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Acute Ischemic Stroke: Don't Skip the Thrombolytics Before Transfer for Thrombectomy.
Cronin, Carolyn A. MD, PhD
doi : 10.1212/WNL.0000000000206841
Volume 100(14) pgs. 643-688,e1436-e1528 April 4, 2023
Adverse Pregnancy Outcomes and Migraine: What We Know and What We Can Do.
VanderPluym, Juliana H. MD
IV Thrombolysis Initiated Before Transfer for Endovascular Stroke Thrombectomy: A Systematic Review and Meta-analysis.
Katsanos, Aristeidis H. MD; Sarraj, Amrou MD; Froehler, Michael MD; Purrucker, Jan MD; Goyal, Nitin MD; Regenhardt, Robert William MD, PhD; Palaiodimou, Lina MD; Mueller-Kronast, Nils H. MD; Lemmens, Robin MD; Schellinger, Peter D. MD; Sacco, Simona MD; Turc, Guillaume MD; Alexandrov, Andrei V. MD; Tsivgoulis, Georgios MD, PhD
doi : 10.1212/WNL.0000000000206784
The role of IV thrombolysis (IVT) in patients with large vessel occlusions (LVOs) administered before transfer from a primary stroke center (PSC) to a comprehensive stroke center (CSC) is questioned.
Age-Related Differences in the Role of Risk Factors for Ischemic Stroke.
Howard, George DrPH; Banach, Maciej MD, PhD; Kissela, Brett MD, MS; Cushman, Mary MD, MSc; Muntner, Paul PhD; Judd, Suzanne E. PhD; Howard, Virginia J. PhD
doi : 10.1212/WNL.0000000000206837
Reports assessing the association of stroke risk factors with incident stroke have generally assumed a uniform magnitude of associations across the age spectrum, an assumption we assess in this report
Premature Cardiovascular Disease and Brain Health in Midlife: The CARDIA Study.
Jiang, Xiaqing MD, PhD, MPH; Lewis, Cora E. MD, MSPH; Allen, Norrina B. PhD, MPH; Sidney, Stephen MD, MPH; Yaffe, Kristine MD
doi : 10.1212/WNL.0000000000206825
To understand the role of premature (defined as <= 60 years) cardiovascular disease (CVD) in brain health earlier in life, we examined the associations of premature CVD with midlife cognition and white matter health.
Prepregnancy Migraine, Migraine Phenotype, and Risk of Adverse Pregnancy Outcomes.
Purdue-Smithe, Alexandra C. PhD; Stuart, Jennifer J. ScD; Farland, Leslie V. ScD; Kang, Jae H. ScD; Harriott, Andrea M. MD, PhD; Rich-Edwards, Janet W. ScD; Rexrode, Kathryn MD, MPH
doi : 10.1212/WNL.0000000000206831
Migraine is a highly prevalent neurovascular disorder among reproductive-aged women. Whether migraine history and migraine phenotype might serve as clinically useful markers of obstetric risk is not clear.
Estrogen Receptor Genes, Cognitive Decline, and Alzheimer Disease.
Oveisgharan, Shahram MD; Yang, Jingyun PhD; Yu, Lei PhD; Burba, Dominika MS; Bang, Woojeong MS; Tasaki, Shinya PhD; Grodstein, Fran PhD; Wang, Yanling PhD; Zhao, Jinying PhD; De Jager, Philip Lawrence PhD; Schneider, Julie A. MD; Bennett, David A. MD
doi : 10.1212/WNL.0000000000206833
Lifetime risk of Alzheimer disease (AD) dementia is twofold higher in women compared with men, and low estrogen levels in postmenopause have been suggested as a possible contributor.
Effectiveness of Antiseizure Medication Triple Therapy in Patients With Glioma With Refractory Epilepsy: An Observational Cohort Study.
van der Meer, Pim B. MSc; Dirven, Linda PhD; Fiocco, Marta PhD; Vos, Maaike J. PhD; Kouwenhoven, Mathilde C.M. PhD; van den Bent, Martin J. PhD; Taphoorn, Martin J.B. PhD; Koekkoek, Johan A.F. PhD
doi : 10.1212/WNL.0000000000206852
Approximately 10% of patients with glioma with epilepsy need antiseizure medication (ASM) triple therapy due to refractory epilepsy.
Natural Course and Prognosis of Primary Spinal Glioblastoma: A Nationwide Study.
Amelot, Aymeric MD, PhD; Terrier, Louis-Marie MD, PhD; Mathon, Bertrand MD; Joubert, Christophe MD; Picart, Thiebaud MD, PhD; Jecko, Vincent MD; Bauchet, Luc MD, PhD; Bernard, Florian MD, PhD; Castel, Xavier MD, PhD; Chenin, Louis MD; Cook, Ann-Rose MD; Emery, Evelyne MD, PhD; Figarella-Branger, Dominique MD, PhD; Gauchotte, Guillaume MD, PhD; Graillon, Thomas MD, PhD; Jouvet, Anne MD, PhD; Kalamarides, Michel MD, PhD; Knafo, Steven MD, PhD; Lazard, Arnaud MD; Lubrano, Vincent MD, PhD; Mokhtari, Karima MD, PhD; Rigau, Valerie MD, PhD; Roualdes, Vincent MD, PhD; Rousseau, Audrey MD, PhD; Seizeur, Romuald MD, PhD; Uro-Coste, Emmanuelle MD, PhD; Voirin, Jimmy MD, PhD; Metellus, Philippe MD, PhD; Pallud, Johan MD, PhD; Zemmoura, Ilyess MD, PhD; and the Medullary Glioblastoma study group
doi : 10.1212/WNL.0000000000206834
Primary spinal glioblastoma (PsGBM) is extremely rare. The dramatic neurologic deterioration and unresectability of PsGBM makes it a particularly disabling malignant neoplasm.
Characteristics and Outcomes of Athletes With Slow Recovery From Sports-Related Concussion: A CARE Consortium Study.
McAllister, Thomas W. MD; Broglio, Steven P. PhD; Katz, Barry P. PhD; Perkins, Susan M. PhD; LaPradd, Michelle MS; Zhou, Wenxian MS; McCrea, Michael A. PhD; on behalf of Concussion Assessment, Research and Education (CARE) Consortium
doi : 10.1212/WNL.0000000000206853
Some athletes experience a slow recovery after sport-related concussion (SRC). There is little agreement on what constitutes slow recovery, however, and minimal data on the prevalence, predictors, or prognosis for this group.
Long-term Safety, Dose Stability, and Efficacy of Opioids for Patients With Restless Legs Syndrome in the National RLS Opioid Registry.
Winkelman, John Weyl MD, PhD; Wipper, Benjamin BA; Zackon, Jordana BA
doi : 10.1212/WNL.0000000000206855
Restless legs syndrome (RLS) is a sensory-motor neurologic disorder. Low-dose opioids are prescribed for patients with refractory or augmented RLS.
Biological Sex Differences in Risk Factors and Outcomes Among Hospitalized Adults With Stroke in Lusaka, Zambia.
Nutakki, Aparna BA; Chomba, Mashina MBChB, MMed; Chishimba, Lorraine Chishimba MMED; Zimba, Stanley MMED, STP; Gottesman, Rebecca F. MD, PhD; Bahouth, Mona N. MD, PhD; Saylor, Deanna R. MD, MHS
doi : 10.1212/WNL.0000000000201696
We investigated sex differences in clinical characteristics and outcomes among hospitalized adults with stroke in Zambia. Methods: We retrospectively collected information for 324 consecutively hospitalized adults with stroke on the neurology service at the University Teaching Hospital in Lusaka, Zambia, between October 2018 and March 2019.
Complicated Monkeypox Infection in a Patient With Multiple Sclerosis and Fingolimod Treatment.
Muller-Jensen, Leonie MD *; Kriedemann, Helene MD *; Anvari, Kerstin MD; Huehnchen, Petra MD; Siffrin, Volker MD
NEXMIF Epilepsy: An Alternative Cause of Progressive Myoclonus.
Chorny, Lauren E. DO; Nordli, Douglas R. III MD; Galan, Fernando MD
Clinical Reasoning: A 23-Year-Old Man With Progressive Asymmetric Weakness and Numbness.
Kaplan, Emma H. MD *; Torabian, Kaveh MS *; Edwards, Camille V. MD; Kaku, Michelle C. MD; Anand, Pria MD; Lau, K. H. Vincent MD
doi : 10.1212/WNL.0000000000206773
AB We report a case of a 23-year-old man who presented with progressive asymmetric weakness and numbness in his distal extremities over 4 months, with initial symptoms starting days after a coronavirus 2019 (COVID-19) vaccine booster.
Teaching NeuroImage: Ictal Pouting Associated With Focal Cortical Dysplasia and Frontal Seizures on Stereotactic Depth Electrode EEG.
Marques, Paula MD *; Wennberg, Richard MD *; Andrade, Danielle M. MD, MSc *
Teaching Video NeuroImage: Reverse Ocular Bobbing as a Presenting Feature of Brainstem Cavernoma.
Singh, Kavindra MBBS, MS, MCh; Salunke, Pravin MBBS, MS, MCh
Editors' Note: Long-term Neurologic Safety in Patients With B-Cell Lymphoma Treated With Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy.
Lewis, Ariane MD; Galetta, Steven MD
Reader Response: Long-term Neurologic Safety in Patients With B-Cell Lymphoma Treated With Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy.
Karschnia, Philipp; Rejeski, Kaj; Subklewe, Marion; von Baumgarten, Louisa
Reader Response: Long-term Neurologic Safety in Patients With B-Cell Lymphoma Treated With Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy.
Tan, Brendan Jen-Wei; Chan, Ling-Ling; Tan, Eng-King
