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Serine slows diabetic neuropathy in mice
Shimona StarlingÂÂ
doi : 10.1038/s41574-023-00811-w
Volume 19 Issue 4, April 2023
A role for circulating levels of uridine in regulating hunger and food intake
Claire GreenhillÂÂ
Aster pathway maintains hepatic cholesterol homeostasis
Olivia TysoeÂÂ
Sulfonylurea secondary failure mechanism identified
Olivia TysoeÂÂ
The effect of long-term statin use on diabetic nephropathy
Claire GreenhillÂÂ
A pipeline for identification and validation of brain targets for weight loss
Anthony Tsang & Clemence BlouetÂ
EDC exposure in 3D genome memory in transgenerational obesity
Xudong Zhang & Qi ChenÂ
Applying the WHO global targets for diabetes mellitus
Alice Y. Y. Cheng, MarÃÂlia Brito Gomes, Sanjay Kalra, Andre-Pascal Kengne, Chantal Mathieu & Jonathan E. ShawÂ
Beyond the pancreas: contrasting cardiometabolic actions of GIP and GLP1
Rola Hammoud & Daniel J. DruckerÂ
doi : 10.1038/s41574-022-00783-3
Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP1) exhibit incretin activity, meaning that they potentiate glucose-dependent insulin secretion. The emergence of GIP receptor (GIPR)–GLP1 receptor (GLP1R) co-agonists has fostered growing interest in the actions of GIP and GLP1 in metabolically relevant tissues
Sex hormones in SARS-CoV-2 susceptibility: key players or confounders?
Nicola Lott, Caroline E. Gebhard, Susan Bengs, Ahmed Haider, Gabriela M. Kuster, Vera Regitz-Zagrosek & Catherine GebhardÂ
doi : 10.1038/s41574-022-00780-6
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has a clear sex disparity in clinical outcomes. Hence, the interaction between sex hormones, virus entry receptors and immune responses has attracted major interest as a target for the prevention and treatment of SARS-CoV-2 infections.
Towards a better understanding of diabetes mellitus using organoid models
Belin Selcen Beydag-Tasöz, Siham Yennek & Anne Grapin-BottonÂ
doi : 10.1038/s41574-022-00797-x
Our understanding of diabetes mellitus has benefited from a combination of clinical investigations and work in model organisms and cell lines.
