New England Journal of Medicine




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سفارش

Ensuring Public Trust in an Empowered FDA

Joseph S. Ross, M.D., M.H.S., Karina M. Berg, M.D., and Reshma Ramachandran, M.D., M.P.P., M.H.S.

doi : 10.1056/NEJMp2300438

Vol. 388 No. 14

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Why Diverse Clinical Trial Participation Matters

Aaron L. Schwartz, M.D., Ph.D., Marcella Alsan, M.D., Ph.D., Alanna A. Morris, M.D., and Scott D. Halpern, M.D., Ph.D.

doi : 10.1056/NEJMp2215609

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A Quixotic Quest for Independence — Benefits, Risks, and the Human Heart

Stephen Landy, M.D.

doi : 10.1056/NEJMp2216655

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Trial of Endovascular Thrombectomy for Large Ischemic Strokes

Amrou Sarraj, M.D., Ameer E. Hassan, D.O., Michael G. Abraham, M.D., Santiago Ortega-Gutierrez, M.D., Scott E. Kasner, M.D., M. Shazam Hussain, M.D., Michael Chen, M.D., Spiros Blackburn, M.D., Clark W. Sitton, M.D., Leonid Churilov, Ph.D., Sophia Sundararajan, M.D., Yin C. Hu, M.D.,

doi : 10.1056/NEJMoa2214403

Trials of the efficacy and safety of endovascular thrombectomy in patients with large ischemic strokes have been carried out in limited populations.

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Trial of Endovascular Therapy for Acute Ischemic Stroke with Large Infarct

Xiaochuan Huo, M.D., Ph.D., Gaoting Ma, M.D., Ph.D., Xu Tong, M.D., Ph.D., Xuelei Zhang, M.D., Ph.D., Yuesong Pan, Ph.D., Thanh N. Nguyen, M.D., Guangxiong Yuan, M.D., Hongxing Han, Ph.D., Wenhuo Chen, Ph.D., Ming Wei, M.D., Jiangang Zhang, M.D., Zhiming Zhou, M.D., Xiaoxi Yao, B.S., Guoqing Wang, M.D., Weigen Song, B.S., Xueli Cai, Ph.D., Guangxian Nan, M.D., Di Li, M.D., A. Yi-Chou Wang, Ph.D., Wentong Ling, B.S., Chuwei Cai, Ph.D., Changming Wen, Ph.D., En Wang, Ph.D., Liyong Zhang, M.D., Changchun Jiang, Ph.D., Yajie Liu, M.D., Geng Liao, Ph.D., Xiaohui Chen, M.D., Tianxiao Li, M.D., Shudong Liu, M.D., Jinglun Li, M.D., Feng Gao, M.D., Ph.D., Ning Ma, M.D., Ph.D., Dapeng Mo, M.D., Ph.D., Ligang Song, M.D., Xuan Sun, M.D., Ph.D., Xiaoqing Li, M.D., Ph.D., Yiming Deng, M.D., Ph.D., Gang Luo, M.D., Ph.D., Ming Lv, M.D., Hongwei He, M.D., Aihua Liu, M.D., Jingbo Zhang, M.D., Shiqing Mu, M.D., Lian Liu, M.D., Jing Jing, Ph.D., Ximing Nie, M.D., Zeyu Ding, M.D., Wanliang Du, M.D., Xingquan Zhao, M.D., Ph.D., Pengfei Yang, M.D., Ph.D., Liping Liu, M.D., Ph.D., Yilong Wang, M.D., Ph.D., David S. Liebeskind, M.D., Vitor M. Pereira, Ph.D., Zeguang Ren, M.D., Yongjun Wang, M.D., Ph.D., and Zhongrong Miao, M.D., Ph.D. for the ANGEL-ASPECT Investigators*

doi : 10.1056/NEJMoa2213379

The role of endovascular therapy for acute stroke with a large infarction has not been extensively studied in differing populations.

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GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma

Francesca Del Bufalo, M.D., Biagio De Angelis, Ph.D., Ignazio Caruana, Ph.D., Giada Del Baldo, M.D., Maria A. De Ioris, M.D., Ph.D., Annalisa Serra, M.D., Angela Mastronuzzi, M.D., Ph.D., Maria G. Cefalo, M.D., Daria Pagliara, M.D., Matteo Amicucci, M.S.N., Giuseppina Li Pira, Ph.D., Giovanna Leone, M.D., Valentina Bertaina, Ph.D., Matilde Sinibaldi, Ph.D., Stefano Di Cecca, Ph.D., Marika Guercio, Ph.D., Zeinab Abbaszadeh, Ph.D., Laura Iaffaldano, Ph.D., Monica Gunetti, Ph.D., Stefano Iacovelli, Ph.D., Rossana Bugianesi, Ph.D., Stefania Macchia, Ph.D., Mattia Algeri, M.D., Pietro Merli, M.D., Federica Galaverna, M.D., Ph.D., Rachid Abbas, Ph.D., Maria C. Garganese, M.D., Maria F. Villani, M.D., Giovanna S. Colafati, M.D., Federico Bonetti, M.D., Marco Rabusin, M.D., Katia Perruccio, M.D., Veronica Folsi, M.D., Concetta Quintarelli, Ph.D., and Franco Locatelli, M.D., Ph.D. for the Precision Medicine Team–IRCCS Ospedale Pediatrico Bambino Gesù*

doi : 10.1056/NEJMoa2210859

Immunotherapy with chimeric antigen receptor (CAR)–expressing T cells that target the disialoganglioside GD2 expressed on tumor cells may be a therapeutic option for patients with high-risk neuroblastoma.

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Postexposure Doxycycline to Prevent Bacterial Sexually Transmitted Infections

Anne F. Luetkemeyer, M.D., Deborah Donnell, Ph.D., Julia C. Dombrowski, M.D., M.P.H., Stephanie Cohen, M.D., M.P.H., Cole Grabow, M.P.H., Clare E. Brown, Ph.D., Cheryl Malinski, B.S., Rodney Perkins, R.N., M.P.H., Melody Nasser, B.A., Carolina Lopez, B.A., Eric Vittinghoff, Ph.D., Susan P. Buchbinder, M.D., Hyman Scott, M.D., M.P.H., Edwin D. Charlebois, Ph.D., M.P.H., Diane V. Havlir, M.D., Olusegun O. Soge, Ph.D., and Connie Celum, M.D., M.P.H. for the DoxyPEP Study Team*

doi : 10.1056/NEJMoa2211934

Interventions to reduce sexually transmitted infections (STIs) among men who have sex with men (MSM) are needed.

خرید پکیج و مشاهده آنلاین مقاله


Primary Budd–Chiari Syndrome

Juan Carlos Garcia-Pagán, M.D., Ph.D., and Dominique-Charles Valla, M.D.

doi : 10.1056/NEJMra2207738

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Acute Ocular Toxoplasmosis

Wan-Hua Cho, M.D., and Wan-Ju A. Lee, M.D., Ph.D.

doi : 10.1056/NEJMicm2211525

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Palmar Erythema of Pregnancy

Kenneth Katz, M.D.

doi : 10.1056/NEJMicm2210742

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An Alternate Explanation

Tom Alsaigh, M.D., Gurpreet Dhaliwal, M.D., Eri Fukaya, M.D., Ph.D., Nicholas J. Leeper, M.D., and Nazish Sayed, M.D., Ph.D.

doi : 10.1056/NEJMcps2210419

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Improved Prospects for Thrombectomy in Large Ischemic Stroke

Pierre Fayad, M.D.

doi : 10.1056/NEJMe2300193

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CAR T Cells for Neuroblastoma

Oladapo O. Yeku, M.D., Ph.D., and Dan L. Longo, M.D.

doi : 10.1056/NEJMe2300317

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Understanding the Genetic Risk of IDH-Mutant Glioma

Tracy T. Batchelor, M.D., M.P.H., and Kyle M. Walsh, Ph.D.

doi : 10.1056/NEJMcibr2213112

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Viral Lineages in the 2022 RSV Surge in the United States

doi : 10.1056/NEJMc2216153

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Cambridge Prophylactic Protocol, Retinal Detachment, and Stickler Syndrome

doi : 10.1056/NEJMc2211320

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Progression of Atrial Fibrillation after Cryoablation

doi : 10.1056/NEJMc2301604

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Chlorthalidone vs. Hydrochlorothiazide for Hypertension–Cardiovascular Events

doi : 10.1056/NEJMc2301922

خرید پکیج و مشاهده آنلاین مقاله


Evidence over Politics — U.S. Preventive Services Task Force

doi : 10.1056/NEJMc2301322

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