Acta Paediatrica, International Journal of Paediatrics




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Issue highlights

Anna Käll, Hugo Lagercrantz

doi : 10.1111/apa.16849

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The febrile infant: Is it COVID-19 or a serious bacterial infection?

Andreas Ohlin

doi : 10.1111/apa.16783

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Molecular diagnostics for invasive lung infections in children

Alasdair P. S. Munro

doi : 10.1111/apa.16797

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Evidence, hints and assumptions for late pregnancy in the Ancient Mediterranean and Near East

Ariadne Malamitsi-Puchner, Ioannis M. Konstantakos

doi : 10.1111/apa.16781

Ancient women, who survived childhood mortality, received good and adequate nutrition, did not work hard and escaped death during childbirth could live fairly long lives. Girls started procreation after marriage, usually at 15 years, had on average seven children, childbearing lasted 14–21 or more years and could happen at the age of 35 or more years.

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Systematic review and meta-analysis showed that complementary and alternative medicines were not effective for infantile colic

Sara Cabanillas-Barea, Sandra Jiménez-del-Barrio, Andoni Carrasco-Uribarren, Anna Ortega-Martínez, Silvia Pérez-Guillén, Luis Ceballos-Laita

doi : 10.1111/apa.16807

Osteopathy and chiropractic techniques are used for babies for different reasons, but it is unclear how effective they are. The aim of this study was to evaluate their effectiveness in reducing crying time and increasing sleeping time in babies with infantile colic.

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The San Diego SIDS definition�20 Years on

Roger W. Byard, Luzern Tan

doi : 10.1111/apa.16777

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Why do we fear bottles and pacifiers?

Ilari Kuitunen

doi : 10.1111/apa.16780

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Resuscitation thresholds were seen as guidance by Belgian neonatologists and other relevant factors were included in decision-making

Alice Cavolo, Chris Gastmans

doi : 10.1111/apa.16803

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The evolving relationship between COVID-19 and serious bacterial infection evaluation in febrile neonates

David Guernsey III, Shannon Kostin, Michael Silver, Hector Vazquez, Jessica Zerzan

doi : 10.1111/apa.16655

The COVID-19 omicron variant surge highlighted the evolving impact of COVID-19. Febrile infants <60 days old are high risk for serious bacterial infections (SBI). This study evaluated the rate of SBI based on COVID-19 infection.

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Cardiac output and regional-cerebral-oxygen-saturation in preterm neonates during immediate postnatal transition: An observational study

Daniel Pfurtscheller, Christina H. Wolfsberger, Nina Höller, Bernhard Schwaberger, Lukas P. Mileder, Nariae Baik-Schneditz, Berndt Urlesberger, Georg M. Schmölzer, Gerhard Pichler

doi : 10.1111/apa.16745

To examine potential correlations between cardiac output (CO) with cerebral-regional-oxygen-saturation (crSO2) and cerebral-fractional-tissue-oxygen-extraction (cFTOE) during immediate foetal-to-neonatal transition in term and preterm neonates with and without respiratory support.

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Association of response time and intermittent hypoxemia in extremely preterm infants

Sven Martin, Benjamin W. Ackermann, Ulrich H. Thome, Martin Grunwald, Stephanie M. Müller

doi : 10.1111/apa.16766

To determine the relationship between medical staff's response time (RT) to oxygen saturation (SpO2) below 80% and the associated time from tactile intervention until SpO2 normalisation (CT).

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Preterm birth in the Nordic countries�Capacity, management and outcome in neonatal care

Mikael Norman, Jesper Padkær Petersen, Hans Jørgen Stensvold, Thordur Thorkelsson, Kjell Helenius, Charlotte Brix Andersson, Heidi Ørum Cueto, Magnus Domellöf, Mika Gissler, Anna Heino, Stellan HÃ¥kansson, Baldvin Jonsson, Claus Klingenberg, Liisa Lehtonen, Marjo Metsäranta, Arild E. Rønnestad, Simon Trautner

doi : 10.1111/apa.16753

Organisation of care, perinatal and neonatal management of very preterm infants in the Nordic regions were hypothesised to vary significantly. The aim of this observational study was to test this hypothesis.

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There are already enough studies on sweet solutions for neonatal procedural pain and more would be unethical and unnecessary

Tian Lin, Hao-fei Qiu, Rui-rui Huang, Tao Zhang, Denise Harrison

doi : 10.1111/apa.16784

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Parents and healthcare professionals' attitudes to Kangaroo Care for preterm infants in the United Kingdom

Saskia Walker, Shalini Ojha, Eleanor J. Mitchell

doi : 10.1111/apa.16795

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Weight a minute: The smaller and more immature, the more predictable the autonomic regulation?

Alexander Mildalen Stålhammar, Antoine Honoré, Katja Adolphson, David Forsberg, Eric Herlenius, Kerstin Jost

doi : 10.1111/apa.16796

To investigate the relation between autonomic regulation, measured using heart rate variability (HRV), body weight and degree of prematurity in infants. Further to assess utility to include body weight in a machine learning-based sepsis prediction algorithm.

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The timing and quality of sleep was associated with dietary quality and anthropometry in toddlers born preterm

Samrawit F. Yisahak, Kelly M. Boone, Joseph Rausch, Sarah A. Keim

doi : 10.1111/apa.16750

The aim of the study was to examine prospective associations of sleep characteristics (duration, timing, quality) with dietary and anthropometric measures among toddlers born preterm (<35 weeks).

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Gratitude, fragility and strength: Perspectives of adults born preterm about prematurity

Camille Girard-Bock, Thuy Mai Luu, Claude Julie Bourque, Anne Monique Nuyt, Keith J. Barrington, Annie Janvier

doi : 10.1111/apa.16779

The aim of the study was to explore how young adults thought that being born preterm had affected their lives.

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No impact of parental singing during the neonatal period on cognition in preterm-born children at 2–3 years

Kaisamari Kostilainen, Pernilla Hugoson, Anu Haavisto, Eino Partanen, Kaija Mikkola, Minna Huotilainen, Satu Pakarinen, Catarina Furmark, Ulrika Ã…dén, Vineta Fellman

doi : 10.1111/apa.16788

Studies examining the long-term effects of neonatal music interventions on the cognition of children born preterm are scarce. We investigated whether a parental singing intervention before term age improves cognitive and language skills in preterm-born children.

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Polymorphisms of the hypothalamic–pituitary–adrenal axis may lead to an inadequate response to stress and contribute to sudden infant death syndrome

Elanur Uzuntas, Peter Schürmann, Thomas Rothämel, Thilo Dörk, Michael Klintschar

doi : 10.1111/apa.16772

Impaired resilience to stress may be a factor in sudden infant death syndrome (SIDS). However, no comprehensive studies have been performed on polymorphisms that are relevant to the hypothalamic–pituitary–adrenal (HPA) axis, which regulates the stress hormone cortisol.

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Infants were introduced to complementary feeding earlier in 2018 compared with 2003

Frida Strömberg Celind, Emma Goksör, Elisabeth Carlén, Birte Schilling, Bernt Alm, Göran Wennergren

doi : 10.1111/apa.16763

Until 2001, the Swedish advice was to postpone the introduction of eggs, fish and peanuts until the age of 1 year. One reason was to reduce the risk of food allergy. The earlier introduction of complementary feeding is now advised. Our aim was to study adherence to current recommendations and whether the time of introduction changed between 2003 and 2018.

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Croatian mothers were 11 times more likely to give their newborn infants formula in hospital if they had used it for their older children

Ana Vidović Roguljić, Jakov Matas, Irena Zakarija-Grković

doi : 10.1111/apa.16802

We determined the prevalence and predictors of formula supplementation for healthy, term newborn infants in hospital.

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The role of parental congruence in pre-school children's screen time, moderated by parental education

Alissa J. Burnett, Carola Ray, Reetta Lehto, Marja H. Leppänen, Nina Sajaniemi, Maijaliisa Erkkola, Eva Roos

doi : 10.1111/apa.16782

This study investigated whether parental congruency regarding screen time (ST) is associated with ST in pre-school children. In addition, we investigated whether parental education levels moderated this relationship.

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Effects of prenatal exposure to maternal diabetes mellitus on deep grey matter structures and attention deficit hyperactivity disorder symptoms in children

Samson Nivins, Torkel Klingberg

doi : 10.1111/apa.16756

The neuronal mechanism linking the association between maternal diabetes mellitus (DM) and risk of attention deficit hyperactivity disorder (ADHD) symptoms and working memory deficits in children was investigated.

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Postural balance under sensory manipulation predicted fine and gross motor skills in children from 5 to 6 years of age

Khouloud Mnejja, Jose Luis García-Soidan, Vicente Romo-Perez, Sonia Sahli

doi : 10.1111/apa.16776

Our aim was to identify predictors of fine and gross motor skills at 5–6 years of age using postural balance under sensory manipulation.

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Norwegian paediatric habilitation centres judge their own competence on cerebral visual impairment as limited

Pamela Friede, Sandra Julsen Hollung, Torstein Vik, Guro Lillemoen Andersen, David Lansing Cameron, Sigrid Aune de Rodez, Olav H. Haugen, Tonje Lundervold, Jude Nicholas, Kristine Stadskleiv

doi : 10.1111/apa.16778

Cerebral visual impairment (CVI), a frequently occurring functional impairment in children with neurodevelopmental disorders, leads to communicative, social and academic challenges. In Norway, children with neurodevelopmental disorders are assessed at paediatric habilitation centres. Our aims were to explore how CVI is identified, how paediatric habilitation centres assess their CVI competence and the reported prevalence of CVI among children with cerebral palsy.

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Different aspects of visual perception are important for 12-year social functioning depending on gestational age

Martin Johansson, Ylva Fredriksson Kaul, Cecilia Montgomery, Eva Larsson, Lena Hellström-Westas, Olga Kochukhova

doi : 10.1111/apa.16794

Perceptual mechanisms in social functioning might promote interventions. We investigated relations between visual perception and social functioning, in preterm children.

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Obesity increased the risk of SARS-CoV-2 positivity in children

D. R. Zimmerman, M. Goldberg, M. Blaychfeld Magnazi, S. Alroy Preis, R. Endevelt

doi : 10.1111/apa.16785

A population-based, cross-sectional study combining the Israeli Growth Survey and COVID-19 data for children with at least one SARS-CoV-2 test from 16 February 2020 to 20 December 2021. Overweight and obesity status were based on body mass index and the Center for Disease Control criteria. Multivariate logistics regression was performed to validate reliability for weight categories at the age of approximately 6 years compared with weights at approximately 12 years.

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Parapneumonic effusion in children: Rapid pathogen detection in pleural fluid using multiplex bacterial PCR

Ulrikka Nygaard, Nikolai Søren Kirkby, Joakim Bloch, Naqash Javaid Sethi, Alex Christian Yde Nielsen, Anja Poulsen, Frederik Buchvald, Marie-Louise von Linstow, Nadja Hawwa Vissing

doi : 10.1111/apa.16768

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Food protein-induced enterocolitis syndrome among children in northern Sweden�A retrospective review from 2004–2018

Magnus Öhlund, Sara Liljeholm, Ã…sa Strinnholm, Anna Winberg

doi : 10.1111/apa.16741

To describe clinical presentation and development of tolerance among children with Food protein-induced enterocolitis syndrome (FPIES) in a population in northern Sweden.

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Neurological complications of rotavirus infection in children: A systematic review and meta-analysis

A. Meyer, C. Mazzara, S. A. G. Lava, G. Treglia, M. G. Bianchetti, B. Goeggel Simonetti, G. D. Simonetti

doi : 10.1111/apa.16775

To systematically review the clinical features and outcomes of paediatric patients developing neurological complications associated with a rotavirus infection.

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Development of video tutorials to help parents manage children with acute illnesses using a modified Delphi method

L. Borch-Johnsen, L. Andrés-Jensen, F. Folke, M. M. Espersen, S. L. Amstrup, M. S. Frederiksen, L. K. Gjærde, B. R. Hjelvang, M. J. Kristoffersen, L. Lundby-Christensen, M. Schrøder, K. B. Spangenberg, S. Lund, D. Cortes

doi : 10.1111/apa.16805

Children often fall sick, which causes concern among parents. Online health information can be confusing and difficult to understand. We aimed to produce simple, informative video tutorials on the symptoms ill children present.

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The Ortolani test has a high positive predictive value in clinical hip screening for developmental dysplasia of the hip

M. Maikku, T. Rantala, M. Valkama

doi : 10.1111/apa.16757

Previous studies have not described separate positive predictive values for Ortolani and Barlow tests in clinical hip screening. We aimed to determine the positive predictive values at discharge following birth, in predicting dysplasia or instability in the subsequent hip ultrasound examinations.

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Elevated creatine kinase is mainly harmless in children but persistent and severe hyperCKaemia should raise suspicions of serious muscle damage

Francesca Burlo, Veronica Grigoletto, Serena Pastore, Anna Vaivoda, Andrea Trombetta, Gianluca Tamaro, Andrea Magnolato, Alberto Tommasini, Andrea Taddio

doi : 10.1111/apa.16755

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Urine collection techniques in non-toilet trained children: Switzerland's paediatric office practices in 2022

Chloé Progin, Jean-Yves Pauchard, Michael Amiguet, Bernard Laubscher

doi : 10.1111/apa.16758

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Complication rate after gastrostomy placement in children can be reduced by simple surgical steps

Therese Hössjer, Gunnar Göthberg, Einar Arnbjörnsson, Jan Rutqvist, Frans Perris, Zsuzsa Bartik, Markus Almström, Torbjörn Backman, Johan Danielson

doi : 10.1111/apa.16792

To evaluate if the incidence of postoperative complications after gastrostomy placement is correlated to perioperative parameters or patient characteristics.

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EBNEO commentary: Early amino acids in extremely preterm infants and neurodisability at 2 years

Jane Stremming, Laura D. Brown

doi : 10.1111/apa.16774

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EBNEO commentary: Weaning from CPAP using high-flow is non-inferior to using CPAP alone in very preterm infants

Nonye Ijeoma Ezeh, Teim Jengoa Eyo, Kalyana Gurusamy

doi : 10.1111/apa.16799

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