JONES JR, LYELL K. MD, FAAN
Meschia, James F. MD, FAAN
doi : 10.1212/CON.0000000000001206
Precise therapies require precise diagnoses. This article provides an evidence-based approach to confirming the diagnosis of ischemic stroke, characterizing comorbidities that provide insights into the pathophysiologic mechanisms of stroke, and identifying targets for treatment to optimize the prevention of recurrent stroke.
Grotta, James C. MD, FAAN
doi : 10.1212/CON.0000000000001207
This article reviews the history of IV thrombolysis, its current indications and implementation, the duality of the "time is brain" versus "tissue clock" approaches, the impact of endovascular thrombectomy on IV thrombolysis, the emergence of tenecteplase, and future research directions
Sheth, Sunil A. MD
doi : 10.1212/CON.0000000000001243
Endovascular stroke therapy has greatly improved the ability to treat the deadliest and most disabling form of acute ischemic stroke. This article summarizes some of the recent innovations in this field and discusses likely future developments.
Yaghi, Shadi MD, FAHA
doi : 10.1212/CON.0000000000001217
Cardioembolic stroke accounts for nearly 30% of ischemic strokes. Prompt diagnosis of the underlying mechanism may improve secondary prevention strategies. This article reviews recent randomized trials, observational studies, case reports, and guidelines on the diagnosis and treatment of cardioembolic stroke.
Chaturvedi, Seemant MD, FAAN, FAHA
doi : 10.1212/CON.0000000000001212
Ischemic stroke due to large vessel atherosclerosis is a significant cause of stroke globally. With the aging population, the number of people with atherosclerotic stroke will increase in the coming decades.
Sharrief, Anjail MD, MPH, FAHA
doi : 10.1212/CON.0000000000001232
Cerebral small vessel disease (CSVD) is a common neurologic condition that contributes to considerable mortality and disability because of its impact on ischemic and hemorrhagic stroke risk and dementia.
Liberman, Ava L. MD
doi : 10.1212/CON.0000000000001211
Cerebral venous thrombosis (CVT), thrombosis of the dural sinus, cerebral veins, or both, is a rare cerebrovascular disease. Although mortality rates after CVT have declined over time, this condition can result in devastating neurologic outcomes.
Omran, Setareh Salehi MD
doi : 10.1212/CON.0000000000001233
Cervical artery dissection is a common cause of stroke in young adults. This article reviews the pathophysiology, etiology and risk factors, evaluation, management, and outcomes of spontaneous cervical artery dissection.
Fox, Christine MD, MAS
doi : 10.1212/CON.0000000000001239
Pediatric cerebrovascular disease is one of the leading causes of death and disability in children. Survivors of childhood stroke and their families are often left to cope with long-lasting sequelae, such as barriers to school reentry and long-term challenges in attaining independence as adults.
Nguyen, Thanh Ngoc MD, FRCPc, FSVIN, FAHA
doi : 10.1212/CON.0000000000001247
Managing a patient with an unruptured brain aneurysm or brain arteriovenous malformation (AVM) can lead to uncertainty about preventive treatment. While the bleeding risks are low, the morbidity or mortality associated with a hemorrhagic event is not insignificant.
O'Dell, Michael W. MD
doi : 10.1212/CON.0000000000001218
Up to 50% of the nearly 800,000 patients who experience a new or recurrent stroke each year in the United States fail to achieve full independence afterward. More effective approaches to enhance motor recovery following stroke are needed.
Villanueva, Raissa MD, MPH, FAAN; Busis, Neil A. MD, FAAN; Cohen, Bruce H. MD, FAAN; Ciccarelli, Luana CPC, CRC
doi : 10.1212/CON.0000000000001301
AB Landmark changes to documenting and coding for office or other outpatient evaluation and management (E/M) codes were implemented on January 1, 2021. To decrease clinicians' administrative burden, many documentation requirements were eliminated. In addition, major changes were made in how medical decision making and time spent on the date of the encounter are used to determine the level of service. On January 1, 2023, these changes were extended to inpatient and observation E/M services.
Gelb, Douglas MD, PhD, FAAN; Zazulia, Allyson R. MD
Gelb, Douglas MD, PhD, FAAN; Zazulia, Allyson R. MD
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