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Issue Highlights page
doi : 10.1016/S0360-3016(23)00471-6
Volume 116, Issue 4, 15 July 2023, Pages A12-A16
Toward Risk Stratification in Adult Extremity and Truncal Soft Tissue Sarcoma Radiation Therapy by Addition and Subtraction
Kilian E. Salerno, MD,* Christine Hill-Kayser, MD,y Daniel J. Indelicato, MD,z Ralph P. Ermoian, MD,x and Elizabeth H. Baldini, MD, MPH
doi : 10.1016/j.ijrobp.2023.02.032
Volume 116, Issue 4, 15 July 2023, Pages 701-704
Radiation Therapy for Borderline Resectable Pancreas Cancer: More to Come or Yesterday's News?
Michael D. Chuong, MD
doi : 10.1016/j.ijrobp.2022.12.005
Volume 116, Issue 4, 15 July 2023, Pages 705-706
Selective Not Routine Use
Matthew H.G. Katz, MD, FACS, FASCO
doi : 10.1016/j.ijrobp.2023.01.019
Volume 116, Issue 4, 15 July 2023, Page 707
Radiation Therapy in Localized Pancreas Cancer: An Ongoing Conundrum
Eileen M. O’Reilly, MD
doi : 10.1016/j.ijrobp.2023.02.016
Volume 116, Issue 4, 15 July 2023, Pages 707-708
The Jury is Still Out
Jessica M. Frakes, MD
doi : 10.1016/j.ijrobp.2023.02.015
Volume 116, Issue 4, 15 July 2023, Page 708
Neoadjuvant Radiation Therapy Should Still Be Considered in Select Patients With Borderline Resectable Pancreas Cancer
Joseph M. Herman, MD, MSc, MHCM, FACR
doi : 10.1016/j.ijrobp.2023.02.051
Volume 116, Issue 4, 15 July 2023, Page 709
When Patience is a Failing: The Case for Patient Reported Outcomes Adoption
Deborah Watkins Bruner, RN, PhD, FAAN
doi : 10.1016/j.ijrobp.2023.01.041
Volume 116, Issue 4, 15 July 2023, Pages 710-716
The State of Clinical Medical Physics and Education in Ghana
Afua A. Yorke, PhD,* Abigail N.M. Quaye, MS,y Francis Hasford, PhD,z and Eric C.D.K. Addison, PhD
doi : 10.1016/j.ijrobp.2023.01.053
Volume 116, Issue 4, 15 July 2023, Pages 717-722
Characteristics of Global Radiation Therapy Trials Between 2017 and 2022: A Cross-Sectional Study
Runzhe Chen, MD, PhD,* Qingqing Xu, MD,* Baiqiang Dong, MD, PhD,* Zan Hou, MD,* Qun Zhang, MD,y Yuan Zhang, MD, PhD,* Xu Liu, MD, PhD,* Yuanyuan Chen, MD, PhD,* and Ming Chen, MD, PhD*
doi : 10.1016/j.ijrobp.2022.12.044
Volume 116, Issue 4, 15 July 2023, Pages 723-728
Recent Trends in Medicare Payments for Outpatient Cancer Care at the End of Life
Constantine A. Mantz, MD,* Catheryn M. Yashar, MD,y Gopal K. Bajaj, MD,z and Howard M. Sandler, MD
doi : 10.1016/j.ijrobp.2023.01.005
Volume 116, Issue 4, 15 July 2023, Pages 729-735
The Cost of Cancer Care at the End of Life: Implications for Centers for Medicare and Medicaid Services and for Radiation Oncology
James B. Yu, MD, MHS
doi : 10.1016/j.ijrobp.2023.02.012
Volume 116, Issue 4, 15 July 2023, Pages 736-738
Pain Response Rates After Conventional Radiation Therapy for Bone Metastases Assessed Using International Consensus Pain Response Endpoints: A Systematic Review and Meta-Analysis of Initial Radiation Therapy and Reirradiation
Nobuki Imano, MD, PhD,* Tetsuo Saito, MD, PhD,y Peter Hoskin, MD,z,x Naoki Nakamura, MD, PhD,k Kei Ito, MD, PhD,{ Atsunori Yorozu, MD, PhD,# Ikuno Nishibuchi, MD, PhD,* Yuji Murakami, MD, PhD,* and Yasushi Nagata, MD, PhD*
doi : 10.1016/j.ijrobp.2023.01.050
Volume 116, Issue 4, 15 July 2023, Pages 739-746
Aging a Decade in a Day: Age Cutoff Bias in Adjuvant Therapy Allocation for Early-Stage Breast Cancer
Wesley J. Talcott, MD, MBA,* Daylian M. Cain, PhD,y Daniel Yang, MD,* Sarah S. Mougalian, MD,z and Suzanne B. Evans, MD, MPH
doi : 10.1016/j.ijrobp.2022.12.057
Volume 116, Issue 4, 15 July 2023, Pages 747-756
Whole Breast Irradiation Versus Intraoperative Electron Radiation Therapy for Breast Conserving Therapy: A Large Mature Single Institution Matched-Pair Evaluation of True Local Relapse, Progression Free Survival, and Overall Survival
Fiorenza De Rose, MD,* Salvatore Mussari, MD,* Lucia Di Brina, MD,* Daniele Ravanelli, MS,y Francesco Ziglio, MS,y Loris Menegotti, MS,y Antonella Ferro, MD,z Alessia Caldara, MD,z Gabriella Berlanda, MD,x Fabio Gasperetti, MD,x Elena Magri, MD,* Laura Bandera, MD,* Patrizia Ferrazza, MD,* Sergio Fersino, MD,* Maria Andolina, MD,* Andrea Martignano, MS,y Anna Delana, MS,y Said Bou Selman, MD,? and Valentina Vanoni, MD*
doi : 10.1016/j.ijrobp.2023.01.049
Volume 116, Issue 4, 15 July 2023, Pages 757-769
Five-Year Patient-Reported Outcomes in NRG Oncology RTOG 0938, Evaluating Two Ultrahypofractionated Regimens for Prostate Cancer
Himanshu R. Lukka, MD,* Snehal Deshmukh, MS,y Deborah W. Bruner, RN, PhD,z Jean-Paul Bahary, MD,x Colleen A.F. Lawton, MD,k Jason A. Efstathiou, MD,{ Rajat J. Kudchadker, PhD, # Lee E. Ponsky, MD,** Samantha A. Seaward, MD,yy Ian S. Dayes, MD,* Darindra D. Gopaul, MD,zz Jeff M. Michalski, MD,xx Guila Delouya, MD,x Irving D. Kaplan, MD,kk Eric M. Horwitz, MD,{{ Mack Roach, III. MD, ## Felix Y. Feng, MD, ## Stephanie L. Pugh, PhD,y Howard M. Sandler, MD,*** and Lisa A. Kachnic, MD
doi : 10.1016/j.ijrobp.2022.12.022
Volume 116, Issue 4, 15 July 2023, Pages 770-778
PSMA-PET/CT-Guided Intensification of Radiation Therapy for Prostate Cancer (PSMAgRT): Findings of Detection Rate, Effect on Cancer Management, and Early Toxicity From a Phase 2 Randomized Controlled Trial
Claire Petit, MD,* Guila Delouya, MD,* Daniel Taussky, MD,* Maroie Barkati, MD,* Carole Lambert, MD,* Marie-Claude Beauchemin, MD,* Sebastien Clavel, MD,y Gary Mok, MD,y Anne-Sophie Gauthier Pare, MD,y Thu-van Nguyen, MD,z Danny Duplan, MD,y Khun Visith Keu, MD,x Fred Saad, MD,? Daniel Juneau, MD,{ and Cynthia Menard, MD
doi : 10.1016/j.ijrobp.2022.12.055
Volume 116, Issue 4, 15 July 2023, Pages 779-787
Upper-Neck Versus Whole-Neck Irradiation at the Contralateral Uninvolved Neck in Patients With Unilateral N3 Nasopharyngeal Carcinoma
Cheng-Long Huang, MD, You-Yu Qiu, MD, Xiao-Jing Du, MD, Gao-Yuan Wang, MD, Rui Guo, MD, Guan-Qun Zhou, MD, Na Liu, MD, Xu Liu, MD, Yan-Ping Mao, MD, Ying Sun, MD, Jun Ma, PhD, and Ling-Long Tang, MD
doi : 10.1016/j.ijrobp.2022.12.041
Volume 116, Issue 4, 15 July 2023, Pages 788-796
Efficacy of Prophylactic High-Dose Gabapentin and Venlafaxine on Reducing Oral Mucositis Pain Among Patients Treated With Chemoradiation for Head and Neck Cancer: A Single-Institution, Phase 2, Randomized Clinical Trial
Sung Jun Ma, MD,* Austin J. Iovoli, MD,* Katy Wang, MA,y Debbie Neimanis, RN, BSN, CCRC,* Kelsey A. Smith, PA,* Kristopher Attwood, PhD,y Mark Farrugia, MD, PhD,* Gregory Hermann, MD, MPH,z and Anurag K. Singh, MD
doi : 10.1016/j.ijrobp.2023.01.047
Volume 116, Issue 4, 15 July 2023, Pages 797-806
Overall Severe Morbidity After Chemo-Radiation Therapy and Magnetic Resonance Imaging-Guided Adaptive Brachytherapy in Locally Advanced Cervical Cancer: Results From the EMBRACE-I Study
Anders Schwartz Vittrup, MD, PhD,* Kathrin Kirchheiner, MSc, PhD,y Richard P€otter, MD,z Lars Ulrik Fokdal, MD, PhD,* Nina Boje Kibsgaard Jensen, MD, PhD,* Sofia Spampinato, PhD,* Christine Haie-Meder, MD,z Maximilian Paul Schmid, MD,y Alina Emiliana Sturdza, MD,y Umesh Mahantshetty, DMRT, MD, DNB,x Peter Hoskin, MD, FRCR,? Barbara Segedin, MD, PhD,{ Kjersti Bruheim, MD, PhD, # Bhavana Rai, MD, DNB,** Ericka Wiebe, MD,yy Elzbieta van der Steen-Banasik, MD,zz Rachel Cooper, MD, FRCR,xx Erik Van Limbergen, MD, PhD,?? Marit Sundset, MD,{{ Bradley Rumwell Pieters, MD, PhD, ## Christian Kirisits, DSc,y Jacob Christian Lindegaard, MD, DMSc,* Ina M. J€urgenliemk-Schulz, MD, PhD,*** Remi Nout, MD, PhD,yyy and Kari Tanderup, PhD*TaggedEnd on behalf of the EMBRACE Collaborative Group
doi : 10.1016/j.ijrobp.2023.01.002
Volume 116, Issue 4, 15 July 2023, Pages 807-824
Treatment Tolerability and Toxicity of Postoperative Proton Beam Therapy for Gynecologic Malignancies: Results of the Prospective Phase 2 APROVE Trial
Nathalie Arians, MD,*,y,z Katja Lindel, MD,x Johannes Krisam,k Jan Tobias Oelmann-Avendano, MD,{ Eva Meixner, MD,*,y,z Laila K€onig, MD,* ,y,z Juliane Hoerner-Rieber, MD,*,y,z Antje Wark, MD,*,y,z Tobias Forster, MD,*,y,z Fabian Weykamp, MD,*,y,z Kristin Lang, MD,*,y,z Andreas Schneeweiss, MD, # Malte Ellerbrock, PhD,** Thomas Mielke,** Klaus Herfarth, MD,*,y,z, **,yy,zz and Juergen Debus, MD, PhD*,y
doi : 10.1016/j.ijrobp.2023.01.004
Volume 116, Issue 4, 15 July 2023, Pages 825-836
Dose-Limiting Pulmonary Toxicity in a Phase 1/2 Study of Radiation and Chemotherapy with Ipilimumab Followed by Nivolumab for Patients With Stage 3 Unresectable Non-Small Cell Lung Cancer
Casey L. Liveringhouse,* Kujtim Latifi,* Amalin G. Asous,* Nghi B. Lam,* Stephen A. Rosenberg,* Thomas J. Dilling,* Gretchen V. MacMillan,* Alberto A. Chiappori,y Eric B. Haura,y Ben Creelan,y Jhanelle E. Gray,y Tawee Tanvetyanon,y Michael R. Shafique,y Andreas N. Saltos,y Ashley A. Weiner,z Jeffrey Clarke,x Christopher R. Kelsey,k Sungjune Kim,* James J. Caudell,* Trevor A. Rose,{ Jose R. Conejo-Garcia, # Jiannong Li,** Michael J. Schell,** Scott J. Antonia,x and Bradford A. Perez,*
doi : 10.1016/j.ijrobp.2023.01.006
Volume 116, Issue 4, 15 July 2023, Pages 837-848
Early-Stage Primary Lung Neuroendocrine Tumors Treated With Stereotactic Body Radiation Therapy: A Multi-Institution Experience
Daniel E. Oliver, MD,* Jose M. Laborde, PhD,y Deepinder P. Singh, MD,z Michael T. Milano, MD, PhD,z Gregory M. Videtic, MDCM, FRCPC, FACR, FASTRO,x Graeme R. Williams, MD,? Michael J. LaRiviere, MD,? Jason W. Chan, MD,{ Gabrielle W. Peters, MD, # Roy H. Decker, MD, PhD, # Pamela Samson, MD, MPHS,** Clifford G. Robinson, MD,** William G. Breen, MD,yy Dawn Owen, MD, PhD,yy Sibo Tian, MD,zz Kristin A. Higgins, MD,zz Doaa Almeldin, MD,xx Salma K. Jabbour, MD,xx Fen Wang, MD,?? G. Daniel Grass, MD, PhD,* Bradford A. Perez, MD,* Thomas J. Dilling, MD,* Jonathan Strosberg, MD,{{ and Stephen A. Rosenberg, MD
doi : 10.1016/j.ijrobp.2023.01.028
Volume 116, Issue 4, 15 July 2023, Pages 849-857
Concurrent Administration of Immune Checkpoint Inhibitors and Single Fraction Stereotactic Radiosurgery in Patients With Non-Small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma Brain Metastases
Eric J. Lehrer, MD, MS,* Roman O. Kowalchuk, MD,y Jason Gurewitz, DO,z Kenneth Bernstein, MS,z Douglas Kondziolka, MD,x Ajay Niranjan, MD, MBA,k Zhishuo Wei, MSc,k L. Dade Lunsford, MD,k Kareem R. Fakhoury, MD,{ Chad G. Rusthoven, MD,{ David Mathieu, MD, # Claire Trudel, MD,** Timothy D. Malouff, MD,yy Henry Ruiz-Garcia, MD,yy Phillip Bonney, MD,zz Lindsay Hwang, MD,xx Cheng Yu, PhD,zz Gabriel Zada, MD,zz Samir Patel, MD,kk Christopher P. Deibert, MD,{{ Piero Picozzi, MD,## Andrea Franzini, MD, ## Luca Attuati, MD, ## Rahul N. Prasad, MD,*** Raju R. Raval, MD, DPhil,*** Joshua D. Palmer, MD,*** Cheng-chia Lee, MD, PhD,yyy Huai-che Yang, MD,yyy William S. Harmsen, MS,zzz Brianna M. Jones, MD,* Sonam Sharma, MD,* Manmeet S. Ahluwalia, MD, MBA,xxx Jason P. Sheehan, MD, PhD,kkk and Daniel M. Trifiletti, MD
doi : 10.1016/j.ijrobp.2023.01.017
Volume 116, Issue 4, 15 July 2023, Pages 858-868
Conformal Radiation Therapy for Ependymoma at Age ≤3 Years: A 25-Year Experience
Gabrielle N. Howe, BS,* Drucilla Y. Edmonston, MD,z Grace C. Dirks, BS,* Frederick A. Boop, MD,y and Thomas E. Merchant, DO, PhD
doi : 10.1016/j.ijrobp.2023.01.016
Volume 116, Issue 4, 15 July 2023, Pages 869-877
Insult to Short-Range White Matter Connectivity in Childhood Brain Tumor Survivors
Adeoye Oyefiade, PhD,* Nadeem Parthab, BSc,* Jovanka Skocic, BA,* Iska Moxon-Emre, PhD,* Uri Tabori, MD,y Eric Bouffet, MD,y Vijay Ramaswamy, MD, PhD,y Susanne Laughlin, MD,z and Donald J. Mabbott, PhD*,xT a g g e d E n d
doi : 10.1016/j.ijrobp.2023.01.024
Volume 116, Issue 4, 15 July 2023, Pages 878-888
A Scalp Dose Threshold for Preventing Permanent Alopecia in Scalp-Avoidance Whole-Brain Irradiation With Volumetric Modulated Arc Radiation Therapy for Pediatric Patients With Medulloblastomas
Daichi Torizuka, MD,* Megumi Uto, MD, PhD,* Katsutsugu Umeda, MD, PhD,y Tatsuya Kamitori, MD,y Atsushi Iwai, MD,y Satoshi Saida, MD, PhD,y Itaru Kato, MD, PhD,y Yohei Mineharu, MD, PhD,z Yoshiki Arakawa, MD, PhD,z Junko Takita, MD, PhD,y and Takashi Mizowaki, MD, PhD
doi : 10.1016/j.ijrobp.2023.01.027
Volume 116, Issue 4, 15 July 2023, Pages 889-893
Yes-Associated Protein 1 Inhibition Induces Immunogenic Cell Death and Synergizes With Radiation and PD-1 Blockade
Yuan Zhuang, PhD, MD,* Yuzi Wang, PhD, MD,*,y Chang Liu, PhD, MD,* Sihan Li, MD,* Shuyan Du, MD,z and Guang Li, PhD, MD*T a g g e d E n d
doi : 10.1016/j.ijrobp.2022.12.045
Volume 116, Issue 4, 15 July 2023, Pages 894-905
Injectable Oxygen Microparticles Boost Radiation–Mediated In Situ Vaccination and Systemic Antitumor Immune Responses
Ryan Patenaude, BS,* Sayeda Yasmin-Karim, PhD,y,z,x Yifeng Peng, PhD,* ,? Kai W. Wucherpfennig, MD, PhD,{,#, ** Wifred Ngwa, PhD,y,z,x John N. Kheir, MD,* ,? and Brian D. Polizzotti, PhD
doi : 10.1016/j.ijrobp.2022.12.051
Volume 116, Issue 4, 15 July 2023, Pages 906-915
Proposing a Clinical Model for RBE Based on Proton Track-End Counts
Nicholas T. Henthorn, PhD,*,y Lydia L. Gardner, MSci,z Adam H. Aitkenhead, PhD,*,x Benjamin C. Rowland, DPhil,*,y Jungwook Shin, PhD,? Edward A.K. Smith, MSc,*,y Michael J. Merchant, PhD,*,y Ranald I. Mackay, PhD,*,x Karen J. Kirkby, PhD,* ,y Pankaj Chaudhary, PhD,z Kevin M. Prise, PhD,z Stephen J. McMahon, PhD,z,1 and Tracy S.A. Underwood, DPhil
doi : 10.1016/j.ijrobp.2022.12.056
Volume 116, Issue 4, 15 July 2023, Pages 916-926
Preclinical Evaluation of 89Zr-Panitumumab for Biology-Guided Radiation Therapy
Arutselvan Natarajan, PhD,* Syamantak Khan, PhD,y Xuanwei Liang,z Hieu Nguyen, PhD,y Neeladrisingha Das, PhD,y David Anders, PhD,* Noeen Malik, PhD,* Oluwaseyi M. Oderinde, PhD,x Frederick T. Chin, PhD,* Eben Rosenthal, MD,k and Guillem Pratx, PhD
doi : 10.1016/j.ijrobp.2023.01.007
Volume 116, Issue 4, 15 July 2023, Pages 927-934
Commissioning of Helium Ion Therapy and the First Patient Treatment With Active Beam Delivery
Thomas Tessonnier, PhD,* ,y,z Swantje Ecker, MSc,* Judith Besuglow, MSc,y,z,x,k Jakob Naumann, PhD,* Stewart Mein, PhD,y,z,x,{ Friderike K. Longarino, MSc,y,z,x,k Malte Ellerbrock, PhD,* Benjamin Ackermann, MSc,* Marcus Winter, PhD,* Stephan Brons, PhD,* Abdallah Qubala, MSc,* ,z,# Thomas Haberer, PhD,* J€urgen Debus, MD, PhD,* ,y,z,x,{ Oliver J€akel, PhD,*,z, ** and Andrea Mairani
doi : 10.1016/j.ijrobp.2023.01.015
Volume 116, Issue 4, 15 July 2023, Pages 935-948
An Integrated Physical Optimization Framework for Proton Stereotactic Body Radiation Therapy FLASH Treatment Planning Allows Dose, Dose Rate, and Linear Energy Transfer Optimization Using Patient-Specific Ridge Filters
Ruirui Liu, PhD,* Serdar Charyyev, PhD,* Niklas Wahl, PhD,y,z Wei Liu, PhD,x Minglei Kang, PhD,k Jun Zhou, PhD,* Xiaofeng Yang, PhD,* Filipa Baltazar, PhD,y,{ Martina Palkowitsch, PhD,y,z,# Kristin Higgins, MD,* William Dynan, PhD,* Jeffrey Bradley, MD,* and Liyong Lin, PhD
doi : 10.1016/j.ijrobp.2023.01.048
Volume 116, Issue 4, 15 July 2023, Pages 949-959
In Regard to Ahmed et al.
Nur Nimet Saliha Akdag, MD Melis Gultekin, MD Ferah Yildiz, MD
doi : 10.1016/j.ijrobp.2023.03.058
Volume 116, Issue 4, 15 July 2023, Page 960
In Reply to Akdag et al.
Safia K. Ahmed, MD
doi : 10.1016/j.ijrobp.2023.03.061
Volume 116, Issue 4, 15 July 2023, Pages 960-961
In Regard to Woodward and Mitchell
Frank Vicini, MD, FACR, FASTRO, FABSTroy Bremer, PhDChirag Shah, MD
doi : 10.1016/j.ijrobp.2023.03.068
Volume 116, Issue 4, 15 July 2023, Pages 961-963
In Regard to Vittrup et al.
Naoya Murakami, MD, PhDYasuhisa Terao, MD, PhDNaoto Shikama, MD, PhD
doi : 10.1016/j.ijrobp.2023.03.072
Volume 116, Issue 4, 15 July 2023, Pages 963-964
In Reply to Murakami et al.
Anders Schwartz Vittrup, MD, PhD Sofia Spampinato, PhD Nina Boje Kibsgaard Jensen, MD, PhD Kari Tanderup, PhDKathrin Kirchheiner, MSc, PhD Richard P€otter, MDRemi Nout, MD, PhDIna M. J€urgenliemk-Schulz, MD, PhD
doi : 10.1016/j.ijrobp.2023.03.070
Volume 116, Issue 4, 15 July 2023, Pages 964-965
