Behavioural Brain Research




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سفارش

A comprehensive review and meta-analysis of neurological side effects related to second-generation antidepressants in individuals with major depressive disorder

Qi Zhou a,*, Xinming Li b, Dejiang Yang b, Chongyu Xiong c, Zhenrong Xiong

doi : 10.1016/j.bbr.2023.114431

Volume 447, 5 June 2023, 114431

Second-generation antidepressants (SGADs) often cause neurological side effects (SEs). This meta-analysis seeks to quantify the short-term rates of neurological SEs related to routinely used second-generation antidepressants used to treat major depressive disorder (MDD).

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Prelimbic neuron assemblies with delayed activation encode the economic decision-making process in a bandit game

Xiao Ma , Zhenni Wang , Shihao Lou , Hui Guo , Yupeng Yang

doi : 10.1016/j.bbr.2023.114419

Volume 447, 5 June 2023, 114419

The medial prefrontal cortex (mPFC) is critical to an animal’s value-based decision-making process. However, due to heterogeneity of local mPFC neurons, which neuron group and how it contributes to the alteration of the animal’s decision is yet to be explored. And the effect of empty reward in this process is often neglected.

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Association between cognitive impairment promoted by high-fat diet and increase in PTEN phosphorylation

Xiaoyi Chen a,b, Liang Ma c, Jingyu Zhao c,d, Xiaoyu Pan b, Shuchun Chen

doi : 10.1016/j.bbr.2023.114421

Volume 447, 5 June 2023, 114421

The purpose of this study was to observe the changes in memory impairment and hippocampal phosphorylated protein levels in mice caused by obesity, and to explore the key phosphorylation modification proteins and pathways of memory impairment induced by high-fat diet.

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Histone deacetylase 1 regulates haloperidol-induced motor side effects in aged mice

Bryan M. McClarty , Saikat Chakraborty , Guadalupe Rodriguez , Hongxin Dong

doi : 10.1016/j.bbr.2023.114420

Volume 447, 5 June 2023, 114420

Antipsychotic drugs prescribed to elderly patients with neuropsychiatric disorders often experience severe extrapyramidal side effects.

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Persicaria minor ameliorates the cognitive function of chronic cerebral hypoperfusion rats: Metabolomic analysis and potential mechanisms

Lim Wei Chun a,1, Ramesh Kumar Ramachandran a,1, Siti Fatin Farhanah Othman b,c,1, Ahmad Tarmizi Che Has d, Annie George e, Noorul Hamizah Mat a, Farah Wahida Suhaimi a, Nurul Aqmar Mohamad Nor Hazalin b,c,*, Zurina Hassan

doi : 10.1016/j.bbr.2023.114423

Volume 447, 5 June 2023, 114423

Persicaria minor (P. minor) is a herbal plant with many uses in food, perfume, and the medical industry. P. minor extract contains flavonoids with antioxidant and anticholinesterase capacity, which could enhance cognitive functions. P. minor extract has been proven to enhance memory.

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Disrupted functional networks within white-matter served as neural features in adolescent patients with conduct disorder

Fengmei Lu a,1, Yuanhong Guo a,1, Wei Luo a,1, Yue Yu a,1, Yi Zhao a, Shuai Ni a, Jiajia Chen a, Xiao Cai a, Chuntao Shen a, Xiaoping Wang b,c, Jiangjun He a,*, Guocheng Yang d,*, Qing Gao e,*, Zongling He a,*, Jiansong Zhou

doi : 10.1016/j.bbr.2023.114422

Volume 447, 5 June 2023, 114422

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On the effect of social cue valence in contextual memory persistence

Matheus Barbosa dos Santos a,1, Leonardo de Oliveira Guarnieri a,b,1, Paula Lunardi a,c,1, Grace Schenatto Pereira

doi : 10.1016/j.bbr.2023.114398

Volume 447, 5 June 2023, 114398

Social cues are valuable sensorial stimuli to the acquisition and retrieval of contextual memories. Here, we asked whether the valence of social cues would impact the formation of contextual memories. Adult male C57/BL6 mice were exposed to either conditioned place preference (CPP) or avoidance (CPA).

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Cortical and subcortical morphological alterations in postpartum depression

Wenqin Yang a, Yihan Jiang b, Lin Ma a, Mengjia Xiao a, Mingke Liu a, Zhanbing Ren c, Yuanchao Zhang b,*, Liangbo Hu

doi : 10.1016/j.bbr.2023.114414

Volume 447, 5 June 2023, 114414

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Interaction of nicotine and social reward in group-reared male adolescent rats

Diana M. Cort �es-Pati ̃no, Valentyna Martin Neira, Hans Ballesteros-Acosta, Angie Bustos-Rangel, Marisol R. Lamprea

doi : 10.1016/j.bbr.2023.114432

Volume 447, 5 June 2023, 114432

Adolescents exhibit great sensitivity to nicotine and social interaction; accordingly, when both stimuli are presented together, they interact to enhance the incentive value of the context in which they occur.

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Sexual experience induces a preponderance of mushroom spines in the medial prefrontal cortex and nucleus accumbens of male rats

Marisela Hern �andez-Gonz �alez a, Francisco Javier Barrera-Cobos a, Enrique Hern �andez-Arteaga b, Ignacio Gonz �alez-Burgos c, Mario Flores-Soto d, Miguel Angel Guevara a, Pedro Manuel Cortes

doi : 10.1016/j.bbr.2023.114437

Volume 447, 5 June 2023, 114437

Sexual experience improves copulatory performance in male rats. Copulatory performance has been associated with dendritic spines density in the medial prefrontal cortex (mPFC) and nucleus accumbens (NAcc), structures involved in the processing of sexual stimuli and the manifestation of sexual behavior.

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Chronic early-life social isolation enhances spatial memory in male and female rats

Saeideh Davari a, Nicole D’Costa a, Reza Ramezan b, John G. Mielke

doi : 10.1016/j.bbr.2023.114433

Volume 447, 5 June 2023, 114433

Social adversity during childhood and adolescence can alter brain development in ways that may increase the likelihood of many prominent mental illnesses. To determine the underlying mechanisms, several animal models have been developed, such as Chronic Early-Life Social Isolation (CELSI), which sees rats isolated for several weeks after weaning.

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Effects of 5-HT2C receptor stimulation in male mice on behaviour and Fos expression: Feeding, reward and impulsivity

Paul J. Fletcher a,b,c,*, Arya Rahbarnia a,c, Zhaoxia Li a, Xiaodong Ji a, Guy A. Higgins d,e, Douglas Funk a, A.D. Lˆe

doi : 10.1016/j.bbr.2023.114438

Volume 447, 5 June 2023, 114438

Serotonin modulates many motivated behaviours via multiple receptor subtypes. Agonists at 5-HT2C receptors have potential for treating behavioural problems associated with obesity and drug use.

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miR-181c-5p suppresses neuronal pyroptosis via NLRP1 in Alzheimer’s disease

Tingting Wang a, Qionghua Long a, Yang Hu a, Yongli Yang a, Xingguo Li b,*, Huan Wei

doi : 10.1016/j.bbr.2023.114387

Volume 447, 5 June 2023, 114387

Alzheimer's disease (AD) is neurodegenerative disease common in the elderly, whose pathological mechanism is the deposition of amyloid-β (Aβ) plaques and neurofibrillary tangles in the brain.

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The 2210408F21Rik/miR-1968–5p/Hras axis regulates synapse-related proteins in a mouse model of depressive-like behaviors through a ceRNA mechanism

Jiang Zhu a,*, Sen Guo b,c, Shaofu Hu a, Qihang Chen

doi : 10.1016/j.bbr.2023.114440

Volume 447, 5 June 2023, 114440

Abnormal expression of long non-coding RNAs (lncRNAs) has been correlated with depressive disorders, but limited data are available on the lncRNA-microRNA (miRNA/miR)-messenger RNA (mRNA) competitive endogenous RNA (ceRNA) mechanism in depression.

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Corrigendum to: “Neuroprotective effect of Anethole against rotenone induced non-motor deficits and oxidative stress in rat model of Parkinson’s disease� Behav. Brain Res. 437 (2023) 114100

Sadegh Moradi Vastegani a, Seyed Esmaeil Khoshnam a, Esrafil Mansouri b, Somayeh Hajipour a, Samireh Ghafouri a,c, Nima Bakhtiari d, Alireza Sarkaki a,c,*, Yaghoob Farbood

doi : 10.1016/j.bbr.2023.114412

Volume 447, 5 June 2023, 114412

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