRI in heart transplantation.

خرید پکیج و مشاهده آنلاین مقاله

Anti-pig IgE and IgA Antibodies in Naive Primates and Nonhuman Primates With Pig Xenografts

Li, Qi MD1,2; Iwase, Hayato MD, PhD1; Yamamoto, Takayuki MD, PhD1; Nguyen, Huy Quoc BS, MS1; Ayares, David PhD3; Wang, Yi MD, PhD4,5; Cooper, David K.C. MD, PhD, FRCS1; Hara, Hidetaka MD, PhD1

doi : 10.1097/TP.0000000000003408

Transplantation: February 2021 - Volume 105 - Issue 2 - p 318-327

Natural preformed anti-pig IgM/IgG antibodies in primates play an important role in xenograft rejection. As it is not clear how IgE and IgA engage in the immune system in xenotransplantation, we investigated natural preformed and elicited anti-pig IgE/IgA in naive primates and after xenotransplantation in nonhuman primates.

خرید پکیج و مشاهده آنلاین مقاله

Impact of Donor Age on the Outcome of Living-donor Liver Transplantation: Special Consideration to the Feasibility of Using Elderly Donors

Kadohisa, Masashi MD1; Inomata, Yukihiro PhD2; Uto, Keiichi PhD1; Hayashida, Shintaro MD1; Ohya, Yuki PhD1; Yamamoto, Hidekazu PhD1; Sugawara, Yasuhiko PhD1; Hibi, Taizo PhD1

doi : 10.1097/TP.0000000000003246

Transplantation: February 2021 - Volume 105 - Issue 2 - p 328-337

The use of elderly donors (?60 y) in living-donor liver transplantation (LDLT) remains controversial. In this study, we aimed to determine the safety of surgery for elderly donors and the impact of donor age on LDLT outcomes.

خرید پکیج و مشاهده آنلاین مقاله

Risk Factors and Impact of Perioperative Prophylaxis on the Risk of Extended-spectrum ?-Lactamase–producing Enterobacteriaceae–related Infection Among Carriers Following Liver Transplantation

Logre, Elsa MD1; Bert, Frédéric MD2; Khoy-Ear, Linda MD1; Janny, Sylvie MD1; Giabicani, Mikhaël MD1; Grigoresco, Bénédicte MD1; Toussaint, Amélie MD1; Dondero, Fédérica MD3; Dokmak, Safi MD, PhD3; Roux, Olivier MD4; Francoz, Claire MD, PhD4,5; Soubrane, Olivier MD, PhD3,5,6; Durand, François MD, PhD4,5,6; Paugam-Burtz, Catherine MD, PhD1,5,6; Weiss, Emmanuel MD, PhD1,5,6

doi : 10.1097/TP.0000000000003231

Transplantation: February 2021 - Volume 105 - Issue 2 - p 338-345

Extended-spectrum ?-lactamase–producing Enterobacteriaceae (ESBL-E) carriage is frequent among liver transplant (LT) recipients, thereby fostering a large empirical carbapenem prescription. However, ESBL-E infections occur in only 10%–25% of critically ill patients with rectal colonization. Our aim was to identify risk factors for post-LT ESBL-E infection in colonized patients. The effect of perioperative antimicrobial prophylaxis (AP) was also analyzed in patients with prophylaxis lasting <48 hours and without proven intraoperative infection.

خرید پکیج و مشاهده آنلاین مقاله

Long-term Outcomes and Survival in Moderate-severe Portopulmonary Hypertension After Liver Transplant

Sadd, Corey J. MD1; Osman, Fauzia MPH1; Li, Zhanhai PhD1; Chybowski, Amy MSN1; Decker, Catherine PharmD2; Henderson, Bruce RN1; Goss, Kara N. MD1; Hammel, Laura L. MD3; Runo, James R. MD1

doi : 10.1097/TP.0000000000003248

Transplantation: February 2021 - Volume 105 - Issue 2 - p 346-353

خرید پکیج و مشاهده آنلاین مقاله

Inducible Left Ventricular Outflow Tract Obstruction in Patients Undergoing Liver Transplantation: Prevalence, Predictors, and Association With Cardiovascular Events

Cailes, Benjamin MBBS (Hons)1; Koshy, Anoop N. MBBS (Hons), FRACP1; Gow, Paul MBBS, MD, FRACP2; Weinberg, Laurence MBBS, MD, FANZCA3; Srivastava, Piyush MBBS, FRACP1; Testro, Adam MBBS, FRACP, PhD2; Peverelle, Matthew MD2; Ko, Jefferson MD1; Salehi, Hamid MBBS, FRACP1; Jones, Elizabeth F. MBBS, FRACP, PhD1; Calafiore, Paul MBBS, FRACP1; Farouque, Omar MBBS (Hons), FRACP, FACC, PhD1

doi : 10.1097/TP.0000000000003245

Transplantation: February 2021 - Volume 105 - Issue 2 - p 354-362

Inducible left ventricular outflow tract obstruction (LVOTO) is often encountered in liver transplantation (LT) candidates during cardiac workup. While the impact of LVOTO on adverse cardiovascular hemodynamics is well reported, it is unclear whether it predisposes to perioperative cardiovascular complications.

خرید پکیج و مشاهده آنلاین مقاله

The Impact of Portal Vein Thrombosis on Liver Transplant Outcomes: Does Grade or Flow Rate Matter?

Rizzari, Michael D. MD1; Safwan, Mohamed MBBS1; Sobolic, Michael MD1; Kitajima, Toshihiro MD1; Collins, Kelly MD1; Yoshida, Atsushi MD1; Abouljoud, Marwan MD1; Nagai, Shunji MD1

doi : 10.1097/TP.0000000000003235

Transplantation: February 2021 - Volume 105 - Issue 2 - p 363-371

Portal vein thrombosis (PVT) makes the technical aspect of liver transplantation challenging and also affects outcomes. Our aim was to study impact of PVT grade and postreperfusion portal flow on posttransplant outcomes.

خرید پکیج و مشاهده آنلاین مقاله

Factors Associated With Residual Kidney Function and Proteinuria After Living Kidney Donation in the United States

Augustine, Joshua J. MD1; Arrigain, Susana MA2; Mandelbrot, Didier A. MD3; Schold, Jesse D. PhD2; Poggio, Emilio D. MD1

doi : 10.1097/TP.0000000000003210

Transplantation: February 2021 - Volume 105 - Issue 2 - p 372-381

Living kidney donors are carefully screened, but despite overall good health, long-term donor outcomes have been shown to vary by predonation demographics. Since 2013, the United Network for Organ Sharing has mandated 2-year postdonation follow-up with measurements of kidney function and proteinuria.

خرید پکیج و مشاهده آنلاین مقاله

Chest X-ray Sizing for Lung Transplants Reflects Pulmonary Diagnosis and Body Composition and Is Associated With Primary Graft Dysfunction Risk

Li, David BSc1; Weinkauf, Justin MD1; Hirji, Alim MD, MSc1; Nagendran, Jayan MD, PhD2; Kapasi, Ali MD1; Lien, Dale MD1; Halloran, Kieran MD, MSc1

doi : 10.1097/TP.0000000000003238

Transplantation: February 2021 - Volume 105 - Issue 2 - p 382-389

Donor-recipient oversizing based on predicted total lung capacity (pTLC) is associated with a reduced risk of primary graft dysfunction (PGD) following lung transplant but the effect varies with the recipient’s diagnosis. Chest x-ray (CXR) measurements to estimate actual total lung capacity (TLC) could account for disease-related lung volume changes, but their role in size matching is unknown.

خرید پکیج و مشاهده آنلاین مقاله

The Impact of Inadequate (“AX”) Transbronchial Biopsies on Post–lung Transplant CLAD or Death

Levy, Liran MD1,2; Huszti, Ella PhD3; Pal, Prodipto MD, PhD4; Tikkanen, Jussi MD, PhD1; Ghany, Rasheed MSc1; Keshavjee, Shaf MD1; Martinu, Tereza MD1; Singer, Lianne G. MD1

doi : 10.1097/TP.0000000000003213

Transplantation: February 2021 - Volume 105 - Issue 2 - p 390-395

Procuring a good quality transbronchial-biopsy sample is essential for diagnosing acute cellular rejection after lung transplantation (LT). Insufficient transbronchial-biopsy samples are graded “AX.” We hypothesized that AX samples may be associated with a higher risk for chronic lung allograft dysfunction (CLAD) or death/retransplant, through a potential anatomic or physiologic underlying pulmonary process or because of undiagnosed acute cellular rejection episodes.

خرید پکیج و مشاهده آنلاین مقاله

External Validation of the DynPG for Kidney Transplant Recipients

Lenain, Rémi MSc1; Dantan, Etienne PhD2; Giral, Magali PhD3,4; Foucher, Yohann PhD2,5; Asar, ?zgür PhD6; Naesens, Maarten PhD7,8; Hazzan, Marc PhD1; Fournier, Marie-Cécile PhD2

doi : 10.1097/TP.0000000000003209

Transplantation: February 2021 - Volume 105 - Issue 2 - p 396-403

In kidney transplantation, dynamic prediction of patient and kidney graft survival (DynPG) may help to promote therapeutic alliance by delivering personalized evidence-based information about long-term graft survival for kidney transplant recipients. The objective of the current study is to externally validate the DynPG.

خرید پکیج و مشاهده آنلاین مقاله

Disparity in Accessibility to and Prognosis of Kidney Transplantation According to Economic Inequality in South Korea: A Widening Gap After Expansion of Insurance Coverage

Park, Sehoon MD1,2; Park, Gi Chan AS3; Park, Jina MSc3; Kim, Ji Eun MD4,5; Yu, Mi-yeon MD6; Kim, Kwangsoo PhD3; Park, Minsu PhD7; Kim, Yong Chul MD, PhD4; Kim, Dong Ki MD, PhD4,8,9; Joo, Kwon Wook MD, PhD4,8,9; Kim, Yon Su MD, PhD1,4,8,9; Lee, Hajeong MD, PhD4

doi : 10.1097/TP.0000000000003256

Transplantation: February 2021 - Volume 105 - Issue 2 - p 404-412

Nationwide studies on the effects of wealth inequality on kidney transplantation are rare, particularly in a country with an expanded National Health Insurance Service and in Asian countries.

خرید پکیج و مشاهده آنلاین مقاله

Cardiac Mortality in Kidney Transplant Patients: A Population-based Cohort Study 1988–2013 in Australia and New Zealand

Wyld, Melanie L.R. MBBS, MBA, MPH, PhD1,3; De La Mata, Nicole L. BSc, MBiostats, PhD4; Masson, Philip MBChB, PhD5; O’Lone, Emma MBChB4,6; Kelly, Patrick J. PhD4; Webster, Angela C. MBBS, MM, PhD1,4

doi : 10.1097/TP.0000000000003224

Transplantation: February 2021 - Volume 105 - Issue 2 - p 413-422

Transplant recipients experience excess cardiac mortality. We compared circulatory death rates in Australian and New Zealand kidney transplant recipients to the general population and identified risk factors for circulatory death in kidney transplant recipients.

خرید پکیج و مشاهده آنلاین مقاله

Immunologic Clearance of a BK Virus-associated Metastatic Renal Allograft Carcinoma

Meier, Raphael P.H. MD, PhD1,2; Muller, Yannick D. MD, PhD2,3; Dietrich, Pierre-Yves MD4; Tille, Jean-Christophe MD, PhD5; Nikolaev, Sergey PhD6; Sartori, Ambra MSc6; Labidi-Galy, Intidhar MD, PhD4; Ernandez, Thomas MD7; Kaur, Amandeep MSc8; Hirsch, Hans H. MD8; McKee, Thomas A. MD5; Toso, Christian MD, PhD1; Villard, Jean MD, PhD3,7; Berney, Thierry MD, MSc1

doi : 10.1097/TP.0000000000003193

Transplantation: February 2021 - Volume 105 - Issue 2 - p 423-429

Metastatic carcinoma of a renal allograft is a rare but life threatening event with a difficult clinical management. Recent reports suggested a potential role of BK polyomavirus (BKPyV) in the development of urologic tract malignancies in kidney transplant recipients.

خرید پکیج و مشاهده آنلاین مقاله

Short- and Long-term Outcomes of Kidney Transplants From Very Small (?15 kg) Pediatric Donors With Acute Kidney Injury

Troppmann, Christoph MD1; Santhanakrishnan, Chandrasekar MD1; Fananapazir, Ghaneh MD2; Sageshima, Junichiro MD1; Troppmann, Kathrin M. MD1; Perez, Richard V. MD1

doi : 10.1097/TP.0000000000003230

Transplantation: February 2021 - Volume 105 - Issue 2 - p 430-435

Kidneys from small deceased pediatric donors with acute kidney injury (AKI) are commonly discarded owing to transplant centers’ concerns regarding potentially inferior short- and long-term posttransplant outcomes.

خرید پکیج و مشاهده آنلاین مقاله

Center-level Variation in HLA-incompatible Living Donor Kidney Transplantation Outcomes

Jackson, Kyle R. MD, PhD1; Long, Jane BA1; Motter, Jennifer MHS1; Bowring, Mary G. MPH1; Chen, Jennifer BS1; Waldram, Madeleine M. BA1; Orandi, Babak J. MD, PhD2; Montgomery, Robert A. MD3; Stegall, Mark D. MD4; Jordan, Stanley C. MD5; Benedetti, Enrico MD6; Dunn, Ty B. MD7; Ratner, Lloyd E. MD8; Kapur, Sandip MD9; Pelletier, Ronald P. MD10; Roberts, John P. MD11; Melcher, Marc L. MD, PhD12; Singh, Pooja MD13; Sudan, Debra L. MD14; Posner, Marc P. MD15; El-Amm, Jose M. MD16; Shapiro, Ron MD17; Cooper, Matthew MD18; Verbesey, Jennifer E. MD18; Lipkowitz, George S. MD19; Rees, Michael A. MD, PhD20; Marsh, Christopher L. MD21; Sankari, Bashir R. MD22; Gerber, David A. MD23; Wellen, Jason MD24; Bozorgzadeh, Adel MD25; Gaber, A. Osama MD26; Heher, Eliot MD27; Weng, Francis L. MD28; Djamali, Arjang MD29; Helderman, J. Harold MD30; Concepcion, Beatrice P. MD30; Brayman, Kenneth L. MD31; Oberholzer, Jose MD31; Kozlowski, Tomasz MD32; Covarrubias, Karina BS33; Desai, Niraj MD1; Massie, Allan B. PhD, MHS1; Segev, Dorry L. MD, PhD1,34,35,*; Garonzik-Wang, Jacqueline MD, PhD1,*

doi : 10.1097/TP.0000000000003254

Transplantation: February 2021 - Volume 105 - Issue 2 - p 436-442

Desensitization protocols for HLA-incompatible living donor kidney transplantation (ILDKT) vary across centers. The impact of these, as well as other practice variations, on ILDKT outcomes remains unknown.

خرید پکیج و مشاهده آنلاین مقاله

Renal Function Improvement Following ANG-3777 Treatment in Patients at High Risk for Delayed Graft Function After Kidney Transplantation

Bromberg, Jonathan S. MD1; Weir, Matthew R. MD1; Gaber, A. Osama MD2; Yamin, Michael A. PhD3; Goldberg, Itzhak D. MD3; Mayne, Tracy J. PhD3; Cal, Weizhong PhD3; Cooper, Matthew MD4

doi : 10.1097/TP.0000000000003255

Transplantation: February 2021 - Volume 105 - Issue 2 - p 443-450

Patients (20%–50%) undergoing renal transplantation experience acute kidney injury resulting in delayed graft function. ANG-3777 is an hepatocyte growth factor mimetic that binds to the c-MET receptor. In animal models, ANG-3777 decreases apoptosis, increases proliferation, and promotes organ repair and function.

خرید پکیج و مشاهده آنلاین مقاله

CD38 Antibody Daratumumab for the Treatment of Chronic Active Antibody-mediated Kidney Allograft Rejection

Doberer, Konstantin MD1; Kl?ger, Johannes MD2; Gualdoni, Guido A. MD, PhD1; Mayer, Katharina A. MD1,3; Eskandary, Farsad MD, PhD1; Farkash, Evan A. MD4; Agis, Hermine MD5; Reiter, Thomas MD1; Reindl-Schwaighofer, Roman MD1; Wahrmann, Markus PhD1; Cohen, Gerald PhD1; Haslacher, Helmuth MD6; Bond, Gregor MD, PhD1; Simonitsch-Klupp, Ingrid MD2; Halloran, Philip F. MD, PhD7; B?hmig, Georg A. MD1

doi : 10.1097/TP.0000000000003247

Transplantation: February 2021 - Volume 105 - Issue 2 - p 451-457

Late antibody-mediated rejection (AMR) is a major cause of transplant failure. Potential therapeutic targets are plasma cells and natural killer (NK) cells, both expressing high levels of CD38.

خرید پکیج و مشاهده آنلاین مقاله

Comment on “A Worldwide Survey of Live Liver Donor Selection Policies at 24 Centers With a Combined Experience of 19 009 Adult Living Donor Liver Transplants”

Akbulut, Sami MD1; Sahin, Tevfik Tolga MD1; Yilmaz, Sezai MD1

doi : 10.1097/TP.0000000000003465

Transplantation: February 2021 - Volume 105 - Issue 2 - p e18

خرید پکیج و مشاهده آنلاین مقاله

Reply to Comment: A Worldwide Survey of Live Liver Donor Selection Policies at 24 Centers With a Combined Experience of 19 009 Adult Living Donor Liver Transplants

Soin, Arvinder Singh MBBS, MS, FRCS1; Jagat Chaudhary, Rohan MS1; Pahari, Hirak MS1; Pomfret, Elizabeth MD, PhD2

doi : 10.1097/TP.0000000000003466

Transplantation: February 2021 - Volume 105 - Issue 2 - p e19

خرید پکیج و مشاهده آنلاین مقاله

Living Donor Liver Transplantation During the COVID-19 Pandemic: A Serendipitous Silver Lining!

Menon, Jagadeesh DM1; Hakeem, Abdul R. FRCS1; Rammohan, Ashwin FRCS1; Sundaramoorthy, Subha MD1; Kanagavelu, Rathnavel G. FRCA1; Reddy, Mettu S. FRCS1; Rela, Mohamed FRCS1

doi : 10.1097/TP.0000000000003574

Transplantation: February 2021 - Volume 105 - Issue 2 - p e20-e21

خرید پکیج و مشاهده آنلاین مقاله

Mild Course of SARS-CoV-2 Infection in a Liver Transplant Recipient Undergoing Plasma Exchange and Defibrotide for Acute Graft Rejection

Merli, Marco MD1; Alteri, Claudia PhD2,3; Colagrossi, Luna PhD2,3; Perricone, Giovanni MD4; Chiappetta, Stefania MD1; Travi, Giovanna MD1; Campisi, Daniela MD2; Pugliano, Maria Teresa MD5; Vecchi, Marta MD1; Orcese, Carloandrea MD1; Rossini, Silvano MD5; De Carlis, Luciano MD6,7; Vismara, Chiara MD2; Belli, Luca MD4; Perno, Carlo Federico MD2,3; Puoti, Massimo MD1

doi : 10.1097/TP.0000000000003592

Transplantation: February 2021 - Volume 105 - Issue 2 - p e22-e24

خرید پکیج و مشاهده آنلاین مقاله

Treatment of Degenerative Disc Disease With Allogeneic Mesenchymal Stem Cells: Long-term Follow-up Results

Noriega, David C. MD, PhD1; Ardura, Francisco MD, PhD1; Hern?ndez-Ramajo, Rubén MD, PhD1; Mart?n-Ferrero, Miguel ?ngel MD, PhD1; S?nchez-Lite, Israel MD2; Toribio, Borja MD2; Alberca, Mercedes PhD3; Garc?a, Ver?nica PhD3; Moraleda, José M. MD, PhD4; Gonz?lez-Vallinas, Margarita PhD5; S?nchez, Ana MD, PhD5; Garc?a-Sancho, Javier MD, PhD5

doi : 10.1097/TP.0000000000003471

Transplantation: February 2021 - Volume 105 - Issue 2 - p e25-e27

خرید پکیج و مشاهده آنلاین مقاله

Machine Perfusion—Leaving Its Mark on Liver Transplantation

Richards, James A. PhD1,2,3; Gaurav, Rohit MS1,2,3; Upponi, Sara S. MPhil4; Watson, Christopher J.E. MD1,2,3; Butler, Andrew J. MChir1,2,3

doi : 10.1097/TP.0000000000003462

Transplantation: February 2021 - Volume 105 - Issue 2 - p e28-e29

خرید پکیج و مشاهده آنلاین مقاله