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Another Effort to Get People With Mental Illness Experiencing Homelessness Off the Streets—A Sound Idea?
Michael F. Hogan, PhD1
doi : 10.1001/jamapsychiatry.2023.0038
June 2023, Vol 80, No. 6, Pages 528-651
Involuntary Hospitalization and Coercive Treatment of People With Mental Illness Experiencing Homelessness—Going Backward With Foreseeable Harms
Nick Kerman, PhD1; Sean A. Kidd, PhD1,2; Vicky Stergiopoulos, MD1,2
Emerging Challenges for Psychedelic Therapy
Jacob S. Aday, PhD1; Robin L. Carhart-Harris, PhD1; Joshua D. Woolley, PhD, MD1,2
International Variation in Clozapine Hematologic Monitoring—A Call for Action
Ebenezer Oloyede, MPharm1,2; David Taylor, PhD3,4; James MacCabe, PhD1,5
Evolutionary Inquiries Into the Origin and Nature of Mental Disorders
Martin Brüne, MD, PhD1
Effect of Brief Interpersonal Therapy on Depression During Pregnancy
Benjamin L. Hankin, PhD1; Catherine H. Demers, PhD2,3; Ella-Marie P. Hennessey, MA2; Sarah E. D. Perzow, PhD2; Mary C. Curran, MSW5; Robert J. Gallop, PhD6; M. Camille Hoffman, MD, MSc3,4; Elysia Poggi Davis, PhD2,7
doi : 10.1001/jamapsychiatry.2023.0702
Importance Prenatal depression is prevalent with negative consequences for both the mother and developing fetus. Brief, effective, and safe interventions to reduce depression during pregnancy are needed.
Effort-Cost Decision-making Among Individuals With Schizophrenia
Elodie Blouzard, MSc1; Arnaud Pouchon, MD1,2; Mircea Polosan, PhD1,2; Julien Bastin, PhD1; Clément Dondé, PhD1,2,3
doi : 10.1001/jamapsychiatry.2023.0553
Importance Motivational impairments in schizophrenia are by definition associated with poor outcome. It is postulated that the reduction of goal-directed behavior arises from abnormal trade-offs between rewards and efforts.
Associations Between Early Life Adversity, Reproduction-Oriented Life Strategy, and Borderline Personality Disorder
Axel Baptista, MD, PhD1,2,3,4; Valérian Chambon, PhD1; Nicolas Hoertel, MD, PhD2,5,6; Mark Olfson, MD, PhD7; Carlos Blanco, MD, PhD8; David Cohen, MD, PhD3,9; Pierre O. Jacquet, PhD4,10,11
doi : 10.1001/jamapsychiatry.2023.0694
Importance Borderline personality disorder (BPD) is often accompanied by a history of high-risk sexual behavior and somatic comorbidities. Yet, these features are most often considered in isolation and little is known about their underlying developmental pathways. Life history theory, a leading framework in evolutionary developmental biology, can help make sense of the wide range of behaviors and health issues found in BPD.
Evaluation of Brain-Body Health in Individuals With Common Neuropsychiatric Disorders
Ye Ella Tian, MBBS, PhD1; Maria A. Di Biase, PhD1; Philip E. Mosley, MD, PhD2,3,4; Michelle K. Lupton, PhD5; Ying Xia, PhD4; Jurgen Fripp, PhD4; Michael Breakspear, MD, PhD6,7; Vanessa Cropley, PhD1; Andrew Zalesky, PhD1,8
doi : 10.1001/jamapsychiatry.2023.0791
Importance Physical health and chronic medical comorbidities are underestimated, inadequately treated, and often overlooked in psychiatry. A multiorgan, systemwide characterization of brain and body health in neuropsychiatric disorders may enable systematic evaluation of brain-body health status in patients and potentially identify new therapeutic targets.
Longitudinal Trends in Suicidal Thoughts and Behaviors Among US Military Veterans During the COVID-19 Pandemic
Ian C. Fischer, PhD1,2; Brandon Nichter, PhD2; Peter J. Na, MD, MPH2,3; Sonya B. Norman, PhD4,5,6; John H. Krystal, MD1,2; Robert H. Pietrzak, PhD, MPH1,2,7
doi : 10.1001/jamapsychiatry.2023.0393
Importance Concerns have been raised since the onset of the COVID-19 pandemic that vulnerable populations, such as military veterans, may be at increased risk of suicidal thoughts and behaviors (STBs).
Associations of Changes in Sleep and Emotional and Behavioral Problems From Late Childhood to Early Adolescence
Rebecca Cooper, MPO1; Maria A. Di Biase, PhD2,3,4; Bei Bei, PhD5; Jon Quach, PhD6,7; Vanessa Cropley, PhD1
doi : 10.1001/jamapsychiatry.2023.0379
Importance Sleep problems and psychopathology symptoms are highly comorbid and bidirectionally correlated across childhood and adolescence. Whether these associations are specific to discrete profiles of sleep problems and specific internalizing and externalizing phenomena is currently unclear.
Interplay of Metabolome and Gut Microbiome in Individuals With Major Depressive Disorder vs Control Individuals
Najaf Amin, PhD1; Jun Liu, PhD1; Bruno Bonnechere, PhD1,2,3; Siamak MahmoudianDehkordi, PhD4; Matthias Arnold, PhD4,5; Richa Batra, PhD6; Yu-Jie Chiou, MSc1,7; Marco Fernandes, PhD8; M. Arfan Ikram, PhD9; Robert Kraaij, PhD10; Jan Krumsiek, PhD6; Danielle Newby, PhD8; Kwangsik Nho, PhD11; Djawad Radjabzadeh, MSc10; Andrew J. Saykin, PhD11; Liu Shi, PhD8; William Sproviero, PhD8; Laura Winchester, PhD8; Yang Yang, PhD1,12; Alejo J. Nevado-Holgado, PhD8; Gabi Kastenmüller, PhD5; Rima Kaddurah-Daouk, PhD4; Cornelia M. van Duijn, PhD1
doi : 10.1001/jamapsychiatry.2023.0685
Importance Metabolomics reflect the net effect of genetic and environmental influences and thus provide a comprehensive approach to evaluating the pathogenesis of complex diseases, such as depression.
Cognitive Function in People With Familial Risk of Depression
Breda Cullen, PhD1; Marc J. Gameroff, PhD2,3; Joey Ward, PhD1; Mark E. S. Bailey, PhD4; Donald M. Lyall, PhD1; Laura M. Lyall, PhD1; Niamh MacSweeney, BA5,6; Eleanor Murphy, PhD2,3; Natasha Sangha, MSc1; Xueyi Shen, PhD5; Rona J. Strawbridge, PhD1,7; Milenna T. van Dijk, PhD2,3; Xingxing Zhu, MSc1; Daniel J. Smith, MD5,6; Ardesheer Talati, PhD2,3; Heather C. Whalley, PhD5,6; Jonathan Cavanagh, MD8; Myrna M. Weissman, PhD2,3,9
doi : 10.1001/jamapsychiatry.2023.0716
Importance Cognitive impairment in depression is poorly understood. Family history of depression is a potentially useful risk marker for cognitive impairment, facilitating early identification and targeted intervention in those at highest risk, even if they do not themselves have depression. Several research cohorts have emerged recently that enable findings to be compared according to varying depths of family history phenotyping, in some cases also with genetic data, across the life span.
Course of Subtypes of Late-Life Depression Identified by Bipartite Network Analysis During Psychosocial Interventions
Nili Solomonov, PhD1; Jihui Lee, PhD2; Samprit Banerjee, PhD, MStat3; Serena Z. Chen, BA1; Jo Anne Sirey, PhD1; Faith M. Gunning, PhD1; Connor Liston, MD, PhD4; Patrick J. Raue, PhD5; Patricia A. Areán, PhD5; George S. Alexopoulos, MD1
doi : 10.1001/jamapsychiatry.2023.0815
Importance Approximately half of older adults with depression remain symptomatic at treatment end. Identifying discrete clinical profiles associated with treatment outcomes may guide development of personalized psychosocial interventions.
Association of the Mediterranean Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet With the Risk of Dementia
Hui Chen, BS1; Klodian Dhana, PhD2,3; Yuhui Huang, BS1; Liyan Huang, BS1; Yang Tao, MS1; Xiaoran Liu, PhD2,3; Debora Melo van Lent, PhD4,5,6; Yan Zheng, MD, PhD7; Alberto Ascherio, MD, DrPH8; Walter Willett, MD, DrPH8; Changzheng Yuan, ScD1,8
doi : 10.1001/jamapsychiatry.2023.0800
Importance Dementia threatens the well-being of older adults, making efforts toward prevention of great importance.
Addressing Equity, Diversity, and Inclusion in the Conduct and Reporting of Genetics Research
Kara S. Bagot, MD1,2; Dost Öngür, MD, PhD3,4
Ketamine vs Electroconvulsive Therapy for Major Depressive Episode
Vikas Menon, MD1; Natarajan Varadharajan, MD2; Abdul Faheem, MD1; Chittaranjan Andrade, MD3
doi : 10.1001/jamapsychiatry.2023.0562
Importance The relative efficacy of ketamine and electroconvulsive therapy (ECT) in adults with major depressive episode (MDE) needs clarification.
Understanding the Mechanisms of Action of Electroconvulsive Therapy
Marta Cano, PhD1,2; Joan A. Camprodon, MD, PhD2
Living Alone and Drug Overdose Deaths in the US
Mark Olfson, MD, MPH1; Candace M. Cosgrove, MPH2; Melanie M. Wall, PhD1; Carlos Blanco, MD, PhD3
Acknowledging Lack of Inclusion in Genetic Analyses
Vani Pariyadath, PhD1
Acknowledging Lack of Inclusion in Genetic Analyses—Reply
Michael Eriksen Benros, MD, PhD1; Rosa Lundbye Allesøe, MSc1; Simon Rasmussen, PhD2
COVID-19 and Mental Health in Young People—Causality or Co-occurrence?
Troels Boldt Rømer, MD1; Rune Haubo Christensen, PhD1; Michael Eriksen Benros, MD, PhD1
COVID-19 and Mental Health in Young People—Causality or Co-occurrence?—Reply
Mette Bliddal, PhD1; Rikke Wesselhoeft, PhD2; Anton Pottegård, PhD2
Errors From Incorrect Use of Subscale
John C. Fortney, PhD1
