دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
-
http://medilib.ir
- ﻣﺪﺕ ﺯﻣﺎﻥ : 365 ﺭﻭﺯ
قیمت : 3,800,000 تومان- قیمت ویژه : 1,900,000تومان
Gut metabolite mediates neoantigen generation in AS
Jessica McHughÂÂ
doi : 10.1038/s41584-023-00975-9
Volume 19 Issue 6, June 2023
Antibodies cross-reactive with DNase1L3 and dsDNA discovered
Sarah OnuoraÂ
Targeting KDM2/7 histone demethylases could protect against OA
Sarah OnuoraÂÂ
Chimeric receptors broaden the therapeutic landscape for autoimmune disease
Terri H. Finkel & Marko RadicÂ
How does citrullination contribute to RA autoantibody development?
Jean Roudier & Isabelle AugerÂ
Precision medicine in systemic lupus erythematosus
Serena Fasano, Alessandra Milone, Giovanni Francesco Nicoletti, David A. Isenberg & Francesco CicciaÂ
doi : 10.1038/s41584-023-00948-y
Systemic lupus erythematosus (SLE) is an autoimmune disease that has diverse clinical manifestations, ranging from restricted cutaneous involvement to life-threatening systemic organ involvement. The heterogeneity of pathomechanisms that lead to SLE contributes to between-patient variation in clinical phenotype and treatment response.
Juvenile idiopathic inflammatory myositis: an update on pathophysiology and clinical care
Charalampia Papadopoulou, Christine Chew, Meredyth G. Ll. Wilkinson, Liza McCann & Lucy R. WedderburnÂ
doi : 10.1038/s41584-023-00967-9
The childhood-onset or juvenile idiopathic inflammatory myopathies (JIIMs) are a heterogenous group of rare and serious autoimmune diseases of children and young people that predominantly affect the muscles and skin but can also involve other organs, including the lungs, gut, joints, heart and central nervous system.
Matrix metalloproteinases in arthritis: towards precision medicine
Bernard Grillet, Rafaela Vaz Sousa Pereira, Jo Van Damme, Ahmed Abu El-Asrar, Paul Proost & Ghislain OpdenakkerÂ
doi : 10.1038/s41584-023-00966-w
Proteolysis of structural molecules of the extracellular matrix (ECM) is an irreversible post-translational modification in all arthropathies. Common joint disorders, including osteoarthritis and rheumatoid arthritis, have been associated with increased levels of matrix remodelling enzymes, including matrix metalloproteinases (MMPs).
Evidence-Based Guideline for the diagnosis and management of eosinophilic granulomatosis with polyangiitis
Giacomo Emmi, Alessandra Bettiol, Elena Gelain, Ingeborg M. Bajema, Alvise Berti, Stella Burns, Maria C. Cid, Jan W. Cohen Tervaert, Vincent Cottin, Eugenia Durante, Julia U. Holle, Alfred D. Mahr, Marcos Martinez Del Pero, Chiara Marvisi, John Mills, Sergey Moiseev, Frank Moosig, Chetan Mukhtyar, Thomas Neumann, Iacopo Olivotto, Carlo Salvarani, Benjamin Seeliger, Renato A. Sinico, Camille Taillé, Benjamin Terrier, Nils Venhoff, George Bertsias, Loïc Guillevin, David R. W. Jayne & Augusto VaglioÂ
doi : 10.1038/s41584-023-00958-w
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, characterized by asthma, eosinophilia and granulomatous or vasculitic involvement of several organs.
