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April 2023 Stroke Highlights.
Sur, Nicole B. MD
doi : 10.1161/STROKEAHA.123.042995
Volume 54(4) pgs. 909-1170,e126-e189 April 2023
Open Data Challenge to Examine the Impact of Social Determinants of Health on Stroke.
Hall, Jennifer L. PhD; Roth, Gregory A. MD
Transcranial Direct-Current Stimulation in Subacute Aphasia: A Randomized Controlled Trial.
Stockbridge, Melissa D. PhD, CCC-SLP; Elm, Jordan PhD; Breining, Bonnie L. PhD; Tippett, Donna C. MPH, MA, CCC-SLP; Sebastian, Rajani PhD, CCC-SLP; Cassarly, Christy PhD; Teklehaimanot, Abeba MS; Spell, Leigh Ann PhD, CCC-SLP; Sheppard, Shannon M. PhD, CCC-SLP; Vitti, Emilia CCC-SLP; Ruch, Kristina CCC-SLP; Goldberg, Emily B. CCC-SLP; Kelly, Catherine CCC-SLP; Keator, Lynsey M. PhD, CCC-SLP; Fridriksson, Julius PhD, CCC-SLP; Hillis, Argye E. MD, MA
doi : 10.1161/STROKEAHA.122.041557
Transcranial direct-current stimulation (tDCS) is a promising adjunct to therapy for chronic aphasia. Methods: This single-center, randomized, double-blind, sham-controlled efficacy trial tested the hypothesis that anodal tDCS augments language therapy in subacute aphasia.
Change in Smoking Behavior and Outcome After Ischemic Stroke: Post-Hoc Analysis of the SPS3 Trial.
Anadani, Mohammad MD; Turan, Tanya N. MD; Yaghi, Shadi MD; Spiotta, Alejandro M. MD; Gory, Benjamin MD PhD; Sharma, Richa MD; Sheth, Kevin N. MD; de Havenon, Adam MD
doi : 10.1161/STROKEAHA.121.038202
Cigarette smoking is a known risk factor for cardiovascular disease, including ischemic stroke. The literature regarding the rate of persistent smoking after acute ischemic stroke and its effect on subsequent cardiovascular events is scarce.
Endovascular Therapy or Medical Management Alone for Isolated Posterior Cerebral Artery Occlusion: A Multicenter Study.
Sabben, Candice MD; Charbonneau, Frederique MD; Delvoye, Francois MD; Strambo, Davide MD; Heldner, Mirjam R. MD; Ong, Elodie MD; Ter Schiphorst, Adrien MD; Henon, Hilde MD; Ben Hassen, Wagih MD; Agasse-Lafont, Thomas MD; Legris, Loic MD; Sibon, Igor MD; Wolff, Valerie MD; Sablot, Denis MD; Elhorany, Mahmoud MD; Preterre, Cecile MD; Nehme, Nour MD; Soize, Sebastien MD;
doi : 10.1161/STROKEAHA.122.042283
Whether endovascular therapy (EVT) added on best medical management (BMM), as compared to BMM alone, is beneficial in acute ischemic stroke with isolated posterior cerebral artery occlusion is unknown.
Prevalence and Therapeutic Implications of Clonal Hematopoiesis of Indeterminate Potential in Young Patients With Stroke.
Mayerhofer, Ernst MD; Strecker, Christoph MD; Becker, Heiko MD; Georgakis, Marios K. MD, PhD; Uddin, Md Mesbah PhD; Hoffmann, Michael M. PhD; Nadarajah, Niroshan MSc; Meggendorfer, Manja PhD; Haferlach, Torsten MD, PhD; Rosand, Jonathan MD, MSc; Natarajan, Pradeep MD, MMSc; Anderson, Christopher D. MD, MMSc; Harloff, Andreas MD ,*; Hoermann, Gregor MD, PhD ,*
doi : 10.1161/STROKEAHA.122.041416
Undetermined stroke etiology hampers optimal secondary prevention in a large proportion of young patients. We explored whether genetic screening for clonal hematopoiesis of indetermined potential (CHIP), a novel risk factor for stroke, could identify patients with myeloid precursor lesions or covert myeloid neoplasm requiring specific treatment.
Early Stroke and Mortality After Percutaneous Left Atrial Appendage Occlusion in Patients With Atrial Fibrillation.
Kogan, Edward V. MD; Sciria, Christopher T. MD; Liu, Christopher F. MD; Wong, S. Chiu MD; Bergman, Geoffrey MD; Ip, James E. MD; Thomas, George MD; Markowitz, Steven M. MD; Lerman, Bruce B. MD; Kim, Luke K. MD; Cheung, Jim W. MD
doi : 10.1161/STROKEAHA.122.041057
Percutaneous endocardial left atrial appendage occlusion (LAAO) is an alternative therapy for stroke prevention in patients with atrial fibrillation who are poor candidates for oral anticoagulants.
Differential Impact of Brain Network Efficiency on Poststroke Motor and Attentional Deficits.
Evangelista, Giorgia G. PhD ,,*; Egger, Philip PhD ,,*; Brugger, Julia PhD; Beanato, Elena MS; Koch, Philipp J. MD; Ceroni, Martino MS; Fleury, Lisa PhD; Cadic-Melchior, Andeol MS; Meyer, Nathalie H. MS; Rodriguez, Diego de Leon PhD; Girard, Gabriel PhD; Leger, Bertrand PhD; Turlan, Jean-Luc MD; Muhl, Andreas MD; Vuadens, Philippe MD; Adolphsen, Jan MD; Jagella, Caroline E. MD; Constantin, Christophe MD; Alvarez, Vincent MD; San Millan, Diego MD; Bonvin, Christophe MD; Morishita, Takuya PhD; Wessel, Maximilian J. MD; Van De Ville, Dimitri PhD; Hummel, Friedhelm C. MD
doi : 10.1161/STROKEAHA.122.040001
Most studies on stroke have been designed to examine one deficit in isolation; yet, survivors often have multiple deficits in different domains. While the mechanisms underlying multiple-domain deficits remain poorly understood, network-theoretical methods may open new avenues of understanding.
Stroke Recurrence and Antiplatelets in Posterior Versus Anterior Circulation Minor Stroke or Transient Ischemic Attack.
Liu, Huihui MD, PhD ,,,*; Jing, Jing MD, PhD ,,*; Wang, Anxin PhD; Xu, Qin PhD; Meng, Xia MD, PhD; Li, Hao PhD; Li, Zixiao MD, PhD; Wang, Yongjun MD
doi : 10.1161/STROKEAHA.122.041738
It is unclear whether infarct location affects stroke recurrence after index ischemic stroke. We aimed to compare the risk of stroke recurrence and the responses to dual antiplatelets with ticagrelor-aspirin versus clopidogrel-aspirin between patients with posterior circulation infarct (PCI) and those with anterior circulation infarct (ACI) after minor stroke or transient ischemic attack.
A Genomic Risk Score Identifies Individuals at High Risk for Intracerebral Hemorrhage.
Myserlis, Evangelos Pavlos MD ,,,,,*; Georgakis, Marios K. MD, PhD ,,,,,*; Demel, Stacie L. DO, PhD ,*; Sekar, Padmini MS; Chung, Jaeyoon PhD; Malik, Rainer PhD; Hyacinth, Hyacinth I. MD, PhD; Comeau, Mary E. MA; Falcone, Guido J. MD, ScD, MPH; Langefeld, Carl D. PhD; Rosand, Jonathan MD, MSc; Woo, Daniel MD ,+; Anderson, Christopher D. MD, MMSc ,,,+
doi : 10.1161/STROKEAHA.122.041701
Intracerebral hemorrhage (ICH) has an estimated heritability of 29%. We developed a genomic risk score for ICH and determined its predictive power in comparison to standard clinical risk factors.
Association Between Hospital-Documented Atrial Fibrillation and Central Retinal Artery Occlusion.
Lusk, Jay B. BSc; Song, Ailin MHS; Unnithan, Shakthi MS; Al-Khalidi, Hussein R. PhD; Delic, Alen MS; de Havenon, Adam MD, MS; Biousse, Valerie MD; Schrag, Matthew MD, PhD; Poli, Sven MD; Piccini, Jonathan P. MD, MHS; Xian, Ying MD, PhD; O'Brien, Emily C. PhD; Mac Grory, Brian MB BCh BAO, MRCP
doi : 10.1161/STROKEAHA.122.042292
Carotid stenosis is thought to be the primary risk factor for central retinal artery occlusion (CRAO); however, it is not known whether atrial fibrillation (AF)-a cardiac arrhythmia that underlies over 25% of cerebral ischemic strokes-predisposes patients to CRAO.
Cost-Effectiveness of Smoking Cessation Interventions in Patients With Ischemic Stroke and Transient Ischemic Attack.
Wechsler, Paul M. MD; Liberman, Ava L. MD; Restifo, Daniel MA; Abramson, Erika L. MD, MSc; Navi, Babak B. MD, MS; Kamel, Hooman MD, MS; Parikh, Neal S. MD, MS
doi : 10.1161/STROKEAHA.122.040356
Smoking cessation rates after stroke and transient ischemic attack are suboptimal, and smoking cessation interventions are underutilized. We performed a cost-effectiveness analysis of smoking cessation interventions in this population.
Trends in Disparities in Advanced Neuroimaging Utilization in Acute Stroke: A Population-Based Study.
Vagal, Achala MD, MS; Sucharew, Heidi PhD; Wang, Lily L. MD, MPH; Kissela, Brett MD, MS; Alwell, Kathleen RN; Haverbusch, Mary RN; Woo, Daniel MD; Ferioli, Simona MD; Mackey, Jason MD; De Los Rios La Rosa, Felipe MD; Mistry, Eva A. MD; Demel, Stacie L. DO, PhD; Coleman, Elisheva MD; Jasne, Adam S. MD; Walsh, Kyle MD; Khatri, Pooja MD, MSc; Slavin, Sabreena MD; Star, Michael MD; Stephens, Cody MD; Kleindorfer, Dawn MD
doi : 10.1161/STROKEAHA.122.040790
Our primary objective was to evaluate if disparities in race, sex, age, and socioeconomic status (SES) exist in utilization of advanced neuroimaging in year 2015 in a population-based study.
Using Epidemiological Data to Inform Clinical Trial Feasibility Assessments: A Case Study.
Stanton, Robert J. MD ,*; Robinson, David J. MD ,*; Aziz, Yasmin N. MD; Sucharew, Heidi PhD; Khatri, Pooja MD, MSc; Broderick, Joseph P. MD; Janis, L. Scott PhD; Kemp, Stephanie BS; Mlynash, Michael MD; Lansberg, Maarten G. MD, PhD; Albers, Gregory W. MD; Saver, Jeffrey L. MD; Flaherty, Matthew L. MD; Adeoye, Opeolu MD, MS; Woo, Daniel MD, MS; Ferioli, Simona MD; Kissela, Brett M. MD, MS; Kleindorfer, Dawn O. MD
doi : 10.1161/STROKEAHA.122.041650
Clinical trial enrollment and completion is challenging, with nearly half of all trials not being completed or not completed on time. In 2014, the National Institutes of Health StrokeNet in collaboration with stroke epidemiologists from GCNKSS (Greater Cincinnati/Northern Kentucky Stroke Study) began providing proposed clinical trials with formal trial feasibility assessments.
Risk Prediction of New Intracranial Aneurysms at Follow-Up Screening in People With a Positive Family History.
Zuurbier, Charlotte C.M. MD, PhD; Bourcier, Romain MD, PhD; Constant Dit Beaufils, Pacome MSc; Redon, Richard PhD; Desal, Hubert MD, PhD; the ICAN Investigators; Bor, Anne S.E. MD, PhD; Rinkel, Gabriel J.E. MD, PhD; Greving, Jacoba P. PhD; Ruigrok, Ynte M. MD, PhD
doi : 10.1161/STROKEAHA.122.041393
In first-degree relatives of patients with aneurysmal subarachnoid hemorrhage (aSAH), the risk of an intracranial aneurysm can be predicted at initial screening but not at follow-up screening.
Relationships of Hemoglobin Concentration, Ischemic Lesions, and Clinical Outcomes in Patients With Intracerebral Hemorrhage.
Roh, David J. MD; Boehme, Amelia PhD; Mamoon, Rayan; Hooper, Destiny MD; Cottarelli, Azzurra PhD; Ji, Robin PhD; Mao, Eric; Kumar, Aditya MD; Carvalho Poyraz, Fernanda MD, PhD; Demel, Stacie L. DO, PhD; Spektor, Vadim MD; Carmona, Jerina MPH; Hod, Eldad A. MD, MS; Ironside, Natasha MBChB; Gutierrez, Jose MD, MPH; Guo, Jia PhD; Konofagou, Elisa PhD; Elkind, Mitchell S.V. MD; Woo, Daniel MD
doi : 10.1161/STROKEAHA.122.041410
Hemoglobin concentration and diffusion-weighted imaging (DWI) ischemic lesions are separately known to be associated with poor intracerebral hemorrhage (ICH) outcomes.
Prospective Validation of Computed Tomography to Identify Patients at High Risk for Stroke After Transient Ischemic Attack or Minor Stroke.
Ferguson, Emma MBBS; Yadav, Krishan MD, MSc ,,*; Sharma, Mukul MD, MSc ,*; Sivilotti, Marco L.A. MD, MSc; Emond, Marcel MD, MSc; Stiell, Ian G. MD, MSc; Stotts, Grant MD; Lee, Jacques S. MD, MSc; Worster, Andrew MD; Morris, Judy MD, MSc; Cheung, Ka Wai MD, MPH; Jin, Albert Y. MD, PhD; Oczkowski, Wieslaw J. MD; Sahlas, Demetrios J. MD; Murray, Heather E. MD, MSc; Mackey, Ariane MD; Verreault, Steve MD; Camden, Marie-Christine MD; Yip, Samuel MD; Teal, Philip MD; Gladstone, David J. MD, PhD; Boulos, Mark I. MD, MSc; Chagnon, Nicolas MD; Shouldice, Elizabeth MD; Atzema, Clare MD, MSc; Slaoui, Tarik MD; Teitelbaum, Jeanne MD; Nemnom, Marie-Joe MSc; Wells, George A. MSc, PhD; Nath, Avik MD, MSc; Perry, Jeffrey J. MD, MSc
doi : 10.1161/STROKEAHA.121.038000
Computed tomography (CT) findings of acute and chronic ischemia are associated with subsequent stroke risk in patients with transient ischemic attack. We sought to validate these associations in a large prospective cohort of patients with transient ischemic attack or minor stroke.
Multidelay Arterial Spin Labeling Versus Computed Tomography Perfusion in Penumbra Volume of Acute Ischemic Stroke.
Yan, Chuming MM ,*; Yu, Fan MM ,*; Zhang, Yingjie MBBS; Zhang, Miao MD; Li, Jingkai MBBS; Wang, Zixin MBBS; Lu, Jie MD; Ma, Qingfeng MD
doi : 10.1161/STROKEAHA.122.040759
Multidelay arterial spin labeling (ASL) is a novel perfusion method of ASL, with arterial transit time (ATT) calculated by multiple postlabeling delays to correct cerebral blood flow (CBF).
Cerebral Venous Reflux and Cerebral Amyloid Angiopathy: An Magnetic Resonance Imaging/Positron Emission Tomography Study.
Lee, Bo-Ching MD; Tsai, Hsin-Hsi MD, PhD; Liu, Chia-Ju MD; Chen, Ya-Fang MD; Tsai, Li-Kai MD, PhD; Jeng, Jiann-Shing MD, PhD; Yen, Ruoh-Fang MD, PhD
doi : 10.1161/STROKEAHA.122.040503
Cerebral venous outflow alterations contribute to central nervous system pathology in aging and neurodegenerative disorders and are potentially linked to underlying cerebral microangiopathy.
Prognostic Value of Thrombus Volume and Interaction With First-Line Endovascular Treatment Device Choice.
van Voorst, Henk MD; Bruggeman, Agnetha A.E. MD, PhD; Andriessen, Jurr MD; Hoving, Jan W. MD; Konduri, Praneeta R. MSc; Yang, Wenjin MD; Kappelhof, Manon MD, PhD; Arrarte Terreros, Nerea PhD; Roos, Yvo B.W.E.M. MD, PhD; van Zwam, Wim H. MD, PhD; van der Lugt, Aad MD, PhD; van der Hoorn, Anouk MD, PhD; Boiten, Jelis MD, PhD; Roosendaal, Stefan MD, PhD;
doi : 10.1161/STROKEAHA.122.041606
A larger thrombus in patients with acute ischemic stroke might result in more complex endovascular treatment procedures, resulting in poorer patient outcomes.
Cerebrovascular Reactivity Has Negligible Contribution to Hemodynamic Lag After Stroke: Implications for Functional Magnetic Resonance Imaging Studies.
Braban, Andra MSc; Leech, Robert PhD; Murphy, Kevin PhD; Geranmayeh, Fatemeh PhD
doi : 10.1161/STROKEAHA.122.041880
Functional magnetic resonance imaging (fMRI) is ubiquitously used to study poststroke recovery. However, the fMRI-derived hemodynamic responses are vulnerable to vascular insult which can result in reduced magnitude and temporal delays (lag) in the hemodynamic response function (HRF).
Different Changing Patterns for Stroke Subtype Mortality Attributable to High Sodium Intake in China During 1990 to 2019.
Wang, Yan MD ,,*; Wang, Jingyu MD ,,*; Chen, Shufeng MD, PhD; Li, Bingbing MD; Lu, Xiangfeng MD, PhD; Li, Jianxin MD
doi : 10.1161/STROKEAHA.122.040848
It is unclear whether sodium intake had similar effects on mortality of stroke subtypes. The purpose of this study is to compare the long-term trends in mortality of stroke subtypes attributable to high sodium intake in China during 1990 to 2019.
Poststroke Intravenous Transplantation of Human Mesenchymal Stem Cells Improves Brain Repair Dynamics and Functional Outcomes in Aged Mice.
Zhang, Wenting PhD ,,*; Pu, Hongjian PhD ,,*; Hu, Xiaoming MD, PhD; Shi, Yejie PhD; Leak, Rehana K. PhD; Anne Stetler, R. PhD; Ye, Qing MD; Lyu, Junxuan MD; Zhang, Feng MD; Wechsler, Lawrence R. MD; Chen, Jun MD
doi : 10.1161/STROKEAHA.122.041507
Stroke is the primary cause of chronic disability in the elderly, as there are no neurorestorative treatments for those who do not qualify for recanalization therapy. Experimental evidence in stroke animals suggests that transplantation of bone marrow-derived human mesenchymal stem cells (hMSCs) holds promise, but hMSC transplantation has not been systematically tested in aged animals.
Resveratrol Preconditioning Mitigates Ischemia-Induced Septal Cholinergic Cell Loss and Memory Impairments.
Lopez-Morales, Mikahela A. PhD ,,*; Escobar, Iris BS ,,,*; Saul, Isabel BS; Jackson, Charles W. BS; Ferrier, Fernando J. BS; Fagerli, Eric A. BS; Raval, Ami P. PhD, MSPH; Dave, Kunjan R. PhD; Perez-Pinzon, Miguel A. PhD
doi : 10.1161/STROKEAHA.122.040899
Cholinergic cells originating from the nuclei of the basal forebrain (BF) are critical for supporting various memory processes, yet BF cholinergic cell viability has not been explored in the context of focal cerebral ischemia. In the present study, we examined cell survival within several BF nuclei in rodents following transient middle cerebral artery occlusion.
Optogenetic Spreading Depolarizations Do Not Worsen Acute Ischemic Stroke Outcome.
Sugimoto, Kazutaka MD, PhD; Yang, Joanna BA; Fischer, Paul MD; Takizawa, Tsubasa MD, PhD; Mulder, Inge A. PhD; Qin, Tao; Erdogan, Taylan D. BS; Yaseen, Mohammad A. PhD; Sakadzic, Sava PhD; Chung, David Y. MD, PhD; Ayata, Cenk MD, PhD
doi : 10.1161/STROKEAHA.122.041351
Spreading depolarizations (SDs) are believed to contribute to injury progression and worsen outcomes in focal cerebral ischemia because exogenously induced SDs have been associated with enlarged infarct volumes.
Associations Between Long-Term Air Pollutant Exposure and 30-Day All-Cause Hospital Readmissions in US Patients With Stroke.
Tran, Phoebe M. PhD; Warren, Joshua L. PhD; Leifheit, Erica C. PhD; Goldstein, Larry B. MD; Lichtman, Judith H. PhD
doi : 10.1161/STROKEAHA.122.042265
Long-term exposure to air pollutants is associated with increased stroke incidence, morbidity, and mortality; however, research on the association of pollutant exposure with poststroke hospital readmissions is lacking.
Genetically Proxied CRP (C-Reactive Protein) Levels and Lobar Intracerebral Hemorrhage Risk.
Myserlis, Evangelos Pavlos MD ,*; Anderson, Christopher D. MD, MMSc ,,,,*; Georgakis, Marios K. MD, PhD ,,,,*
doi : 10.1161/STROKEAHA.122.041889
Recent evidence suggests that higher CRP (C-reactive protein) levels are associated with lower risk of Alzheimer disease, speculating that CRP might be involved in A[beta] clearance mechanisms. Testing this hypothesis, we explored whether genetically proxied CRP levels are also associated with lobar intracerebral hemorrhage (ICH), commonly caused by cerebral amyloid angiopathy.
Remote Diffusion-Weighted Imaging Lesions and Intracerebral Hemorrhage: A Systematic Review and Meta-Analysis.
Posener, Sacha MD; Hmeydia, Ghazi MD; Benzakoun, Joseph PhD; Oppenheim, Catherine PhD; Baron, Jean-Claude ScD; Turc, Guillaume PhD
doi : 10.1161/STROKEAHA.122.040689
Remote diffusion-weighted imaging lesions (RDWILs) in the context of spontaneous intracerebral hemorrhage (ICH) are associated with an increased risk of recurrent stroke, worse functional outcome, and death.
White Matter Hyperintensities of the Corpus Callosum Are Associated With Clinical Severity in CADASIL.
Ouin, Elisa MD, MSc; Dimitrovic, Ana MD; Grosset, Lina MD, MSc; Lebenberg, Jessica PhD; Guillonnet, Antoine MD; Guichard, Jean-Pierre MD; Herve, Dominique MD, MSc; Chabriat, Hugues MD, PhD; Jouvent, Eric MD, PhD
doi : 10.1161/STROKEAHA.122.040938
In CADASIL (Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy), clinical severity is not related to the total burden of white matter hyperintensities (WMHs), presumably because of heterogeneous underlying tissue alterations.
Assessment of Direct Oral Anticoagulant Status Using the DOASENSE Dipstick in Thrombolysis Eligible Patients With Stroke: Proof-of-Concept Study.
Tan, Peter Shuangyue BMed; Park, Peter S.W. MBBS; Cody, Ross BS, MD; Frost, Tanya MA; McNamara, Bailey BSN; Borosak, Marija MBBS; Choi, Philip M.C. MBChB
Recurrent Ischemic Stroke and Cardiovascular Outcomes in Patients With Atrial Fibrillation With Ischemic Stroke Despite Direct Oral Anticoagulants.
Hsieh, Meng-Tsang MD; Liu, Chi-Hung MD, MS; Lin, Sheng-Hsiang PhD; Lin, Po-Yu MD; Chang, Yu-Ming MD; Wang, Chun-Min MD; Chen, Chih-Hung MD; Sung, Pi-Shan MD, PhD
Carotid-Intima Media Thickness and White Matter Hyperintensities Severity Among Older Adults of Amerindian Ancestry.
Del Brutto, Oscar H. MD; Rumbea, Denisse A. MHA; Mera, Robertino M. MD, PhD
Retinoic Acid-Loaded Nanoparticles Promote Neurovascular Protection in Stroke.
Machado-Pereira, Marta MSc; Grayston, Alba PhD; Garcia-Gabilondo, Miguel BSc; Francisco, Vitor PhD; Cristovao, Ana PhD; Marto, Joao MD; Vieira, Helena PhD; Viana-Baptista, Miguel MD, PhD; Ferreira, Lino PhD; Bernardino, Liliana PhD; Rosell, Anna PhD; Ferreira, Raquel PhD
Red Blood Cell Microparticles Limit Hemorrhage Following Intracerebral Hemorrhage in Spontaneously Hypertensive Rats.
Rehni, Ashish K. PhD ,,*; Cho, Sunjoo BS ,,*; Navarro Quero, Hever DVM; Zhang, Zhexuan PhD; Dong, Chuanhui PhD; Zhao, Weizhao PhD; Perez-Pinzon, Miguel A. PhD; Koch, Sebastian MD; Jy, Wenche PhD; Dave, Kunjan R. PhD
Hot Cross Bun Sign in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy.
Ling, Chen PhD; Yan, Haotian MD; Yuan, Yun MD; Peng, Qing MD
Bilateral Medial Medullary Infarction: The Airpod Sign.
Agarwal, Shashank MD; Raz, Eytan MD; Yaghi, Shadi MD
Vein of Trolard Thrombosis in Hyperhomocysteinemia.
Shindi, Kouther MD ,*; Nejadhamzeeigilani, Hamed MD ,*
Jugular Venous Reflux as an Indicator of Innominate Vein Occlusion Responsible for Superior Ophthalmic Vein Thrombosis.
Ha, Jiyeon MD; Kim, Seondeuk MD; Lee, Han-Sang MD; Jung, Keun-Hwa MD, PhD
Hot Cross Bun Sign in Bilateral Middle Cerebellar Peduncle Infarction.
Nishida, Katsuya MD; Futamura, Naonobu MD, PhD
Nursing Science Advances in Poststroke Fatigue, Return to Work, Sleep Disorders, and Mindfulness Following Stroke.
Hinkle, Janice L. RN, PhD, CNRN; Miller, Elaine T. PhD, RN, CRRN
Imaging Advances in Stroke: Use of Advanced Neurovascular Imaging or Disruptive Innovation With Artificial Intelligence?.
Liebeskind, David S. MD; Wardlaw, Joanna M. MD
Endovascular Therapy for Basilar Artery Occlusion.
Alemseged, Fana PhD; Nguyen, Thanh N. MD; Alverne, Francisco Mont' PhD; Liu, Xinfeng PhD; Schonewille, Wouter J. PhD; Nogueira, Raul G. MD
doi : 10.1161/STROKEAHA.122.040807
AB Basilar artery occlusion is one of the most devastating neurological conditions with high risks of disability and mortality. Despite the overwhelming benefit of endovascular therapy (EVT) in the anterior circulation and observational data supporting the efficacy of EVT in the posterior circulation, evidence from randomized controlled trials in basilar artery occlusion had been lacking until recently.
Prehospital Stroke Care Part 1: Emergency Medical Services and the Stroke Systems of Care.
Zachrison, Kori S. MD, MSc; Nielsen, Victoria M. MPH; de la Ossa, Natalia Perez MD; Madsen, Tracy E. MD, PhD; Cash, Rebecca E. PhD; Crowe, Remle P. PhD; Odom, Erika C. PhD; Jauch, Edward C. MD, MS, MBA; Adeoye, Opeolu M. MD, MSc; Richards, Christopher T. MD, MSc
doi : 10.1161/STROKEAHA.122.039586
AB Acute stroke care begins before hospital arrival, and several prehospital factors are critical in influencing overall patient care and poststroke outcomes.
Stroke Learning Health Systems: A Topical Narrative Review With Case Examples.
Cadilhac, Dominique A. PhD; Bravata, Dawn M. MD; Bettger, Janet Prvu ScD; Mikulik, Robert PhD; Norrving, Bo PhD; Uvere, Ezinne O. MPH; Owolabi, Mayowa DrM; Ranta, Annemarei PhD; Kilkenny, Monique F. PhD
doi : 10.1161/STROKEAHA.122.036216
AB To our knowledge, the adoption of Learning Health System (LHS) concepts or approaches for improving stroke care, patient outcomes, and value have not previously been summarized.
Improving Stroke Measure Compliance and Outcomes Through Hospital Collaboration.
Moore, Kari D. MSN, RN, AGACNP-BC, ANVP-BC; Summers, Debbie MSN, RN, AHCNS-BC; Wilson, Susan E. DNP, ANP-BC
doi : 10.1161/STROKEAHA.122.038458
AB Globally, national stroke registries have been shown to improve the quality of patient care and outcomes. However, registry utilization and implementation vary by country.
April Stroke Literature Synopses (Preclinical).
Branyan, Taylor E.; Sohrabji, Farida PhD
How to Keep Your (Stroke) Trial Alive?.
Arnold, Markus MD; Kaesmacher, Johannes MD; Katan, Mira MD, MS
Liability Before Diagnosis: Failure to Admit in a Stroke Case.
Liang, Bryan A. MD, PhD, JD; Maroulis, James MAS, JD; Mackey, Tim K. MAS, PhD
Ideal Foundational Requirements for Stroke Program Development and Growth: A Scientific Statement From the American Heart Association.
Dusenbury, Wendy PhD, DNP, FAHA, Chair; Mathiesen, Claranne MSN, FAHA, Vice Chair; Whaley, Michelle MSN; Adeoye, Opeolu MD, MS, FAHA; Leslie-Mazwi, Thabele MD; Williams, Shavonne MN; Velasco, Cesar BSN; Shah, Samarth P. PharmD; Gonzales, Nicole R. MD, FAHA; Alexandrov, Anne W. PhD; on behalf of the American Heart Association Council on Cardiovascular and Stroke Nursing and the Stroke Council
doi : 10.1161/STR.0000000000000424
AB Stroke center certification has evolved at a rapid pace and is now available at 4 different levels of service in the United States. Although certification standards provide guidance on stroke center process elements, lack of guidance on structural components such as workforce, staffing, and unit operations has resulted in heterogeneous services among hospitals credentialed at the same stroke center level.
Correction to: Intensive Social Interaction for Treatment of Poststroke Depression in Subacute Aphasia: The CONNECT Trial.
