Digestive Diseases and Sciences




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سفارش

One Case of Epstein–Barr Virus Encephalitis from Pediatric Crohn’s Disease After 6-Mercaptopurine and Infliximab Treatment

Jindan Yu, Yao Lv, Youyou Luo, Youhong Fang & Jie Chen

doi : 10.1007/s10620-022-07801-4

Volume 68, issue 5, May 2023

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Refractory Ulcerative Colitis Requiring Preoperative Suction Thrombectomy of Submassive Bilateral Pulmonary Emboli Before Total Abdominal Colectomy

Mujtaba Mubashir, Casey Carnell, Ihab Haddadin & Stefan D. Holubar

doi : 10.1007/s10620-023-07843-2

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A Rare Case of Cholangiocarcinosarcoma Masquerading as a Cholangiolithiasis Observed by ERCP

Haiming Zheng, Qian Zhuang & Xinjian Wan

doi : 10.1007/s10620-023-07836-1

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Is Evidence of Absence Considered Absence of Evidence? How Negative Studies Inform Shared Decision-Making

Eric D. Shah

doi : 10.1007/s10620-023-07878-5

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Deep Cuts: Colonic Polyp Resection Using Standard Endoscopic Mucosal Resection vs. Precutting Endoscopic Mucosal Resection Using a Novel Disk Tip Snare

Dhruvil Radadiya 

doi : 10.1007/s10620-023-07851-2

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Lost in Translation? Avoiding Post-colonoscopy Colon Cancer

Nicholas V. Costrini 

doi : 10.1007/s10620-023-07877-6

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Spontaneous Bacterial Peritonitis: The Bug Matters

Sunny Sandhu & Binu V. John

doi : 10.1007/s10620-023-07865-w

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Simulated Reality: How Endoscopic Simulators Improve GI Fellow Procedural Training?

Joseph C. Yarze

doi : 10.1007/s10620-023-07919-z

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Comprehensive Review: Acute Esophageal Necrosis in the Setting of Gastric Volvulus

Moniyka Sachar, Erick Arguetta & Grigoriy E. Gurvits

doi : 10.1007/s10620-023-07869-6

Acute esophageal necrosis (AEN) in the setting of gastric volvulus is a rare condition with only a handful of cases reported. Volvulus may contribute to AEN by limiting tissue perfusion and promoting massive reflux of gastric contents on compromised esophageal mucosa.

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Current and Future Therapeutic Options for Irritable Bowel Syndrome with Diarrhea and Functional Diarrhea

Gabriela Piovezani Ramos & Michael Camilleri

doi : 10.1007/s10620-022-07700-8

Irritable bowel syndrome with diarrhea and functional diarrhea are disorders of gut-brain interaction presenting with chronic diarrhea; they have significant impact on quality of life. The two conditions may exist as a continuum and their treatment may overlap.

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Why the Vonoprazan Helicobacter pylori Therapies in the US-European Trial Produced Unacceptable Cure Rates

David Y. Graham

doi : 10.1007/s10620-023-07886-5

Helicobacter pylori infects a large percentage of the world’s population and is etiologically related to gastric cancer. The U.S. Food and Drug Administration recently approved two 14-day vonoprazan-containing regimens (vonoprazan–amoxicillin with or without clarithromycin) for H. pylori infections in the United States/Europe.

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Y Not Roux-en-Y?: Resolution of Barrett’s Esophagus After Surgical Conversion of Gastric Sleeve in Two Patients

Lidia Castagneto-Gissey, Loredana Gualtieri, Annalisa Diddoro, Augusto Lauro, Alfredo Genco & Giovanni Casella

doi : 10.1007/s10620-023-07874-9

Esophageal lesions ranging from erosive esophagitis to Barrett's esophagus (BE) eventually develop months—years after sleeve gastrectomy (SG), representing a significant post-surgical issue in GI practice.

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Author Spotlight: Lidia Castagneto-Gissey

Lidia Castagneto-Gissey 

doi : 10.1007/s10620-023-07875-8

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Rise over Runs: Elevated Creatinine and a New Diagnosis of Inflammatory Bowel Disease

Fernando S. Velayos

doi : 10.1007/s10620-023-07852-1

A 32-year-old man with a 3-month history of intermittent diarrhea was noted to have an elevated creatinine of 2.2 mg/dL, with no prior results available. Colonoscopy revealed mucosal inflammation characterized by the loss of vascular pattern and erosions throughout the colon with sparing of the rectum.

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Excipient Exception: A Complication of Infliximab and Vedolizumab Infusions for Ulcerative Colitis

Rahul S. Dalal, Behiye Goksel & Matthew J. Hamilton

doi : 10.1007/s10620-023-07866-9

A 32-year-old female with no significant past medical history was diagnosed with ulcerative proctitis in the setting of abdominal pain and hematochezia following a miscarriage. Index colonoscopy with biopsies demonstrated mild chronic active colitis in the rectum with normal histology throughout the remainder of the colon and terminal ileum.

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A Nationwide Survey of Gastroenterology Program Leadership Regarding Implementation of the GI Hospitalist Model

Ryan Flanagan, Mayssan Muftah, Molly Perencevich, Walter Chan & Daniel J. Stein

doi : 10.1007/s10620-022-07763-7

Academic gastroenterology (GI) hospitalists are increasing, however the impacts on fellowship training and clinical care are unclear. Motivations for implementation of the GI hospitalist model are uninvestigated.

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An Expert Consensus to Standardize Assessment of Bowel Cleansing for Clinical Trials of Bowel Preparations for Crohn’s Disease

Jennifer K. Maratt, Corey A. Siegel, Alan N. Barkun, Yoram Bouhnik, Brian Bressler, Audrey H. Calderwood, James E. East, Monika Fischer, Johannes Grossmann, Joshua R. Korzenik, Stacy B. Menees, Julian Panes, Douglas K. Rex, Michael S. L. Sey, Michael K. Allio, K. Adam Baker, Leonardo Guizzetti, Julie Remillard, Rocio Sedano, Brian G. Feagan, Christopher Ma & Vipul Jairath

doi : 10.1007/s10620-022-07775-3

Despite regular need for colonoscopy in patients with Crohn’s disease (CD), the efficacy and tolerability of bowel preparation (BP) agents is rarely assessed in this population. Assessing BP quality with existing scales may be challenging in CD due to presence of inflammation, bowel resection, and strictures.

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Evaluation of the Application Effect of a New Anti-reflux Water Injection Tube Device in the Prevention of the Contamination of Endoscopy Water Injection Bottles

Yingjing Liu, Shenting Xu, Gulizeba Muhetaer, Hao Tang, Hongtao Guo & Hang Li

doi : 10.1007/s10620-022-07796-y

Water delivery tube reflux during gastrointestinal endoscopy examination is widespread and it is the leading cause of water injection bottle pollution.

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A Population-Based Helicobacter pylori Eradication Strategy Is More Cost-Effective than Endoscopic Screening

Akiko Kowada 

doi : 10.1007/s10620-022-07795-z

Helicobacter pylori (HP) eradication therapy is an efficient primary prevention method to reduce gastric cancer development. In Japan, biennial endoscopic screening for individuals aged 50 years and older is currently conducted as a national gastric cancer prevention program.

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Endoscopic Retrograde Cholangiopancreatography Performed by Trainees Is Not Associated with Increased Immediate Adverse Events or Technical Failure Rates

Osayande Osagiede, Frank J. Lukens, Vivek Kumbhari & Juan E. Corral

doi : 10.1007/s10620-022-07753-9

Training endoscopists to perform endoscopic retrograde cholangiopancreatography (ERCP) is critical to address the increasing patient population with pancreatobiliary diseases. Concerns remain about ERCP safety and success involving trainees. We compared the technical success and immediate adverse events between ERCP with and without trainee involvement.

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Pancreatic Enzyme Replacement Therapy in Patients with Non-pancreatic Digestive Conditions: A Nationwide Claims Analysis

Anna Evans Phillips, Gong Tang, Xianling Wang, Christopher E. Forsmark & Dhiraj Yadav

doi : 10.1007/s10620-022-07750-y

Pancreatic enzyme replacement therapy (PERT) is most commonly used to treat exocrine insufficiency related to pancreatic diseases, but can be used for non-pancreatic digestive conditions (NPDC). We aimed to determine the prevalence of PERT use and describe prescription patterns in individuals with NPDC.

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A Gallbladder Cancer Survival Prediction Model Based on Multimodal Fusion Analysis

Ziming Yin, Tao Chen, Yijun Shu, Qiwei Li, Zhiqing Yuan, Yijue Zhang, Xinsen Xu & Yingbin Liu

doi : 10.1007/s10620-022-07782-4

Gallbladder cancer is the sixth most common malignant gastrointestinal tumor. Radical surgery is currently the only effective treatment, but patient prognosis is poor, with a 5-year survival rate of only 5–10%. Establishing an effective survival prediction model for gallbladder cancer patients is crucial for disease status assessment, early intervention, and individualized treatment approaches.

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Durability of FIT Screening After Cessation of a Screening Outreach Intervention

Shohei Burns & Ma Somsouk

doi : 10.1007/s10620-022-07755-7

Organized outreach to increase CRC screening using mailed FIT tests has been shown to be effective, but durable changes to screening behavior after cessation of screening is not known.

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Long-Term Impact of Medicaid Expansion on Colorectal Cancer Screening in Its Targeted Population

Zhiyu Qian, Xi Chen, Daniel Pucheril, Khalid Al Khatib, Mayra Lucas, David-Dan Nguyen, Julia McNabb-Baltar, Stuart R. Lipsitz, Nelya Melnitchouk, Alexander P. Cole & Quoc-Dien Trinh

doi : 10.1007/s10620-022-07797-x

Colorectal cancer screening continuously decreased its mortality and incidence. In 2010, the Affordable Care Act extended Medicaid eligibility to low-income and childless adults. Some states elected to adopt Medicaid at different times while others chose not to. Past studies on the effects of Medicaid expansion on colorectal cancer screening showed equivocal results based on short-term data following expansion.

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Telephone-Only Visits Preserved Hepatocellular Cancer Screening Rates in Patients with Cirrhosis Early in the COVID-19 Pandemic

Sean Richard Rudnick, Judy Ugwuegbu, Stephen James Soufleris, Richa Bundy, Ajay Dharod & Mark William Russo

doi : 10.1007/s10620-022-07786-0

The coronavirus 2019 (COVID-19) pandemic required an immediate and large-scale transition to telemedicine. Telemedicine includes phone visits and video visits. Studies suggest that hepatocellular cancer (HCC) screening rates fell at the beginning of the COVID-19 pandemic. If left unaddressed, HCC morbidity/mortality may increase following the pandemic due to inadequate screening.

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Cystic Fibrosis-Related Gut Dysbiosis: A Systematic Review

L. R. Caley, H. White, M. C. de Goffau, R. A. Floto, J. Parkhill, B. Marsland & D. G. Peckham

doi : 10.1007/s10620-022-07812-1

Cystic Fibrosis (CF) is associated with gut dysbiosis, local and systemic inflammation, and impaired immune function. Gut microbiota dysbiosis results from changes in the complex gut milieu in response to CF transmembrane conductance regulator (CFTR) dysfunction, pancreatic malabsorption, diet, medications, and environmental influences.

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Hypotonicity-Induced Increase in Duodenal Mucosal Permeability Is Regulated by Cholinergic Receptors in Rats

David Dahlgren, Olof Nylander & Markus Sjöblom

doi : 10.1007/s10620-022-07764-6

The role of cholinergic receptors in the regulation of duodenal mucosal permeability in vivo is currently not fully described.

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Ameliorating Role of Hydrogen-Rich Water Against NSAID-Induced Enteropathy via Reduction of ROS and Production of Short-Chain Fatty Acids

Yoshihiro Akita, Masaaki Higashiyama, Chie Kurihara, Suguru Ito, Shin Nishii, Akinori Mizoguchi, Kenichi Inaba, Rina Tanemoto, Nao Sugihara, Yoshinori Hanawa, Akinori Wada, Kazuki Horiuchi, Yoshikiyo Okada, Kazuyuki Narimatsu, Shunsuke Komoto, Kengo Tomita, Fumie Takei, Yasushi Satoh, Masayuki Saruta & Ryota Hokari

doi : 10.1007/s10620-022-07781-5

Nonsteroidal anti-inflammatory drug (NSAID)-induced enteropathy, the mechanism of which is involved in oxidative stress, can be lethal due to hemorrhage. Thus, we aimed to investigate the effect of hydrogen-rich water (HRW), in terms of oxidative stress, on intestinal mucosal damage as well as changes in the gut microbiome and the short-chain fatty acids (SCFAs) content in feces.

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Mesenchymal Stem Cells Promote Intestinal Mucosal Repair by Positively Regulating the Nrf2/Keap1/ARE Signaling Pathway in Acute Experimental Colitis

Peng Liu, Xiao-ran Xie, Hao Wu, Huan Li, Jing-shu Chi, Xiao-ming Liu, Ju Luo, Yu Tang & Can-xia Xu

doi : 10.1007/s10620-022-07722-2

Mesenchymal stem cells (MSCs) are a type of adult pluripotent stem cell that has anti-inflammatory and immunomodulatory effects, and whose conditioned medium (CM) has also been found to be effective. We used MSC and CM enemas to investigate their ameliorative effects in a mouse model of colitis.

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Aberrant NSG1 Expression Promotes Esophageal Squamous Cell Carcinoma Cell EMT by the Activation of ERK Signaling Pathway

Xiaoqing Lin, Mingshu Tu, Yi Zhang, Wanzhen Zhuang, Liqing Cai, Liangming Zhang, Lili Yu, Zhenlong Zhang & Yi Huang

doi : 10.1007/s10620-022-07748-6

Neuron-specific gene family member 1 (NSG1) is a 21 kDa endosomal protein that is specifically expressed in neurons.

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Interleukin-10 Knockout Mice Do Not Reliably Exhibit Macroscopic Inflammation: A Natural History Endoscopic Surveillance Study

Seung Young Kim, Jae Ho Park, Gabriela Leite, Mark Pimentel & Ali Rezaie

doi : 10.1007/s10620-023-07871-y

Interleukin (IL)-10 knockout (KO) mice, a model for inflammatory bowel disease (IBD), develop chronic enterocolitis due to an aberrant immune response to enteric antigens. Endoscopy, the gold standard for evaluation of human mucosal health, is not widely available for murine models.

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Concise Commentary: An Imperfect 10—Unexpected Resolution of Spontaneous Colitis in Serially Endoscoped IL-10-/-Mice

Amber Hanif Palla 

doi : 10.1007/s10620-023-07879-4

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Expression of 5-HT Relates to Stem Cell Marker LGR5 in Patients with Gastritis and Gastric Cancer

Qian Niu, Lin Li, Caili Zhang, Changhai Qi, Qiufeng He & Yuanmin Zhu

doi : 10.1007/s10620-022-07772-6

5-Hydroxytryptamine (5-HT) and stem cells marker G-protein-coupled receptor 5 (LGR5) are associate with gastrointestinal inflammation and tumorigenesis. But the relationship between 5-HT and LGR5 is unclear.

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Downregulation of SLC9A8 Promotes Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer Cells via the IL6-JAK1/STAT3 Signaling Pathway

Wei Liu, Chong Geng, Xiao Li, Yanni Li, Shuailing Song & Chunhui Wang

doi : 10.1007/s10620-022-07805-0

SLC9A8 has been shown to be involved in mucus layer formation, intestinal mucosal integrity, and hyperproliferation of colitis-associated tumor development. However, its effects on the epithelial–mesenchymal transition (EMT) and the metastasis of colorectal cancer (CRC) remain unknown.

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Establishment of a Novel Colitis-Associated Cancer Mouse Model Showing Flat Invasive Neoplasia

Tomio Uragami, Yugo Ando, Mamiko Aoi, Toshiro Fukui, Yasushi Matsumoto, Shunsuke Horitani, Takashi Tomiyama, Kazuichi Okazaki, Koichi Tsuneyama, Hajime Tanaka & Makoto Naganuma

doi : 10.1007/s10620-022-07774-4

Chronic inflammation, such as ulcerative colitis, increases the risk of developing colitis-associated cancers. Currently, mice administered with azoxymethane/dextran sodium sulfate are well-known models for colitis-associated cancers. Although human colitis-associated cancers are often flat lesions, most azoxymethane/dextran sodium sulfate mouse cancers are raised lesions.

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Role of Up-Regulated Transmembrane Channel-Like Protein 5 in Pancreatic Adenocarcinoma

Xiang-Yu Gan, Jian-Di Li, Gang Chen, Rong-Quan He, Jia-Yuan Luo, Jing-Jing Zeng, Zi-Xuan Yang, Yu-Xuan Yao, Jun-Jie Zhu, Jian-Jun Li & Dan-Ming Wei

doi : 10.1007/s10620-022-07771-7

Pancreatic adenocarcinoma (PAAD) is a malignant tumor responsible for a heavy disease burden. Previously, only one pan-cancer study of Transmembrane channel-like protein 5 (TMC5) showed that TMC5 was highly expressed in PAAD, but the results lacked comprehensive verification, and the mechanism of TMC5 in PAAD was still unclear.

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FBXO22 Accelerates Pancreatic Cancer Growth by Deactivation of the Hippo Pathway via Destabilizing LATS2

Jingsheng Ma, Yajun Wu, Shibao Cheng, Wentao Yang, Lin Zhong, Qigen Li & Lu Fang

doi : 10.1007/s10620-022-07780-6

Dysregulation of ubiquitin ligases plays a crucial role in the development and progression of various human tumors. F-box only protein 22 (FBXO22), an F-box E3 ubiquitin ligase, has been reported to participate in diverse aspects of cancer progression. However, the clinical significance and biological function of FBXO22 in pancreatic cancer remain poorly understood.

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miR-29c Suppresses the Malignant Phenotype of Hepatocellular Carcinoma Cells In Vitro by Mediating TPX2 Associated with Immune Infiltration

Haibo Wang, Wanjin Chen, Yong Qi, Deng Liu, Zhiqiang Liu, Qikun Zhang, Yujiao Yi, Juanru Wang & Wenyong Wu

doi : 10.1007/s10620-022-07810-3

miR-29-3p, an important tumor suppressor, with inhibitory effects in multiple cancers that have been studied. Its exact molecular function is in HCC, however, still not been explored clearly. The purpose of our study is to make certain how miR-29c-3p affects HCC through TPX2.

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Argon Plasma Coagulation of Gastric Inlet Patches of the Cervical Esophagus Relieves Vocal and Respiratory Symptoms in Selected Patients

Thorsten Brechmann, Maximilian Mühlenkamp, Wolff Schmiegel & Bernd Viebahn

doi : 10.1007/s10620-022-07745-9

Argon plasma coagulation (APC) of gastric inlet patches of the cervical esophagus (GIP) has been shown to relieve the globus sensation. This study aimed to investigate the long-term effects of APC therapy on a variety of laryngopharyngeal symptoms.

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Children With Celiac Disease Consume Specific Food Additives More Frequently Compared to Children Without Celiac Disease

Erin McDonnell, Johanna W. Lampe, Mason Nuding & Dale Lee

doi : 10.1007/s10620-022-07792-2

Gluten-free foods often contain food additives to improve palatability, but the long-term effects on the human gastrointestinal tract are not well known.

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Risk of Bleeding with Endoscopic Ultrasound-Guided Tissue Acquisition in Patients on Antithrombotic Therapy: A Systematic Review and Meta-Analysis

Suprabhat Giri, Shivaraj Afzalpurkar, Prajna Anirvan, Sumaswi Angadi, Sunil Kasturi, Jijo Varghese & Sridhar Sundaram

doi : 10.1007/s10620-022-07808-x

The present guidelines stratify endoscopic ultrasound-guided tissue acquisition (EUS-TA) as a high-bleeding risk procedure in patients on antithrombotics. However, the data regarding the same are conflicting. Therefore, this meta-analysis aimed to analyze the bleeding event rates associated with EUS-TA in patients receiving antithrombotic therapy.

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Upper Gastrointestinal Bleeding Due to a Left Gastric Artery Pseudoaneurysm: A Case Series

Seokin Kang, Kee Don Choi, Yuri Kim, Hee Kyong Na, Jeong Hoon Lee, Ji Yong Ahn, Kee Wook Jung, Do Hoon Kim, Ho June Song, Gin Hyug Lee & Hwoon-Yong Jung

doi : 10.1007/s10620-022-07776-2

Left gastric artery (LGA) pseudoaneurysm presenting with upper gastrointestinal (UGI) bleeding is rare but fatal, unless treated.

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Dual Antiplatelet Therapy Does Not Increase Bleeding Risk in Percutaneous Gastrostomy Tube Placement: Network Meta-Analysis

Manesh Kumar Gangwani, Muhammad Aziz, Abeer Aziz, Fnu Priyanka, Arti Patel, Umar Ghaffar, Simcha Weissman, Mahmood Asif, Wade Lee-Smith, Toseef Javaid, Ali Nawras & Benjamin Hart

doi : 10.1007/s10620-022-07804-1

Gastrostomy tube (G tube) is a commonly performed procedure for nutritional support. Current guidelines recommend discontinuation of dual antiplatelet therapy (DAPT) prior to G tube placement to reduce bleeding risk.

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Risk of Gastrointestinal Bleeding with Concurrent Use of NSAID and SSRI: A Systematic Review and Network Meta-Analysis

Hossein Haghbin, Nuruddinkhodja Zakirkhodjaev, Faiza Fatima Husain, Wade Lee-Smith & Muhammad Aziz

doi : 10.1007/s10620-022-07788-y

Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used over-the-counter medications that can increase the risk of gastrointestinal (GI) bleeding through antiplatelet effects and loss of GI protection.

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Ustekinumab and Vedolizumab Are Equally Safe and Effective in Elderly Crohn’s Disease Patients

Gerum Gashaw Gebeyehu, Joseph Fiske, Eleanor Liu, Jimmy K. Limdi, Giacomo Broglio, Christian Selinger, Violeta Razsanskaite, Philip J. Smith, Paul K. Flanagan & Sreedhar Subramanian

doi : 10.1007/s10620-022-07770-8

Anti-tumour necrosis factor (anti-TNF) agents are associated with increased infection risk among elderly inflammatory bowel disease (IBD) patients, and thus, alternative biologics may be preferable. However, little comparative data exist on the safety and efficacy of vedolizumab and ustekinumab in elderly IBD patients.

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Early Infliximab Clearance Predicts Remission in Children with Crohn’s Disease

Aaron Chung, Matthew Carroll, Patricia Almeida, Alexandra Petrova, Daniela Isaac, Diane Mould, Eytan Wine & Hien Huynh

doi : 10.1007/s10620-022-07783-3

Children with Crohn’s disease have lower response rates to infliximab, lower infliximab levels, and higher infliximab clearance on weight-based dosing than adults. We hypothesize infliximab clearance is a predictive of later outcomes on infliximab in children with Crohn’s disease.

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Delivery of Fecal Material to Terminal Ileum Is Associated with Long-Term Success of Fecal Microbiota Transplantation

Alexa R. Weingarden, Olivia Treiger, Lauren Ulsh, Berkeley Limketkai, David Goldenberg, Philip Okafor, Irene Sonu, Neil Stollman & Leila Neshatian

doi : 10.1007/s10620-022-07761-9

Fecal microbiota transplantation (FMT) is a highly effective treatment for recurrent Clostridioides difficile infection (CDI). However, 10–20% of patients still fail to recover following FMT. There is a need to understand why these failures occur and if there are modifiable factors that can be addressed by clinicians performing FMT.

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Video-Based Deep Learning to Detect Dyssynergic Defecation with 3D High-Definition Anorectal Manometry

Joshua J. Levy, Christopher M. Navas, Joan A. Chandra, Brock C. Christensen, Louis J. Vaickus, Michael Curley, William D. Chey, Jason R. Baker & Eric D. Shah

doi : 10.1007/s10620-022-07759-3

We developed a deep learning algorithm to evaluate defecatory patterns to identify dyssynergic defecation using 3-dimensional high definition anal manometry (3D-HDAM).

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Evaluation of 13,466 Fecal Immunochemical Tests in Patients Attending Primary Care for High- and Low-Risk Gastrointestinal Symptoms of Colorectal Cancer

Rigers Cama, Neel Kapoor, Philip Sawyer, Bharat Patel & Jonathan Landy

doi : 10.1007/s10620-022-07754-8

Quantitative fecal immunochemical tests (FIT) were recommended by NICE for patients in primary care presenting with low-risk symptoms of colorectal cancer (CRC). FIT is more accurate in the detection of CRC than symptom criteria.

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Standard Endoscopic Mucosal Resection vs Precutting Endoscopic Mucosal Resection Using Novel Disk-Tip Snare for Colorectal Lesions

Naohisa Yoshida, Ken Inoue, Hikaru Hashimoto, Reo Kobayashi, Yuri Tomita, Satoshi Sugino, Ryohei Hirose, Osamu Dohi, Yukiko Morinaga, Yutaka Inada, Takaaki Murakami & Yoshito Itoh

doi : 10.1007/s10620-023-07833-4

SOUTEN (KANEKA Co., Tokyo, Japan) is a unique snare with a disk tip. We analyzed the efficacy of precutting endoscopic mucosal resection with SOUTEN (PEMR-S) for colorectal lesions.

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Risk Factors Related to Polyp Miss Rate of Short-Term Repeated Colonoscopy

Wenxi Jiang, Linying Xin, Shefeng Zhu, Zhaoxue Liu, Jiali Wu, Feng Ji, Chaohui Yu & Zhe Shen

doi : 10.1007/s10620-023-07848-x

Colonoscopy is regarded as the gold standard for colorectal cancer screening and surveillance. However, previous studies have reported large numbers of polyps were missed during routine colonoscopy.

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Prognostic Benefit of Additional Treatment After Endoscopic Submucosal Dissection for Esophageal Squamous Cell Carcinoma

So Takahashi, Waku Hatta, Kenta Watanabe, Tomoyuki Koike, Tomohiro Shimada, Takuto Hikichi, Yosuke Toya, Ippei Tanaka, Yusuke Onozato, Koichi Hamada, Daisuke Fukushi, Ko Watanabe, Shoichi Kayaba, Hirotaka Ito, Tatsuya Mikami, Tomoyuki Oikawa, Yasushi Takahashi, Yutaka Kondo, Tetsuro Yoshimura, Takeharu Shiroki, Ko Nagino, Norihiro Hanabata, Akira Funakubo, Dai Hirasawa, …Katsunori Iijima

doi : 10.1007/s10620-022-07746-8

Although additional treatment is considered for patients with esophageal squamous cell carcinoma (ESCC) invading into the muscularis mucosa (pT1a-MM) or submucosa (pT1b-SM) after endoscopic submucosal dissection (ESD), the actual benefits of this method remain to be elucidated.

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Low Detection Rates of Bile Duct Stones During Endoscopic Treatment for Highly Suspected Bile Duct Stones with No Imaging Evidence of Stones

Hirokazu Saito, Hajime Iwasaki, Hisashi Itoshima, Yoshihiro Kadono, Takashi Shono, Kentaro Kamikawa, Atsushi Urata, Jiro Nasu, Masayoshi Uehara, Ikuo Matsushita, Tatsuyuki Kakuma & Shuji Tada

doi : 10.1007/s10620-022-07773-5

The revised American Society for Gastrointestinal Endoscopy (ASGE) guideline 2019 provides the high-risk criteria for suspected common bile duct stones (CBDSs).

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A New Risk Score to Predict Intensive Care Unit Admission for Patients with Acute Pancreatitis 48 Hours After Admission: Multicenter Study

Lei Yuan, Lei Shen, Mengyao Ji, Xinyu Wen, Shuo Wang, Pingxiao Huang, Yong Li & Jun Xu

doi : 10.1007/s10620-022-07768-2

The objective of this study was to develop and validate an easy-to-use risk score (APRS) to predict which patients with acute pancreatitis (AP) will need intensive care unit (ICU) treatment within 48 h post-hospitalization on the basis of the ubiquitously available clinical records.

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Dynamics of Serum Procalcitonin Can Predict Outcome in Patients of Infected Pancreatic Necrosis: A Prospective Analysis

Jayanta Samanta, Jahnvi Dhar, Chhagan Lal Birda, Pankaj Gupta, Thakur Deen Yadav, Vikas Gupta, Saroj Kant Sinha & Rakesh Kochhar

doi : 10.1007/s10620-022-07758-4

Timely intervention can alter outcome in patients of infected pancreatic necrosis (IPN) but lacks adequate biomarker. Role of serum procalcitonin (PCT) in the management of IPN is understudied, and hence, this study was planned.

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Endoscopic Ultrasound-Guided Hepaticogastrostomy with Antegrade Stenting Without Dilation Device Application for Malignant Distal Biliary Obstruction in Pancreatic Cancer

Tadahisa Inoue, Rena Kitano, Mayu Ibusuki, Kazumasa Sakamoto, Satoshi Kimoto, Yuji Kobayashi, Yoshio Sumida, Yukiomi Nakade, Kiyoaki Ito & Masashi Yoneda

doi : 10.1007/s10620-022-07749-5

Endoscopic ultrasound-guided hepaticogastrostomy with antegrade stenting (EUS-HGAS) is a promising therapeutic option for malignant distal biliary obstruction (MDBO) in the event of transpapillary approach failure. Eliminating the fistula dilation step may further decrease the incidence of adverse events (AE) and simplify the procedure.

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Clinical and Liver Biochemistry Phenotypes, and Outcome in 133 Patients with Anti-seizure Drug-Induced Liver Injury

Harshad Devarbhavi, Aarthi Sridhar, Sunu Sara Kurien, Vinod Gowda, Ksheetij Kothari, Mallikarjun Patil & Rajvir Singh

doi : 10.1007/s10620-022-07777-1

Anti-seizure drugs that cause idiosyncratic drug-induced liver injury (DILI) are an important cause of morbidity and mortality in individuals exposed to these drugs. The clinical and demographic characteristics, the liver injury pattern, the outcome, and the agents responsible for hepatotoxicity have not been thoroughly studied. We investigated the aforementioned characteristics in a large cohort of DILI registry patients.

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Prevalence of Undiagnosed Acute Hepatic Porphyria in Cyclic Vomiting Syndrome and Overlap in Clinical Symptoms

Shanna Cheng, Elliot Yu, Zhuping Garacci, Angelika L. Erwin & Thangam Venkatesan

doi : 10.1007/s10620-022-07756-6

Acute hepatic porphyria (AHP) presents with nausea and vomiting and can mimic cyclic vomiting syndrome (CVS). The prevalence of AHP in CVS and overlap in clinical symptomatology is not known. We thus sought to determine the prevalence of pathogenic variants for AHP and characterize symptom overlap between CVS and AHP.

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Improved Liver Function After Sustained Virologic Response Enhanced Prognosis in Hepatitis C with Compensated Advanced Liver Fibrosis

Yuki Tahata, Ryotaro Sakamori, Ryoko Yamada, Takahiro Kodama, Hayato Hikita, Hideki Hagiwara, Masahide Oshita, Yasuharu Imai, Naoki Hiramatsu, Eiji Mita, Akira Kaneko, Masanori Miyazaki, Kazuyoshi Ohkawa, Taizo Hijioka, Hiroyuki Fukui, Toshifumi Ito, Keiji Yamamoto, Yoshinori Doi, Yuichi Yoshida, Yukinori Yamada, Takayuki Yakushijin, Tomohide Tatsumi, Tetsuo Takehara & Osaka Liver Forum

doi : 10.1007/s10620-022-07629-y

Liver function can be improved in patients with chronic hepatitis C virus (HCV) infection who achieved sustained virologic response (SVR) with direct-acting antiviral (DAA) treatment. However, to our knowledge, the impact of liver function improvement after SVR on prognosis has not been investigated.

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High-Intensity Interval Training is Safe, Feasible and Efficacious in Nonalcoholic Steatohepatitis: A Randomized Controlled Trial

Shelley E. Keating, Ilaria Croci, Matthew P. Wallen, Emily R. Cox, Moe Thuzar, Uyen Pham, Gregore I. Mielke, Jeff S. Coombes, Graeme A. Macdonald & Ingrid J. Hickman

doi : 10.1007/s10620-022-07779-z

High-Intensity Interval Training (HIIT) involves bursts of high-intensity exercise interspersed with lower-intensity exercise recovery. HIIT may benefit cardiometabolic health in people with nonalcoholic steatohepatitis (NASH).

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Impact of Bacteria Types on the Clinical Outcomes of Spontaneous Bacterial Peritonitis

Cameron Furey, Selena Zhou, Joo Hye Park, Andrew Foong, Aneesa Chowdhury, Lillian Dawit, Vivian Lee, Maria Vergara-Lluri, Rosemary She, Jeffrey Kahn, Jennifer L. Dodge & Takeshi Saito

doi : 10.1007/s10620-023-07867-8

Cirrhotic patients presenting with spontaneous bacterial peritonitis (SBP) have elevated risk of short-term mortality. While high Model for End-Stage Liver Disease-Sodium score (MELD-Na) and ascites culture yielding multi-drug resistance (MDR) bacteria are well established risk factors for further aggravating mortality, the impact of individual, causative microorganisms and their respective pathogenesis have not been previously investigated.

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Assessment of the Performance of Non-invasive Criteria for the Evaluation of Clinically Significant Portal Hypertension in Patients with Compensated Advanced Chronic Liver Disease

Ankur Jindal, Samagra Agarwal, Sanchit Sharma, Manoj Kumar, Anoop Saraya & Shiv Kumar Sarin

doi : 10.1007/s10620-022-07778-0

Assessment of clinically significant portal hypertension (CSPH) non-invasively using a combination of liver stiffness measurement (LSM) and platelet counts is proposed as an alternative to hepatic venous pressure gradient (HVPG) estimation. Utility of these criteria in compensated advanced chronic liver disease (cACLD) patients of different etiologies including nonalcoholic steatohepatitis (NASH) with BMI  >  30 kg/m2 was studied in a large cohort.

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High Uptake of Three COVID-19 Vaccine Doses Among Liver Transplant Recipients

Trevor L. Schell, Miguel A. Mailig, Mazen Almasry, Sarah Lazarus, Luke J. Richard, Katharine Tippins, Jennifer Weiss, Mary S. Hayney & Freddy Caldera

doi : 10.1007/s10620-023-07902-8

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HBV/HCV Infection Was Not Significantly Independently Associated with COVID-19 Severity: A Meta-Analysis of Confounding Variables-Adjusted Data

Jie Xu, Yujia Wang, Huifen Feng, Fang Liu & Haiyan Yang

doi : 10.1007/s10620-022-07799-9

خرید پکیج و مشاهده آنلاین مقاله


Retraction Note: Rosiglitazone Inhibits Activation of Hepatic Stellate Cells via Up-Regulating Micro-RNA-124-3p to Alleviate Hepatic Fibrosis

Shao-ce Zhi, Shi-zuan Chen, Yan-yan Li, Jun-jian Li, Yi-hu Zheng & Fu-xiang Yu

doi : 10.1007/s10620-023-07926-0

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