Moiz, Areesha BSc; Eisenberg, Mark J. MD, MPH
doi : 10.1161/CIRCULATIONAHA.123.064257
Volume 147(25) pgs. 1869-1962 June 20, 2023
Sattar, Naveed MD; McMurray, John MD; Boren, Jan MD, PhD; Rawshani, Araz MD, PhD; Omerovic, Elmir MD, PhD; Berg, Niklas MD, PhD; Halminen, Janita MD; Skoglund, Kristoffer MD, PhD; Eliasson, Bjorn MD, PhD; Gerstein, Hertzel C. MD, MSc; McGuire, Darren K. MD, MHSc; Bhatt, Deepak MD, MPH; Rawshani, Aidin MD, PhD
doi : 10.1161/CIRCULATIONAHA.122.063374
The goal of this work was to investigate trends (2001-2019) for cardiovascular events and cardiometabolic risk factor levels in individuals with type 2 diabetes (T2D) and matched control subjects.
Ozkan, Bige MD, ScM; Ndumele, Chiadi E. MD, PhD
Piazza, Gregory MD ,*; Spyropoulos, Alex C. MD ,,,*; Hsia, Judith MD; Goldin, Mark MD; Towner, William J. MD; Go, Alan S. MD; Bull, Todd M. MD; Weng, Stephen PhD; Lipardi, Concetta MD, PhD; Barnathan, Elliot S. MD; Bonaca, Marc P. MD; on behalf of the PREVENT-HD Investigators
doi : 10.1161/CIRCULATIONAHA.123.063901
COVID-19 (coronavirus disease 2019) is associated with heightened risks of venous and arterial thrombosis and hospitalization due to respiratory failure.
Hitsumoto, Tatsuro MD; Tsukamoto, Osamu MD, PhD; Matsuoka, Ken MD, PhD; Li, Junjun PhD; Liu, Li PhD; Kuramoto, Yuki MD, PhD; Higo, Shuichiro MD, PhD; Ogawa, Shou MD; Fujino, Noboru MD, PhD; Yoshida, Shohei MD, PhD; Kioka, Hidetaka MD, PhD; Kato, Hisakazu PhD; Hakui, Hideyuki MD, PhD; Saito, Yuki PhD; Okamoto, Chisato MD; Inoue, Hijiri MS; Hyejin, Jo MS; Ueda, Kyoko MS; Segawa, Takatsugu MD; Nishimura, Shunsuke MD; Asano, Yoshihiro MD, PhD; Asanuma, Hiroshi MD, PhD; Tani, Akiyoshi PhD; Imamura, Riyo PhD; Komagawa, Shinsuke PhD; Kanai, Toshio PhD; Takamura, Masayuki MD, PhD; Sakata, Yasushi MD, PhD; Kitakaze, Masafumi MD, PhD; Haruta, Jun-ichi PhD; Takashima, Seiji MD, PhD
doi : 10.1161/CIRCULATIONAHA.122.062885
Cardiac-specific myosin light chain kinase (cMLCK), encoded by MYLK3, regulates cardiac contractility through phosphorylation of ventricular myosin regulatory light chain. However, the pathophysiological and therapeutic implications of cMLCK in human heart failure remain unclear.
Jani, Vivek MS; Aslam, M. Imran MD; Fenwick, Axel J. PhD; Ma, Weikang PhD; Gong, Henry PhD; Milburn, Gregory BS; Nissen, Devin BS; Cubero Salazar, Ilton M. MD; Hanselman, Olivia; Mukherjee, Monica MD; Halushka, Marc K. MD, PhD; Margulies, Kenneth B. MD; Campbell, Kenneth S. PhD; Irving, Thomas C. PhD; Kass, David A. MD; Hsu, Steven MD
doi : 10.1161/CIRCULATIONAHA.123.064717
Right ventricular (RV) contractile dysfunction commonly occurs and worsens outcomes in patients with heart failure with reduced ejection fraction and pulmonary hypertension (HFrEF-PH).
Capodanno, Davide MD, PhD; Mehran, Roxana MD; Krucoff, Mitchell W. MD; Baber, Usman MD; Bhatt, Deepak L. MD, MPH; Capranzano, Piera MD, PhD; Collet, Jean-Philippe MD, PhD; Cuisset, Thomas MD, PhD; De Luca, Giuseppe MD, PhD; De Luca, Leonardo MD, PhD; Farb, Andrew MD; Franchi, Francesco MD; Gibson, C. Michael MD; Hahn, Joo-Yong MD, PhD; Hong, Myeong-Ki MD, PhD; James, Stefan MD, PhD; Kastrati, Adnan MD; Kimura, Takeshi MD; Lemos, Pedro A. MD; Lopes, Renato D. MD, MHS, PhD; Magee, Adrian MD; Matsumura, Ryosuke MD; Mochizuki, Shuichi MD; O'Donoghue, Michelle L. MD; Pereira, Naveen L. MD; Rao, Sunil V. MD; Rollini, Fabiana MD; Shirai, Yuko MD; Sibbing, Dirk MD; Smits, Peter C. MD, PhD; Steg, P. Gabriel MD; Storey, Robert F. MD; ten Berg, Jurrien MD, PhD; Valgimigli, Marco MD, PhD; Vranckx, Pascal MD; Watanabe, Hirotoshi MD; Windecker, Stephan MD; Serruys, Patrick W. MD, PhD; Yeh, Robert W. MD, MBA; Morice, Marie-Claude MD; Angiolillo, Dominick J. MD, PhD
doi : 10.1161/CIRCULATIONAHA.123.064473
AB Antiplatelet therapy is the mainstay of pharmacologic treatment to prevent thrombotic or ischemic events in patients with coronary artery disease treated with percutaneous coronary intervention and those treated medically for an acute coronary syndrome.
Saha, Prakash PhD ,,*; Gutmann, Clemens MD ,,,*; Kingdon, Jack MBBS; Dregan, Alexandru PhD; Bertolaccini, Laura MD; Grover, Steven P. PhD; Patel, Ashish S. PhD; Modarai, Bijan PhD; Lyons, Oliver PhD; Schulz, Christian MD; Andia, Marcelo E. MD, PhD; Phinikaridou, Alkystis PhD; Botnar, Rene M. PhD; Smith, Alberto PhD
Churchwell, Keith MD; Yeager McSwain, Brooke MSc, MA
Jerome, Gerald J. PhD, FAHA, Chair; Boyer, William R. PhD; Bustamante, Eduardo E. PhD; Kariuki, Jacob PhD, ANP; Lopez-Jimenez, Francisco MD, MSc, FAHA; Paluch, Amanda E. PhD; Swift, Damon L. PhD, FAHA; Webber-Ritchey, Kashica J. PhD, MHA, RN; Barone Gibbs, Bethany PhD, FAHA, Vice Chair; on behalf of the American Heart Association Physical Activity Committee of the Council on Lifestyle and Cardiometabolic Health; Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology; and Council on Peripheral Vascular Disease
doi : 10.1161/CIR.0000000000001148
AB Fewer than 1 in 4 adults achieves the recommended amount of physical activity, with lower activity levels reported among some groups. Addressing low levels of physical activity among underresourced groups provides a modifiable target with the potential to improve equity in cardiovascular health.
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