Behavioural Brain Research




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سفارش

Intestinal permeability and its significance in psychiatric disorders – A narrative review and future perspectives

Jakub Wasiak a, Oliwia Gawlik-Kotelnicka

doi : 10.1016/j.bbr.2023.114459

Volume 448, 25 June 2023, 114459

The topic of increased intestinal permeability and its impact on the human body is increasingly being addressed by researchers. It is associated with disruption of the intestinal barrier, leading to the “leaky gut� syndrome.

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Probing different paradigms of morphine withdrawal on sleep behavior in male and female C57BL/6J mice

Madigan L. Bedard a,b, Julia Sparks Lord c,d, Patric J. Perez a, Isabel M. Bravo a, Adonay T. Teklezghi a, Lisa M. Tarantino e,f, Graham H. Diering c,d, Zoe A. McElligott

doi : 10.1016/j.bbr.2023.114441

Volume 448, 25 June 2023, 114441

Opioid misuse has dramatically increased over the last few decades resulting in many people suffering from opioid use disorder (OUD). The prevalence of opioid overdose has been driven by the development of new synthetic opioids, increased availability of prescription opioids, and more recently, the COVID-19 pandemic.

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Involvement of cortical projections to basolateral amygdala in context-induced reinstatement of ethanol-seeking in rats

Gabrielle Emily Boaventura Tavares , Paula Cristina Bianchi , Thais Suemi Yokoyama , Paola Palombo , F �abio Cardoso Cruz

doi : 10.1016/j.bbr.2023.114435

Volume 448, 25 June 2023, 114435

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Prepulse inhibition of the acoustic startle reflex impairment by 5-HT2A receptor activation in the inferior colliculus is prevented by GABAA receptor blockade in the pedunculopontine tegmental nucleus

Rodolpho Pereira de Oliveira a, Thais Yokoyama b, Lucas de Santana Cardoso Thomaz a, Jos �e Sim ̃oes de Andrade a, Alexia dos Anjos Santos b, Vinícius de Carvalho Mendonça a, Tatiana Rosenstock c, Marinete Pinheiro Carrera d, Priscila Medeiros e,f,g,h,i, F �abio Cardoso Cruz b, Norberto Cysne Coimbra e,f,g, Regina Cl �audia Barbosa Silva

doi : 10.1016/j.bbr.2023.114436

Volume 448, 25 June 2023, 114436

The relationship between serotonin dysfunction and schizophrenia commenced with the discovery of the effects of lysergic acid diethylamide (LSD) that has high affinity for 5-HT2A receptors. Activation of these receptors produces perceptual and behavioural changes such as illusions, visual hallucinations and locomotor hyperactivity.

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Cannabinoid CB2 receptors modulate alcohol induced behavior, and neuro-immune dysregulation in mice

Berhanu Geresu Kibret a,1,*, Aaliyah Roberts a, Adam Kneebone a, Shymaa Embaby a, Justin Fernandez a, Qing-Rong Liu b, Emmanuel S. Onaivi

doi : 10.1016/j.bbr.2023.114439

Volume 448, 25 June 2023, 114439

The identification of additional lipid mediators, enzymes, and receptors revealed an expanded endocannabinoid system (ECS) called the endocannabinoidome (eCBome).

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Ebselen alleviates white matter lesions and improves cognitive deficits by attenuating oxidative stress via Keap1/Nrf2 pathway in chronic cerebral hypoperfusion mice

Fuxing Dong a,b,1, Weixing Yan a,1, Qiqi Meng a, Xueli Song a, Bing Cheng a, Yaping Liu c, Ruiqin Yao a,

doi : 10.1016/j.bbr.2023.114444

Volume 448, 25 June 2023, 114444

Oxidative stress is crucial in cerebral white matter lesions (WMLs) induced by chronic cerebral hypoperfusion. Therefore, ameliorating oxidative damage is considered to be a beneficial strategy for the treatment of WMLs.

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Environmental conditions of recognition memory testing induce neurovascular changes in the hippocampus in a sex-specific manner in mice

Alice Cadoret, Laurence Dion-Albert, Sara Amrani, Laurianne Caron, Mathilde Th �eberge, Audrey Turmel, Manon Lebel, Caroline Menard

doi : 10.1016/j.bbr.2023.114443

Volume 448, 25 June 2023, 114443

Experiences are linked to emotions impacting memory consolidation and associated brain neuronal circuits. Posttraumatic stress disorder is an example of strong negative emotions affecting memory processes by flashbacks of past traumas.

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Chronic social defeat alters behaviors and neuronal activation in the brain of female Mongolian gerbils

Yongliang Pan a,*, Qiuyue Mou a, Zhexue Huang a, Senyao Chen a, Yilei Shi a, Mengfan Ye a, Mingqin Shao c, Zuoxin Wang

doi : 10.1016/j.bbr.2023.114456

Volume 448, 25 June 2023, 114456

Chronic social defeat has been found to be stressful and to affect many aspects of the brain and behaviors in males. However, relatively little is known about its effects on females.

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Morphine and dopamine: Low dose apomorphine can prevent both the induction and expression of morphine locomotor sensitization and conditioning

Joaquim Barbosa Leite Júnior a, Luiz Gustavo Soares Carvalho Crespo a, Richard Ian Samuels b, Norberto Cysne Coimbra c, Robert J. Carey d, Marinete Pinheiro Carrera

doi : 10.1016/j.bbr.2023.114434

Volume 448, 25 June 2023, 114434

The disinhibition of dopamine neurons in the VTA by morphine is considered an important contributor to the reward potency of morphine. In this report, three experiments were conducted in which a low dose of apomorphine (0.05 mg/kg) was used as a pretreatment to reduce dopamine activity.

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Integration of simultaneous fMRI and EEG source localization in emotional decision problems

Zhongyi Jiang a, Yin Liu a, Wenjie Li b, Yakang Dai d, Ling Zou

doi : 10.1016/j.bbr.2023.114445

Volume 448, 25 June 2023, 114445

Simultaneous EEG-fMRI has been a powerful technique to understand the mechanism of the brain in recent years. In this paper, we develop an integrating method by integrating the EEG data into the fMRI data based on the parametric empirical Bayesian (PEB) model to improve the accuracy of the brain source location.

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Evaluations of memory, anxiety, and the growth factor IGF-1R after post-surgical menopause treatment with a highly selective progestin

Victoria E. Bernaud a,b, Stephanie V. Koebele a,b, Steven N. Northup-Smith a,b, Mari N. Willeman a,b,c, Charlotte Barker a,b, Alex Schatzki-Lumpkin a,b, Maria Valenzuela Sanchez a,b, Heather A. Bimonte-Nelson

doi : 10.1016/j.bbr.2023.114442

Volume 448, 25 June 2023, 114442

Progestogens are a key component of menopausal hormone therapies. While some progestogens can be detrimental to cognition, there is preclinical evidence that progestogens with a strong progesterone-receptor affinity benefit some molecular mechanisms believed to underlie cognitive function.

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The para-hippocampal–medial frontal gyrus functional connectivity mediates the relationship between dispositional optimism and procrastination

Ye Liu a, Feng Zhou a,b, Rong Zhang a, Tingyong Feng

doi : 10.1016/j.bbr.2023.114463

Volume 448, 25 June 2023, 114463

Procrastination is a prevalent phenomenon throughout the world, which can lead to worse consequences across life domains, such as academic performance, mental health, and even public policy.

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Muscarinic cholinergic receptor antagonism impairs spatial memory retrieval and minimizes retrieval-induced alterations in matrix metalloproteinase-9

Mikel L. Olson *, Bretton Badenoch , Megan Blatti , Christine Buching , Nic Glewwe

doi : 10.1016/j.bbr.2023.114460

Volume 448, 25 June 2023, 114460

Cholinergic dysfunction in the hippocampus causes memory impairment, and degradation of the forebrain cholinergic system has been implicated in several neurological disorders.

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