Probiotics and Antimicrobial Proteins




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سفارش

Lacticaseibacillus casei LH23 Suppressed HPV Gene Expression and Inhibited Cervical Cancer Cells

Shiyue Hu, Yunpeng Hao, Xiao Zhang, Yaping Yang, Meiling Liu, Nan Wang, Tong-Cun Zhang & Hongpeng He

doi : 10.1007/s12602-021-09848-7

Volume 15, issue 3, June 2023

Microbiota of lower female reproductive tract is special in its microorganism composition with Lactobacillus as the predominant bacteria. A few of Lactobacillus species have been identified to benefit the inhibition of inflammatory and malignant diseases.

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Lactobacillus johnsonii BFE6154 Ameliorates Diet-Induced Hypercholesterolemia

Hongsup Yoon, Yuri Lee, Haryung Park, Hye-Ji Kang, Yosep Ji & Wilhelm H. Holzapfel

doi : 10.1007/s12602-021-09859-4

The functional characteristics of Lactobacillus johnsonii BFE6154, first isolated from Maasai traditional fermented milk, were previously identified in vitro, but its cholesterol-lowering properties have not been verified yet.

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Efficacy of a Probiotic Consisting of Lacticaseibacillus rhamnosus PDV 1705, Bifidobacterium bifidum PDV 0903, Bifidobacterium longum subsp. infantis PDV 1911, and Bifidobacterium longum subsp. longum PDV 2301 in the Treatment of Hospitalized Patients with COVID-19: a Randomized Controlled Trial

Vladimir Ivashkin, Victor Fomin, Sergey Moiseev, Michail Brovko, Roman Maslennikov, Anatoly Ulyanin, Victoria Sholomova, Maria Vasilyeva, Elizaveta Trush, Oleg Shifrin & Elena Poluektova

doi : 10.1007/s12602-021-09858-5

The treatment of coronavirus disease (COVID-19) and COVID-19-associated diarrhea remains challenging. This study aimed to evaluate the efficacy of a multi-strain probiotic in the treatment of COVID-19. This was a randomized, controlled, single-center, open-label trial (NCT04854941).

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Effects of Lactic Acid Bacteria Isolated from Equine on Salmonella-Infected Gut Mouse Model

Lulu Pei, Juanjuan Liu, Zonghao Huang, ·Mudassar Iqbal & Yaoqin Shen

doi : 10.1007/s12602-021-09841-0

The aim of this study was to evaluate the antibacterial potential of lactic acid bacteria (Weissella confuse, Pediococcus acidilactici, and Ligilactobacillus equi) isolated from healthy equine in Wuhan against Salmonella Typhimurium CVCC542-induced mice model on intestinal microflora. In previous studies, these isolated strains showed good probiotic potentials in vitro.

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Evaluation of Potential Probiotic Properties of Lactobacillus and Bacillus Strains Derived from Various Sources for Their Potential Use in Swine Feeding

Nuntiya Pahumunto, Gunnar Dahlen & Rawee Teanpaisan

doi : 10.1007/s12602-021-09861-w

Beneficial effects of probiotics are relevant to the various potential properties of individual strains, and they may also relate to the original sources of the probiotic strains. This study aimed to characterize the potential probiotic properties of the strains originating from various sources for probiotics use in swine feeding.

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Isolation and Identification of Potential Probiotic Bacteria from Human Milk

Quésia S. Damaceno, Bruno Gallotti, Isabela M. M. Reis, Yasmim C. P. Totte, Gabriella B. Assis, Henrique C. Figueiredo, Tales F. Silva, Vasco Azevedo, Jacques R. Nicoli & Flaviano S. Martins

doi : 10.1007/s12602-021-09866-5

Breast milk was long considered a sterile environment, but now it is known to harbor many bacteria that will shape the newborn microbiota. The benefits of breastfeeding to newborn health are, on some level, related to the presence of beneficial bacteria in human milk.

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Inhibition of Serine Protease, α-Amylase and Growth of Phytopathogenic Fungi by Antimicrobial Peptides from Capsicum chinense Fruits

Larissa Maximiano Resende, Érica de Oliveira Mello, Mariana Carvalho de Lima Aguieiras, Celso Shiniti Nagano, Renata Pinheiro Chaves, Gabriel Bonan Taveira, Marciele Souza da Silva, André de Oliveira Carvalho, Rosana Rodrigues & Valdirene Moreira Gomes

doi : 10.1007/s12602-021-09865-6

Plant fungal diseases cause major problems for the global economy. Antimicrobial peptides have aroused great interest in the control of phytopathogens, as they are natural molecules and have a broad spectrum of inhibitory activity.

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Phenazine 1-carboxylic acid Producing Seed Harbored Endophytic Bacteria from Cultivated Rice Variety of Kerala and Its Broad Range Antagonism to Diverse Plant Pathogens

Nayana Aluparambil Radhakrishnan, Aswani Ravi, Bicky Jerin Joseph, Ashitha Jose, O. Jithesh & Radhakrishnan Edayileveettil Krishnankutty

doi : 10.1007/s12602-021-09844-x

Endophytic microorganisms residing within the diverse parts of plants play a significant role in the plant growth and defense response. In the case of the vertically transmitted seed-borne endophytes, they form the promising initiator of the juvenile plant microbiome by supporting the growth and establishment of the seedlings.

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Alterations in Faecal Microbiota and Elevated Levels of Intestinal IgA Following Oral Administration of Lacticaseibacillus casei in mice

Georgios Aindelis, Petros Ypsilantis & Katerina Chlichlia

doi : 10.1007/s12602-021-09864-7

The intestinal microbiota has been identified as a crucial regulator of the overall health, with studies describing its influence in a variety of disorders and developmental processes throughout the body. A widely accepted approach of influencing the microbiota and regulating its functionality in health or disease is the consumption of probiotics.

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Promotion of Egg Production Rate and Quality Using Limosilactobacillus oris BSLO 1801, a Potential Probiotic Screened from Feces of Laying Hens with Higher Egg Productive Performance

Zhiqiang Wan, Ning Sun, Min Luo, Baoxing Gan, Zhipeng Yao, Xi Cao, Hesong Wang, Kangcheng Pan, Gang Shu, Yan Zeng, Dong Zeng & Xueqin Ni

doi : 10.1007/s12602-021-09856-7

In this experiment, laying hens were divided into a high productive group (group H) and a low productive group (group L). The purpose of this experiment was to screen and isolate a potential probiotic associated with the laying rate from group H by comparing the results via 16S rDNA high-throughput sequencing.

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Distribution of Genes Related to Probiotic Effects Across Lacticaseibacillus rhamnosus Revealed by Population Structure

Lorena Dutra-Silva, Filipe P. Matteoli & Ana Carolina Maisonnave Arisi

doi : 10.1007/s12602-021-09868-3

The Gram-positive Lacticaseibacillus rhamnosus has been broadly reported as capable of exerting beneficial health effects. Bacterial genomic diversity may promote niche specialization, thus creating subpatterns within populations.

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Compound Probiotics Improve Body Growth Performance by Enhancing Intestinal Development of Broilers with Subclinical Necrotic Enteritis

Ning Sun, Yan Xue, Siyi Wei, Bangyuan Wu, Hesong Wang, Dong Zeng, Ying Zhao, Abdul Khalique, Kangcheng Pan, Yan Zeng, Gang Shu, Bo Jing & Xueqin Ni

doi : 10.1007/s12602-021-09867-4

The aim of this study is to explore whether or not the combined application of BS15 and H2 is capable to have a more effective control effect on SNE in broilers.

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Application of Potentially Probiotic Fruit-Derived Lactic Acid Bacteria Loaded into Sodium Alginate Coatings to Control Anthracnose Development in Guava and Mango During Storage

Karina Felix Dias Fernandes, Kataryne �rabe Rimá de Oliveira & Evandro Leite de Souza

doi : 10.1007/s12602-021-09871-8

This study evaluated the efficacy of potentially probiotic fruit-derived lactic acid bacteria (LAB) strains loaded into sodium alginate (SA) coatings to control the anthracnose development in guava cv. Paluma and mango cv.

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Probiotic Potential, Safety Properties, and Antifungal Activities of Corynebacterium amycolatum ICIS 9 and Corynebacterium amycolatum ICIS 53 Strains

I. V. Gladysheva, K. L. Chertkov, S. V. Cherkasov, Y. A. Khlopko, V. Y. Kataev & A. V. Valyshev

doi : 10.1007/s12602-021-09876-3

The purpose of this study was to evaluate the probiotic characteristics and safety and to study the antifungal activity of C. amycolatum ICIS 9 and C. amycolatum ICIS 53 against Candida spp.

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Limosilactobacillus fermentum Strains with Claimed Probiotic Properties Exert Anti-oxidant and Anti-inflammatory Properties and Prevent Cardiometabolic Disorder in Female Rats Fed a High-Fat Diet

Micaelle Oliveira de Luna Freire, Luciana Caroline Paulino do Nascimento, Kataryne �rabe Rimá de Oliveira, Alisson Macário de Oliveira, Marcos dos Santos Lima, Thiago Henrique Napoleão, João Henrique da Costa Silva, Cláudia Jacques Lagranha, Evandro Leite de Souza & José Luiz de Brito Alves

doi : 10.1007/s12602-021-09878-1

This study assessed the effects of a mixed formulation containing Limosilactobacillus (L.) fermentum 139, L. fermentum 263, and L. fermentum 296 on cardiometabolic parameters, inflammatory markers, short-chain fatty acid (SCFA) fecal contents, and oxidative stress in colon, liver, heart, and kidney tissues of female rats fed a high-fat diet (HFD).

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Probiotic Characterization of Indigenous Kocuria flava Y4 Strain Isolated from Dioscorea villosa Leaves

doi : 10.1007/s12602-021-09877-2

This aim of the study was to isolate and screen potential probiotics from Dioscorea villosa leaves. The potential isolate Y4 was obtained from the Dioscorea villosa leaves, and its ability to grow in a medium containing high NaCl concentrations (2–10%) indicated its negative hemolytic activity.

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Genomic Analyses of Pediococcus pentosaceus ST65ACC, a Bacteriocinogenic Strain Isolated from Artisanal Raw-Milk Cheese

Pediococcus pentosaceus ST65ACC was obtained from a Brazilian artisanal cheese (BAC) and characterized as bacteriocinogenic. This strain presented beneficial properties in previous studies, indicating its potential as a probiotic candidate.

doi : 10.1007/s12602-021-09894-1

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Cloning, Characterization, and Antibacterial Properties of Endolysin LysE Against Planktonic Cells and Biofilms of Aeromonas hydrophila

Pallavi Baliga, Puneeth Thadooru Goolappa, Malathi Shekar & Girisha Shivani Kallappa

doi : 10.1007/s12602-021-09880-7

Multidrug-resistant bacteria are emerging as a major global threat to public health. Bacteriophages are an important source of antimicrobial enzymes and could be developed as an alternative antibiotic candidate.

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The Combined Effects of Propionic Acid and a Mixture of Bacillus spp. Probiotic in a Plant Protein–Rich Diet on Growth, Digestive Enzyme Activities, Antioxidant Capacity, and Immune-Related Genes mRNA Transcript Abundance in Lates calcarifer Fry

Mostafa Salehi, Dara Bagheri, Ebrahim Sotoudeh, Ahmad Ghasemi & Mansour Torfi Mozanzadeh

doi : 10.1007/s12602-021-09902-4

A 7-week feeding trial was conducted to evaluate the combined effects of propionic acid (PA, 5 or 10 g/kg) and a multi-strain Bacillus spp. (Bacillus subtilis IS02 (accession no. JN856456) and B. licheniformis IBRC-M 11,319) (1.7 × 107 CFU/g) probiotic in a plant protein source (PP)–rich diet (∼70% of dietary protein derived from PP sources) on performance of Asian sea bass (Lates calcarifer) fry (initial body weight 2.97 ± 0.11 g). In this regard, six isoproteic (∼48%) diets were formulated as follows: a control (without supplementation of the additives); probiotic (only contained Bacillus spp. mixture); 5 g PA/kg diet; 10 g PA/kg diet; probiotic + 5 g PA/kg diet, and probiotic + 10 g PA/kg diet.

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Multi-functional Potential of Five Lactic Acid Bacteria Strains Derived from Giant Panda (Ailuropoda melanoleuca)

Jie Wang, Yang Pu, Yan Zeng, Yingyi Chen, Wei Zhao, Lili Niu, Benhao Chen, Zihan Yang, Liqian Wu, Kangcheng Pan, Bo Jing, Dong Zeng & Xueqin Ni

doi : 10.1007/s12602-021-09881-6

The multi-functional properties of lactic acid bacteria (LAB) on host health have been a popular research topic. The aim of present study was to assess the multi-functional potential of five LAB strains isolated from giant panda.

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Optimization of Growth Conditions for the Production of Bacillus subtilis Using Central Composite Design and Its Antagonism Against Pathogenic Fungi

Meyrem Vehapi, Benan İnan, Selma Kayacan-Cakmakoglu, Osman Sagdic & Didem Özçimen

doi : 10.1007/s12602-021-09904-2

Today, the enhancement of spore yields of Bacillus subtilis has considerable interest and has been widely investigated. In this context, studies have been carried out to improve the spore yield as well as the production amount.

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Effects of Antimicrobial Peptides Gal-13 on the Growth Performance, Intestinal Microbiota, Digestive Enzyme Activities, Intestinal Morphology, Antioxidative Activities, and Immunity of Broilers

Yufei Wang, Jianzhen Li, Xixi Dai, Zhenhua Wang, Xueqin Ni, Dong Zeng, Yan Zeng, Dongmei Zhang & Kangcheng Pan

doi : 10.1007/s12602-021-09905-1

To evaluate the application effect of antimicrobial peptides Gal-13 (AMP Gal-13) instead of antibiotic feed additives, 90 7-day-old Ross 308 broilers were randomly divided into 3 groups. Group A was fed a basic diet as the control, and Groups B and C were supplemented with AMP Gal-13 (100 mg/kg and 200 mg/kg, respectively).

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Effects of Bacillus subtilis BS-Z15 on Intestinal Microbiota Structure and Body Weight Gain in Mice

Jun Yang, Huan-Chen Ning, Qi Zhang, Jun-Qi Yue, Xi-Yuan Cao, Jin-Yu Li, Ling Liu, He-Ping Zhao & Hui-Xin Zhao

doi : 10.1007/s12602-021-09897-y

In our previous study, we identified a metabolite of Bacillus subtilis BS-Z15 (a strain with probiotic characteristics) that could improve immunity in mice. In the present study, we examined the effects of B. subtilis BS-Z15 and its metabolites on body weight gain and the intestinal microbiota of mice.

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Safety Evaluation of Goat Milk Added with the Prebiotic Inulin Fermented with the Potentially Probiotic Native Culture Limosilactobacillus mucosae CNPC007 in Co-culture with Streptococcus thermophilus QGE: Analysis of Acute and Repeated Dose Oral Toxicity

�urea Marcela de Souza Pereira, Larissa Caroline de Almeida Sousa Lima, Laisa Wanessa Santos Lima, Tamires Meira Menezes, Ângela Magalhães Vieira, Eryvelton de Souza Franco, Silvânia Tavares Paz, Carina Scanoni Maia, Antônio Sílvio do Egito, Karina Maria Olbrich dos Santos, Flávia Carolina Alonso Buriti & Maria Bernadete de Sousa Maia

doi : 10.1007/s12602-021-09898-x

Despite functional goat milk products having emerged due to their importance for human nutrition and health, few studies have assessed the safety of consumption of goat dairy products containing potentially probiotic autochthonous lactic acid bacteria supplemented with prebiotic carbohydrates.

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Effects of the Probiotic Lactiplantibacillus plantarum KU15120 Derived from Korean Homemade Diced-Radish Kimchi Against Oxidation and Adipogenesis

Na-Kyoung Lee, Kyoung Jun Han, Hoon Park & Hyun-Dong Paik

doi : 10.1007/s12602-021-09885-2

Intestinal microflora can influence abnormal adipocyte growth. Therefore, this study was aimed to investigate the probiotic properties and antioxidant and antiobesity effects of isolated strains from homemade kimchi

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Bifidobacterium lactis CCT 7858 Improves Gastrointestinal Symptoms by Antibiotics Treatment: a Double-Blind, Randomized, Placebo-Controlled Trial

Monique Michels, Emily Córneo, Luana Cucker, Carla Sasso Simon, Gabriel Fernandes Alves de Jesus, Carolina Michels, Kristian Madeira, Ana Paula Voytena, Marina Rossetto, Fernanda Ramlov, Danusa de Castro Damásio & Felipe Dal-Pizzol

doi : 10.1007/s12602-021-09900-6

Diarrhea is one of the most frequent side effects of antibiotic treatment and occurs in 25 to 40% of patients in use. One potential strategy to prevent this side effect is the concurrent use of probiotics. This study evaluated the efficacy of the strain Bifidobacterium lactis CCT 7858 in the prevention of diarrhea and improvement of gastrointestinal symptoms in hospitalized patients using antibiotics.

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Simultaneous Production of Antibacterial Protein and Lipopeptides in Bacillus tequilensis, Detected by MALDI-TOF and GC Mass Analyses

Fatemeh S. Ghoreishi, Rasoul Roghanian & Giti Emtiazi

doi : 10.1007/s12602-021-09883-4

As antibiotic resistance is nowadays one of the important challenges, efforts are crucial for the discovery of novel antibacterial drugs. This study aimed to evaluate antimicrobial/anticancerous activities of halophilic bacilli from the human microbiota.

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In Vitro Characterisation Revealed Himalayan Dairy Kluyveromyces marxianus PCH397 as Potential Probiotic with Therapeutic Properties

Deepika Nag, Abhishek Goel, Yogendra Padwad & Dharam Singh

doi : 10.1007/s12602-021-09874-5

Recently, probiotics have gained much attention for their roles against various clinical conditions. Obesity is a worldwide health problem that triggers various other major complications like type 2 diabetes (T2D) and cancers, including colorectal cancer (CRC).

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Heat-Killed Levilactobacillus brevis as a Candidate Postbiotics Through Immunostimulation Mediated by Macrophage-Inducible C-Type Lectin

Tomoyuki Shimazu, Mai Suzuki, Ryo Takasaki, Asuka Besshi, Yuna Suzuki & Yoichiro Iwakura

doi : 10.1007/s12602-021-09890-5

To understand the beneficial health-promoting effects of lactic acid bacteria (LAB) on immune cells, it is necessary to understand the relationship between LAB and innate immune receptors. We investigated the possible involvement of C-type lectin receptors (CLRs) in the immune-stimulating function of LAB in several strains.

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Potential Probiotic Properties of Blautia producta Against Lipopolysaccharide-Induced Acute Liver Injury

Bingyong Mao, Weiling Guo, Xuemei Liu, Shumao Cui, Qiuxiang Zhang, Jianxin Zhao, Xin Tang & Hao Zhang

doi : 10.1007/s12602-023-10044-y

Blautia is a genus of anaerobic microbe extensively present in the intestine and feces of mammals. This study aims to investigate the influence of Blautia producta to prevent lipopolysaccharide (LPS)-induced acute liver injury (ALI) and elaborate on its hepatoprotective mechanisms.

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