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New Paradigms to Address Long-Term Exercise Adherence, An Achilles Heel of Lifestyle Interventions.
Peters, Anthony E. MD, MS; Kraus, William E. MD; Mentz, Robert J. MD
doi : 10.1161/CIRCULATIONAHA.123.064161
Volume 147(21) pgs. 1565-1636 May 23, 2023
Long-Term Outcomes of Brugada Substrate Ablation: A Report from BRAVO (Brugada Ablation of VF Substrate Ongoing Multicenter Registry).
Nademanee, Koonlawee MD; Chung, Fa-Po MD; Sacher, Frederic MD, PhD; Nogami, Akihiko MD, PhD; Nakagawa, Hiroshi MD, PhD; Jiang, Chenyang MD; Hocini, Meleze MD; Behr, Elijah MA, MBBS; Veerakul, Gumpanart MD; Jan Smit, Jaap MD, PhD; Wilde, Arthur A.M. MD, PhD; Chen, Shih-Ann MD; Yamashiro, Kohei MD; Sakamoto, Yuichiro MD; Morishima, Itsuro MD, PhD; Das, Mithilesh K. MD; Khongphatthanayothin, Apichai MD; Vardhanabhuti, Saran PhD; Haissaguerre, Michel MD
doi : 10.1161/CIRCULATIONAHA.122.063367
Treatment options for high-risk Brugada syndrome (BrS) with recurrent ventricular fibrillation (VF) are limited. Catheter ablation is increasingly performed but a large study with long-term outcome data is lacking.
Treatment of Brugada Syndrome in 2023: Know Where You Come From to Know Where You Are Going.
Viskin, Sami; Rosso, Raphael MD
Severe Infection and Risk of Cardiovascular Disease: A Multicohort Study.
Sipila, Pyry N. MD, PhD; Lindbohm, Joni V. MD, PhD; Batty, G. David DSc; Heikkila, Nelli MD, PhD; Vahtera, Jussi MD, PhD; Suominen, Sakari DMedSci; Vaananen, Ari PhD; Koskinen, Aki MSc; Nyberg, Solja T. PhD; Meri, Seppo MD, PhD; Pentti, Jaana MSc; Warren-Gash, Charlotte PhD; Hayward, Andrew C. MD; Kivimaki, Mika PhD
doi : 10.1161/CIRCULATIONAHA.122.061183
The excess risk of cardiovascular disease associated with a wide array of infectious diseases is unknown. We quantified the short- and long-term risk of major cardiovascular events in people with severe infection and estimated the population-attributable fraction.
Economic Outcomes of Transcatheter Versus Surgical Aortic Valve Replacement in Patients with Severe Aortic Stenosis and Low Surgical Risk: Results from the PARTNER 3 Trial.
Galper, Benjamin Z. MD, MPH; Chinnakondepalli, Khaja M. MS; Wang, Kaijun PhD; Magnuson, Elizabeth A. ScD; Lu, Michael PhD; Thourani, Vinod H. MD; Kodali, Susheel MD; Makkar, Raj MD; Herrmann, Howard C. MD; Kapadia, Samir MD; Williams, Mathew MD; Webb, John MD; Smith, Craig R. MD; Mack, Michael J. MD; Leon, Martin B. MD; Cohen, David J. MD, MSc; on behalf of the PARTNER Investigators
doi : 10.1161/CIRCULATIONAHA.122.062481
In patients with severe symptomatic aortic stenosis at low surgical risk, transfemoral transcatheter aortic valve replacement (TAVR) with the SAPIEN 3 valve has been shown to reduce the composite of death, stroke, or rehospitalization at 2-year follow-up compared with surgical aortic valve replacement (SAVR).
SOX17 Enhancer Variants Disrupt Transcription Factor Binding And Enhancer Inactivity Drives Pulmonary Hypertension.
Walters, Rachel PhD; Vasilaki, Eleni MSc; Aman, Jurjan PhD; Chen, Chien-Nien PhD; Wu, Yukyee PhD; Liang, Olin D. PhD; Ashek, Ali PhD; Dubois, Olivier PhD; Zhao, Lin PhD; Sabrin, Farah PhD; Cebola, Ines PhD; Ferrer, Jorge PhD; Morrell, Nicholas W. MD; Klinger, James R. MD; Wilkins, Martin R. MD; Zhao, Lan PhD ,*; Rhodes, Christopher J. PhD ,,*
doi : 10.1161/CIRCULATIONAHA.122.061940
Pulmonary arterial hypertension (PAH) is a rare disease characterized by remodeling of the pulmonary arteries, increased vascular resistance, and right-sided heart failure.
Subepicardial Cardiomyopathy: A Disease Underlying J-Wave Syndromes and Idiopathic Ventricular Fibrillation.
Miles, Chris BSc, MBChB, PhD; Boukens, Bastiaan J. PhD; Scrocco, Chiara MD; Wilde, Arthur A.M. MD, PhD; Nademanee, Koonlawee MD, CCDS; Haissaguerre, Michel MD; Coronel, Ruben MD, PhD ,*; Behr, Elijah R. MA, MD ,,*
doi : 10.1161/CIRCULATIONAHA.122.061924
AB Brugada syndrome (BrS), early repolarization syndrome (ERS), and idiopathic ventricular fibrillation (iVF) have long been considered primary electrical disorders associated with malignant ventricular arrhythmia and sudden cardiac death.
Telomeres Fuse During Cardiomyocyte Maturation.
Aix, Esther PhD ,*; Gallinat, Alex PhD ,*; Yago-Diez, Carla PhD; Lucas, Javier MS; Gomez, Manuel Jose PhD; Benguria, Alberto PhD; Freitag, Patricia; Cortez-Toledo, Elizabeth; Fernandez de Manuel, Laura PhD; Garcia-Cuasimodo, Lucia BS; Sanchez-Iranzo, Hector PhD; Montoya, Maria C. PhD; Dopazo, Ana PhD; Sanchez-Cabo, Fatima PhD; Mercader, Nadia PhD; Lopez, Javier E. MD; Fleischmann, Bernd K. MD; Hesse, Michael PhD; Flores, Ignacio PhD
