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Practical Management of HRS-AKI in the Era of Terlipressin: What the Gastroenterologist Needs to Know.
Wong, Florence MD 1; Kwo, Paul MD 2
doi : 10.14309/ajg.0000000000002115
Volume 118(6) pgs. 915-1104 June 2023
A Practical Guide to Use of Risankizumab.
Horst, Sara MD, MPH, FACG 1
Esophageal Bulla in Epidermolysis Bullosa.
Chang, ZeNan Li MD, PhD 1; Bazarbashi, Ahmad Najdat MD 1
A Rare Cause of Colonic Obstruction in Inflammatory Bowel Disease.
Le Cosquer, Guillaume MD 1; Celerier, Bertrand MD 2; Laharie, David MD, PhD 1
Inverted Meckel Diverticulum Diagnosed, Treated, and Followed Up by Enteroscopy.
Jia, Xiaoqing MD 1,2,*; Ma, Tian MD 1,2,*; Liu, Guanqun MD 1,2; Zuo, Xiuli MD, PhD 1,2
Gastric Sarcoma: A Very Rare and Aggressive Gastric Cancer.
Tang, Si Ying MRCP (UK) 1; Wong, Neng Wei MRCS (Edinburgh) 2; Lee, Jaslyn Jie Lin MBBS 3
Persistent Gastrostomy Site Infection Because of Rib Fracture.
Masaki, Shigenori MD 1; Yamada, Chizuko RN 2
A Novel Endoscopic Technique for Positioning Salivary Bypass Tubes.
Fugazza, Alessandro MD 1; Massimi, Davide MD 1; Cugini, Giovanni MD 2; Colombo, Matteo MD 1; Koleth, Glenn MD 1; Andreozzi, Marta MD 1; De Virgilio, Armando MD 2,3; Spriano, Giuseppe MD 2,3; Repici, Alessandro MD 1,3
Isolated Small Bowel Varices Diagnosed by Contrast-Enhanced Ultrasound.
Hayashi, Manabu MD, PhD 1; Matsuda, Mitsuko 2; Yamadera, Yukio 2; Nakamura, Jun MD, PhD 1,3; Fujita, Masashi MD 1; Abe, Kazumichi MD, PhD 1; Takahashi, Atsushi MD, PhD 1; Takagi, Tadayuki MD, PhD 1; Hikichi, Takuto MD, PhD 3; Ohira, Hiromasa MD, PhD 1
Continuing Medical Education Questions: June 2023.
Lanspa, Stephen J. MD, FACG
doi : 10.14309/ajg.0000000000002308
AB Article Title: American Gastroenterological Association-American College of Gastroenterology Clinical Practice Guideline: Pharmacological Management of Chronic Idiopathic Constipation (C) The American College of Gastroenterology 2023. All Rights Reserved.
Continuing Medical Education Questions: June 2023.
Dulaney, David T. MD
doi : 10.14309/ajg.0000000000002309
AB Article Title: Long-term Outcomes of Biological Therapy in Crohn's Disease Complicated With Internal Fistulizing Disease: BIOSCOPE Study From GETECCU (C) The American College of Gastroenterology 2023. All Rights Reserved.
American Gastroenterological Association-American College of Gastroenterology Clinical Practice Guideline: Pharmacological Management of Chronic Idiopathic Constipation.
Chang, Lin MD, AGAF, FACG 1,*; Chey, William D. MD, FACG 2,*; Imdad, Aamer MBBS, MPH 3,*; Almario, Christopher V. MD, MSHPM, FACG 4; Bharucha, Adil E. MD 5; Diem, Susan MD, MPH 6,7; Greer, Katarina B. MD, MS Epi 8,9; Hanson, Brian MD 6,10; Harris, Lucinda A. MD, FACG 11; Ko, Cynthia MD 12; Murad, M. Hassan MD 13; Patel, Amit MD, FACG 14; Shah, Eric D. MD, MBA, FACG 2,15; Lembo, Anthony J. MD, FACG 16,+; Sultan, Shahnaz MD, MHSc, FACG 6,17,+
doi : 10.14309/ajg.0000000000002227
Chronic idiopathic constipation (CIC) is a common disorder associated with significant impairment in quality of life. This clinical practice guideline, jointly developed by the American Gastroenterological Association and the American College of Gastroenterology, aims to inform clinicians and patients by providing evidence-based practice recommendations for the pharmacological treatment of CIC in adults
A Review of the Cardiovascular Safety of Prucalopride in Patients With Chronic Idiopathic Constipation.
Tack, Jan MD, PhD 1; Derakhchan, Katayoun PhD, DSP 2; Gabriel, Andre MD, MS 3; Spalding, William MS 3; Terreri, Brian PharmD, MBA 4; Youssef, Ashraf MD, PhD, DABT, MBA 2; Kreidieh, Bahij MD 5; Kowey, Peter R. MD 5; Boules, Mena MD 4
doi : 10.14309/ajg.0000000000002249
AB Prokinetic agents, specifically 5-hydroxytryptamine type 4 (5-HT4) receptor agonists, have been shown to provide relief in chronic idiopathic constipation (CIC). The first-generation 5-HT4 agonists were initially withdrawn from use owing to associations with serious cardiovascular (CV) events.
Ultrasonographic Transmural Healing in Crohn's Disease.
Zorzi, Francesca MD, PhD 1; Rubin, David T. MD, FACG 2; Cleveland, Noa Krugliak MD 2; Monteleone, Giovanni MD, PhD 1; Calabrese, Emma MD, PhD 1
doi : 10.14309/ajg.0000000000002265
AB Therapeutic targets in Crohn's disease (CD) have evolved greatly over the past several decades to include endoscopic improvement along with clinical remission.
Patients With Compensated Hepatitis B Virus-Related Cirrhosis and Low-Level Viremia: Treat or Not to Treat?.
Ghany, Marc G. MD, MHSc 1; Saraswat, Vivek A. MD, DM, FACG, FINASL, MISG, FSGEI 2
doi : 10.14309/ajg.0000000000002224
AB Patients with hepatitis B virus-related cirrhosis and low-level viremia represent a special group that might benefit from treatment because of their higher risk of complications. Evidence for the benefit of treatment in this population is lacking.
Transpapillary Stenting Improves Treatment Outcomes in Patients Undergoing Endoscopic Transmural Drainage of Ductal Disruption-Associated Pancreatic Fluid Collections.
Ni, Jianbo MD 1,2,*; Peng, Kui MD 1,*; Yu, Lanting PhD 1,2,*; Xie, Haoran MS 1,2; Luo, Shengzheng MD 1; Xu, Kai MS 1; Xia, Youchen MD 1; Xie, Ni MS 1,2; Lu, Jiawei MS 1,2; Lu, Lungen MD 1; Hu, Duanmin MD 3; Wan, Xinjian MD 4; Li, Baiwen MD 1,2
doi : 10.14309/ajg.0000000000002083
Endoscopic transmural drainage (TMD) has been accepted as the preferred therapy for symptomatic pancreatic fluid collections (PFCs). Recurrence of PFCs presents a unique challenge in patients with disrupted pancreatic duct (PD).
Regression of Hepatic Fibrosis After Endoscopic Gastric Plication in Nonalcoholic Fatty Liver Disease.
Jirapinyo, Pichamol MD, MPH 1,2; Zucker, Stephen D. MD 1,2; Thompson, Christopher C. MD, MSc 1,2
doi : 10.14309/ajg.0000000000002087
Fibrosis stage is the strongest predictor of mortality in patients with nonalcoholic fatty liver disease (NAFLD). There is currently no approved therapy that specifically targets fibrosis.
Results of a Model of Delivering Hepatitis C Care in a Homeless Metropolitan Population in England.
Guerra-Veloz, Maria Fernanda MD, PhD 1; Han, Khin MD 1; Oakes, Kathryn CNS 1; Robertson, David CNS 1; Mohamed, Almuthana MD 1; Cannon, Mary MB, PhD 1; Barnabas, Ashley MB 1; Shah, Sital PhD 1; Halford, Rachel PhD 2; Dusheiko, Geoffrey MB, PhD 1; Agarwal, Kosh MD, FRCP 1
doi : 10.14309/ajg.0000000000002041
Given the hepatitis C virus (HCV) burden and despite curative treatments, more efforts focused on scaling-up testing and treatment in homeless populations are needed.
Comparable Mortality Between Asian Patients with Chronic Hepatitis B Under Long-Term Antiviral Therapy vs Matched Control: A Population-Based Study.
Yun, Byungyoon MD 1,*; Oh, Juyeon BSc 2,*; Ahn, Sang Hoon MD, PhD 3,4,5; Yoon, Jin-Ha MD, PhD 1,6; Kim, Beom Kyung MD, PhD 3,4,5
doi : 10.14309/ajg.0000000000002074
Antiviral therapy (AVT) substantially improved the prognosis for patients with chronic hepatitis B (CHB). Head-to-head comparisons of prognosis between treated patients with CHB and the general population are scarce.
Low Level of Hepatitis B Viremia Compared With Undetectable Viremia Increases the Risk of Hepatocellular Carcinoma in Patients With Untreated Compensated Cirrhosis.
Yang, Jiwon MD, MS 1; Choi, Won-Mook MD, PhD 1; Shim, Ju Hyun MD, PhD 1; Lee, Danbi MD, PhD 1; Kim, Kang Mo MD, PhD 1; Lim, Young-Suk MD, PhD 1; Lee, Han Chu MD, PhD 1; Choi, Jonggi MD, PhD 1
doi : 10.14309/ajg.0000000000002181
The initiation of antiviral treatment in patients with chronic hepatitis B with compensated cirrhosis and low-level viremia (LLV; HBV DNA 15-2,000 IU/mL) remains controversial.
Patency Capsule: A Novel Independent Predictor for Long-Term Outcomes Among Patients With Quiescent Crohn's Disease.
Ukashi, Offir MD 1,2; Kopylov, Uri MD 1; Ungar, Bella MD 1; Haj-Natour, Ola RN 1; Selinger, Limor BA 1; Neuman, Sandra RN 1; Yanai, Henit MD 3; Dotan, Iris MD 3; Yablecovitch, Doron MD 1; Lahat, Adi MD 1; Eliakim, Rami MD 1; Ben-Horin, Shomron MD 1; for the Israeli IBD Research Nucleus (IIRN)
doi : 10.14309/ajg.0000000000002118
Patency capsule (PC) is a recommended procedure to rule out small bowel stenosis before video capsule endoscopy (VCE). We examined future clinical outcomes among patients with a failed PC vs patients in whom the PC had passed (passed PC).
Serum Leucine-Rich [alpha]2 Glycoprotein: A Novel Biomarker for Transmural Inflammation in Crohn's Disease.
Takenaka, Kento MD, PhD 1; Kitazume, Yoshio PhD 2; Kawamoto, Ami PhD 1; Fujii, Toshimitsu PhD 1; Udagawa, Yumi MS 3; Wanatabe, Ryosuke PhD 2; Shimizu, Hiromichi PhD 1; Hibiya, Shuji PhD 1; Nagahori, Masakazu PhD 1; Ohtsuka, Kazuo PhD 4; Sato, Hiroyuki PhD 5; Hirakawa, Akihiro PhD 5; Watanabe, Mamoru PhD 6; Okamoto, Ryuichi PhD 1
doi : 10.14309/ajg.0000000000002127
Leucine-rich alpha-2 glycoprotein (LRG) is a newly studied biomarker for inflammatory diseases. This study aimed to investigate whether LRG can be used for evaluating transmural activity in patients with Crohn's disease (CD).
Long-Term Outcomes of Biological Therapy in Crohn's Disease Complicated With Internal Fistulizing Disease: BIOSCOPE Study From GETECCU.
Barreiro-de Acosta, Manuel MD, PhD 1; Fernandez-Clotet, Agnes MD 2,3; Mesonero, Francisco MD 4; Garcia-Alonso, Francisco Javier MD, PhD 5; Casanova, Maria Jose MD, PhD 3,6; Fernandez-de la Varga, Margarita MD 7; Canete, Fiorella MD 3,8; de Castro, Luisa MD, PhD 9; Gutierrez, Ana MD, PhD 3,10; Sicilia,
doi : 10.14309/ajg.0000000000002152
The prevalence of penetrating complications in Crohn's disease (CD) increases progressively over time, but evidence on the medical treatment in this setting is limited.
Normative Values for Body Surface Gastric Mapping Evaluations of Gastric Motility Using Gastric Alimetry: Spectral Analysis.
Varghese, Chris MBChB, BMedSc(Hons) 1,*; Schamberg, Gabriel PhD 1,2,*; Calder, Stefan PhD 1,2; Waite, Stephen PhD 2; Carson, Daniel MBChB, BMedSc(Hons) 1; Foong, Daphne PhD 3; Wang, William Jiaen MBBS 3; Ho, Vincent MBBS, Bsc(Med), MMed (Clin Epi), FRACP, FACP, PhD 3; Woodhead, Jonathan PhD 2; Daker, Charlotte MBBS 2; Xu, William MBChB, BMedSc(Hons) 1; Du, Peng PhD 2,4; Abell, Thomas L. MD 5; Parkman, Henry P. MD 6; Tack, Jan MD, PhD 7; Andrews, Christopher N. MD, MSc, FRCPC 8; O'Grady, Gregory BhB, MBChB, PhD, FRACS 1,2,4; Gharibans, Armen A. PhD 1,2,4
doi : 10.14309/ajg.0000000000002077
Body surface gastric mapping (BSGM) is a new noninvasive test of gastric function. BSGM offers several novel and improved biomarkers of gastric function capable of differentiating patients with overlapping symptom profiles. The aim of this study was to define normative reference intervals for BSGM spectral metrics in a population of healthy controls.
Consumption of 2 Green Kiwifruits Daily Improves Constipation and Abdominal Comfort-Results of an International Multicenter Randomized Controlled Trial.
Gearry, Richard MD, PhD *,1; Fukudo, Shin MD, PhD *,2,3; Barbara, Giovanni MD *,4; Kuhn-Sherlock, Barbara PhD 5; Ansell, Juliet PhD 6; Blatchford, Paul PhD 6; Eady, Sarah MSc 7; Wallace, Alison PhD 7; Butts, Christine PhD 7; Cremon, Cesare MD 4; Barbaro, Maria Raffaella PhD 4; Pagano, Isabella MD 4; Okawa, Yohei PhD 2; Muratubaki, Tomohiko PhD 2; Okamoto, Tomoko PhD 8; Fuda, Mikiko MS 9; Endo, Yuka MD 3; Kano, Michiko MD, PhD 2; Kanazawa, Motoyori MD, PhD 2,3; Nakaya, Naoki PhD 10; Nakaya, Kumi PhD 10; Drummond, Lynley BTech (Hons) 11
doi : 10.14309/ajg.0000000000002124
Consumption of green kiwifruit is known to relieve constipation. Previous studies have also reported improvements in gastrointestinal (GI) comfort.
Epidemiology and Economic Burden of Acute Infectious Gastroenteritis Among Adults Treated in Outpatient Settings in US Health Systems.
Moon, Rena C. MD, MPH 1; Bleak, Tammy C. PharmD, MSc 2; Rosenthal, Ning A. PhD, MD, MPH 1; Couturier, Brianne PhD 2; Hemmert, Rachael MSPH 2; Timbrook, Tristan T. PharmD, MBA 2; Brown, Harold MHA, MBA 1; Fang, Ferric C. MD 3
doi : 10.14309/ajg.0000000000002186
Acute infectious gastroenteritis (AGE) is a common reason for outpatient visits and hospitalizations in the United States. This study aimed to understand the demographic and clinical characteristics, common pathogens detected, health care resource utilization (HRU), and cost among adult outpatients with AGE visiting US health systems
High Triglyceride Variability Increases the Risk of First Attack of Acute Pancreatitis.
Tung, Ying-Chang MD 1,2; Hsiao, Fu-Chih MD 1; Lin, Chia-Pin MD 1; Ho, Chien-Te MD 1; Hsu, Tzyy-Jer MD 1; Chiang, Hou-Yu PhD 1,3,4; Chu, Pao-Hsien MD 1,2
doi : 10.14309/ajg.0000000000002198
Hypertriglyceridemia is the third most common etiology of acute pancreatitis. Whether triglyceride variability, independent of absolute triglyceride levels, is a predictor of acute pancreatitis is unknown.
Quality Indicators for the Diagnosis and Management of Eosinophilic Esophagitis.
Leiman, David A. MD, MSHP 1,2; Kamal, Afrin N. MD, MS 3; Otaki, Fouad MD 4; Bredenoord, Albert J. MD, PhD 5; Dellon, Evan S. MD, MPH 6; Falk, Gary W. MD, MSc 7; Fernandez-Becker, Nielsen Q. MD, PhD 3; Gonsalves, Nirmala MD 8; Hirano, Ikuo MD 8; Katzka, David A. MD 9; Peterson, Kathryn MD, MSci 10; Yadlapati, Rena MD, MS 11; Kathpalia, Priya MD 12
doi : 10.14309/ajg.0000000000002138
Despite best practice recommendations for managing eosinophilic esophagitis (EoE), variation in care exists. METHODS: We used established methodology for quality indicator development to identify metrics to define quality for the treatment of EoE
Low Risk of Lymphoma in Pediatric Patients Treated for Inflammatory Bowel Disease: Need More Evidence.
Hu, Fei-Hong MM 1; Chen, Hong-Lin MD 2
Comment on the 2023 ACG Guideline for Celiac Disease.
Husby, Steffen MD, DMSc 1; Murrary, Joseph MD 2
Response to Rettally and Husby and Murray.
Rubio-Tapia, Alberto MD 1; Greer, Katarina B. MD, MS 2; Limketkai, Berkeley N. MD, PhD, FACG 3; Hill, Ivor D. MD 4; Semrad, Carol MD 5; Kelly, Ciaran P. MD 6; Lebwohl, Benjamin MD, MS 7
Evaluating a Novel, Portable, Self-Administrable Device ("Beacon") That Measures Critical Flicker Frequency as a Test for Hepatic Encephalopathy.
Vutien, Philip MD, MS 1,2,*; Li, Richard PhD candidate 3,*; Karkar, Ravi PhD 4,3; Munson, Sean A. PhD 5; Fogarty, James PhD 3; Walter, Kara MD 1; Yacoub, Michael BS 1; Ioannou, George N. BMBCh, MS 1,2
doi : 10.14309/ajg.0000000000002211
We compared critical flicker frequency (CFF) thresholds obtained using a novel portable device "Beacon" with thresholds from the commercially available Lafayette Flicker Fusion System (Lafayette-FFS) in patients with cirrhosis.
