دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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Comparative effectiveness of stent-assisted coiling and Woven EndoBridge embolization for the treatment of unruptured wide-neck bifurcation intracranial aneurysms
Ahmed Kashkoush MD , Mohamed E. El-Abtah BA , Shaarada Srivatsa MD , Ansh Desai BA , Mark Davison MD , Rebecca Achey MD , Ashutosh Mahapatra MD , Thomas Patterson PhD , Nina Moore MD , and Mark Bain MD
doi : 10.3171/2022.10.JNS221138
Volume 138: Issue 6 (Jun 2023)
Woven EndoBridge (WEB) intrasaccular flow disruptors and stent-assisted coiling (SAC) are viable endovascular treatment options for wide-neck bifurcation intracranial aneurysms (WNBAs).
Middle meningeal artery embolization for treatment of chronic subdural hematomas: does selection of embolized branches affect outcomes?
MirHojjat Khorasanizadeh MD , Max Shutran MD , Alfonso Garcia MPH , Alejandro Enriquez-Marulanda MD , Justin Moore MD, PhD , Christopher S. Ogilvy MD , and Ajith J. Thomas MD
doi : 10.3171/2022.9.JNS221663
Middle meningeal artery (MMA) embolization (MMAE) is a new therapeutic modality for chronic subdural hematoma (cSDH). There is limited evidence comparing various MMAE procedural techniques, resulting in significant variations in technique and procedural planning. The objective of this study was to compare outcomes of MMAE by the number and location of MMA branches that were embolized.
Periprocedural cerebrovascular complications and 30-day outcomes of endovascular treatment for intracranial vertebral artery dissecting aneurysms
Jiangli Han MD , Fei Liu MD , Jigang Chen MD , Xin Tong MD , Mingyang Han MD , Fei Peng MD , Hao Niu MS , Lang Liu MS , and Aihua Liu MD
doi : 10.3171/2022.10.JNS221953
The authors undertook an evaluation of periprocedural cerebrovascular complications and 30-day outcomes of endovascular treatment for intracranial vertebral artery dissecting aneurysms (IVADAs) and assessed the relevant risk factors.
Alteration of default mode network: association with executive dysfunction in frontal glioma patients
Xiaokang Zhang MD , Guobin Zhang MD , Yonggang Wang MD , Huawei Huang MD , Haoyi Li MM , Mingxiao Li MD , Chuanwei Yang MD , Ming Li MM , Hongyan Chen MD , Bin Jing PhD , and Song Lin MD
doi : 10.3171/2022.8.JNS22591
Patients with frontal gliomas often experience executive dysfunction (EF-D) before surgery, and the changes in brain plasticity underlying this effect remain obscure. In this study, the authors aimed to assess whole-brain structural and functional alterations by using structural MRI and resting-state functional MRI (rs-fMRI) in frontal glioma patients with or without EF-D.
A national stratification of the global macroeconomic burden of central nervous system cancer
Jakob V. E. Gerstl MBBS , Alexander G. Yearley BA , John L. Kilgallon BA , Philipp Lassarén BSc , Faith C. Robertson MD, MSc , Vendela Herdell , Andy Y. Wang AB , David J. Segar MD , Joshua D. Bernstock MD, PhD , Edward R. Laws MD , Kavitha Ranganathan MD , and Timothy R. Smith MD, PhD, MPH
doi : 10.3171/2022.9.JNS221499
Country-by-country estimates of the macroeconomic disease burden of central nervous system (CNS) cancers are important when determining the allocation of resources related to neuro-oncology. Accordingly, in this study the authors investigated macroeconomic losses related to CNS cancer in 173 countries and identified pertinent epidemiological trends.
Precuneal gliomas promote behaviorally relevant remodeling of the functional connectome
Sam Ng MD , Jeremy Deverdun PhD , Anne-Laure Lemaitre PhD , Davide Giampiccolo MD , Emmanuelle Le Bars PhD , Sylvie Moritz-Gasser PhD , Nicolas Menjot de Champfleur MD, PhD , Hugues Duffau MD, PhD , and Guillaume Herbet PhD
doi : 10.3171/2022.9.JNS221723
The precuneus hosts one of the most complex patterns of functional connectivity in the human brain. However, due to the extreme rarity of neurological lesions specifically targeting this structure, it remains unknown how focal damage to the precuneus may impact resting-state functional connectivity (rsFC) at the brainwide level.
Long-term postoperative health-related quality of life in patients with subfrontal meningiomas
Emma Kofoed Lauridsen MD , Urszula Maria Ciochon MD , Anders Tolver PhD , Mark Bech Knudsen BS , Laura Giraldi PhD , Jacob Bertram Springborg PhD , Lars Bøgeskov MD , Lars Poulsgaard MD , Tiit Mathiesen PhD , Karin Piil PhD , and Kåre Fugleholm PhD
doi : 10.3171/2022.9.JNS22826
Subfrontal meningiomas grow insidiously in areas with high cerebral compliance and a relative scarcity of eloquent function. Symptoms develop progressively, are nonspecific, and include anosmia, changes in personality and cognition, depressive symptoms, headaches, visual disturbances, and seizures.
Multidisciplinary management of patients with non–small cell lung cancer with leptomeningeal metastasis in the tyrosine kinase inhibitor era
Kuan-Yu Chen  MD , Shang-Gin Wu  MD, PhD , Dar-Ming Lai  MD, PhD , Lu-Ting Kuo  MD, PhD , and Abel Po-Hao Huang  MD, PhD
doi : 10.3171/2022.8.JNS221175
Leptomeningeal metastasis (LM) is a challenging scenario in non–small cell lung cancer (NSCLC). Considering that outcomes of treatment modalities stratified by LM chronological patterns related to brain metastasis (BM) are lacking, the aim of this study was to evaluate outcomes and explore prognostic factors.
Predicting leptomeningeal disease spread after resection of brain metastases using machine learning
Ishaan Ashwini Tewarie MD , Alexander W. Senko PhD , Charissa A. C. Jessurun MD , Abigail Tianai Zhang BS , Alexander F. C. Hulsbergen MD , Luis Rendon MD , Jack McNulty MD , Marike L. D. Broekman MD, PhD, LLM , Luke C. Peng MD, MS , Timothy R. Smith MD, PhD, MPH , and John G. Phillips MD, MPH
doi : 10.3171/2022.8.JNS22744
The incidence of leptomeningeal disease (LMD) has increased as treatments for brain metastases (BMs) have improved and patients with metastatic disease are living longer.
Intranasal delivery of nanoliposomal SN-38 for treatment of diffuse midline glioma
Takahiro Sasaki MD, PhD , Jun Watanabe MD, PhD , Xingyao He MS , Hiroaki Katagi MD, PhD , Amreena Suri MPH , Yukitomo Ishi MD, PhD , Kouki Abe PhD , Manabu Natsumeda MD, PhD , William H. Frey II PhD , Peng Zhang PhD , and Rintaro Hashizume MD, PhD
doi : 10.3171/2022.9.JNS22715
Diffuse midline gliomas, including diffuse intrinsic pontine gliomas (DIPGs), are among the most malignant and devastating childhood brain cancers. Despite aggressive treatment, nearly all children with these tumors succumb to their disease within 2 years of diagnosis.
Factors associated with radiation toxicity and long-term tumor control more than 10 years after Gamma Knife surgery for non–skull base, nonperioptic benign supratentorial meningiomas
Eun Jung Lee  MD, PhD , Hyun-Tai Chung  PhD , Hangeul Park  MD , Jin-Wook Kim  MD, PhD , Dong Gyu Kim  MD, PhD , and Sun Ha Paek  MD, PhD
doi : 10.3171/2022.8.JNS22422
Gamma Knife surgery (GKS) is a well-established treatment for benign intracranial meningiomas; however, the dosimetric factors associated with long-term GKS efficacy and safety remain to be elucidated.
Effectiveness of immune checkpoint inhibitors in combination with stereotactic radiosurgery for patients with brain metastases from renal cell carcinoma: inverse probability of treatment weighting using propensity scores
Shoji Yomo MD, PhD , Kyota Oda MD , and Kazuhiro Oguchi MD
doi : 10.3171/2022.9.JNS221215
Stereotactic radiosurgery (SRS) is the mainstay for treating brain metastases (BMs) from renal cell carcinoma (RCC). In recent years, immune checkpoint inhibitors (ICIs) have been applied to metastatic RCC and have contributed to improved outcomes.
Clinical outcomes of non–small cell lung cancer brain metastases treated with stereotactic radiosurgery and immune checkpoint inhibitors, EGFR tyrosine kinase inhibitors, chemotherapy and immune checkpoint inhibitors, or chemotherapy alone
Ammoren E. Dohm  MD , Joseph D. Tang  BA , Matthew N. Mills  MD , Casey L. Liveringhouse  MD , Maria L. Sandoval  MD, MS , Bradford A. Perez  MD , Timothy J. Robinson  MD, PhD , Benjamin C. Creelan  MD , Jhanelle E. Gray  MD , Arnold B. Etame  MD, PhD , Michael A. Vogelbaum  MD, PhD , Peter Forsyth  MD , Hsiang-Hsuan Michael Yu  MD, ScM , Daniel E. Oliver  MD , and Kamran A. Ahmed  MD
doi : 10.3171/2022.9.JNS221896
Immune checkpoint inhibitors (ICIs) and epidermal growth factor receptor–tyrosine kinase inhibitors (EGFR-TKIs) are commonly used in the systemic management of non–small cell lung cancer (NSCLC) brain metastases (BMs). However, optimizing control of NSCLC BM with stereotactic radiosurgery (SRS) and various systemic therapies remains an area of investigation.
Stereotactic radiosurgery and local control of brain metastases from triple-negative breast cancer
Roman O. Kowalchuk MD , Ajay Niranjan MD, MBA , Judith Hess BA , Joseph P. Antonios MD, PhD , Michael Y. Zhang MD, PhD , Steve Braunstein MD, PhD , Richard B. Ross MD , Stylianos Pikis MD , Christopher P. Deibert MD , Cheng-chia Lee MD, PhD , Huai-che Yang MD , Anne-Marie Langlois MD , David Mathieu MD , Selcuk Peker MD , Yavuz Samanci MD , Chad G. Rusthoven MD , Veronica Chiang MD , Zhishuo Wei MSc , L. Dade Lunsford MD , Daniel M. Trifiletti MD , and Jason P. Sheehan MD, PhD
doi : 10.3171/2022.10.JNS221900
Stereotactic radiosurgery (SRS) is an effective treatment for intracranial metastatic disease, but its role in triple-negative breast cancer requires further study. Herein, the authors report overall survival (OS) and local tumor control in a multiinstitutional cohort with triple-negative breast cancer metastases treated with SRS.
Long-term follow-up of an overexposure radiation incident in a cohort treated with linear accelerator–based stereotactic radiosurgery for intracranial arteriovenous malformations
Pierre-Yves Borius  MD, PhD , Anne Christine Januel  MD , Jean Yves Plas  MD , Pierre Duthil  PhD , Jean Albert Lotterie  MD, PhD , Igor Latorzeff  MD, PhD , and Jean Sabatier  MD, PhD
doi : 10.3171/2022.10.JNS221763
Dosimetric radiosurgery incidents are rare and probably insufficiently reported in scientific publications. After a long follow-up (FU), the authors studied the outcomes of patients treated with overexposure radiation for arteriovenous malformation (AVM) administered via stereotactic radiosurgery (SRS) at their department.
Stereotactic radiosurgery for orbital cavernous hemangiomas
You-Cong Chen MD , Chieh-Chih Tsai MD, PhD , Shih-Jen Chen MD, PhD , Hsiu-Mei Wu MD , Huai-Che Yang MD, PhD , Ching-Jen Chen MD , Yong-Sin Hu MD , Chung-Jung Lin MD , Wan-Yuo Guo MD, PhD , David Hung-Chi Pan MD , Wen-Yuh Chung MD , and Cheng-Chia Lee MD, PhD
doi : 10.3171/2022.8.JNS221222
The goal of this study was to assess the safety and efficacy of single-session Gamma Knife radiosurgery (GKRS) for orbital cavernous hemangiomas (OCHs).
Surgical management of large cerebellopontine angle meningiomas: long-term results of a less aggressive resection strategy
Lucas Troude MD , Valentin Avinens MD , Kaissar Farah MD , Mohamed Boucekine PhD , Anne Balossier MD , Jean Regis MD , Guillaume Baucher MD , and Pierre-Hugues Roche MD
doi : 10.3171/2022.8.JNS221329
Cerebellopontine angle (CPA) meningiomas present many surgical challenges depending on their volume, site of dural attachment, and connection to surrounding neurovascular structures.
Management strategies in clival and craniovertebral junction chordomas: a 29-year experience
Thibault Passeri MD , Pierre-Olivier Champagne MD, PhD , Lorenzo Giammattei MD , Rosaria Abbritti MD , Jérôme Cartailler PhD , Valentin Calugaru MD, PhD , Loïc Feuvret MD , Jean-Pierre Guichard MD , Marc Polivka MD , Homa Adle-Biassette MD, PhD , Hamid Mammar MD, PhD , Damien Bresson MD, PhD , Philippe Herman MD, PhD , Emmanuel Mandonnet MD, PhD , Bernard George MD , and Sébastien Froelich MD
doi : 10.3171/2022.8.JNS221621
Chordomas represent one of the most challenging subsets of skull base and craniovertebral junction (CVJ) tumors to treat. Despite extensive resection followed by proton-beam radiation therapy, the recurrence rate remains high, highlighting the importance of developing efficient treatment strategies. In this study, the authors present their experience in treating clival and CVJ chordomas over a 29-year period.
Indications and outcomes of endoscopic transorbital surgery for trigeminal schwannoma based on tumor classification: a multicenter study with 50 cases
Doo-Sik Kong MD, PhD , Yong Hwy Kim MD, PhD , Won-Jae Lee MD, PhD , Young-Hoon Kim MD, PhD , and Chang-Ki Hong MD, PhD
doi : 10.3171/2022.9.JNS22779
Trigeminal schwannoma is a rare CNS tumor and involves the multicompartmental skull base. Recently, the endoscopic transorbital approach (ETOA) has emerged as a technique for minimally invasive surgery. The objective of this study was to evaluate the optimal indications and clinical outcomes of the ETOA for trigeminal schwannomas based on their tumor classification.
Adjuvant versus on-progression Gamma Knife radiosurgery for residual nonfunctioning pituitary adenomas: a matched-cohort analysis
Georgios Mantziaris MD , Stylianos Pikis MD , Tomas Chytka MD , Roman Liš�ák MD , Kimball Sheehan , Darrah Sheehan , Selcuk Peker MD , Yavuz Samanci MD , Shray K. Bindal BA , Ajay Niranjan MD, MBA , L. Dade Lunsford MD , Rupinder Kaur MD , Renu Madan MD , Manjul Tripathi MCh , Dhiraj J. Pangal BS , Ben A. Strickland MD , Gabriel Zada MD, MS , Anne-Marie Langlois MD , David Mathieu MD , Ronald E. Warnick MD , Samir Patel MD , Zayda Minier MD , Herwin Speckter MD , Zhiyuan Xu MD , Rithika Kormath Anand , and Jason P. Sheehan MD, PhD
doi : 10.3171/2022.10.JNS221873
Radiological progression occurs in 50%–60% of residual nonfunctioning pituitary adenomas (NFPAs). Stereotactic radiosurgery (SRS) is a safe and effective management option for residual NFPAs, but there is no consensus on its optimal timing. This study aims to define the optimal timing of SRS for residual NFPAs.
Correlation between tumor volume and serum prolactin and its effect on surgical outcomes in a cohort of 219 prolactinoma patients
Robert C. Osorio BS , Matheus P. Pereira MD , Taemin Oh MD , Rushikesh S. Joshi MD , Alexander F. Haddad MD , Kaitlyn M. Pereira MD , Kevin C. Donohue BS , Zain Peeran BS , William Carson , Aarav Badani , Elaina J. Wang MD , Sweta Sudhir BS , Ankush Chandra MD , Saket Jain PhD , Angad Beniwal BS , José Gurrola II MD , Ivan H. El-Sayed MD , Lewis S. Blevins Jr. MD , Philip V. Theodosopoulos MD , Sandeep Kunwar MD , and Manish K. Aghi MD, PhD
doi : 10.3171/2022.8.JNS221890
Prolactinoma is the most common pituitary adenoma and can be managed medically or surgically. The authors assessed the correlation between tumor volume and prolactin level and its effect on surgical outcomes.
Phase II trial of icotinib in adult patients with neurofibromatosis type 2 and progressive vestibular schwannoma
Fu Zhao MD, PhD , Shi-wei Li MD , Shun Zhang MD , Peng Li MD , Chi Zhao MD , Xiao-bin Zhao MD, PhD , Chun-Hong Wang MD , Jing Zhang BE , Bo Wang MD , and Pi-nan Liu MD, PhD
doi : 10.3171/2022.9.JNS22699
Neurofibromatosis type 2 (NF2) is a rare autosomal dominant syndrome associated primarily with bilateral vestibular schwannomas (VSs). Conventional surgical or radiosurgical treatments for VS in NF2 usually result in high risks of hearing loss and facial nerve impairment, while there is no validated medical option to date
Deep brain stimulation for movement disorders after stroke: a systematic review of the literature
Mitch R. Paro BA , Michal Dyrda BS , Srinath Ramanan BS , Grant Wadman , Stacey-Ann Burke , Isabella Cipollone BS , Cory Bosworth MBA , Sarah Zurek RN, BSN , and Patrick B. Senatus MD, PhD
doi : 10.3171/2022.8.JNS221334
Stroke remains the leading cause of disability in the United States. Even as acute care for strokes advances, there are limited options for improving function once the patient reaches the subacute and chronic stages. Identification of new therapeutic approaches is critical. Deep brain stimulation (DBS) holds promise for these patients
Accuracy, precision, and safety of stereotactic, frame-based, intraoperative MRI-guided and MRI-verified deep brain stimulation in 650 consecutive procedures
Ali Rajabian FEBNS(Neurosurgery) , Saman Vinke PhD , Joseph Candelario-Mckeown MSc , Catherine Milabo BN , Maricel Salazar BN , Abdul Karim Nizam BSc(Hons) , Nadia Salloum MBChB , Jonathan Hyam PhD , Harith Akram PhD , Eileen Joyce PhD , Thomas Foltynie PhD , Patricia Limousin PhD , Marwan Hariz MD, PhD , and Ludvic Zrinzo PhD
doi : 10.3171/2022.8.JNS22968
Suboptimal lead placement is one of the most common indications for deep brain stimulation (DBS) revision procedures. Confirming lead placement in relation to the visible anatomical target with dedicated stereotactic imaging before terminating the procedure can mitigate this risk.
Altered brain network centrality in Parkinson’s disease patients after deep brain stimulation: a functional MRI study using a voxel-wise degree centrality approach
Bei Luo  MS , Chang Qiu  MS , Lei Chang  MS , Yue Lu  MS , Wenwen Dong  MD , Dongming Liu  MD , Chen Xue  MS , Jun Yan  MD , and Wenbin Zhang  MD
doi : 10.3171/2022.9.JNS221640
After deep brain stimulation (DBS), patients with Parkinson’s disease (PD) show improved motor symptoms and decreased verbal fluency, an effect that occurs before the initiation of DBS in the subthalamic nucleus. However, the underlying mechanism remains unclear. This study aimed to evaluate the effects of DBS on whole-brain degree centrality (DC) and seed-based functional connectivity (FC) in PD patients.
Is intracranial electroencephalography mandatory for MRI-negative neocortical epilepsy surgery?
Zhihao Guo MD , Chao Zhang MD , Xiu Wang MD , Chang Liu MD , Baotian Zhao MD , Jiajie Mo MD , Zhong Zheng MD , Xiaoqiu Shao MD , Jianguo Zhang MD , Kai Zhang MD , and Wenhan Hu MD
doi : 10.3171/2022.8.JNS22995
MRI-negative focal epilepsy is one of the most challenging cases in surgical epilepsy treatment. Many epilepsy centers recommend intracranial electroencephalography (EEG) for MRI-negative cases, especially neocortical epilepsy.
Characterization of patients with idiopathic normal pressure hydrocephalus using natural language processing within an electronic healthcare record system
Jonathan P. Funnell MBBS , Kawsar Noor , Danyal Z. Khan MRCS , Linda D’Antona MBBS, MD , Richard J. B. Dobson PhD , John G. Hanrahan MBBS , Christopher Hepworth PhD , Eleanor M. Moncur MBChB , Benjamin M. Thomas BSc , Lewis Thorne FRCS(SN) , Laurence D. Watkins FRCS(SN), MD , Simon C. Williams MBChB , Wai Keong Wong FRCPath, MRCP, PhD , Ahmed K. Toma FRCS(SN), MD , and Hani J. Marcus FRCS(SN), PhD
doi : 10.3171/2022.9.JNS221095
Idiopathic normal pressure hydrocephalus (iNPH) is an underdiagnosed, progressive, and disabling condition. Early treatment is associated with better outcomes and improved quality of life.
Surgical instruments and catheter damage during ventriculoperitoneal shunt assembly
Wilson A. M. Fisher MSc , Michael P. Catalino MD, MSc , E. Alice Woolard BS , Bethany J. Andrews MD , Scott Elton MD , and Carolyn Quinsey MD
doi : 10.3171/2022.8.JNS22746
Current surgical techniques use common surgical instruments for sterile shunt assembly. This study investigated the impact of using these techniques and surgical instruments on the mechanical integrity of the ventriculoperitoneal shunt system, specifically shunt catheters.
Continued underrepresentation of historically excluded groups in the neurosurgery pipeline: an analysis of racial and ethnic trends across stages of medical training from 2012 to 2020
Elijah M. Persad-Paisley BA , Sarah B. Andrea PhD, MPH , Owen P. Leary BS , Orianna D. Carvalho MA , Victoria G. Zeyl BA , Amanda R. Laguna BS , Matthew N. Anderson MD , Belinda Shao MD, MPH , Steven A. Toms MD, MPH , Adetokunbo A. Oyelese MD, PhD , Ziya L. Gokaslan MD , and Katherine M. Sharkey MD, PhD
doi : 10.3171/2022.8.JNS221143
US allopathic medical schools have experienced improvements in racial and ethnic diversity among matriculants in the past decade. It is not clear, however, whether better representation of historically excluded racial and ethnic groups at medical school entry impacts subsequent stages of the medical training pipeline leading into a specific field.
Best practices for the pregnant neurosurgical resident: balancing safety and education
Krystal L. Tomei MD, MPH , Tiffany R. Hodges MD , Ellie Ragsdale MD , Tyler Katz MD , Marjorie Greenfield MD , and Jennifer A. Sweet MD
doi : 10.3171/2022.9.JNS221727
Establishment of a diverse neurosurgical workforce includes increasing the recruitment of women in neurosurgery. The impact of pregnancy on the training and career trajectory of female neurosurgeons poses a barrier to recruitment and retention of women in neurosurgery.
Pursuing perfect 2D and 3D photography in neuroanatomy: a new paradigm for staying up to date with digital technology
Yuanzhi Xu MD , Vera Vigo MD , Joshua Klein MSMI , Maximiliano Alberto Nunez MD , Juan C. Fernandez-Miranda MD , Aaron A. Cohen-Gadol MD, MSc, MBA , and Ying Mao MD
doi : 10.3171/2022.9.JNS221988
Promoting diversity in neurosurgery: a multi-institutional scholarship-based approach
Mareshah N. Sowah MS , Anthony T. Fuller MD, MScGH , Stephanie H. Chen MD , Barth A. Green MD , Michael E. Ivan MD, MBS , Henri R. Ford MD , Gregory J. Zipfel MD , Brenton Pennicooke MD, MS , Nicholas Theodore MD, MS , and Allan D. Levi MD, PhD
doi : 10.3171/2023.1.JNS221853
Letter to the Editor. Management of residual nonfunctioning pituitary adenoma: watchful waiting or adjuvant treatment?
Luigi Albano MD, PhD , Marco Losa MD , Lina Raffaella Barzaghi MD , and Pietro Mortini MD
doi : 10.3171/2023.1.JNS2312
