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Effect of Regular, Low-Dose, Extended-release Morphine on Chronic Breathlessness in Chronic Obstructive Pulmonary DiseaseThe BEAMS Randomized Clinical Trial
Magnus Ekström, MD, PhD1,2; Diana Ferreira, MD, PhD3; Sungwon Chang, PhD2; Sandra Louw, BSc4; Miriam J. Johnson, MD, MBChB5; Danny J. Eckert, PhD6; Belinda Fazekas, GDip2; Katherine J. Clark, PhD7,8; Meera R. Agar, PhD2; David C. Currow, MPH, PhD3,9; for the Australian National Palliative Care Clinical Studies Collaborative
doi : 10.1001/jama.2022.20206
November 22/29, 2022, Vol 328, No. 20, Pages 1993-2078
Importance Chronic breathlessness is common in people with chronic obstructive pulmonary disease (COPD). Regular, low-dose, extended-release morphine may relieve breathlessness, but evidence about its efficacy and dosing is needed.
Treatment Time and In-Hospital Mortality Among Patients With ST-Segment Elevation Myocardial Infarction, 2018-2021
James G. Jollis, MD1,2; Christopher B. Granger, MD2; Jessica K. Zègre-Hemsey, RN, PhD3; Timothy D. Henry, MD1; Abhinav Goyal, MD, MHS4; Jacqueline E. Tamis-Holland, MD5; Mayme Lou Roettig, RN, MSN2; Murtuza J. Ali, MD, MBA6; William J. French, MD7; Ram Poudel, MS, MPH8; Juan Zhao, PhD8; R. Harper Stone, MD9; Alice K. Jacobs, MD10
doi : 10.1001/jama.2022.20149
Importance Recognizing the association between timely treatment and less myocardial injury for patients with ST-segment elevation myocardial infarction (STEMI), US national guidelines recommend specific treatment-time goals.
Estimated Travel Time and Spatial Access to Abortion Facilities in the US Before and After the Dobbs v Jackson Women’s Health Decision
Benjamin Rader, MPH1,2; Ushma D. Upadhyay, PhD, MPH3; Neil K. R. Sehgal, BA1,4; Ben Y. Reis, PhD5,6; John S. Brownstein, PhD1,6; Yulin Hswen, ScD7,8
doi : 10.1001/jama.2022.20424
Importance Abortion facility closures resulted in a substantial decrease in access to abortion care in the US.
Association of Texas’ 2021 Ban on Abortion in Early Pregnancy With the Number of Facility-Based Abortions in Texas and Surrounding States
Kari White, PhD, MPH1,2; Gracia Sierra, PhD, MS2,3; Klaira Lerma, MPH2,3; Anitra Beasley, MD, MPH2,4; Lisa G. Hofler, MD, MPH, MBA5; Kristina Tocce, MD, MPH6; Vinita Goyal, MD, MPH2,3; Tony Ogburn, MD2,7; Joseph E. Potter, PhD2,3; Samuel L. Dickman, MD8
doi : 10.1001/jama.2022.20423
Reported Awareness and Adoption of 2021 Estimated Glomerular Filtration Rate Equations Among US Clinical Laboratories, March 2022
Jonathan R. Genzen, MD, PhD1; Rhona J. Souers, MS2; Lauren N. Pearson, DO, MPH1; David M. Manthei, MD, PhD3; Allison B. Chambliss, PhD4; Zahra Shajani-Yi, PhD5; W. Greg Miller, PhD6
doi : 10.1001/jama.2022.15404
Extended Follow-up of Microbiome Therapeutic SER-109 Through 24 Weeks for Recurrent Clostridioides difficile Infection in a Randomized Clinical Trial
Stuart H. Cohen, MD1; Thomas J. Louie, MD2; Matthew Sims, MD, PhD3; Elaine E. L. Wang, MD4; Asli Memisoglu, ScD4; Barbara H. McGovern, MD4; Lisa von Moltke, MD4
doi : 10.1001/jama.2022.16476
Human Monkeypox Virus Infection in the Immediate Period After Receiving Modified Vaccinia Ankara Vaccine
Aniruddha Hazra, MD1; Laura Rusie, ScM1; Trevor Hedberg, MPH, PA-C1; John A. Schneider, MD, MPH1
doi : 10.1001/jama.2022.18320
Closing the Loophole on Hemp-Derived Cannabis ProductsA Public Health Priority
Alyssa F. Harlow, PhD, MPH1; Adam M. Leventhal, PhD1; Jessica L. Barrington-Trimis, PhD1
doi : 10.1001/jama.2022.20620
The Tobacco Industry and Harm Reduction
Howard K. Koh, MD, MPH1; Michael C. Fiore, MD, MPH, MBA2
doi : 10.1001/jama.2022.20679
Implications of Dobbs for the (Re)Criminalization of Intimacy Among LGBTQ Individuals
Joanne D. Rosen, JD, MA1; Chris Beyrer, MD, MPH2
doi : 10.1001/jama.2022.20609
Dyspnea—When a Sensation Becomes a Symptom
Richard M. Schwartzstein, MD1,2
doi : 10.1001/jama.2022.19248
Time to Treatment in ST-Segment Elevation Myocardial InfarctionIdentifying Dangerous Delays or Diminishing Returns?
Andrew S. Oseran, MD, MBA1,2; Robert W. Yeh, MD, MSc1
doi : 10.1001/jama.2022.19441
The International Code of Medical Ethics of the World Medical Association
Ramin Walter Parsa-Parsi, MD, MPH1,2
doi : 10.1001/jama.2022.19697
Diagnosis and Treatment of Infertility in Men
Joshua A. Halpern, ME, MS1; Andrew M. Davis, MD, MPH2; Robert E. Brannigan, MD1
doi : 10.1001/jama.2022.19294
Intermittent Chest Pain in a 46-Year-Old Patient
Carlos Plappert, MD1,2; Mohammad Sherif, MD1,2; Christian Oeing, MD1,2
doi : 10.1001/jama.2022.19443
After the First Pig-to-Human Heart Transplant, Scientists Look to the Future of Cardiac Xenotransplantation
Jyoti Madhusoodanan
doi : 10.1001/jama.2022.15434
CDC Report: Urgent Need to Address Teens’ Adverse Experiences During Pandemic
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2022.18488
Targeted Flu Vaccination Campaigns Needed for Certain Racial and Ethnic Groups
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2022.18487
Financial Vouchers Led to Higher Smoking Abstinence During Pregnancy
Anita Slomski
doi : 10.1001/jama.2022.18484
Intranasal COVID-19 Vaccine Disappointing in First-in-Human Trial
Anita Slomski
doi : 10.1001/jama.2022.18485
Shorter Duration of Antibiotics Noninferior for Lyme Disease
Anita Slomski
doi : 10.1001/jama.2022.21305
White House Fixes “Family Glitch� in Health Insurance Subsidies
Melissa Suran, PhD, MSJ
doi : 10.1001/jama.2022.18480
New Guidance for Reducing Health Care Organizations’ Carbon Emissions
Melissa Suran, PhD, MSJ
doi : 10.1001/jama.2022.18481
GAO Calls for Nationwide Analysis of “Forever Chemicals�
Melissa Suran, PhD, MSJ
doi : 10.1001/jama.2022.18482
Use of Albumin Solution in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass
Yongqi Zhou, MD1; Tao Zhu, MD, PhD1; Chan Chen, MD, PhD1
doi : 10.1001/jama.2022.17488
Use of Albumin Solution in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass—Reply
Eero Pesonen, MD, PhD1; Tatu Juvonen, MD, PhD2; Ville Pettilä, MD, PhD3
doi : 10.1001/jama.2022.17491
US Tracking System for Nonfatal Drug Overdoses
Steven M. Marcus, MD1
doi : 10.1001/jama.2022.17494
US Tracking System for Nonfatal Drug Overdoses—Reply
Rahul Gupta, MD, MPH, MBA1; David R. Holtgrave, PhD1
doi : 10.1001/jama.2022.17497
Fluid Bolus Administration and Cardiovascular Collapse in Critically Ill Patients Undergoing Tracheal Intubation
Ambika Tejpal, MD1; Matteo Parotto, MD, PhD2; Michael C. Sklar, MD3
doi : 10.1001/jama.2022.17502
Fluid Bolus Administration and Cardiovascular Collapse in Critically Ill Patients Undergoing Tracheal Intubation
Ward H. van der Ven, MD1; Alexander P. J. Vlaar, MD, PhD, MBA2; Denise P. Veelo, MD, PhD1
doi : 10.1001/jama.2022.17505
Fluid Bolus Administration and Cardiovascular Collapse in Critically Ill Patients Undergoing Tracheal Intubation
Nirvik Pal, MD1; Miklos D. Kertai, MD, PhD2; John Butterworth, MD1
doi : 10.1001/jama.2022.17499
Fluid Bolus Administration and Cardiovascular Collapse in Critically Ill Patients Undergoing Tracheal Intubation—Reply
Derek W. Russell, MD1; Jonathan D. Casey, MD, MSc2; Matthew W. Semler, MD, MSc2
doi : 10.1001/jama.2022.17508
