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Addressing Online Extremism—Lessons From Current Threats to Gender-Affirming Care
Rishub K. Das, BA1; Oren Ganor, MD, MSc2; Brian C. Drolet, MD3
doi : 10.1001/jamapediatrics.2022.6157
April 2023, Vol 177, No. 4, Pages 327-441
COVID-19 Vaccines in Young Children—Reassuring Evidence for Parents
Paul A. Offit, MD1
The Healthy, Hunger-Free Kids Act and Children’s Body Mass Index Outcomes
Lauren Fiechtner, MD, MPH1,2; Jennifer Woo Baidal, MD, MPH3; Erika R. Cheng, PhD, MPA4
Short Message Service Reminder Nudge for Parents and Influenza Vaccination Uptake in Children and Adolescents With Special Risk Medical ConditionsThe Flutext-4U Randomized Clinical Trial
Jane Tuckerman, PhD1,2,3; Kelly Harper, BHSc4,5; Thomas R. Sullivan, PhD6,7; Alana R. Cuthbert, PhD6; Jennifer Fereday, PhD4; Jennifer Couper, MD1,4,5; Nicholas Smith, PhD1,4; Andrew Tai, PhD1,4,5; Andrew Kelly, MBBS1,4; Richard Couper, MBChB4; Mark Friswell, MBChB4; Louise Flood, MBBS8; Christopher C. Blyth, PhD9,10,11,12; Margie Danchin, PhD2,3,13; Helen S. Marshall, MD1,4,5
doi : 10.1001/jamapediatrics.2022.6145
Importance Children with chronic medical conditions are at increased risk of severe influenza. Uptake of influenza vaccination in children and adolescents with these identified special risk medical conditions (SRMCs) is suboptimal.
Effect of an Intranasal Corticosteroid on Quality of Life and Local Microbiome in Young Children With Chronic RhinosinusitisA Randomized Clinical Trial
Marta Latek, MSc1; Piotr �acwik, MD, PhD2; Katarzyna Molińska, MSc1; Andrzej Błauż, MSc, PhD3; Jakub Lach, MSc4; Błażej Rychlik, MSc, PhD3; Dominik Strapagiel, MSc, PhD4; Joanna Majak, MD, PhD5; Joanna Molińska, MSc1; Dorota Czech, MD, PhD6; Michał Seweryn, PhD7; Piotr Kuna, MD, PhD1; Cezary Pałczyński, MD, PhD2; Paweł Majak, MD, PhD8
doi : 10.1001/jamapediatrics.2022.6172
Importance Intranasal corticosteroids (INCs) remain the first-line treatment of chronic rhinosinusitis (CRS) in both adults and children, despite the lack of evidence regarding their efficacy in the pediatric population. Similarly, their effect on the sinonasal microbiome has not been well documented.
Effect of Vitamin D Supplementation on Bone Mass in Infants With 25-Hydroxyvitamin D Concentrations Less Than 50 nmol/LA Prespecified Secondary Analysis of a Randomized Clinical Trial
Nathalie Gharibeh, PhD1; Maryam Razaghi, PhD1; Catherine A. Vanstone, RN, MSc1; Olusola F. Sotunde, PhD1; Laura Glenn, RD, MSc1; Kristina Mullahoo, RD, MSc1; Zahra Farahnak, PhD1,2; Ali Khamessan, PhD3; Shu Qin Wei, MD, PhD4; Dayre McNally, MD, PhD5; Frank Rauch, MD6; Glenville Jones, PhD7; Martin Kaufmann, PhD7; Hope A. Weiler, PhD1,8
doi : 10.1001/jamapediatrics.2022.5837
Importance The dose of supplemental vitamin D needed in infants born with serum 25-hydroxyvitamin D (25[OH]D) concentrations less than 50 nmol/L (ie, 20 ng/mL) is unclear.
Global Proportion of Disordered Eating in Children and AdolescentsA Systematic Review and Meta-analysis
José Francisco López-Gil, PhD1,2; Antonio GarcÃa-Hermoso, PhD3; Lee Smith, PhD4; Joseph Firth, PhD5,6; Mike Trott, PhD4,7; Arthur Eumann Mesas, PhD1,8; Estela Jiménez-López, PhD1; Héctor Gutiérrez-Espinoza, PhD9; Pedro J. Tárraga-López, PhD10; Desirée Victoria-Montesinos, PhD11
doi : 10.1001/jamapediatrics.2022.5848
Importance The 5-item Sick, Control, One, Fat, Food (SCOFF) questionnaire is the most widely used screening measure for eating disorders. However, no previous systematic review and meta-analysis determined the proportion of disordered eating among children and adolescents.
Sensitivity and Specificity of the Modified Checklist for Autism in Toddlers (Original and Revised)A Systematic Review and Meta-analysis
Andrea Trubanova Wieckowski, PhD1; Lashae N. Williams, MS1; Juliette Rando, MPH1; Kristen Lyall, ScD1; Diana L. Robins, PhD1
doi : 10.1001/jamapediatrics.2022.5975
Importance The Modified Checklist for Autism in Toddlers (M-CHAT) and the M-CHAT, Revised With Follow-up (M-CHAT-R/F)—henceforth referred to as M-CHAT(-R/F)—are the most commonly used toddler screeners for autism spectrum disorder (ASD). Their use often differs from that in the original validation studies, resulting in a range of estimates of sensitivity and specificity.
Assessment of Efficacy and Safety of mRNA COVID-19 Vaccines in Children Aged 5 to 11 YearsA Systematic Review and Meta-analysis
Atsuyuki Watanabe, MD1; Ryoma Kani2; Masao Iwagami, MD, PhD3,4; Hisato Takagi, MD, PhD5; Jun Yasuhara, MD6; Toshiki Kuno, MD, PhD7
doi : 10.1001/jamapediatrics.2022.6243
Importance Evidence of the efficacy and safety of messenger RNA (mRNA) COVID-19 vaccines in children aged 5 to 11 years has been emerging. Collecting these data will inform clinicians, families, and policy makers.
US Infant Pertussis Incidence Trends Before and After Implementation of the Maternal Tetanus, Diphtheria, and Pertussis Vaccine
Tami H. Skoff, MS1; Li Deng, PhD1; Catherine H. Bozio, PhD1,2; Susan Hariri, PhD1
doi : 10.1001/jamapediatrics.2022.5689
Importance Infants younger than 1 year have the highest burden of pertussis morbidity and mortality. In 2011, the US introduced tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccination during pregnancy to protect infants before vaccinations begin.
Changes in Body Mass Index Among School-Aged Youths Following Implementation of the Healthy, Hunger-Free Kids Act of 2010
Aruna Chandran, MD, MPH1; Mohamad Burjak, MS1; Joshua Petimar, ScD2; Ghassan Hamra, PhD1; Melissa M. Melough, PhD3; Anne L. Dunlop, MD, MPH4; Brittney M. Snyder, PhD5; Augusto A. Litonjua, MD, MPH6; Tina Hartert, MD, MPH7; James Gern, MD8,9; Akram N. Alshawabkeh, PhD10; Judy Aschner, MD11,12; Carlos A. Camargo Jr, MD, DrPH13; Dana Dabelea, MD, PhD14; Cristiane S. Duarte, PhD, MPH15; Assiamira Ferrara, MD, PhD16; Jody M. Ganiban, PhD17; Frank Gilliland, MD, PhD18; Diane R. Gold, MD, MPH19,20; Monique Hedderson, PhD, MPH16; Julie B. Herbstman, PhD21; Christine Hockett, PhD22,23; Margaret R. Karagas, PhD24; Jean M. Kerver, PhD25,26; Kathleen A. Lee-Sarwar, MD19,27; Barry Lester, PhD28; Cindy T. McEvoy, MD29; Zhongzheng Niu, PhD18; Joseph B. Stanford, MD30,31; Rosalind Wright, MD, MPH32; Emily Zimmerman, PhD33; Shohreh Farzan, PhD19; Zhumin Zhang, PhD34; Emily Knapp, PhD1
doi : 10.1001/jamapediatrics.2022.5828
Importance The prevalence of obesity among youths 2 to 19 years of age in the US from 2017 to 2018 was 19.3%; previous studies suggested that school lunch consumption was associated with increased obesity. The Healthy, Hunger-Free Kids Act of 2010 (HHFKA) strengthened nutritional standards of school-based meals.
Myocarditis or Pericarditis Events After BNT162b2 Vaccination in Individuals Aged 12 to 17 Years in Ontario, Canada
Sarah A. Buchan, PhD1,2,3; Sarah Alley, MPH1; Chi Yon Seo, MSc1; Caitlin Johnson, MPH1; Jeffrey C. Kwong, MD1,2,3,4,5; Sharifa Nasreen, PhD2,3; Nisha Thampi, MD1,6; Diane Lu, MD1; Tara M. Harris, MHSc1; Andrew Calzavara, MSc2; Sarah E. Wilson, MD1,2,3
doi : 10.1001/jamapediatrics.2022.6166
Importance The risk of myocarditis or pericarditis after COVID-19 messenger RNA vaccines varies by age and sex, and there is some evidence to suggest increasing risk with shorter intervals between dose 1 and 2 (ie, interdose interval).
Psychometric Properties of Screening Instruments for Social Network Use Disorder in Children and AdolescentsA Systematic Review
Samantha Schlossarek, MSc1; Hannah Schmidt, MSc1,2; Anja Bischof, PhD1; Gallus Bischof, PhD1; Dominique Brandt, MSc1; Stefan Borgwardt, MD1; Dillon T. Browne, PhD3; Dimitri Christakis, MD, MPH4; Pamela Hurst-Della Pietra, DO5; Zsolt Demetrocvics, PhD6,7; Hans-Jürgen Rumpf, PhD1
doi : 10.1001/jamapediatrics.2022.5741
Importance Children and adolescents spend considerable time on the internet, which makes them a highly vulnerable group for the development of problematic usage patterns. A variety of screening methods have already been developed and validated for social network use disorder (SNUD); however, a systematic review of SNUD in younger age groups has not been performed.
What Is Parent-Child Interaction Therapy?
Michelle Curtin, DO1; Lindsay A. Thompson, MD, MS1
Estimated Effectiveness of Postpartum Maternal Messenger RNA COVID-19 Vaccination Against Delta and Omicron SARS-CoV-2 Infection and Hospitalization in Infants Younger Than 6 Months
Sarah C. J. Jorgensen, PharmD, MPH1; Alejandro Hernandez, MSc2; Deshayne B. Fell, PhD3; Peter C. Austin, PhD2; Rohan D’Souza, MD, PhD4; Astrid Guttmann, MDCM, MSc2; Jeffrey C. Kwong, MD, MSc2
Association of Supplemental Nutrition Assistance Program Retailers With Child Food Insecurity During the COVID-19 Pandemic
Qingxiao Li, PhD1; Shuoli Zhao, PhD2; Metin Çakır, PhD3; Zhixiu Yu, PhD4
Disparities in Pediatric Medical and Childcare Disruption Due to COVID-19
Kelsi Batioja, BS1; Covenant Elenwo, MPH1; Micah Hartwell, PhD2
Chronic Food Insecurity in US Families With Children
Noura Insolera, PhD, MA1
Race and the 2022 American Academy of Pediatrics Hyperbilirubinemia Guideline
Alex R. Kemper, MD, MPH, MS1; Thomas B. Newman, MD, MPH2,3; Joseph L. Wright, MD, MPH4,5
Race and the 2022 American Academy of Pediatrics Hyperbilirubinemia Guideline
William Christopher Golden, MD1
Race and the 2022 American Academy of Pediatrics Hyperbilirubinemia Guideline—Reply
Sharon Ostfeld-Johns, MD1; Elena Aragona, MD1; Louis Hart, MD1
Messenger RNA Vaccine in Mother’s Milk
Riccardo Davanzo, MD, PhD1
Messenger RNA Vaccine in Mother’s Milk
Jennifer M. Nelson, MD, MPH1; Katherine E. Fleming-Dutra, MD2; Dana Meaney-Delman, MD, MPH3
Messenger RNA Vaccine in Mother’s Milk—Reply
Nazeeh Hanna, MD1; Christie Clauss, PharmD2; Leonard R. Krilov, MD3
Time to End Community Acquired as an Adjectival Diagnosis for Pneumonia
Miles M. Weinberger, MD1
Time to End Community Acquired as an Adjectival Diagnosis for Pneumonia—Reply
Qinyuan Li, MD1,2,3,4; Yaolong Chen, MD, PhD5,6; Zhengxiu Luo, MD1,2,3,4
