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Computerized cardiotocography and Dawes–Redman criteria: how should we interpret criteria not met?
T. Stampalija, A. Bhide, A. E. P. Heazell, A. Sharp, C. Lees
doi : 10.1002/uog.26198
Fetal endoscopic tracheal occlusion for congenital diaphragmatic hernia: systematic review and meta-analysis
Y. Chen, R. Xu, X. Xie, T. Wang, Z. Yang, J. Chen
doi : 10.1002/uog.26164
It is debated whether fetal endoscopic tracheal occlusion (FETO) is beneficial to fetuses with congenital diaphragmatic hernia (CDH) and whether FETO has different effects in moderate and severe CDH. We conducted a systematic review and meta-analysis including the latest evidence to assess the overall effects of FETO on clinical outcomes of CDH.
Pre-eclampsia screening in Denmark (PRESIDE): national validation study
I. Riishede, L. Rode, L. Sperling, M. Overgaard, J. D. Ravn, P. Sandager, H. Skov, S. R. Wagner, P. Nørgaard, T. D. Clausen, C. A. Juel Jensen, K. Pihl, F. S. Jørgensen, J. K. Munk, H. J. Zingenberg, N. G. Pedersen, M. R. Andersen, A. Wright, D. Wright, A. Tabor, C. K. Ekelund
doi : 10.1002/uog.26183
To investigate the predictive performance of the Fetal Medicine Foundation (FMF) first-trimester screening algorithm for pre-eclampsia in a Danish population and compare screening performance with that of the current Danish strategy, which is based on maternal risk factors.
ASPRE trial: effects of aspirin on mean arterial blood pressure and uterine artery pulsatility index trajectories in pregnancy
D. L. Rolnik, A. Syngelaki, N. O'Gorman, D. Wright, L. C. Poon, K. H. Nicolaides
doi : 10.1002/uog.26222
The mechanism by which aspirin prevents pre-eclampsia is poorly understood, and its effects on biomarkers throughout pregnancy are unknown. We aimed to investigate the effects of aspirin on mean arterial pressure (MAP) and mean uterine artery pulsatility index (UtA-PI) using repeated measures from women at increased risk of preterm pre-eclampsia.
Clinical utility of expanded non-invasive prenatal screening compared with chromosomal microarray analysis in over 8000 pregnancies without major structural anomaly
I. Maya, L. Salzer Sheelo, D. Brabbing-Goldstein, R. Matar, S. Kahana, I. Agmon-Fishman, C. Klein, M. Gurevitch, L. Basel-Salmon, L. Sagi-Dain
doi : 10.1002/uog.26177
To evaluate the theoretical added value of two types of non-invasive prenatal screening (NIPS) expansions in pregnancies without major structural anomalies over the commonly used NIPS for chromosomes 13, 18, 21, X and Y (5-NIPS) and to compare them with the added value of chromosomal microarray analysis (CMA).
Adverse outcome following selective termination of presenting twin vs non-presenting twin
H. Miremberg, H. Rosen, B. Weisz, D. Tirosh, R. Hershkovitz, S. Stern, S. Porat, B. Beloshevski, Y. Melcer, Y. Goldberg, N. Boms Yonai, M. Awawdeh, Z. Leibovitz, J. Shalev, L. Gindes
doi : 10.1002/uog.26170
Data are lacking on the impact on pregnancy outcome of the position of the abnormal fetus in a discordant twin pregnancy undergoing selective termination (ST). Tissue maceration post ST of the presenting twin may lead to early rupture of membranes, amnionitis and preterm labor. The aim of this study was to evaluate pregnancy complications and outcome following ST of the presenting vs non-presenting twin.
Plugging membranes after fetoscopy in congenital diaphragmatic hernia: early cost-effectiveness analysis
J. Janssen, J. van Drongelen, W. F. Daamen, J. P. C. Grutters
doi : 10.1002/uog.26163
Fetal endoscopic tracheal occlusion (FETO) improves neonatal survival of fetuses with congenital diaphragmatic hernia (CDH). However, FETO also increases the risk of preterm prelabor rupture of membranes (PPROM) and preterm delivery (PTD), as fetal membrane defects after fetoscopy do not heal.
Implication of chromosomal microarray analysis prior to in-utero repair of fetal open neural tube defect
R. Zemet, E. Krispin, R. M. Johnson, N. R. Kumar, L. E. Westerfield, S. Stover, D. G. Mann, J. Castillo, H. A. Castillo, A. A. Nassr, M. Sanz Cortes, R. Donepudi, J. Espinoza, W. E. Whitehead, M. A. Belfort, A. A. Shamshirsaz, I. B. Van den Veyver
doi : 10.1002/uog.26152
In-utero repair of open neural tube defects (ONTD) is an accepted treatment option with demonstrated superior outcome for eligible patients. While current guidelines recommend genetic testing by chromosomal microarray analysis (CMA) when a major congenital anomaly is detected prenatally, the requirement for an in-utero repair, based on the Management of Myelomeningocele Study (MOMS) criteria, is a normal karyotype. In this study, we aimed to evaluate if CMA should be recommended as a prerequisite for in-utero ONTD repair.
Presurgery motor level assessment for prediction of motor level at birth in fetuses undergoing prenatal repair of open spina bifida: time to abandon anatomical level in counseling
N. Maiz, S. Arévalo, P. GarcÃa-Manau, M. Meléndez, C. Giné, C. Rodó, M. López, E. Carreras
doi : 10.1002/uog.26180
First, to investigate the correlation between prenatal presurgery anatomical and motor levels of the lesion with motor level at birth in cases undergoing prenatal repair of open spina bifida and, second, to identify factors leading to a loss of two or more motor levels between the presurgery and postnatal assessments.
Impact on postoperative, neonatal and 2-year neurodevelopmental outcomes of UA-AREDF during and after fetal spina bifida repair
L. Ruegg, L. Vonzun, B. Latal, U. Moehrlen, L. Mazzone, M. Meuli, F. Krähenmann, N. Ochsenbein-Kölble
doi : 10.1002/uog.26118
Absent or reversed end-diastolic flow (AREDF) in the umbilical artery (UA) on Doppler is a known phenomenon during fetal interventions, such as fetal open spina bifida (OSB) repair. We aimed to evaluate the clinical importance of these Doppler findings by investigating the impact of UA-AREDF on postoperative, neonatal and 2-year neurodevelopmental outcomes.
Spectrum of brain malformations in fetuses with mild tubulinopathy
R. Hagege, K. Krajden Haratz, G. Malinger, L. Ben-Sira, Z. Leibovitz, D. Heron, L. Burglen, R. Birnbaum, S. Valence, B. Keren, L. Blumkin, J.-M. Jouannic, T. Lerman-Sagie, C. Garel
doi : 10.1002/uog.26140
To report on a large cohort of fetuses with mild forms of tubulinopathy and to define prenatal ultrasound and magnetic resonance imaging (MRI) features that can facilitate prenatal diagnosis.
Halo sign in fetal cytomegalovirus infection: cerebral imaging abnormalities and postmortem histopathology in 35 infected fetuses
A. Hawkins-Villarreal, K. Castillo, A. Nadal, S. Planas, A. L. Moreno-Espinosa, A. Alarcón, M. Rebollo-Polo, F. Figueras, E. Gratacós, E. Eixarch, A. Goncé
doi : 10.1002/uog.26173
To evaluate the correlation of periventricular echogenic halo (halo sign) with histopathological findings and its association with other brain imaging abnormalities in fetuses with cytomegalovirus (CMV) infection.
Correlation of short-term variation derived from novel ambulatory fetal electrocardiography monitor with computerized cardiotocography
B. Liu, B. Thilaganathan, A. Bhide
doi : 10.1002/uog.26191
To compare short-term variation (STV) outputs from a novel self-applied non-invasive fetal electrocardiography (NIFECG) device with those obtained on computerized cardiotocography (cCTG). Technological and algorithmic limitations and mitigation strategies were also evaluated.
Phase-rectified signal averaging: correlation between two monitors and relationship with short-term variation of fetal heart rate
B. Liu, B. Thilaganathan, A. Bhide
doi : 10.1002/uog.26192
To establish the correlation between phase-rectified signal averaging (PRSA) outputs obtained from a novel self-applicable non-invasive fetal electrocardiography (NIFECG) monitor with those from computerized cardiotocography (cCTG). A secondary objective was to evaluate the potential for remote assessment of fetal wellbeing by determining the relationship between PRSA and short-term variation (STV).
Use of computerized cardiotocography and Dawes–Redman criteria: results from a binational survey
M. S. Scalia, C. Lees, G. Zamagni, T. Ghi, A. Bhide, L. Monasta, G. Ricci, G. Maso, H. Valensise, T. Stampalija
doi : 10.1002/uog.26225
Assay interference leading to erroneous pregnancy-associated plasma protein-A results
S. L. Jones, I. Mills, M. Petchey, C. Williams
doi : 10.1002/uog.26143
Prenatal diagnosis of congenital left ventricular diverticulum
B. Ma, Z.-H. Yan, T.-G. Li, F. Nie
doi : 10.1002/uog.26137
Fetoscopic laser ablation in pregnancies with Type-II vasa previa
R. Papanna, N. Agarwal, E. P. Bergh, C. Brock, J. Espinoza, A. Johnson
doi : 10.1002/uog.26153
A good screening test: not just high sensitivity
T.-Y. Lei, Y.-Y. Li, D.-Z. Li
doi : 10.1002/uog.26227
A good screening test: benefits and limitations
I. Maya, L. Salzer Sheelo, L. Basel-Salmon, L. Sagi-Dain
doi : 10.1002/uog.26228
We thank Lei et al. for their commentary on our manuscript1 and for raising interesting and important points regarding the utility of non-invasive prenatal screening (NIPS) vs invasive testing.
Four-dimensional imaging of umbilical-vein-to-right-atrium shunt in fetus with Type-I Abernethy malformation
B. Karmegaraj
doi : 10.1002/uog.26214
ISUOG Practice Guidelines (updated): fetal cardiac screening
J. S. Carvalho, R. Axt-Fliedner, R. Chaoui, J. A. Copel, B. F. Cuneo, D. Goff, L. Gordin Kopylov, K. Hecher, W. Lee, A. J. Moon-Grady, H. A. Mousa, H. Munoz, D. Paladini, F. Prefumo, E. Quarello, J. Rychik, B. Tutschek, M. Wiechec, S. Yagel
doi : 10.1002/uog.26224
