Meiyu Song, Peng Xu, Li Wang, Jie Liu, Xiaofei Hou
doi : 10.1111/aji.13682
Preeclampsia (PE) is an obstetric disease involving multiple systems, which account for maternal and fetal complications and increased mortality. Circular RNAs (circRNAs) were recently deemed to associate with the pathogenesis of PE. This study aims to clarify the correlation between circRNA hsa_circ_0001326 and PE and explore its biological function in PE.
Toshiyuki Minami, Yota Tsuzuki, Yukiko Tanaka, Jo Kitawaki, Taisuke Mori
doi : 10.1111/aji.13689
Endometriosis is a proliferative disease characterized by cytokine-induced inflammation. The objective of this study was to assess cell growth and PGE2 production induced by TNF-α in endometriotic stromal cells (ESCs) in spheroid cell culture and to identify the signaling pathway involved with a view to finding new therapeutic targets for endometriosis.
Hyeon Ji Kim, Kyo Hoon Park, Eunwook Joo, Jung Yun Lee, Eun Mi Im, Kyong-No Lee, Sue Shin
doi : 10.1111/aji.13697
To investigate whether altered expression of various inflammation-, angiogenesis-, and extracellular matrix-related mediators in cervicovaginal fluid (CVF) could be independently associated with acute histological chorioamnionitis (HCA), microbial-associated HCA, and funisitis in women with preterm premature rupture of membranes (PPROM).
Dave M. Mathew, Nicole A. Ampatey, Jaime A. Aaronson, Jon D. Samuels, Danielle McCullough, Robert S. White
doi : 10.1111/aji.13698
Amidst the ongoing coronavirus disease 2019 (COVID-19) pandemic, evidence suggests racial and ethnic disparities in COVID-19-related outcomes. Given these disparities, it is important to understand how such patterns may translate to high-risk cohorts, including obstetric patients.
Shrimati Shetty, Shrinath Kshirsagar, Shweta Bansal, Savita Rangarajan, Varsha Phadke
doi : 10.1111/aji.13700
Preeclampsia (PE) is a serious, unpredictable hypertensive disorder of pregnancy present in around 8–10% of all pregnancies resulting in high rate of maternal and fetal morbidity and mortality.
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