دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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http://medilib.ir
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Basic clinical management of preschool wheeze
Andrew Bush
doi : 10.1111/pai.13988
Preschool wheeze is very common and often difficult to treat. Most children do not require any investigations; only a detailed history and physical examination to ensure an alternative diagnosis is not being missed; and the differential diagnosis, and hence investigation protocols for the child in whom a major illness is suspected, shows geographical variation.
Dietary prevention strategies for childhood asthma
Nicklas Brustad, Klaus Bønnelykke, Bo Chawes
doi : 10.1111/pai.13984
Asthma is the most common chronic disease in childhood and a rise in prevalence has been observed concomitantly with changing dietary habits in the Western world. This change has favored a more Westernized diet characterized by high intake of processed food and fat in contrast to a Mediterranean diet high in fruit, vegetable and fish intake.
Siblings and risk of allergic rhinitis: A systematic review and meta-analysis
Daniil Lisik, Saliha Selin Özuygur Ermis, Athina Ioannidou, Gregorio Paolo Milani, Sungkutu Nyassi, Giulia Carla Immacolata Spolidoro, Hannu Kankaanranta, Emma Goksör, Göran Wennergren, Bright Ibeabughichi Nwaru
doi : 10.1111/pai.13991
Following the “hygiene hypothesis� and the increase in the prevalence of atopic diseases such as allergic rhinitis, a plethora of studies have investigated the role of sibship composition as a protective factor, but findings are conflicting.
“Frequency of fatal and recurrent anaphylaxis due to COW'S milk: A systematic review and meta-analysis of observational studies�
Sabela Pérez-Codesido, Eulalia Grifol-Clar, Marianela Brandoni Petrone, Marta Goyanes Malumbres, Patricia Andrade Garban, Miguel A. Tejedor-Alonso
doi : 10.1111/pai.13977
Cow's milk allergy can result in anaphylactic reactions. The estimated prevalence of cow's milk allergy in developed countries ranges from 0.5% to 3% at age 1 year. Our objective was to perform a systematic review and, if possible, a meta-analysis to assess the frequency of fatal and recurrent anaphylaxis induced by cow's milk.
Editorial comment on “Cost-effectiveness of omalizumab for the treatment of severe pediatric allergic asthma�Results of a real-life study in Spain�
Ayobami Akenroye, Wanda Phipatanakul
doi : 10.1111/pai.13980
Ligelizumab in adolescents with chronic spontaneous urticaria: Results of a dedicated phase 2b randomized clinical trial supported with pharmacometric analysis
Petra Staubach, Montserrat Alvaro-Lozano, Bulent Enis Sekerel, Marcus Maurer, Moshe Ben-Shoshan, Miriam Porter, Eva Hua, Yan Ji, Alis Burciu, Marina Savelieva, Thomas Severin, Anton Drollmann, Andrzej Bienczak
doi : 10.1111/pai.13982
Chronic spontaneous urticaria (CSU), a long-lasting disease in children, impacts their quality of life. We report the results of a phase 2b dose-finding trial of ligelizumab (NCT03437278) and a high-affinity humanized monoclonal anti-IgE antibody, in adolescents with CSU, supported by modeling and simulation analyses, mitigating challenges in pediatric drug development.
Comment on El-Heis et al.
Zelma Cheisa Fuxench, Nandita Mitra, David J. Margolis
doi : 10.1111/pai.13985
Comment on Platts-Mills et al.
Ruperto González-Pérez, Paloma Poza-Guedes, Fernando Pineda
doi : 10.1111/pai.13986
Asthma subtypes and risk of cardiovascular disease: A Mendelian randomization study
Nicole Y. T. Ng, Jane Zhao, Christopher C. Y. Mak, So Lun Lee, Brian H. Y. Chung
doi : 10.1111/pai.13987
Corrigendum to “Nurture, not nature: Impaired skin barrier in infants born to urban households�
doi : 10.1111/pai.13993
