دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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It is time to define cognitive phenotypes in multiple sclerosis
Ermelinda De Meo and Emilio Portaccio
doi : 10.1177/13524585221141263
Volume 29 Issue 4-5, April 2023
Association between infections, the microbiome, vaccination, and neuromyelitis optica spectrum disorder
Edgar Carnero Contentti and Jorge Correale
doi : 10.1177/13524585221113272
Neuromyelitis optica spectrum disorder (NMOSD) is a devastating antibody-mediated condition of the central nervous system. As in other autoimmune diseases, there is considerable evidence to suggest that NMOSD arises from complex interactions between genetic susceptibility and environmental factors
A journey with no roadmap�The need for validated criteria of the MS prodrome
Sharon Roman
doi : 10.1177/13524585221135883
A growing body of compelling evidence has emerged to validate a set of signs and symptoms that indicates the onset of disease before more typical signs and symptoms present to fulfill a diagnosis of MS.
Rare and low-frequency coding genetic variants contribute to pediatric-onset multiple sclerosis
Mary K Horton , Joan E Shim, Amelia Wallace , Jennifer S Graves , Gregory Aaen, Benjamin Greenberg , Soe Mar, Yolanda Wheeler, Bianca Weinstock-Guttman , Amy Waldman, Teri Schreiner , Moses Rodriguez, Jan-Mendelt Tillema, Tanuja Chitnis , Lauren Krupp, T Charles Casper, Mary Rensel , Janace Hart, Hong L Quach, Diana L Quach, Catherine Schaefer, Emmanuelle Waubant * and Lisa F Barcellos*; The Network of Pediatric Multiple Sclerosis Centers
doi : 10.1177/13524585221150736
Rare genetic variants are emerging as important contributors to the heritability of multiple sclerosis (MS). Whether rare variants also contribute to pediatric-onset multiple sclerosis (POMS) is unknown.
Genetic regulation of IL-8 influences disease presentation of multiple sclerosis
Ettore Dolcetti, Antonio Bruno, Federica Azzolini, Luana Gilio, Luigi Pavone, Ennio Iezzi, Giovanni Galifi, Stefano Gambardella, Rosangela Ferese, Fabio Buttari, Francesca De Vito, Paola Colantuono, Roberto Furlan , Annamaria Finardi, Alessandra Musella, Georgia Mandolesi, Diego Centonze and Mario Stampanoni Bassi
doi : 10.1177/13524585231155049
Individual genetic variability may influence the course of multiple sclerosis (MS). The interleukin (IL)-8C>T rs2227306 single nucleotide polymorphism (SNP) regulates IL-8 activity in other clinical conditions; however, its role in MS has never been investigated.
A national case–control study investigating demographic and environmental factors associated with NMOSD
Dalia L Rotstein , Christina Wolfson, Robert Carruthers , Mark S Freedman, Sarah A Morrow, Liesly Lee, Jodie M Burton, Rosane Nisenbaum, Andrea Konig, Sandra Magalhaes and Ruth Ann Marrie
doi : 10.1177/13524585231151953
Risk factors for aquaporin-4 (AQP4+) antibody neuromyelitis optica spectrum disorder (NMOSD) are not well-established.
Epidemiological and clinical characteristics of myelin oligodendrocyte glycoprotein antibody-associated disease in a nationwide survey
Masashi Nakamura , Ryo Ogawa, Juichi Fujimori, Akiyuki Uzawa, Yasunori Sato, Kengo Nagashima , Nagato Kuriyama, Satoshi Kuwabara and Ichiro Nakashima
doi : 10.1177/13524585231156736
To our knowledge, no nationwide epidemiological study of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) has been conducted.
Choroid plexus volume is enlarged in clinically isolated syndrome patients with optic neuritis
Samuel Klistorner, Anneke Van der Walt , Michael H Barnett , Helmut Butzkueven, Scott Kolbe , John Parratt, Con Yiannikas and Alexander Klistorner
doi : 10.1177/13524585231157206
We investigated choroid plexus (CP) volume in patients presenting with optic neuritis (ON) as a clinically isolated syndrome (CIS), compared to a cohort with established relapsing–remitting multiple sclerosis (RRMS) and healthy controls (HCs).
Cerebrospinal fluid–related tissue damage in multiple sclerosis patients with iron rim lesions
Matthias Wittayer, Claudia E Weber, Maximilian Kittel, Michael Platten, Lucas Schirmer , Hayrettin Tumani, Achim Gass* and Philipp Eisele
doi : 10.1177/13524585231155639
In multiple sclerosis (MS), iron rim lesions (IRLs) are associated with pronounced tissue damage, higher disease severity and have been suggested as an imaging marker of chronic active inflammation behind the blood–brain barrier indicating progression. Furthermore, chronic intrathecal compartmentalized inflammation has been suggested to be a mediator of a cerebrospinal fluid (CSF)–related tissue damage.
Performance of McDonald 2017 multiple sclerosis diagnostic criteria and evaluation of genetic ancestry in patients with a first demyelinating event in Argentina
Mariano Marrodan , Maria Agustina Piedrabuena, Maria Ines Gaitan, Marcela P Fiol, Maria Celica Ysrraelit, Edgar Carnero Contentti , Pablo Adrian Lopez, Veronica Peuchot and Jorge Correale
doi : 10.1177/13524585231157276
Information on performance of multiple sclerosis (MS) diagnostic criteria is scarce for populations from Latin America, Asia, or the Caribbean.
The impact of relapse definition and measures of durability on MS clinical trial outcomes
Sammita Satyanarayan , Gary Cutter , Stephen Krieger, Stacey Cofield, Jerry S Wolinsky and Fred Lublin
doi : 10.1177/13524585231157211
Definitions of trial measures are consequential to accurately capturing outcomes and cross-trial comparability, particularly for derivative measures.
Characteristics of pediatric patients with multiple sclerosis and related disorders infected with SARS-CoV-2
Teri Schreiner , Molly Wilson-Murphy, Jan Mendelt-Tillema, Michael Waltz, Rachel Codden, Leslie Benson, Mark Gorman, Manu Goyal, Lauren Krupp , Tim Lotze, Soe Mar, Jayne Ness, Mary Rensel , Shelly Roalstad, Moses Rodriguez, John Rose, Nikita Shukla, Emmanuelle Waubant, Yolanda Wheeler, T Charles Casper and Tanuja Chitnis
doi : 10.1177/13524585231151948
Pediatric patients with multiple sclerosis (POMS) and related disorders, clinically isolated syndrome (CIS), myelin oligodendrocyte glycoprotein antibody disorder (MOGAD), and neuromyelitis optica spectrum disorder (NMOSD), are commonly treated with immunosuppressants. Understanding the impact of SARS-CoV-2 infection in patients may inform treatment decisions.
Safety of COVID-19 vaccines in multiple sclerosis: A systematic review and meta-analysis
Maria-Ioanna Stefanou*, Lina Palaiodimou* , Aikaterini Theodorou, Maria Veatriki Christodoulou , John S Tzartos, Dimitrios Tzanetakos, Dimitrios Kitsos, Maria Chondrogianni, Vasiliki Zouvelou, Efthimios Dardiotis, Elias Tzavellas, Ekaterini Syrigou, Vassiliki Benetou, George P Paraskevas, Sotirios Tsiodras, Georgios Tsivgoulis †and Sotirios Giannopoulos
doi : 10.1177/13524585221150881
Data are sparse regarding the safety of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in patients with multiple sclerosis (MS).
Acute central nervous system inflammation following COVID-19 vaccination: An observational cohort study
Sydney Lee , Alexandra Muccilli, Raphael Schneider, Daniel Selchen and Kristen M Krysko
doi : 10.1177/13524585231154780
Reports suggest a potential association between coronavirus disease 2019 (COVID-19) vaccines and acute central nervous system (CNS) inflammation.
Personalized monitoring of ambulatory function with a smartphone 2-minute walk test in multiple sclerosis
Ka-Hoo Lam , Ioan Gabriel Bucur, Pim van Oirschot, Frank de Graaf, Eva Strijbis , Bernard Uitdehaag, Tom Heskes, Joep Killestein and Vincent de Groot
doi : 10.1177/13524585231152433
Remote smartphone-based 2-minute walking tests (s2MWTs) allow frequent and potentially sensitive measurements of ambulatory function.
A proposed new taxonomy of cognitive phenotypes in multiple sclerosis: The International Classification of Cognitive Disorders in MS (IC-CoDiMS)
Laura M Hancock, Rachel Galioto, Alexey Samsonov, Robyn M Busch, Bruce Hermann and Jordi A Matias-Guiu
doi : 10.1177/13524585221127941
Characterization of cognitive impairment (CI) in multiple sclerosis into distinct phenotypes holds promise for individualized treatments and biomarker exploration.
Comparative effectiveness of natalizumab on cognition in multiple sclerosis: A cohort study
Ali Manouchehrinia , Hanna Larsson, Mohammad Ehsanul Karim , Jan Lycke , Tomas Olsson * and Ingrid Kockum
doi : 10.1177/13524585231153992
Cognitive impairment occurs in 40%–70% of persons with multiple sclerosis (MS).
Should trigeminal neuralgia be considered a clinically isolated syndrome?
Sarasa Tohyama , Jiwon Oh, Makenna Timm, Joshua C Cheng, Aisha Halawani , David J Mikulis, Andrew J Solomon * and Mojgan Hodaie
doi : 10.1177/13524585221149886
The association between trigeminal neuralgia (TN) and multiple sclerosis (MS) is well established. Many MS patients with TN have magnetic resonance imaging (MRI) evidence of a symptomatic demyelinating lesion.
What is a clinically isolated syndrome in the 21st century?
Georgina Arrambide
