New England Journal of Medicine




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سفارش

Ensuring a Reliable Platelet Supply in the United States

William Riley, Ph.D., Claudia S. Cohn, M.D., Ph.D., Kailey Love, M.B.A., M.S., and Jeffrey McCullough, M.D.

doi : 10.1056/NEJMp2302523

Vol. 388 No. 22

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Supporting Robust Teamwork — Bridging Technology and Organizational Science

Anna T. Mayo, Ph.D., Christopher G. Myers, Ph.D., John C. Bucuvalas, M.D., Sandy Feng, M.D., Ph.D., and Courtney E. Juliano, M.D.

doi : 10.1056/NEJMp2300172

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An Invitation to Lunch

Eleanor R. Menzin, M.D.

doi : 10.1056/NEJMp2303125

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Tirofiban for Stroke without Large or Medium-Sized Vessel Occlusion

Wenjie Zi, M.D., Jiaxing Song, M.D., Weilin Kong, M.D., Jiacheng Huang, M.D., Changwei Guo, M.D., Wencheng He, M.D., Yinquan Yu, M.D., Bo Zhang, M.D., Wanjie Geng, M.D., Xiaolin Tan, M.D., Yaoyu Tian, M.D., Zongtao Liu, M.D.,

doi : 10.1056/NEJMoa2214299

The effects of the glycoprotein IIb/IIIa receptor inhibitor tirofiban in patients with acute ischemic stroke but who have no evidence of complete occlusion of large or medium-sized vessels have not been extensively studied.

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Five-Year Follow-up after Transcatheter Repair of Secondary Mitral Regurgitation

Gregg W. Stone, M.D., William T. Abraham, M.D., JoAnn Lindenfeld, M.D., Saibal Kar, M.D., Paul A. Grayburn, M.D., D. Scott Lim, M.D., Jacob M. Mishell, M.D., Brian Whisenant, M.D., Michael Rinaldi, M.D., Samir R. Kapadia, M.D., Vivek Rajagopal, M.D., Ian J. Sarembock, M.B., Ch.B., M.D.,

doi : 10.1056/NEJMoa2300213

Data from a 5-year follow-up of outcomes after transcatheter edge-to-edge repair of severe mitral regurgitation, as compared with outcomes after maximal doses of guideline-directed medical therapy alone, in patients with heart failure are now available.

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Ultrasonography or Radiography for Suspected Pediatric Distal Forearm Fractures

Peter J. Snelling, M.B., B.S., M.P.H.&T.M., Philip Jones, M.Biostat., David Bade, M.B., B.S., Randy Bindra, M.B., B.S., Joshua Byrnes, Ph.D., Michelle Davison, M.B., B.S., Shane George, M.P.H., Mark Moore, M.Nurs.N.P., Gerben Keijzers, Ph.D., and Robert S. Ware, Ph.D. for the BUCKLED Trial Group*

doi : 10.1056/NEJMoa2213883

Data on whether ultrasonography for the initial diagnostic imaging of forearm fractures in children and adolescents is noninferior to radiography for subsequent physical function of the arm are limited.

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Capivasertib in Hormone Receptor–Positive Advanced Breast Cancer

Nicholas C. Turner, M.D., Ph.D., Mafalda Oliveira, M.D., Ph.D., Sacha J. Howell, M.D., Ph.D., Florence Dalenc, M.D., Ph.D., Javier Cortes, M.D., Ph.D., Henry L. Gomez Moreno, M.D., Ph.D., Xichun Hu, M.D., Komal Jhaveri, M.D., Petr Krivorotko, M.D., Ph.D., Sibylle Loibl, M.D., Ph.D., Serafin Morales Murillo, M.D., Meena Okera, M.D., Yeon Hee Park, M.D., Ph.D., Joohyuk Sohn, M.D., Masakazu Toi, M.D., Ph.D., Eriko Tokunaga, M.D., Ph.D., Samih Yousef, M.D., Lyudmila Zhukova, M.D., Ph.D., Elza C. de Bruin, Ph.D., Lynda Grinsted, M.Sc., Gaia Schiavon, M.D., Ph.D., Andrew Foxley, M.F.P.M., and Hope S. Rugo, M.D. for the CAPItello-291 Study Group*

doi : 10.1056/NEJMoa2214131

AKT pathway activation is implicated in endocrine-therapy resistance. Data on the efficacy and safety of the AKT inhibitor capivasertib, as an addition to fulvestrant therapy, in patients with hormone receptor–positive advanced breast cancer are limited.

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Adipocyte Regulation of Insulin Sensitivity and the Risk of Type 2 Diabetes

Anna Santoro, Pharm.D., Ph.D., and Barbara B. Kahn, M.D.

doi : 10.1056/NEJMra2216691

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Phantom Tumor of the Lung

Enrique M. Baldessari, M.D., and Sara M. Mesquida, M.D.

doi : 10.1056/NEJMicm2214264

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Falling-Leaf Motility of Giardia lamblia

Debasish Biswal, M.D., and Bijay Mirdha, M.D.

doi : 10.1056/NEJMicm2211056

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A Wrong Turn

Michael S. Bohnen, M.D., Ph.D., Brahmajee K. Nallamothu, M.D., M.P.H., Robert Zilinyi, M.D., Sanjay Saint, M.D., M.P.H., and Emily D. Slater, M.D.

doi : 10.1056/NEJMcps2215388

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Expanding Treatment for Acute Ischemic Stroke beyond Revascularization

Jose G. Romano, M.D., and Tatjana Rundek, M.D., Ph.D.

doi : 10.1056/NEJMe2303184

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Transcatheter Repair of Secondary Mitral Regurgitation

John J.V. McMurray, M.D., and Marco Metra, M.D.

doi : 10.1056/NEJMe2302924

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Pediatric Dosing Errors during a National Shortage of Fever and Pain Medications

doi : 10.1056/NEJMc2300561

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Mpox among Linked Heterosexual Casual Partners in Bayelsa, Nigeria

doi : 10.1056/NEJMc2300866

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Meningococcal Group B Vaccine (4CMenB) in Children

doi : 10.1056/NEJMc2303518

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