American Journal of Reproductive Immunology




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سفارش






Hsa_circ_0001326 inhibited the proliferation, migration, and invasion of trophoblast cells via miR-145-5p/TGFB2 axis

Meiyu Song, Peng Xu, Li Wang, Jie Liu, Xiaofei Hou

doi : 10.1111/aji.13682

Preeclampsia (PE) is an obstetric disease involving multiple systems, which account for maternal and fetal complications and increased mortality. Circular RNAs (circRNAs) were recently deemed to associate with the pathogenesis of PE. This study aims to clarify the correlation between circRNA hsa_circ_0001326 and PE and explore its biological function in PE.

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The Tpl2-MEK pathway plays a critical role in spheroid-cultured endometriotic stromal cells

Toshiyuki Minami, Yota Tsuzuki, Yukiko Tanaka, Jo Kitawaki, Taisuke Mori

doi : 10.1111/aji.13689

Endometriosis is a proliferative disease characterized by cytokine-induced inflammation. The objective of this study was to assess cell growth and PGE2 production induced by TNF-α in endometriotic stromal cells (ESCs) in spheroid cell culture and to identify the signaling pathway involved with a view to finding new therapeutic targets for endometriosis.

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Expression of inflammatory, angiogenic, and extracellular matrix-related mediators in the cervicovaginal fluid of women with preterm premature rupture of membranes: Relationship with acute histological chorioamnionitis

Hyeon Ji Kim, Kyo Hoon Park, Eunwook Joo, Jung Yun Lee, Eun Mi Im, Kyong-No Lee, Sue Shin

doi : 10.1111/aji.13697

To investigate whether altered expression of various inflammation-, angiogenesis-, and extracellular matrix-related mediators in cervicovaginal fluid (CVF) could be independently associated with acute histological chorioamnionitis (HCA), microbial-associated HCA, and funisitis in women with preterm premature rupture of membranes (PPROM).

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The association of race and ethnicity on obstetric patients’ COVID-19 outcomes: A summary of current literature

Dave M. Mathew, Nicole A. Ampatey, Jaime A. Aaronson, Jon D. Samuels, Danielle McCullough, Robert S. White

doi : 10.1111/aji.13698

Amidst the ongoing coronavirus disease 2019 (COVID-19) pandemic, evidence suggests racial and ethnic disparities in COVID-19-related outcomes. Given these disparities, it is important to understand how such patterns may translate to high-risk cohorts, including obstetric patients.

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COVID-19 and preeclampsia: The unique and the mutually nonexclusive clinical manifestations

Shrimati Shetty, Shrinath Kshirsagar, Shweta Bansal, Savita Rangarajan, Varsha Phadke

doi : 10.1111/aji.13700

Preeclampsia (PE) is a serious, unpredictable hypertensive disorder of pregnancy present in around 8–10% of all pregnancies resulting in high rate of maternal and fetal morbidity and mortality.

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