Yongyi Jiao, Li Sun, Xiaotong Xie, Hong Liu, Yu Zhao, Haifeng Ni, Xiaoliang Zhang
doi : 10.1111/nep.14156
Calciphylaxis is a rare disease, predominantly in chronic kidney disease (CKD), characterized by high morbidity and mortality. Data from the Chinese population have been an invaluable resource for a better understanding of natural history, optimal treatments and outcomes of calciphylaxis.
Ziyuan Liu, Huilong Xiang, Qin Deng, Wanting Fu, Yang Li, Zejun Yu, Yinsheng Qiu, Zhinan Mei, Lingyun Xu
doi : 10.1111/nep.14159
Inflammation and apoptosis are main pathological processes that lead to the development of hyperuricemic nephropathy (HN). This study aims to explore whether baicalin (BA) and baicalein (BAI) can relieve the damage through PI3K/AKT/NF-κB signal pathway and provide more reliable and precise evidence for the treatment of HN.
Georgina L. Irish, Laura Cuthbertson, Alex Kitsos, Tim Saunder, Philip A. Clayton, Matthew D. Jose
doi : 10.1111/nep.14160
Predicting progression to kidney failure for patients with chronic kidney disease is essential for patient and clinicians' management decisions, patient prognosis, and service planning. The Tangri et al Kidney Failure Risk Equation (KFRE) was developed to predict the outcome of kidney failure. The KFRE has not been independently validated in an Australian Cohort.
Hiroshi Nagae, Yuki Ueno, Masumi Shojima, Keita Takae, Yusuke Kuroki, Ritsuko Katafuchi
doi : 10.1111/nep.14163
Although the number of elderly patients with chronic kidney disease (CKD) has increased, few studies have examined their prognosis.
Keiichi Ohata, Takeshi Sugaya, Hanh Nhung Nguyen, Yuri Hatanaka, Kinuko Uno, Marika Tohma, Tsuyoshi Oikawa, Hiroshi Nagabukuro, Kanako Kuniyeda, Atsuko Kamijo-Ikemori, Noriko Suzuki-Kemuriyama, Dai Nakae, Eisei Noiri, Katsuhiro Miyajima
doi : 10.1111/nep.14162
Urinary liver-type fatty acid binding protein (L-FABP) has potential utility as an early prognostic biomarker ahead of traditional severity scores in coronavirus disease 2019 and sepsis, however, the mechanism of elevated urinary L-FABP in the disease has not been clearly elucidated. We investigated the background mechanisms of urinary L-FABP excretion through non-clinical animal model focusing on histone, which is one of the aggravating factors in these infectious diseases.
Baoqiao Wu, Ji He, Yueming Liu, Yan Ren, Qiang He
doi : 10.1111/nep.14157
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